Registered substances

Registered substances

Registered substances

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-{[(3S,4S,6R,8R)-8-methoxy-4,8-dimethyl-1,5-dioxaspiro[2.5]oct-6-yl]oxy}-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 3,4,6-trideoxy-3-(dimethylamino)--D-xylo-hexopyranoside
953-425-7 217500-75-9 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
Reaction mass of 1,1,1,3,5,5,5-heptamethyltrisiloxane and 1,1,1,3,5,7,7,7-octamethyltetrasiloxane and hexamethyldisiloxane
953-427-8 - Active Intermediate Individual Intermediate use only 11-12-2020 View substance registered dossier
Reaction mass of 1-(2-hydroxyphenyl)-ethanone and 1-(3-methyl-2-benzofuranyl)-ethanone
953-441-4 - Active Intermediate Joint Intermediate use only 27-01-2021 View substance registered dossier
Reaction mass of [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aR,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate and [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
953-451-9 - Active Full Joint ≥ 10 to < 100 tonnes 09-05-2022 View substance registered dossier
Cerium gadolinium oxide
953-470-2 - Active Full Individual ≥ 1 to < 10 tonnes 03-02-2022 View substance registered dossier
Reaction mass of 3-({1-[(1-methoxypropan-2-yl)oxy]propan-2-yl}oxy)prop-1-ene and 3-{[1-(2-methoxypropoxy)propan-2-yl]oxy}prop-1-ene
953-504-6 - Active Intermediate Individual Intermediate use only 26-03-2021 View substance registered dossier
((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one
953-513-5 - Active Full Joint ≥ 0 to < 10 tonnes 04-08-2021 View substance registered dossier
oxalic acid-4-amino-3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (1/1)
953-548-6 - Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
Fatty acids, C16 and C18-unsaturated, methyl esters, chlorinated
953-553-3 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 15-04-2022 View substance registered dossier
Fatty acids, C16 and C18-unsaturated, methyl esters, chlorinated
953-553-3 - Active Full Individual ≥ 1 to < 10 tonnes 30-09-2021 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-13-{[(3S,4S,6R,8R)-8-methoxy-4,8-dimethyl-1,5-dioxaspiro[2.5]oct-6-yl]oxy}-3,5,8,10,12,14-hexamethyl-15-oxo-1-oxa-6-azacyclopentadecan-11-yl 3,4,6-trideoxy-3-(dimethylamino)--D-xylo-hexopyranoside 953-425-7 217500-75-9 - View substance registered dossier
[Confidential] - - - Reaction mass of 1,1,1,3,5,5,5-heptamethyltrisiloxane and 1,1,1,3,5,7,7,7-octamethyltetrasiloxane and hexamethyldisiloxane 953-427-8 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Reaction mass of 1-(2-hydroxyphenyl)-ethanone and 1-(3-methyl-2-benzofuranyl)-ethanone 953-441-4 - - View substance registered dossier
seppic sa 50 boulevard National CS 90020 92257 La Garenne Colombes ile de france France France Active Reaction mass of [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aR,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate and [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate 953-451-9 - 2022 View substance registered dossier
Intertek Italia SpA_IFB Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO, Milano Italy Italy Active Reaction mass of [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (1S,2R,4aS,6aR,6aR,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylate and [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8R,8aR,9R,10R,11R,12aR,14bS)-8,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate 953-451-9 - - View substance registered dossier
RHODIA OPERATIONS 9 rue des Cuirassiers Immeuble Silex 2 Solvay 69003 LYON France France Active Cerium gadolinium oxide 953-470-2 - - View substance registered dossier
Dow Silicones Belgium SPRL OR-1 rue Jules Bordet Parc industriel C 7180 Seneffe Belgium Belgium Active Reaction mass of 3-({1-[(1-methoxypropan-2-yl)oxy]propan-2-yl}oxy)prop-1-ene and 3-{[1-(2-methoxypropoxy)propan-2-yl]oxy}prop-1-ene 953-504-6 - 2020; 2021 View substance registered dossier
Yordas GmbH Äuβere Nürnberger Straβe 62 91301 Forchheim Germany Germany Active ((4S,4aR,7S,7aR)-4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one 953-513-5 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active oxalic acid-4-amino-3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (1/1) 953-548-6 - - View substance registered dossier
ALTAIR CHIMICA SPA VIA MOIE VECCHIE 13 56048 SALINE DI VOLTERRA (PI) Italy Italy Active Fatty acids, C16 and C18-unsaturated, methyl esters, chlorinated 953-553-3 - 2022 View substance registered dossier
ICC Industries, B.V. Hullenbergweg 278 1101 BV Amsterdam The Netherlands Netherlands Netherlands Active Fatty acids, C16 and C18-unsaturated, methyl esters, chlorinated 953-553-3 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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