Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Diethylcarbamazine
202-023-3 90-89-1 Active Intermediate Individual Intermediate use only 20-01-2015 View substance registered dossier
Diethylenetriaminepentaacetic acid dianhydride
607-286-1 23911-26-4 Active Intermediate Individual Intermediate use only 05-10-2017 View substance registered dossier
diethylmethoxyborane
425-380-9 7397-46-8 Active Intermediate Individual Intermediate use only 05-11-2014 View substance registered dossier
difluoro(fluorosulphonyl)acetyl fluoride and 3,3,4,4-tetrafluoro-1,2-oxathietane 2,2-dioxide
947-152-2 - Active Intermediate Individual Intermediate use only 08-03-2018 View substance registered dossier
difluoro-2,2,4,5-tetrafluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}acetyl fluoride
948-548-8 1260592-86-6 Active Intermediate Individual Intermediate use only 20-02-2019 View substance registered dossier
Dihexyl 2-hydroxy-5-methoxybenzene-1,4-bis(5,5-dimethylvalerate)
IGAPERM 2876
401-180-7 89829-20-9 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
dihexyldecyl citrate;dihexyloctyl citrate;dioctylhexyl citrate;reaction mass of: trihexyl citrate
430-290-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dihydro-3-(tripropenyl)furan-2,5-dione
295-556-6 92077-08-2 Active Full Individual ≥ 10 to < 100 tonnes 19-02-2016 View substance registered dossier
Diindolo(3,2-b:3',2'-m)triphenodioxazine, 8,18-dichloro-5,15-diethyl- 5,15-dihydro-, (5-methyl-1H-imidazol-4-yl)methyl derivatives
404-110-3 128973-76-2 Active Full Individual ≥ 10 to < 100 tonnes 31-01-2017 View substance registered dossier
Diisobutyl maleate
238-102-4 14234-82-3 Active Intermediate Individual Intermediate use only 22-05-2013 View substance registered dossier
Diisobutyl phthalate 201-553-2 84-69-5 Cease Manufacture Full Individual Cease manufacture 15-09-2010 View substance registered dossier
Diisobutyl phthalate 201-553-2 84-69-5 Active Intermediate Individual Intermediate use only 03-01-2013 View substance registered dossier
Diisobutyl phthalate 201-553-2 84-69-5 Active Intermediate Individual Intermediate use only 22-07-2013 View substance registered dossier
Diisobutyl phthalate 201-553-2 84-69-5 Cease Manufacture Intermediate Individual Cease manufacture 11-02-2014 View substance registered dossier
Diisononylamine
249-029-2 28454-70-8 Active Intermediate Individual Intermediate use only 23-02-2016 View substance registered dossier
Diisopentyl phthalate
210-088-4 605-50-5 Cease Manufacture Full Individual Cease manufacture 25-03-2021 View substance registered dossier
Diisopropanolammonium p-toluenesulphonate
603-351-3 129678-02-0 Active Full Individual ≥ 1 to < 10 tonnes 05-05-2018 View substance registered dossier
Dilithium 7-acetamido-1-hydroxy-2-(4-((2-sulfonatooxy)ethylsulfonyl)phenylazo)naphthalene-3-sulfonate
REACTIVE ORANGE F-64 258 FW
401-010-1 106027-83-2 Cease Manufacture NONS Individual Cease manufacture 20-12-2010 View substance registered dossier
Dilithium disodium (5,5'-diamino-(μ-4,4'-dihydroxy-1:2-κ-2,O4,O4',-3,3'-[3,3'-dihydroxy-1:2-κ-2-O3,O3'-biphenyl-4,4'-ylenebisazo-1:2-(N3,N4-η:N3',N4'-η)]-dinaphthalene-2,7-disulfonato(8)))dicuprate(2-)
BLUE GS 1259 R5
407-230-4 126637-70-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Dilutetium oxide silicate
235-337-4 12168-86-4 Active Full Individual ≥ 1 to < 10 tonnes 07-05-2019 View substance registered dossier
DIMETHYL
428-270-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Dimethyl (2-acetoxyethyl)phosphonate
254-301-9 39118-50-8 Active Intermediate Individual Intermediate use only 09-11-2012 View substance registered dossier
dimethyl (2S)-2-hydroxysuccinate
432-310-0 617-55-0 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
Dimethyl 2,2'-[(4-methylbenzene-1,2-diyl)bis(oxy)]diacetate
700-270-6 52589-39-6 Active Intermediate Individual Intermediate use only 10-02-2009 View substance registered dossier
Dimethyl 3,3'-(N-(4-(4-bromo-2,6-dicyanophenylazo)-3-hydroxyphenyl)imino)dipropionate
DISPERSE RED FC 38583
407-310-9 122630-55-1 Active NONS Individual Tonnage data confidential 18-07-2011 View substance registered dossier
Dimethyl 3-oxoglutarate
217-385-8 1830-54-2 Active Intermediate Individual Intermediate use only 03-05-2013 View substance registered dossier
Dimethyl disulphide
210-871-0 624-92-0 Active Intermediate Individual Intermediate use only 15-11-2012 View substance registered dossier
Dimethyl maleate
210-848-5 624-48-6 Active Intermediate Individual Intermediate use only 09-06-2010 View substance registered dossier
Dimethyl malonate
203-597-8 108-59-8 Active Intermediate Individual Intermediate use only 16-04-2012 View substance registered dossier
Dimethyl methylphosphonate
212-052-3 756-79-6 Active Intermediate Individual Intermediate use only 26-08-2010 View substance registered dossier
Dimethyl phthalate
205-011-6 131-11-3 No longer Valid Full Individual No longer valid 18-12-2015 View substance registered dossier
Dimethyl sebacate
203-431-4 106-79-6 Active Intermediate Individual Intermediate use only 29-05-2013 View substance registered dossier
Dimethyl succinate
203-419-9 106-65-0 Active Intermediate Individual Intermediate use only 08-03-2012 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 16-12-2014 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 19-10-2012 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 13-06-2014 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Cease Manufacture Intermediate Individual Cease manufacture 10-12-2014 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Active Intermediate Individual Intermediate use only 07-01-2015 View substance registered dossier
Dimethyl sulphate
201-058-1 77-78-1 Cease Manufacture Intermediate Individual Cease manufacture 10-12-2014 View substance registered dossier
dimethyl(phenyl)sulfanium perfluorobutanesulfonate 452-310-4 220133-51-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
dimethyl-1-{[2-methoxy-5-(2-methyl-butoxycarbonyl)phenylcarbamoyl]-[2-octadecyl-1,1-dioxo-1,2,4-benzothiadiazin-3-yl]methyl} imidazole-4,5-dicarboxylate
443-910-7 1380163-91-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Dimethylamine-borane (1:1)
200-823-7 74-94-2 Active Full Individual Tonnage data confidential 06-04-2018 View substance registered dossier
Dimethylaminopropylmethacrylamide, dodecyl bromide
- - Active Full Individual ≥ 0 to < 10 tonnes 31-03-2022 View substance registered dossier
Dimethylcarbamoyl chloride
201-208-6 79-44-7 Active Intermediate Individual Intermediate use only 01-04-2011 View substance registered dossier
Dimethylcyclopropane-1,1-dicarboxylate
CDM
414-240-2 6914-71-2 Active Intermediate Individual Intermediate use only 19-10-2010 View substance registered dossier
Dimethyloctadecyl(3-sulphopropyl)ammonium hydroxide
236-124-9 13177-41-8 Active Full Individual Tonnage data confidential 16-05-2022 View substance registered dossier
dinotefuran (ISO); 1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl)guanidine
605-399-0 165252-70-0 Active Full Individual ≥ 10 to < 100 tonnes 10-03-2020 View substance registered dossier
DIOLAT
439-580-9 - Active Intermediate Individual Intermediate use only 24-09-2010 View substance registered dossier
Dipentaerythritol hexaesters of 3,5,5-trimethylhexanoic, n-decanoic, n-octanoic, and n-pentanoic acids
701-334-6 - Active Full Individual ≥ 0 to < 10 tonnes 20-04-2020 View substance registered dossier
diphenoxymethylenecyanamide
427-300-8 79463-77-7 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Diethylcarbamazine 202-023-3 90-89-1 - View substance registered dossier
GE Healthcare AS Nycoveien 1 Postboks 4220 Nydalen 0401 Oslo Oslo Norway Norway Active Diethylenetriaminepentaacetic acid dianhydride 607-286-1 23911-26-4 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active diethylmethoxyborane 425-380-9 7397-46-8 - View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active difluoro(fluorosulphonyl)acetyl fluoride and 3,3,4,4-tetrafluoro-1,2-oxathietane 2,2-dioxide 947-152-2 - - View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active difluoro-2,2,4,5-tetrafluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}acetyl fluoride 948-548-8 1260592-86-6 2019 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Cease Manufacture Dihexyl 2-hydroxy-5-methoxybenzene-1,4-bis(5,5-dimethylvalerate) 401-180-7 89829-20-9 2018 View substance registered dossier
Sasol Germany GmbH Anckelmannsplatz 1 D-20537 Hamburg Germany Germany Active dihexyldecyl citrate;dihexyloctyl citrate;dioctylhexyl citrate;reaction mass of: trihexyl citrate 430-290-8 - - View substance registered dossier
Clariant Ibérica Producción S.A. Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain Spain Active Dihydro-3-(tripropenyl)furan-2,5-dione 295-556-6 92077-08-2 2013; 2015; 2016 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active Diindolo(3,2-b:3',2'-m)triphenodioxazine, 8,18-dichloro-5,15-diethyl- 5,15-dihydro-, (5-methyl-1H-imidazol-4-yl)methyl derivatives 404-110-3 128973-76-2 2012; 2016; 2017 View substance registered dossier
EOC Surfactants NV Durmakker 35 B 9940 Evergem Oost Vlaanderen Belgium Belgium Active Diisobutyl maleate 238-102-4 14234-82-3 - View substance registered dossier
LORD Germany GMBH Ottostrasse 28 41836 Hueckelhoven North Rhine - Westphalia Germany Germany Cease Manufacture Diisobutyl phthalate 201-553-2 84-69-5 2019 View substance registered dossier
DEZA a.s. Masarykova 753 75701 Valasske Mezirici Czech Republic Czech Republic Active Diisobutyl phthalate 201-553-2 84-69-5 2013 View substance registered dossier
Grace Catalysts & Materials, S.L.U. Carretera N-340, km 1.156 43006 Tarragona Spain Spain Active Diisobutyl phthalate 201-553-2 84-69-5 2012; 2013 View substance registered dossier
GRACE GmbH (OR1) In der Hollerhecke 1 67547 Worms Germany Germany Cease Manufacture Diisobutyl phthalate 201-553-2 84-69-5 2014 View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Active Diisononylamine 249-029-2 28454-70-8 - View substance registered dossier
EURENCO Bofors AB Kontorsvägen 6 SE-691 86 Karlskoga Sweden Sweden Cease Manufacture Diisopentyl phthalate 210-088-4 605-50-5 2021 View substance registered dossier
King Industries International Science Park 402 1098 XH Amsterdam Amsterdam Netherlands Netherlands Active Diisopropanolammonium p-toluenesulphonate 603-351-3 129678-02-0 - View substance registered dossier
CFB Chemische Fabrik Brunsbüttel GmbH Kühlturmstrasse 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Cease Manufacture Dilithium 7-acetamido-1-hydroxy-2-(4-((2-sulfonatooxy)ethylsulfonyl)phenylazo)naphthalene-3-sulfonate 401-010-1 106027-83-2 2016 View substance registered dossier
Clariant Production UK Ltd Clariant House, Unit 2 Rawdon Park LS19 7BA Yeadon Leeds United Kingdom United Kingdom Active Dilithium disodium (5,5'-diamino-(μ-4,4'-dihydroxy-1:2-κ-2,O4,O4',-3,3'-[3,3'-dihydroxy-1:2-κ-2-O3,O3'-biphenyl-4,4'-ylenebisazo-1:2-(N3,N4-η:N3',N4'-η)]-dinaphthalene-2,7-disulfonato(8)))dicuprate(2-) 407-230-4 126637-70-5 - View substance registered dossier
RHODIA OPERATIONS 9 rue des Cuirassiers Immeuble Silex 2 Solvay 69003 LYON France France Active Dilutetium oxide silicate 235-337-4 12168-86-4 2018; 2019 View substance registered dossier
- - - - DIMETHYL 428-270-9 - - View substance registered dossier
Curia Germany GmbH Industrial Park Hoechst Building D569 65926 Frankfurt Germany Germany Active Dimethyl (2-acetoxyethyl)phosphonate 254-301-9 39118-50-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active dimethyl (2S)-2-hydroxysuccinate 432-310-0 617-55-0 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active Dimethyl 2,2'-[(4-methylbenzene-1,2-diyl)bis(oxy)]diacetate 700-270-6 52589-39-6 2009 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active Dimethyl 3,3'-(N-(4-(4-bromo-2,6-dicyanophenylazo)-3-hydroxyphenyl)imino)dipropionate 407-310-9 122630-55-1 2011 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active Dimethyl 3-oxoglutarate 217-385-8 1830-54-2 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Unit 1 Ardee Business Park, Hale Street Co. Louth Ardee Ireland Ireland Active Dimethyl disulphide 210-871-0 624-92-0 2012 View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active Dimethyl maleate 210-848-5 624-48-6 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Dimethyl malonate 203-597-8 108-59-8 - View substance registered dossier
THOR GmbH Landwehrstrasse 1 D-67346 Speyer Rheinland-Pfalz Germany Germany Active Dimethyl methylphosphonate 212-052-3 756-79-6 - View substance registered dossier
Koopman International B.V. Distelweg 88 1031 HH Amsterdam Netherlands Netherlands No longer Valid Dimethyl phthalate 205-011-6 131-11-3 2017 View substance registered dossier
3V Sigma S.p.A Torquato Tasso 58 24121 Bergamo Italy Italy Active Dimethyl sebacate 203-431-4 106-79-6 - View substance registered dossier
Only representative (No publishable name) - - Active Dimethyl succinate 203-419-9 106-65-0 - View substance registered dossier
AAKO BV Arnhemseweg 87 3832 GK Leusden Netherlands Netherlands Active Dimethyl sulphate 201-058-1 77-78-1 2014 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Dimethyl sulphate 201-058-1 77-78-1 2012 View substance registered dossier
CHT Germany GmbH Bismarckstr. 102 72072 Tuebingen Germany Germany Active Dimethyl sulphate 201-058-1 77-78-1 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Cease Manufacture Dimethyl sulphate 201-058-1 77-78-1 2019 View substance registered dossier
OQEMA LIMITED (IRELAND) Millienium House Athlone Road N39YW40 Ballymahon, Co Longford Ireland Ireland Active Dimethyl sulphate 201-058-1 77-78-1 2015 View substance registered dossier
[Confidential] - - - Dimethyl sulphate 201-058-1 77-78-1 - View substance registered dossier
- - - - dimethyl(phenyl)sulfanium perfluorobutanesulfonate 452-310-4 220133-51-7 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Cease Manufacture dimethyl-1-{[2-methoxy-5-(2-methyl-butoxycarbonyl)phenylcarbamoyl]-[2-octadecyl-1,1-dioxo-1,2,4-benzothiadiazin-3-yl]methyl} imidazole-4,5-dicarboxylate 443-910-7 1380163-91-6 2020 View substance registered dossier
[Confidential] - - - Dimethylamine-borane (1:1) 200-823-7 74-94-2 - View substance registered dossier
SNF SA ZAC de Milieux 42163 Andrézieux France France Active Dimethylaminopropylmethacrylamide, dodecyl bromide - - - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active Dimethylcarbamoyl chloride 201-208-6 79-44-7 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active Dimethylcyclopropane-1,1-dicarboxylate 414-240-2 6914-71-2 2010 View substance registered dossier
Atotech Deutschland GmbH & Co. KG Erasmusstraße 20 10553 Berlin Germany Germany Active Dimethyloctadecyl(3-sulphopropyl)ammonium hydroxide 236-124-9 13177-41-8 2022 View substance registered dossier
LKC Chem-Regs Ltd. Marine House Clanwilliam Place 2 Dublin Ireland Ireland Active dinotefuran (ISO); 1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl)guanidine 605-399-0 165252-70-0 2018; 2020 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active DIOLAT 439-580-9 - 2010 View substance registered dossier
Zschimmer & Schwarz GmbH & Co KG Max-Schwarz-Str. 3-5 56112 Lahnstein Germany Germany Active Dipentaerythritol hexaesters of 3,5,5-trimethylhexanoic, n-decanoic, n-octanoic, and n-pentanoic acids 701-334-6 - 2020 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture diphenoxymethylenecyanamide 427-300-8 79463-77-7 2015 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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