Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
4-(1-oxo-2-propenyl)-morpholine
ACRYLOYLMORPHOLIN
418-140-1 5117-12-4 Cease Manufacture Full Individual Cease manufacture 21-09-2015 View substance registered dossier
4-(2,2-diphenylethenyl)-N,N-di-phenylbenzenamine
RTD-56
421-390-2 89114-90-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide)
GLIMEPIRID-SULFONAMID; GLIMEPIRIDE SULFONAMIDE
411-850-0 119018-29-0 Active Intermediate Individual Intermediate use only 13-02-2018 View substance registered dossier
4-(2-acryloyloxy-ethoxy) benzophenone
836-681-3 22421-66-5 Active Full Individual ≥ 0 to < 10 tonnes 03-05-2021 View substance registered dossier
4-(2-Benzyloxyethoxy)-benzophenone
938-331-6 341527-03-5 Active Intermediate Individual Intermediate use only 09-03-2021 View substance registered dossier
4-(2-carboxymethylthio)ethoxy-1-hydroxy-5-isobutyloxycarbonylamino-N-(3-dodecyloxypropyl)-2-naphthamide
UC-135
420-730-7 115625-86-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile
811-458-3 1197377-47-1 Active Intermediate Individual Intermediate use only 08-05-2018 View substance registered dossier
4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid
201-901-3 89-36-1 Active Full Individual ≥ 1 to < 10 tonnes 19-02-2015 View substance registered dossier
4-(3-triethoxysilylpropoxy)-2-hydroxybenzophenone
431-490-8 79876-59-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(4'-Trifluoromethylphenyl)benzaldehyde
473-430-3 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4,4-dimethyl-3-oxo-pyrazolidin-1-yl)-benzoic acid
CARBODIM
413-120-7 107144-30-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride
TRIAZIMOCH
447-230-1 3945-69-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile
INDAR
406-140-2 114369-43-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide
425-850-3 125971-96-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(4-hydroxyphenyl)cyclohexanone
4-(4'-HYDROXYPHENYL)-CYCLOHEXANON
423-920-8 105640-07-1 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4-methoxyphenyl)butan-2-one
203-184-2 104-20-1 Active Intermediate Individual Intermediate use only 05-12-2016 View substance registered dossier
4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester
840-712-6 1034975-53-5 Active Intermediate Individual Intermediate use only 26-06-2019 View substance registered dossier
4-(4-tolyloxy)biphenyl
JKY-120
405-730-7 51601-57-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene
430-860-6 - Active NONS Individual Tonnage data confidential 05-11-2019 View substance registered dossier
4-(5-ethoxyheptyl)perhydropentalen-2-one
ETHOCYN
419-880-6 99778-68-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate
951-814-6 - Active Intermediate Individual Intermediate use only 03-01-2020 View substance registered dossier
4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester)
425-120-4 83847-14-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(benzylamino)-5-methyl-2(1H)-pyridinon
809-933-5 95306-62-0 Active Intermediate Individual Intermediate use only 21-08-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture 4-(1-oxo-2-propenyl)-morpholine 418-140-1 5117-12-4 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-(2,2-diphenylethenyl)-N,N-di-phenylbenzenamine 421-390-2 89114-90-9 - View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active 4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide) 411-850-0 119018-29-0 2010; 2012; 2018 View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active 4-(2-acryloyloxy-ethoxy) benzophenone 836-681-3 22421-66-5 2021 View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active 4-(2-Benzyloxyethoxy)-benzophenone 938-331-6 341527-03-5 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Cease Manufacture 4-(2-carboxymethylthio)ethoxy-1-hydroxy-5-isobutyloxycarbonylamino-N-(3-dodecyloxypropyl)-2-naphthamide 420-730-7 115625-86-0 2019 View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active 4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile 811-458-3 1197377-47-1 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 4-(3-methyl-5-oxo-2-pyrazolin-1-yl)benzenesulphonic acid 201-901-3 89-36-1 - View substance registered dossier
Momentive Performance Materials GmbH Chempark, Building V7 PO 4502311119 51368 Leverkusen NRW Germany Germany Active 4-(3-triethoxysilylpropoxy)-2-hydroxybenzophenone 431-490-8 79876-59-8 - View substance registered dossier
- - - - 4-(4'-Trifluoromethylphenyl)benzaldehyde 473-430-3 - - View substance registered dossier
- - - - 4-(4,4-dimethyl-3-oxo-pyrazolidin-1-yl)-benzoic acid 413-120-7 107144-30-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride 447-230-1 3945-69-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-(4-chlorophenyl)-2-phenyl-2-[(1H-1,2,4-triazol-1-yl)methyl]butanenitrile 406-140-2 114369-43-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-(4-fluorophenyl)-2-(2-methyl-1-oxopropyl)-4-oxo-3,N-diphenylbutanamide 425-850-3 125971-96-2 - View substance registered dossier
- - - - 4-(4-hydroxyphenyl)cyclohexanone 423-920-8 105640-07-1 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 4-(4-methoxyphenyl)butan-2-one 203-184-2 104-20-1 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 4-(4-Methylpiperazin-1-yl)-2-[(tetrahydropyran-4-yl)(2,2,2-trifluoroacetyl)amino]benzoic acid tert-butyl ester 840-712-6 1034975-53-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 4-(4-tolyloxy)biphenyl 405-730-7 51601-57-1 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene 430-860-6 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-(5-ethoxyheptyl)perhydropentalen-2-one 419-880-6 99778-68-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate 951-814-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-(6-acryloyloxyhexyloxy)-benzoic acid (4-cyanophenyl ester) 425-120-4 83847-14-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active 4-(benzylamino)-5-methyl-2(1H)-pyridinon 809-933-5 95306-62-0 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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