Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.


REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

No results were found
628-472-9 188111-79-7 Active Intermediate Joint Intermediate use only 12-01-2022 View substance registered dossier
606-048-4 18531-94-7 Active Intermediate Joint Intermediate use only 11-11-2019 View substance registered dossier
(R)-1-(1-Naphthyl)ethylamine (R)-Mandelate
600-816-2 1073144-62-3 Active Intermediate Joint Intermediate use only 17-01-2018 View substance registered dossier
(R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid
941-846-9 - Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
424-280-2 51594-55-9 Active Intermediate Joint Intermediate use only 20-03-2018 View substance registered dossier
217-285-4 1798-60-3 Active Intermediate Individual Intermediate use only 08-05-2013 View substance registered dossier
215-808-0 1415-73-2 Active Intermediate Joint Intermediate use only 06-04-2018 View substance registered dossier
203-368-2 106-16-1 Active Intermediate Joint Intermediate use only 18-05-2016 View substance registered dossier
224-815-8 4501-58-0 Active Intermediate Joint Intermediate use only 30-11-2021 View substance registered dossier
(R)-2-(2,5-difluorophenyl)pyrrolidine (R)-2-hydroxysuccinate
845-727-1 1919868-77-1 Active Intermediate Individual Intermediate use only 18-01-2022 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (R)-(−)-3-Amino-1-Boc-piperidine 628-472-9 188111-79-7 - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active (R)-1,1'-Binaphthalene-2,2'-diol 606-048-4 18531-94-7 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-1-(1-Naphthyl)ethylamine (R)-Mandelate 600-816-2 1073144-62-3 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid 941-846-9 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (R)-1-chloro-2,3-epoxypropane 424-280-2 51594-55-9 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (R)-1-hydroxy-1-phenylacetone 217-285-4 1798-60-3 2013 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active (R)-10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one 215-808-0 1415-73-2 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (R)-12-hydroxy-N-(2-hydroxyethyl)oleamide 203-368-2 106-16-1 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 2021 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active (R)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 224-815-8 4501-58-0 2013 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (R)-2-(2,5-difluorophenyl)pyrrolidine (R)-2-hydroxysuccinate 845-727-1 1919868-77-1 2022 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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