Registered substances

Registered substances

Registered substances

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
4-[(3-hydroxypropyl)amino]-3-nitrophenol
PLAKATROT Z; ROT BN
406-305-9 92952-81-3 Active Full Joint ≥ 1 to < 10 tonnes 06-07-2021 View substance registered dossier
4-[(3-hydroxypropyl)amino]-3-nitrophenol
PLAKATROT Z; ROT BN
406-305-9 92952-81-3 Active NONS Joint Tonnage data confidential 18-12-2008 View substance registered dossier
4-[(4,8-disulpho-2-naphthyl)azo]naphthalene-1-diazonium chloride
267-995-3 67969-94-2 Active Intermediate Joint Intermediate use only 11-06-2019 View substance registered dossier
4-[(4-amino-5-methoxy-o-tolyl)azo]-5-[(phenylsulphonyl)oxy]naphthalene-2,7-disulphonic acid
204-190-8 117-44-2 Active Intermediate Joint Intermediate use only 15-03-2018 View substance registered dossier
4-[(4-amino-m-tolyl)(4-imino-3-methylcyclohexa-2,5-dien-1-ylidene)methyl]-o-toluidine monohydrochloride
221-831-7 3248-91-7 Active Full Joint ≥ 1 to < 10 tonnes 18-10-2017 View substance registered dossier
4-[(4-chloro-2-nitrophenyl)azo]-3-hydroxy-N-(2-methylphenyl)naphthalene-2-carboxamide
229-314-8 6471-50-7 Cease Manufacture Full Joint Cease manufacture 27-03-2015 View substance registered dossier
4-[(4-ethoxyphenyl)amino]-N,N-dimethyl-3-nitrobenzenesulphonamide
266-648-3 67338-59-4 Active Full Joint ≥ 10 to < 100 tonnes 28-03-2022 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate
- - Active Full Joint Tonnage data confidential 04-12-2017 View substance registered dossier
4-[(5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)azo]-2,5-dichlorobenzenesulphonic acid
235-473-4 12239-15-5 Active Full Joint ≥ 1 to < 10 tonnes 17-01-2018 View substance registered dossier
4-[(5-carbamoyl-o-tolyl)azo]-3-hydroxynaphth-2-anilide
240-454-9 16403-84-2 Active Full Joint ≥ 1 to < 10 tonnes 12-09-2018 View substance registered dossier
4-[(6-amino-1-hydroxy-3-sulpho-2-naphthyl)azo]-3-hydroxy-7-nitronaphthalene-1-sulphonic acid
204-203-7 117-69-1 Cease Manufacture Intermediate Joint Cease manufacture 23-03-2012 View substance registered dossier
4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
928-806-6 - Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
4-[(E)-2-nitroethenyl]-1H-indole
634-890-2 49839-99-8 Active Intermediate Joint Intermediate use only 23-04-2018 View substance registered dossier
4-[(morpholinothio)thioxomethyl]morpholine
237-335-9 13752-51-7 Active Full Joint ≥ 10 to < 100 tonnes 02-06-2022 View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride
AMPA
447-990-4 400827-64-7 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
4-[2-(diethylamino)ethoxy]benzophenone
212-348-2 796-77-0 Active Intermediate Joint Intermediate use only 13-10-2016 View substance registered dossier
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol
700-516-2 93413-62-8 Active Intermediate Joint Intermediate use only 07-04-2021 View substance registered dossier
4-[2-(methoxymethyl)-3-methyl-1-methylene-but-2-enyl]-1H-tetrazol-5-one
826-908-4 1472631-98-3 Active Intermediate Joint Intermediate use only 28-10-2020 View substance registered dossier
4-[2-[4-(2-benzoxazoleyl)phenyl]vinyl]benzoic acid
225-303-7 4763-79-5 Active Intermediate Joint Intermediate use only 28-03-2019 View substance registered dossier
4-[2-[4-[benzylmethyl(ethyl)amino]phenyl]vinyl]-1-(2-hydroxyethyl)pyridinium acetate
281-468-5 83950-14-5 Active Full Joint ≥ 10 to < 100 tonnes 19-12-2019 View substance registered dossier
4-[2-piperidinoethoxy]benzoic acid hydrochloride
282-882-9 84449-80-9 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
4-[3-(1-naphthylamino)propyl]morpholine
226-033-2 5235-82-5 Active Full Joint ≥ 10 to < 100 tonnes 26-06-2019 View substance registered dossier
4-[3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol
826-271-2 1402714-41-3 Active Intermediate Joint Intermediate use only 23-07-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Dragon Chemical Europe GmbH Carlsplatz 24 40213 Düsseldorf Germany Germany Active 4-[(3-hydroxypropyl)amino]-3-nitrophenol 406-305-9 92952-81-3 - View substance registered dossier
James Robinson Speciality Ingredients BV Office 12.15 Millenium Tower Radarweg 29 / 12B 1043NX Amsterdam Netherlands Netherlands Active 4-[(3-hydroxypropyl)amino]-3-nitrophenol 406-305-9 92952-81-3 2010; 2016; 2019; 2021 View substance registered dossier
Clariant Produkte (Deutschland) GmbH Am Unisys-Park 1 65843 Sulzbach am Taunus Germany Germany Active 4-[(3-hydroxypropyl)amino]-3-nitrophenol 406-305-9 92952-81-3 - View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Cease Manufacture 4-[(3-hydroxypropyl)amino]-3-nitrophenol 406-305-9 92952-81-3 2019 View substance registered dossier
HFC Prestige Manufacturing Germany GmbH Berliner Allee 65-65a 64295 Darmstadt Germany Germany Active 4-[(3-hydroxypropyl)amino]-3-nitrophenol 406-305-9 92952-81-3 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-[(4,8-disulpho-2-naphthyl)azo]naphthalene-1-diazonium chloride 267-995-3 67969-94-2 2019 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-[(4-amino-5-methoxy-o-tolyl)azo]-5-[(phenylsulphonyl)oxy]naphthalene-2,7-disulphonic acid 204-190-8 117-44-2 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 4-[(4-amino-m-tolyl)(4-imino-3-methylcyclohexa-2,5-dien-1-ylidene)methyl]-o-toluidine monohydrochloride 221-831-7 3248-91-7 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Cease Manufacture 4-[(4-chloro-2-nitrophenyl)azo]-3-hydroxy-N-(2-methylphenyl)naphthalene-2-carboxamide 229-314-8 6471-50-7 2020 View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 4-[(4-ethoxyphenyl)amino]-N,N-dimethyl-3-nitrobenzenesulphonamide 266-648-3 67338-59-4 2017 View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 4-[(4-ethoxyphenyl)amino]-N,N-dimethyl-3-nitrobenzenesulphonamide 266-648-3 67338-59-4 - View substance registered dossier
Archroma Germany GmbH - OR Kasteler Str. 45 65203 Wiesbaden Germany Germany Cease Manufacture 4-[(4-ethoxyphenyl)amino]-N,N-dimethyl-3-nitrobenzenesulphonamide 266-648-3 67338-59-4 2022 View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 4-[(4-ethoxyphenyl)amino]-N,N-dimethyl-3-nitrobenzenesulphonamide 266-648-3 67338-59-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Rolic Technologies B.V. Luchthavenweg 10 5657 EB Eindhoven Netherlands Netherlands Active 4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate - - - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 4-[(5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl)azo]-2,5-dichlorobenzenesulphonic acid 235-473-4 12239-15-5 - View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active 4-[(5-carbamoyl-o-tolyl)azo]-3-hydroxynaphth-2-anilide 240-454-9 16403-84-2 - View substance registered dossier
Sanhu Color Europe BVBA Vlamingstraat 4 8560 Wevelgem Belgium Belgium Active 4-[(5-carbamoyl-o-tolyl)azo]-3-hydroxynaphth-2-anilide 240-454-9 16403-84-2 - View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Cease Manufacture 4-[(6-amino-1-hydroxy-3-sulpho-2-naphthyl)azo]-3-hydroxy-7-nitronaphthalene-1-sulphonic acid 204-203-7 117-69-1 2019 View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile 928-806-6 - - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 4-[(E)-2-nitroethenyl]-1H-indole 634-890-2 49839-99-8 - View substance registered dossier
Penman Consulting bvba 09 Avenue des Arts 10 B-1210 Brussels Belgium Belgium Cease Manufacture 4-[(morpholinothio)thioxomethyl]morpholine 237-335-9 13752-51-7 2021 View substance registered dossier
REACHLaw Ltd( acting as OR for Yasho Industries Limited) Vänrikinkuja 3 JK 21 FI-02600 Espoo Finland Finland Active 4-[(morpholinothio)thioxomethyl]morpholine 237-335-9 13752-51-7 2022 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride 447-990-4 400827-64-7 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-[2-(diethylamino)ethoxy]benzophenone 212-348-2 796-77-0 - View substance registered dossier
Medichem Manufacturing (Malta) Limited HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta Malta Active 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol 700-516-2 93413-62-8 - View substance registered dossier
[Confidential] - - - 4-[2-(methoxymethyl)-3-methyl-1-methylene-but-2-enyl]-1H-tetrazol-5-one 826-908-4 1472631-98-3 - View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 4-[2-[4-(2-benzoxazoleyl)phenyl]vinyl]benzoic acid 225-303-7 4763-79-5 2019 View substance registered dossier
Kemira Oyj Energiakatu 4 P.O.Box 330 FI-00101 HELSINKI Finland Finland Active 4-[2-[4-[benzylmethyl(ethyl)amino]phenyl]vinyl]-1-(2-hydroxyethyl)pyridinium acetate 281-468-5 83950-14-5 2018 View substance registered dossier
Waterside Colours BV Keizersgracht 391 A 1016EJ Amsterdam Amsterdam Netherlands Netherlands Active 4-[2-[4-[benzylmethyl(ethyl)amino]phenyl]vinyl]-1-(2-hydroxyethyl)pyridinium acetate 281-468-5 83950-14-5 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 4-[2-piperidinoethoxy]benzoic acid hydrochloride 282-882-9 84449-80-9 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-[2-piperidinoethoxy]benzoic acid hydrochloride 282-882-9 84449-80-9 2018 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 4-[2-piperidinoethoxy]benzoic acid hydrochloride 282-882-9 84449-80-9 - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-[2-piperidinoethoxy]benzoic acid hydrochloride 282-882-9 84449-80-9 - View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 4-[3-(1-naphthylamino)propyl]morpholine 226-033-2 5235-82-5 - View substance registered dossier
UCM Europe srl Via Monte Rosa, 73 20149 Milano Italy Italy Active 4-[3-(1-naphthylamino)propyl]morpholine 226-033-2 5235-82-5 - View substance registered dossier
Dow Belgium B.V.B.A. Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium Belgium Belgium Active 4-[3-(1-naphthylamino)propyl]morpholine 226-033-2 5235-82-5 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 4-[3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol 826-271-2 1402714-41-3 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-[3-(2,5-Dichlor-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-2-methoxy-6-nitrophenol 826-271-2 1402714-41-3 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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