Registered substances

Registered substances

Registered substances

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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1,2-Ethanediamine, N-{3-(trimethoxysilyl)propyl}-,N-{(ethenylphenyl)methyl}derivate,hydrochlorides
605-620-0 171869-89-9 Active Full Joint ≥ 10 to < 100 tonnes 30-05-2018 View substance registered dossier
1,2-Ethanediamine, N1-(2-aminoethyl)-, 2-hydroxy-2-phenylethyl and stearyl derivs.
807-655-9 1629160-48-0 Active Intermediate Joint Intermediate use only 02-07-2021 View substance registered dossier
1,2-Ethanediamine, N1-(5-methoxy-2-nitrophenyl)-, hydrochloride (1:1)
415-480-0 86419-69-4 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1,2-Ethanediol, reaction products with branched 2-[(4-nonylphenoxy)methyl]oxirane
807-586-4 634602-80-5 Active Full Joint ≥ 1 to < 10 tonnes 30-05-2016 View substance registered dossier
1,2-Ethanediol, reaction products with branched 2-[(4-nonylphenoxy)methyl]oxirane
807-586-4 634602-80-5 Active Intermediate Joint Intermediate use only 06-09-2017 View substance registered dossier
1,2-Ethanediol, reaction products with epichlorohydrin
932-720-4 705265-31-2 Active Intermediate Joint Intermediate use only 07-01-2016 View substance registered dossier
1,2-Heptanediol
855-780-2 3710-31-4 Active Full Joint ≥ 0 to < 10 tonnes 25-04-2022 View substance registered dossier
1,2-Hydrazinedicarboxylic acid, 1-[(6aS,10S,10aS,11aR)-8-(aminocarbonyl)-10-(dimethylamino)-5,6a,7,10,10a,11,11a,12-octahydro-4,6,6a,9-tetrahydroxy-5,7-dioxo-1-naphthacenyl]-, 1,2-bis(phenylmethyl) ester
606-958-1 22229-68-1 Active Intermediate Joint Intermediate use only 13-09-2018 View substance registered dossier
1,2-Naphtoquinonediazide-5-sulfonylchloride (or sulfonic acid) esters with 4,6-bis(1-(4-hydroxyphenyl)-1-methylethyl)-1,3-dihydroxybenzene
433-990-1 - Active Full Joint ≥ 1 to < 10 tonnes 18-12-2019 View substance registered dossier
1,2-O-isopropylidene-α-D-glucofuranose
242-420-9 18549-40-1 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
1,2-Propanediamine, hydrochloride (1:2), (2S)-
606-377-3 19777-66-3 Active Intermediate Joint Intermediate use only 11-01-2021 View substance registered dossier
1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, hydrochloride (1:2), (2S)-
606-947-1 221640-21-7 Active Full Joint ≥ 1 to < 10 tonnes 15-09-2021 View substance registered dossier
1,2-Propanediol, 3-(cyclohexyloxy)-
805-622-3 10305-41-6 Active Full Joint ≥ 0 to < 10 tonnes 07-09-2020 View substance registered dossier
1,2-Propanediol, 3-(hexyloxy)-
600-386-6 10305-38-1 Active Full Joint ≥ 0 to < 10 tonnes 12-03-2021 View substance registered dossier
1,2-Propanediol, 3-chloro-, (2R)-
611-463-9 57090-45-6 Active Intermediate Joint Intermediate use only 07-02-2017 View substance registered dossier
1,2-Propanediol, monocarbamate
614-981-3 69493-47-6 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester, (2R)-
682-153-9 166170-15-6 Active Intermediate Joint Intermediate use only 12-06-2018 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 3-[(dimethylamino)methylene]-4-oxo-, bis(1,1-dimethylethyl) ester, [S-(E)]-
942-146-6 166410-06-6 Active Intermediate Joint Intermediate use only 27-03-2017 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 4-(methoxymethyl)-, 1-(1,1-dimethylethyl) ester, (2S,4S)-
807-416-9 1378388-16-9 Active Intermediate Joint Intermediate use only 20-04-2018 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)-
604-011-7 13726-69-7 Active Intermediate Joint Intermediate use only 12-02-2019 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1,2-bis(1,1-dimethylethyl) ester, (2S)-
807-593-2 166410-05-5 Active Intermediate Joint Intermediate use only 20-09-2016 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-dimethylethyl) ester, (2S)-
617-556-0 84348-37-8 Active Intermediate Joint Intermediate use only 18-03-2020 View substance registered dossier
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)-
480-250-9 144978-12-1 Active Intermediate Joint Intermediate use only 28-05-2020 View substance registered dossier
1,2:5,6-di-O-isopropylidene-α-D-glucofuranose
209-486-0 582-52-5 Active Intermediate Joint Intermediate use only 26-06-2020 View substance registered dossier
1,3'-Bipyridinium, 5'-[[4-[[4-[(1',2'-dihydro-6'-hydroxy-3,4'-dimethyl-2'-oxo[1,3'-bipyridinium]-5'-yl)azo]benzoyl]amino]phenyl]azo]-1',2'-dihydro-6'-hydroxy-3,4'-dimethyl-2'-oxo-, salt with 2-hydroxypropanoic acid (1:2)
278-130-4 75214-63-0 Active Full Joint ≥ 1 to < 10 tonnes 17-11-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid 1,2-Ethanediamine, N-{3-(trimethoxysilyl)propyl}-,N-{(ethenylphenyl)methyl}derivate,hydrochlorides 605-620-0 171869-89-9 - View substance registered dossier
Dow Silicones Belgium SPRL OR-1 rue Jules Bordet Parc industriel C 7180 Seneffe Belgium Belgium Active 1,2-Ethanediamine, N-{3-(trimethoxysilyl)propyl}-,N-{(ethenylphenyl)methyl}derivate,hydrochlorides 605-620-0 171869-89-9 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1,2-Ethanediamine, N-{3-(trimethoxysilyl)propyl}-,N-{(ethenylphenyl)methyl}derivate,hydrochlorides 605-620-0 171869-89-9 - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active 1,2-Ethanediamine, N1-(2-aminoethyl)-, 2-hydroxy-2-phenylethyl and stearyl derivs. 807-655-9 1629160-48-0 2015; 2021 View substance registered dossier
Výzkumný ústav organických syntéz a.s. č.p. 296 533 54 Rybitví Czech Republic Czech Republic Active 1,2-Ethanediamine, N1-(2-aminoethyl)-, 2-hydroxy-2-phenylethyl and stearyl derivs. 807-655-9 1629160-48-0 - View substance registered dossier
- - - - 1,2-Ethanediamine, N1-(5-methoxy-2-nitrophenyl)-, hydrochloride (1:1) 415-480-0 86419-69-4 - View substance registered dossier
BASF Espanola S.L. Calle Can Ràbia, n. 3-5 8017 Barcelona Spain Spain Active 1,2-Ethanediol, reaction products with branched 2-[(4-nonylphenoxy)methyl]oxirane 807-586-4 634602-80-5 - View substance registered dossier
Dow Belgium B.V.B.A. Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium Belgium Belgium Active 1,2-Ethanediol, reaction products with branched 2-[(4-nonylphenoxy)methyl]oxirane 807-586-4 634602-80-5 - View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 1,2-Ethanediol, reaction products with branched 2-[(4-nonylphenoxy)methyl]oxirane 807-586-4 634602-80-5 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 1,2-Ethanediol, reaction products with epichlorohydrin 932-720-4 705265-31-2 2016 View substance registered dossier
Symrise Granada, S.A.U. Crta. Armilla Km 2, 5 18100 Armilla Granada Spain Spain Active 1,2-Heptanediol 855-780-2 3710-31-4 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 1,2-Heptanediol 855-780-2 3710-31-4 2021 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 1,2-Hydrazinedicarboxylic acid, 1-[(6aS,10S,10aS,11aR)-8-(aminocarbonyl)-10-(dimethylamino)-5,6a,7,10,10a,11,11a,12-octahydro-4,6,6a,9-tetrahydroxy-5,7-dioxo-1-naphthacenyl]-, 1,2-bis(phenylmethyl) ester 606-958-1 22229-68-1 - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active 1,2-Hydrazinedicarboxylic acid, 1-[(6aS,10S,10aS,11aR)-8-(aminocarbonyl)-10-(dimethylamino)-5,6a,7,10,10a,11,11a,12-octahydro-4,6,6a,9-tetrahydroxy-5,7-dioxo-1-naphthacenyl]-, 1,2-bis(phenylmethyl) ester 606-958-1 22229-68-1 - View substance registered dossier
JSR Micro n.v. Technologielaan 8 3001 Leuven Belgium Belgium Active 1,2-Naphtoquinonediazide-5-sulfonylchloride (or sulfonic acid) esters with 4,6-bis(1-(4-hydroxyphenyl)-1-methylethyl)-1,3-dihydroxybenzene 433-990-1 - 2012; 2019 View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active 1,2-O-isopropylidene-α-D-glucofuranose 242-420-9 18549-40-1 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active 1,2-O-isopropylidene-α-D-glucofuranose 242-420-9 18549-40-1 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1,2-O-isopropylidene-α-D-glucofuranose 242-420-9 18549-40-1 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 1,2-Propanediamine, hydrochloride (1:2), (2S)- 606-377-3 19777-66-3 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active 1,2-Propanediamine, hydrochloride (1:2), (2S)- 606-377-3 19777-66-3 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active 1,2-Propanediamine, hydrochloride (1:2), (2S)- 606-377-3 19777-66-3 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, hydrochloride (1:2), (2S)- 606-947-1 221640-21-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1,2-Propanediamine, N1-(2-aminoethyl)-3-(4-ethoxyphenyl)-, hydrochloride (1:2), (2S)- 606-947-1 221640-21-7 2021 View substance registered dossier
ADEKA Europe GmbH Berliner Allee 22 40212 Düsseldorf Germany Germany Active 1,2-Propanediol, 3-(cyclohexyloxy)- 805-622-3 10305-41-6 2014; 2020 View substance registered dossier
ADEKA Europe GmbH Berliner Allee 22 40212 Düsseldorf Germany Germany Active 1,2-Propanediol, 3-(hexyloxy)- 600-386-6 10305-38-1 2014; 2021 View substance registered dossier
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland Ireland Active 1,2-Propanediol, 3-chloro-, (2R)- 611-463-9 57090-45-6 - View substance registered dossier
BASF Coatings GmbH Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany Germany Active 1,2-Propanediol, monocarbamate 614-981-3 69493-47-6 - View substance registered dossier
Schirm GmbH Geschwister-Scholl-Strasse 127 D-39218 Schönebeck Germany Germany Active 1,2-Propanediol, monocarbamate 614-981-3 69493-47-6 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 2-methyl-, 1-(1,1-dimethylethyl) ester, (2R)- 682-153-9 166170-15-6 2018 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 3-[(dimethylamino)methylene]-4-oxo-, bis(1,1-dimethylethyl) ester, [S-(E)]- 942-146-6 166410-06-6 2017 View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active 1,2-Pyrrolidinedicarboxylic acid, 4-(methoxymethyl)-, 1-(1,1-dimethylethyl) ester, (2S,4S)- 807-416-9 1378388-16-9 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 1,2-Pyrrolidinedicarboxylic acid, 4-(methoxymethyl)-, 1-(1,1-dimethylethyl) ester, (2S,4S)- 807-416-9 1378388-16-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 4-(methoxymethyl)-, 1-(1,1-dimethylethyl) ester, (2S,4S)- 807-416-9 1378388-16-9 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)- 604-011-7 13726-69-7 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)- 604-011-7 13726-69-7 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1,2-bis(1,1-dimethylethyl) ester, (2S)- 807-593-2 166410-05-5 2016 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1,2-bis(1,1-dimethylethyl) ester, (2S)- 807-593-2 166410-05-5 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-dimethylethyl) ester, (2S)- 617-556-0 84348-37-8 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1,2-Pyrrolidinedicarboxylic acid, 4-oxo-, 1-(1,1-dimethylethyl) ester, (2S)- 617-556-0 84348-37-8 2020 View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active 1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)- 480-250-9 144978-12-1 2020 View substance registered dossier
Flamma S.p.a.- OR Via Bedeschi, 22 24040 Chignolo D'Isola Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)- 480-250-9 144978-12-1 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)- 480-250-9 144978-12-1 - View substance registered dossier
NetSun EU B.V. Blaak 40, Floor 5 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture 1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)- 480-250-9 144978-12-1 2018 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) 2-ethyl ester, (2S)- 480-250-9 144978-12-1 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 209-486-0 582-52-5 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 209-486-0 582-52-5 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active 1,3'-Bipyridinium, 5'-[[4-[[4-[(1',2'-dihydro-6'-hydroxy-3,4'-dimethyl-2'-oxo[1,3'-bipyridinium]-5'-yl)azo]benzoyl]amino]phenyl]azo]-1',2'-dihydro-6'-hydroxy-3,4'-dimethyl-2'-oxo-, salt with 2-hydroxypropanoic acid (1:2) 278-130-4 75214-63-0 2020 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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