Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Edetic acid
200-449-4 60-00-4 Active Full Joint ≥ 1 000 tonnes 15-03-2022 View substance registered dossier
4-aminoazobenzene
200-453-6 60-09-3 Active Intermediate Individual Intermediate use only 09-12-2015 View substance registered dossier
2-phenylethanol
200-456-2 60-12-8 Active Full Joint ≥ 1 000 to < 10 000 tonnes 13-07-2021 View substance registered dossier
2-phenylethanol
200-456-2 60-12-8 No longer Valid Full Individual No longer valid 04-10-2012 View substance registered dossier
2-phenylethanol
200-456-2 60-12-8 Active Intermediate Joint Intermediate use only 30-03-2021 View substance registered dossier
Tyrosine
200-460-4 60-18-4 Active Full Joint ≥ 1 to < 10 tonnes 31-08-2021 View substance registered dossier
4-hydroxyphenethylammonium chloride
200-462-5 60-19-5 Active Intermediate Joint Intermediate use only 21-06-2018 View substance registered dossier
Mercaptamine
200-463-0 60-23-1 Active Full Joint ≥ 0 to < 10 tonnes 17-05-2018 View substance registered dossier
2-mercaptoethanol
200-464-6 60-24-2 Active Full Joint ≥ 1 000 to < 10 000 tonnes 11-09-2020 View substance registered dossier
2-imino-1-methylimidazolidin-4-one
200-466-7 60-27-5 Active Full Joint ≥ 1 to < 10 tonnes 26-07-2019 View substance registered dossier
Diethyl ether
200-467-2 60-29-7 Active Full Joint ≥ 1 000 to < 10 000 tonnes 17-11-2021 View substance registered dossier
Aminocaproic acid
200-469-3 60-32-2 Active Full Joint ≥ 1 tonnes 17-04-2019 View substance registered dossier
Methylhydrazine
200-471-4 60-34-4 Active Full Joint ≥ 10 to < 100 tonnes 16-02-2018 View substance registered dossier
Methylhydrazine
200-471-4 60-34-4 Cease Manufacture Intermediate Individual Cease manufacture 15-11-2012 View substance registered dossier
Methylhydrazine
200-471-4 60-34-4 Active Intermediate Joint Intermediate use only 11-01-2017 View substance registered dossier
Methylhydrazine
200-471-4 60-34-4 Active Intermediate Individual Intermediate use only 22-03-2011 View substance registered dossier
Acetamide
200-473-5 60-35-5 Active Full Joint ≥ 10 to < 100 tonnes 26-04-2018 View substance registered dossier
Tetracycline
200-481-9 60-54-8 Active Intermediate Joint Intermediate use only 10-05-2016 View substance registered dossier
Thiamazole
200-482-4 60-56-0 Active Intermediate Joint Intermediate use only 15-12-2016 View substance registered dossier
Phenazone
200-486-6 60-80-0 Active Intermediate Joint Intermediate use only 13-09-2010 View substance registered dossier
2'-(β-D-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone
200-487-1 60-81-1 Active Full Joint ≥ 1 to < 10 tonnes 13-11-2017 View substance registered dossier
Promethazine
200-489-2 60-87-7 Active Intermediate Joint Intermediate use only 28-05-2018 View substance registered dossier
Quinine dihydrochloride
200-493-4 60-93-5 Active Intermediate Joint Intermediate use only 06-03-2015 View substance registered dossier
Acepromazine
200-496-0 61-00-7 Active Intermediate Individual Intermediate use only 27-01-2015 View substance registered dossier
Adenosine phosphate
200-500-0 61-19-8 Active Full Joint ≥ 1 to < 10 tonnes 28-02-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Nouryon Functional Chemicals B.V. Velperweg 76 6824 BM Arnhem Netherlands Netherlands Active Edetic acid 200-449-4 60-00-4 2017 View substance registered dossier
DOW BENELUX B.V. - OR1 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active Edetic acid 200-449-4 60-00-4 2016 View substance registered dossier
Only representative (No publishable name) - - Active Edetic acid 200-449-4 60-00-4 2012; 2015; 2022 View substance registered dossier
Corteva Agriscience France S.A.S. Immeuble Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancourt France France Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
SA DABEER C/ Pasaje Arrahona 18 2º 08210 Barbera del Vallés Spain Spain Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
PURE FISHING Inc 219 Routede Brignais 69563 Saint Genis Laval France France France Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
DOW AGROSCIENCES B.V. (BE) Rue Montoyer 25, 1000 Brussels Belgium Belgium Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED (Weifang Binhai Petro-chem. Co., Ltd) Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Edetic acid 200-449-4 60-00-4 2016 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Edetic acid 200-449-4 60-00-4 2021 View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture Edetic acid 200-449-4 60-00-4 2019 View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture Edetic acid 200-449-4 60-00-4 2021 View substance registered dossier
DEKRA Assurance Services GmbH OR07 Handwerkstr. 15 70565 Stuttgart Germany Germany Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
solvadis specialties gmbh Königsbergerstr. 1 60487 Frankfurt am Main Germany Germany Active Edetic acid 200-449-4 60-00-4 2020 View substance registered dossier
Nouryon Functional Chemicals AB Stenunge Allé 3 - SE-444 85 Stenungsund - Sweden Sweden Active Edetic acid 200-449-4 60-00-4 2021 View substance registered dossier
knoell Germany – OR – A1 Konrad-Zuse-Ring 25 68163 Mannheim Germany Germany Active Edetic acid 200-449-4 60-00-4 2020 View substance registered dossier
Merck S.L.U. Calle Maria de Molina 28006 Madrid Spain Spain Active Edetic acid 200-449-4 60-00-4 2020 View substance registered dossier
B-Lands Consulting (811232-9) World Trade Center, 5 Place Robert Schuman - BP 1510 38025 Grenoble France France France Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Edetic acid 200-449-4 60-00-4 2011; 2014; 2021 View substance registered dossier
Pure Fishing Netherlands B.V Tinstraat 3 2nd Floor 4823 AA Breda NOORD-BRABANT Netherlands Netherlands Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
CIBA VISION GmbH (OR CVCA) Industriering 1 63868 Großwallstadt Bavaria Germany Germany Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
Valagro S.p.A. Zona Industriale 66041 Atessa CH Italy Italy Active Edetic acid 200-449-4 60-00-4 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Cease Manufacture Edetic acid 200-449-4 60-00-4 2020 View substance registered dossier
[Confidential] - - - Edetic acid 200-449-4 60-00-4 - View substance registered dossier
BASF Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 4-aminoazobenzene 200-453-6 60-09-3 2015 View substance registered dossier
FIRMENICH GRASSE SAS OR 8 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
Luxcontrol S.A. (OR66) 1, Avenue des Terres Rouges 4331 Esch/Alzette Luxembourg Luxembourg Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
Koopman International B.V. Distelweg 88 1031 HH Amsterdam Netherlands Netherlands Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 2-phenylethanol 200-456-2 60-12-8 2018 View substance registered dossier
Givaudan France SAS - OR2 55, Rue de la voie des Bans 95102 Argenteuil Cedex France France Cease Manufacture 2-phenylethanol 200-456-2 60-12-8 2016 View substance registered dossier
Symrise H17 Mühlenfeldstr. 1 37603 Holzminden Germany Germany Active 2-phenylethanol 200-456-2 60-12-8 2020 View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Cease Manufacture 2-phenylethanol 200-456-2 60-12-8 2016 View substance registered dossier
REACHLaw Ltd. Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
IFF NL 1 Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Cease Manufacture 2-phenylethanol 200-456-2 60-12-8 2019 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active 2-phenylethanol 200-456-2 60-12-8 2021 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 2-phenylethanol 200-456-2 60-12-8 2014 View substance registered dossier
Intertek Deutschland GmbH IEFC* Stangenstr.1 70771 Leinfelden-Echterdingen Germany Germany Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
BorsodChem Zrt. - OR Bolyai ter 1. H-3700 Kazincbarcika Hungary Hungary Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland Ireland Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
Robertet 37 Avenue Sidi Brahim 06130 Grasse France France Active 2-phenylethanol 200-456-2 60-12-8 - View substance registered dossier
Merck Schuchardt OHG Eduard-Buchner-Str. 85662 Hohenbrunn Germany Germany Active 2-phenylethanol 200-456-2 60-12-8 2021 View substance registered dossier
Koopman International B.V. Distelweg 88 1031 HH Amsterdam Netherlands Netherlands No longer Valid 2-phenylethanol 200-456-2 60-12-8 2017 View substance registered dossier
Knoell NL_OR_060 Agro Business Park 75 6708 PV Wageningen Netherlands Netherlands Active 2-phenylethanol 200-456-2 60-12-8 2021 View substance registered dossier
Dr. Paul Lohmann GmbH & Co. KGaA Hauptstraße 2 31860 Emmerthal Germany Germany Active Tyrosine 200-460-4 60-18-4 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active Tyrosine 200-460-4 60-18-4 - View substance registered dossier
SYNTHEXIM 1 Quai d'Amérique 62 100 calais France France Active 4-hydroxyphenethylammonium chloride 200-462-5 60-19-5 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active 4-hydroxyphenethylammonium chloride 200-462-5 60-19-5 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active Mercaptamine 200-463-0 60-23-1 - View substance registered dossier
Resindion S.r.l. Via Roma, 55 20082 Binasco Milano Italy Italy Cease Manufacture Mercaptamine 200-463-0 60-23-1 2018 View substance registered dossier
Chevron Phillips Chemicals International NV Airport Plaza, Stockholm Building, Da Vincilaan 19 B-1831 DIEGEM Belgium Belgium Active 2-mercaptoethanol 200-464-6 60-24-2 2011; 2012; 2014; 2016; 2017; 2018 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 2-mercaptoethanol 200-464-6 60-24-2 2011; 2012; 2017; 2018 View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active 2-mercaptoethanol 200-464-6 60-24-2 - View substance registered dossier
PPG Europe B.V. in its legal capacity as Only Representative of PRC DeSoto International Inc. - OR5 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active 2-mercaptoethanol 200-464-6 60-24-2 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active 2-mercaptoethanol 200-464-6 60-24-2 2020 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active 2-imino-1-methylimidazolidin-4-one 200-466-7 60-27-5 2019 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany No longer Valid 2-imino-1-methylimidazolidin-4-one 200-466-7 60-27-5 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid Diethyl ether 200-467-2 60-29-7 2021 View substance registered dossier
Ineos Solvents Germany GmbH Roemerstr. 733 47443 Moers Germany Germany Active Diethyl ether 200-467-2 60-29-7 2010; 2012; 2015; 2018; 2019; 2020; 2021 View substance registered dossier
Scharlab S.L. Gato Pérez, 33 08181 Sentmenat Barcelona Spain Spain Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Nammo Vihtavuori Oy Ruutitehtaantie 80 41330 Vihtavuori Finland Finland Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
POLYNT S.p.A. via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy Italy Cease Manufacture Diethyl ether 200-467-2 60-29-7 2021 View substance registered dossier
SIGMA-ALDRICH CHIMIE SARL 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France France Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
INEOS Chemicals Grangemouth Ltd (Enterprises) DeerLeap Chapel Lane SO43 7FG Lyndhurst Hampshire United Kingdom United Kingdom No longer Valid Diethyl ether 200-467-2 60-29-7 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Diethyl ether 200-467-2 60-29-7 2021 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Mesko S.A Legionow 122 26-111 Skarzysko-Kamienna Poland Poland Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Str. 40 30926 Seelze Deutschland Germany Germany Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active Diethyl ether 200-467-2 60-29-7 - View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid Aminocaproic acid 200-469-3 60-32-2 2021 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Aminocaproic acid 200-469-3 60-32-2 - View substance registered dossier
Aquafil S.p.A. Via Linfano, 9 38062 Arco (TN) Italy Italy Active Aminocaproic acid 200-469-3 60-32-2 - View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr.13 40210 Duessldorf Germany Germany Active Methylhydrazine 200-471-4 60-34-4 2013; 2018 View substance registered dossier
GHC Gerling, Holz & Co. Handels GmbH Ruhrstraße 113 22761 Hamburg Hamburg Germany Germany Active Methylhydrazine 200-471-4 60-34-4 - View substance registered dossier
ArianeGroup 11 quai André CITROEN 75015 PARIS France France Active Methylhydrazine 200-471-4 60-34-4 2018 View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Cease Manufacture Methylhydrazine 200-471-4 60-34-4 2019 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active Methylhydrazine 200-471-4 60-34-4 2012; 2017 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Methylhydrazine 200-471-4 60-34-4 - View substance registered dossier
Chr. Olesen ChemPharm GmbH Gustav-Becker-Strasse 20B 21218 Seevetal Germany Germany Active Acetamide 200-473-5 60-35-5 - View substance registered dossier
SKW Stickstoffwerke Piesteritz GmbH Möllensdorfer Straße 13 06886 Lutherstadt Wittenberg Germany Germany Active Acetamide 200-473-5 60-35-5 2016 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active Acetamide 200-473-5 60-35-5 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Tetracycline 200-481-9 60-54-8 2016 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active Thiamazole 200-482-4 60-56-0 - View substance registered dossier
[Confidential] - - - Phenazone 200-486-6 60-80-0 - View substance registered dossier
[Confidential] - - - 2'-(β-D-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone 200-487-1 60-81-1 - View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Promethazine 200-489-2 60-87-7 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Promethazine 200-489-2 60-87-7 - View substance registered dossier
Buchler GmbH Harxbütteler Straße 3 D-38110 Braunschweig Germany Germany Active Quinine dihydrochloride 200-493-4 60-93-5 - View substance registered dossier
Sigma-Aldrich Ireland Ltd Vale Road . Arklow Co. Wicklow Ireland Ireland Active Acepromazine 200-496-0 61-00-7 2015 View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active Adenosine phosphate 200-500-0 61-19-8 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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