Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-iodo-6-(trifluoromethyl)aniline
860-133-2 1207315-39-6 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
4-(1,4-dioxa-spiro[4.5]dec-8-yl)-cyclohexanone
423-860-2 56309-94-5 Active Intermediate Joint Intermediate use only 10-12-2019 View substance registered dossier
4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium)hemisulphate
926-418-1 - Active Intermediate Individual Intermediate use only 09-05-2018 View substance registered dossier
4-(1H-pyrazol-1-yl)piperidine hydrochloride
691-327-3 690261-87-1 Active Intermediate Joint Intermediate use only 22-05-2018 View substance registered dossier
4-(2,2,3,3-tetrafluoropropyl)-morpholin
815-272-3 343331-58-8 Active Intermediate Joint Intermediate use only 07-04-2021 View substance registered dossier
4-(2,6,6-trimethyl-2-cyclohexen-1-yl)butan-2-one
250-657-4 31499-72-6 Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide)
GLIMEPIRID-SULFONAMID; GLIMEPIRIDE SULFONAMIDE
411-850-0 119018-29-0 Active Intermediate Joint Intermediate use only 26-09-2019 View substance registered dossier
4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide)
GLIMEPIRID-SULFONAMID; GLIMEPIRIDE SULFONAMIDE
411-850-0 119018-29-0 Active Intermediate Individual Intermediate use only 13-02-2018 View substance registered dossier
4-(2-aminoethyl)benzenesulphonamide
252-501-0 35303-76-5 Active Intermediate Joint Intermediate use only 09-02-2022 View substance registered dossier
4-(2-aminoethyl)phenol
200-115-8 51-67-2 Active Intermediate Joint Intermediate use only 05-01-2016 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Menadiona SL Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain Spain Active 4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-iodo-6-(trifluoromethyl)aniline 860-133-2 1207315-39-6 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(1,4-dioxa-spiro[4.5]dec-8-yl)-cyclohexanone 423-860-2 56309-94-5 2011; 2013; 2019 View substance registered dossier
[Confidential] - - - 4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium)hemisulphate 926-418-1 - - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 4-(1H-pyrazol-1-yl)piperidine hydrochloride 691-327-3 690261-87-1 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active 4-(2,2,3,3-tetrafluoropropyl)-morpholin 815-272-3 343331-58-8 - View substance registered dossier
Central Glass Germany GmbH Kantstrasse 2 33790 Halle/Westf. Nordrhein Westfalen Germany Germany Active 4-(2,2,3,3-tetrafluoropropyl)-morpholin 815-272-3 343331-58-8 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 4-(2,6,6-trimethyl-2-cyclohexen-1-yl)butan-2-one 250-657-4 31499-72-6 - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide) 411-850-0 119018-29-0 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active 4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide) 411-850-0 119018-29-0 2019 View substance registered dossier
[Confidential] - - - 4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide) 411-850-0 119018-29-0 - View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active 4-(2-((3-ethyl-4-methyl-2-oxo-pyrrolin-1-yl)carboxamido)ethyl)benzenesulfonamide) 411-850-0 119018-29-0 2010; 2012; 2018 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 2022 View substance registered dossier
Midas Pharma GmbH Rheinstrasse 49 55218 Ingelheim Germany Germany Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 - View substance registered dossier
KINSY, S.L. Avda. Europa s/n Parque Industrial de Alhama 30840 Alhama de Murcia Murcia Spain Spain Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 - View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 - View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 2014 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active 4-(2-aminoethyl)benzenesulphonamide 252-501-0 35303-76-5 2021; 2022 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-(2-aminoethyl)phenol 200-115-8 51-67-2 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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