Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(R)-2-amino-3-phenylpropanol
226-086-1 5267-64-1 Active Intermediate Joint Intermediate use only 29-11-2018 View substance registered dossier
(R)-2-aminobutan-1-ol
227-476-4 5856-63-3 Active Intermediate Joint Intermediate use only 19-07-2019 View substance registered dossier
(R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate
942-402-7 - Active Intermediate Joint Intermediate use only 24-09-2021 View substance registered dossier
(R)-3,7-dimethyloct-6-en-1-ol
214-250-5 1117-61-9 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
(R)-3,7-dimethyloct-6-enal
219-194-5 2385-77-5 Active Intermediate Joint Intermediate use only 13-02-2019 View substance registered dossier
(R)-3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate
843-372-7 856408-80-5 Active Intermediate Joint Intermediate use only 23-09-2019 View substance registered dossier
(R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole
921-685-0 - Active Intermediate Joint Intermediate use only 05-04-2018 View substance registered dossier
(R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
691-120-8 486460-00-8 Active Intermediate Joint Intermediate use only 31-05-2022 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Active Intermediate Joint Intermediate use only 25-04-2018 View substance registered dossier
(R)-3-cyclohexyl-2-hydroxypropionic acid
812-501-9 156469-00-0 Active Intermediate Joint Intermediate use only 01-06-2018 View substance registered dossier
(R)-3-phenyllactic acid
230-803-3 7326-19-4 Active Intermediate Joint Intermediate use only 17-05-2018 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate
949-784-4 - Active Intermediate Individual Intermediate use only 25-03-2019 View substance registered dossier
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-760-2 219861-18-4 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
920-209-9 - Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(R)-5-(2-Phenylsulphonylethenyl)-3(N-Methylpyrrolidine-2-ylmethyl)-1-H-indole methane sulphonic acid)
880-102-7 1196663-24-7 Active Intermediate Joint Intermediate use only 22-02-2022 View substance registered dossier
(R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indol oxalate
846-313-3 1196663-29-2 Active Intermediate Joint Intermediate use only 02-12-2019 View substance registered dossier
(R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one
224-957-0 4573-50-6 Active Intermediate Individual Intermediate use only 11-06-2019 View substance registered dossier
(R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
264-133-8 63422-71-9 Active Intermediate Joint Intermediate use only 08-05-2017 View substance registered dossier
(R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid
264-133-8 63422-71-9 Active Intermediate Individual Intermediate use only 21-08-2013 View substance registered dossier
(R)-cyclohex-3-enecarboxylic acid
634-674-8 5709-98-8 Active Intermediate Joint Intermediate use only 11-09-2017 View substance registered dossier
(R)-methyl(α-methylphenethyl)ammonium [R-(R*,R*)]-hydrogen tartrate
298-036-7 93777-08-3 Active Intermediate Joint Intermediate use only 06-10-2017 View substance registered dossier
(R)-quinuclidin-3-ol
246-857-6 25333-42-0 Active Intermediate Joint Intermediate use only 11-04-2022 View substance registered dossier
(R)-α-aminocyclohexa-1,4-diene-1-acetic acid
247-999-1 26774-88-9 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
(R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate
PHENETHYLAMMONIUM SALT OF FOSFOMYCIN
418-570-8 25383-07-7 Active Intermediate Joint Intermediate use only 22-05-2020 View substance registered dossier
(R)-β-aminophenethyl alcohol
260-287-5 56613-80-0 Active Intermediate Joint Intermediate use only 18-01-2021 View substance registered dossier
(R*,S*)-(±)-α-[1-(methylamino)ethyl]benzyl alcohol hydrochloride
205-153-9 134-71-4 Active Intermediate Joint Intermediate use only 30-07-2015 View substance registered dossier
(R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol
278-718-0 77542-06-4 Active Intermediate Individual Intermediate use only 26-03-2019 View substance registered dossier
(R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate
445-750-3 839705-03-2 Active Intermediate Individual Intermediate use only 16-04-2013 View substance registered dossier
(R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one
421-830-3 49805-30-3 Active Intermediate Joint Intermediate use only 28-09-2020 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-780-1 103146-25-4 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate
430-790-6 658080-64-9 Active Intermediate Joint Intermediate use only 05-05-2015 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate
430-790-6 658080-64-9 Active Intermediate Joint Intermediate use only 01-05-2018 View substance registered dossier
(RS)-2-methylbutyryl chloride
260-787-3 57526-28-0 Active Intermediate Joint Intermediate use only 25-07-2017 View substance registered dossier
(S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt
918-890-2 - Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(S) 2-(Benzyloxycarbonylamino) 4-(neopentyloxysulfonyl)butyl thioacetate
873-888-8 1370348-26-7 Active Intermediate Joint Intermediate use only 27-09-2021 View substance registered dossier
(S)- 3-[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxy]-pyrrolidine hydrochloride
948-439-5 2114341-27-2 Active Intermediate Joint Intermediate use only 15-12-2020 View substance registered dossier
(S)- 3[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxyl]-pyrrolidine -1-carboxylic tert butyl ether
861-843-5 1383793-75-6 Active Intermediate Joint Intermediate use only 16-12-2020 View substance registered dossier
(S)-(+)-1-methoxy-2-propylamine
700-220-3 99636-32-5 Active Intermediate Individual Intermediate use only 30-09-2010 View substance registered dossier
(S)-(-)-1-(1-Naphthyl)ethylamine (2R,3R)-2,3-dihydroxybutanedioic salt
600-817-8 1073145-07-9 Active Intermediate Joint Intermediate use only 22-01-2018 View substance registered dossier
(S)-1,2-epoxypropane
240-241-0 16088-62-3 Active Intermediate Joint Intermediate use only 16-12-2010 View substance registered dossier
(S)-1-(3-Fluoro-propyl)-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-pyrrolidine
950-570-8 2114341-28-3 Active Intermediate Joint Intermediate use only 19-11-2020 View substance registered dossier
(S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline
265-250-7 64838-55-7 Active Intermediate Joint Intermediate use only 22-03-2019 View substance registered dossier
(S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid
- - Active Intermediate Joint Intermediate use only 30-03-2022 View substance registered dossier
(S)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde
245-846-3 23727-15-3 Active Intermediate Joint Intermediate use only 07-12-2021 View substance registered dossier
(S)-2,2,4-trimethylpyrrolidine hydrochloride
943-629-4 1897428-40-8 Active Intermediate Joint Intermediate use only 16-07-2018 View substance registered dossier
(S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide
UK-88,861-04
421-810-4 194602-27-2 Active Intermediate Joint Intermediate use only 24-09-2010 View substance registered dossier
(S)-2,3-dihydro-1H-indole-2-carboxylic acid
[S]-2-INDOLINE CARBOXYLIC ACID
410-860-2 79815-20-6 Active Intermediate Joint Intermediate use only 17-03-2014 View substance registered dossier
(S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester
873-085-2 74844-93-2 Active Intermediate Joint Intermediate use only 01-06-2022 View substance registered dossier
(S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid
951-381-3 - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 2019 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - 2018; 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-3,7-dimethyloct-6-en-1-ol 214-250-5 1117-61-9 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-3,7-dimethyloct-6-enal 219-194-5 2385-77-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (R)-3,7-dimethyloct-6-enal 219-194-5 2385-77-5 2013; 2018; 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (R)-3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate 843-372-7 856408-80-5 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Covance Clinical Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2018 View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-cyclohexyl-2-hydroxypropionic acid 812-501-9 156469-00-0 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-phenyllactic acid 230-803-3 7326-19-4 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate 949-784-4 - - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 2019 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate 920-209-9 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (R)-5-(2-Phenylsulphonylethenyl)-3(N-Methylpyrrolidine-2-ylmethyl)-1-H-indole methane sulphonic acid) 880-102-7 1196663-24-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (R)-5-Bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indol oxalate 846-313-3 1196663-29-2 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-6-(isopropyl)-3-methylcyclohex-2-en-1-one 224-957-0 4573-50-6 - View substance registered dossier
REACHLaw Ltd Vänrikinkuja 3 JK 21 02600 Espoo Finland Finland Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (R)-[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetic acid 264-133-8 63422-71-9 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-cyclohex-3-enecarboxylic acid 634-674-8 5709-98-8 - View substance registered dossier
[Confidential] - - - (R)-methyl(α-methylphenethyl)ammonium [R-(R*,R*)]-hydrogen tartrate 298-036-7 93777-08-3 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 2017 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active (R)-quinuclidin-3-ol 246-857-6 25333-42-0 - View substance registered dossier
Centrient Pharmaceuticals Spain S.A. Calle Ripollès, no. 2 08130 Santa Perpètua de Mogoda (Barcelona) Spain Spain Active (R)-α-aminocyclohexa-1,4-diene-1-acetic acid 247-999-1 26774-88-9 - View substance registered dossier
LABIANA PHARMACEUTICALS S.L. Carrer Casanova, 27-31 08757 Corbera de Llobregat Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
Siemsgluss Ibérica, S.A. Pol. Ind. Sant Antoni, parcela 6, nave 2 08620 Sant Vicenç dels Horts Barcelona Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 2011; 2016; 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 2011; 2020 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active (R)-α-phenylethylammonium (-)-(1R, 2S)-(1,2-epoxypropyl)phosphonate monohydrate 418-570-8 25383-07-7 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (R)-β-aminophenethyl alcohol 260-287-5 56613-80-0 2020; 2021 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (R*,S*)-(±)-α-[1-(methylamino)ethyl]benzyl alcohol hydrochloride 205-153-9 134-71-4 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (R*,S*)-(±)-α-[4-[2-(dimethylamino)ethoxy]phenyl]-β-ethyl-α-phenylphenethyl alcohol 278-718-0 77542-06-4 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R,S)-1-[2-amino-1(4-methoxyphenyl)ethyl]cyclohexanol acetate 445-750-3 839705-03-2 2013 View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland Ireland Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (R,S)-2-azabicyclo[2.2.1]hept-5-en-3-one 421-830-3 49805-30-3 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-780-1 103146-25-4 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-780-1 103146-25-4 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. - - Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate 430-790-6 658080-64-9 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate 430-790-6 658080-64-9 2015 View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemisulfate 430-790-6 658080-64-9 2015; 2018 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (RS)-2-methylbutyryl chloride 260-787-3 57526-28-0 - View substance registered dossier
Bábolna Bioenvironmental Centre Ltd. Szállás u. 6. H-1107 Budapest Hungary Hungary Active (S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt 918-890-2 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S) 2-(Benzyloxycarbonylamino) 4-(neopentyloxysulfonyl)butyl thioacetate 873-888-8 1370348-26-7 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S)- 3-[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxy]-pyrrolidine hydrochloride 948-439-5 2114341-27-2 2020 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S)- 3[4-(4,4,5,5-tetramethyl-[1,3,2] dioxaborolan-2-yl)-phenoxyl]-pyrrolidine -1-carboxylic tert butyl ether 861-843-5 1383793-75-6 2020 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (S)-(+)-1-methoxy-2-propylamine 700-220-3 99636-32-5 2010 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (S)-(-)-1-(1-Naphthyl)ethylamine (2R,3R)-2,3-dihydroxybutanedioic salt 600-817-8 1073145-07-9 - View substance registered dossier
Labcorp Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (S)-1,2-epoxypropane 240-241-0 16088-62-3 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (S)-1-(3-Fluoro-propyl)-3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-pyrrolidine 950-570-8 2114341-28-3 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline 265-250-7 64838-55-7 2018 View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline 265-250-7 64838-55-7 2019 View substance registered dossier
L.C.M. TRADING SPA via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy Italy Active (S)-1-[3-(acetylthio)-2-methyl-1-oxopropyl]-L-proline 265-250-7 64838-55-7 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (S)-1’- (tert-butyl)-2’-oxo-1’,2’,5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3’-pyrrolo[2,3-b]pyridine]-3-carboxylic acid - - - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (S)-2,2,3-trimethylcyclopent-3-ene-1-acetaldehyde 245-846-3 23727-15-3 2021 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (S)-2,2,4-trimethylpyrrolidine hydrochloride 943-629-4 1897428-40-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 2010 View substance registered dossier
Zach System ZI La Croix Cadeau 49242 Avrillé France France Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-2,2-diphenyl-2(3-pyrrolidinyl)acetonitrile hydrobromide 421-810-4 194602-27-2 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 2013; 2014 View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (S)-2,3-dihydro-1H-indole-2-carboxylic acid 410-860-2 79815-20-6 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 873-085-2 74844-93-2 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (S)-2,5-Dihydro-pyrrole-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 873-085-2 74844-93-2 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid 951-381-3 - 2021 View substance registered dossier
[Confidential] - - - (S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid - - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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