Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Reaction mass of 604-916-7 and (4R,4aS,5aR,12aS)- 4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-nitro-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide sulfate (1:2),
935-744-3 - Active Intermediate Joint Intermediate use only 03-10-2019 View substance registered dossier
Reaction mass of 9-icosyl-9-phosphabicyclo[3.3.1]nonane and 9-icosyl-9-phosphabicyclo[4.2.1]nonane
915-206-4 - Cease Manufacture Intermediate Individual Cease manufacture 24-04-2013 View substance registered dossier
Reaction mass of [(4-hydroxybutyl)imino]dihexane-6,1-diyl bis(2-hexyldecanoate) and 6-oxohexyl 2-hexyldecanoate
953-347-3 - Cease Manufacture Intermediate Individual Cease manufacture 17-11-2020 View substance registered dossier
Reaction mass of [1-{[(1S,2R)-2-(diethylcarbamoyl)-2-phenylcyclopropyl]methyl}-3,5,7-triaza-1-azoniatricyclo[3.3.1]decane chloride] and [1-{[(1R,2S)-2-(diethylcarbamoyl)-2-phenylcyclopropyl]methyl}-3,5,7-triaza-1-azoniatricyclo[3.3.1]decane chloride]
947-546-4 - Active Intermediate Joint Intermediate use only 08-05-2018 View substance registered dossier
Reaction mass of [3-(2-hydroxyethoxy)-3-oxopropyl]arylphosphinic acid and 3-(hydroxyarylphosphinyl)propanoic acid and ethane-1,2-diol
- - Active Intermediate Individual Intermediate use only 18-05-2011 View substance registered dossier
Reaction mass of [3-methyl-1-(2,2,3-trimethylcyclopent-3-en-1-yl)cyclohex-3-en-1-yl]methanol and rel-{(1R)-4-methyl-1-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohex-3-en-1-yl}methanol and rel-{(1R)-4-methyl-1-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohex-3-en-1-yl}methanol
946-070-4 - Active Intermediate Joint Intermediate use only 18-09-2017 View substance registered dossier
Reaction mass of [R-(E)]-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)pent-1-en-3-one and 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)pent-1-en-3-one and 3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one
907-708-7 - Active Intermediate Joint Intermediate use only 20-05-2019 View substance registered dossier
reaction mass of a-D-erythro-Pentofuranose,2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate and β-D-erythro-Pentofuranose,2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate
700-722-2 - Cease Manufacture Intermediate Individual Cease manufacture 20-02-2013 View substance registered dossier
Reaction mass of acetic acid and ethane peroxoic acid
902-388-5 - Active Intermediate Individual Intermediate use only 16-02-2017 View substance registered dossier
Reaction mass of acetonitrile and phenyl vinyl sulphone
903-661-1 - Active Intermediate Individual Intermediate use only 05-04-2018 View substance registered dossier
Reaction mass of alkylpolyglycol carboxylic acid and alkylpolyglycol carboxylic acid alkylester
- - Active Intermediate Individual Intermediate use only 07-09-2011 View substance registered dossier
Reaction mass of aluminium fluoride and aluminium oxide and chromium (III) oxide and nickel dichloride
909-803-9 - Cease Manufacture Intermediate Individual Cease manufacture 12-11-2010 View substance registered dossier
Reaction mass of aluminium oxide and divanadium pentaoxide and molybdenum trioxide
910-374-5 - Active Intermediate Individual Intermediate use only 29-11-2019 View substance registered dossier
Reaction mass of aluminium oxide and vanadium dioxide
931-787-7 - Active Intermediate Individual Intermediate use only 22-10-2019 View substance registered dossier
Reaction mass of ammonium 4-amino-3-nitrobenzenesulfonate and sodium 4-amino-3-nitrobenzenesulfonate
700-384-6 82324-60-5 No longer Valid Intermediate Individual No longer valid 31-10-2012 View substance registered dossier
Reaction mass of ammonium 4-amino-3-nitrobenzenesulfonate and sodium 4-amino-3-nitrobenzenesulfonate
700-384-6 82324-60-5 Active Intermediate Individual Intermediate use only 25-10-2017 View substance registered dossier
Reaction mass of ammonium chloride and sodium chlorate and sodium chloride
913-623-6 - Cease Manufacture Intermediate Individual Cease manufacture 29-05-2013 View substance registered dossier
Reaction mass of ammonium hydrogensulphite, ammonium sulphite and sulphur dioxide
932-162-1 - Active Intermediate Individual Intermediate use only 24-11-2010 View substance registered dossier
Reaction mass of ammonium sulphite and ammonium hydrogensulphite
914-977-4 - Active Intermediate Joint Intermediate use only 16-11-2010 View substance registered dossier
Reaction mass of Benzenediazonium, 3-carboxy-4-hydroxy- and Benzenediazonium, 3-carboxy-2-hydroxy-
900-111-2 - Active Intermediate Joint Intermediate use only 06-03-2018 View substance registered dossier
Reaction mass of Benzeneethanol, 2-chloro-α-(1-chlorocyclopropyl)-α-(chloromethyl)- and Oxirane, 2-(1-chlorcyclopropyl)-2-[(2-chlorphenyl)methyl]-
929-889-1 - Active Intermediate Individual Intermediate use only 01-12-2016 View substance registered dossier
Reaction mass of bis(2-ethylhexyl) fumarate and bis(2-ethylhexyl) maleate
907-868-8 - Active Intermediate Individual Intermediate use only 25-11-2020 View substance registered dossier
Reaction mass of bis(hydroxyammonium) sulfate and diammonium sulfate
914-294-1 - Active Intermediate Joint Intermediate use only 12-02-2013 View substance registered dossier
Reaction mass of bis(hydroxyammonium) sulfate and diammonium sulfate
914-294-1 - Active Intermediate Individual Intermediate use only 30-09-2010 View substance registered dossier
Reaction mass of butyraldehyde and isobutyraldehyde
904-298-1 - Active Intermediate Individual Intermediate use only 23-11-2010 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active Reaction mass of 604-916-7 and (4R,4aS,5aR,12aS)- 4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-nitro-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide sulfate (1:2), 935-744-3 - 2011; 2013; 2019 View substance registered dossier
Shell Chemicals Europe B.V. Weena 70 3012 CM Rotterdam Netherlands Netherlands Cease Manufacture Reaction mass of 9-icosyl-9-phosphabicyclo[3.3.1]nonane and 9-icosyl-9-phosphabicyclo[4.2.1]nonane 915-206-4 - 2020 View substance registered dossier
Croda EU B.V. (OR8) Buurtje 1 2802 BE Gouda Netherlands Netherlands Cease Manufacture Reaction mass of [(4-hydroxybutyl)imino]dihexane-6,1-diyl bis(2-hexyldecanoate) and 6-oxohexyl 2-hexyldecanoate 953-347-3 - 2022 View substance registered dossier
JSC Grindeks Krustpils street 53 LV-1057 Riga Latvia Latvia Active Reaction mass of [1-{[(1S,2R)-2-(diethylcarbamoyl)-2-phenylcyclopropyl]methyl}-3,5,7-triaza-1-azoniatricyclo[3.3.1]decane chloride] and [1-{[(1R,2S)-2-(diethylcarbamoyl)-2-phenylcyclopropyl]methyl}-3,5,7-triaza-1-azoniatricyclo[3.3.1]decane chloride] 947-546-4 - - View substance registered dossier
[Confidential] - - - Reaction mass of [3-(2-hydroxyethoxy)-3-oxopropyl]arylphosphinic acid and 3-(hydroxyarylphosphinyl)propanoic acid and ethane-1,2-diol - - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active Reaction mass of [3-methyl-1-(2,2,3-trimethylcyclopent-3-en-1-yl)cyclohex-3-en-1-yl]methanol and rel-{(1R)-4-methyl-1-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohex-3-en-1-yl}methanol and rel-{(1R)-4-methyl-1-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohex-3-en-1-yl}methanol 946-070-4 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active Reaction mass of [R-(E)]-1-(2,6,6-trimethyl-2-cyclohexen-1-yl)pent-1-en-3-one and 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)pent-1-en-3-one and 3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one 907-708-7 - - View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture reaction mass of a-D-erythro-Pentofuranose,2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate and β-D-erythro-Pentofuranose,2-deoxy-2,2-difluoro-, 3,5-dibenzoate 1-methanesulfonate 700-722-2 - 2015 View substance registered dossier
Intertek Deutschland GmbH 48 Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany Germany Active Reaction mass of acetic acid and ethane peroxoic acid 902-388-5 - 2012; 2017 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active Reaction mass of acetonitrile and phenyl vinyl sulphone 903-661-1 - - View substance registered dossier
Kao Chemicals GmbH Kupferstrasse 1 46446 Emmerich Northrhine-Westfalia Germany Germany Active Reaction mass of alkylpolyglycol carboxylic acid and alkylpolyglycol carboxylic acid alkylester - - 2010; 2011 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Cease Manufacture Reaction mass of aluminium fluoride and aluminium oxide and chromium (III) oxide and nickel dichloride 909-803-9 - 2019 View substance registered dossier
Treibacher Industrie AG Auer-von-Welsbach-Straße 1 9330 Althofen Carinthia Austria Austria Active Reaction mass of aluminium oxide and divanadium pentaoxide and molybdenum trioxide 910-374-5 - 2010; 2011; 2019 View substance registered dossier
Treibacher Industrie AG Auer-von-Welsbach-Straße 1 9330 Althofen Carinthia Austria Austria Active Reaction mass of aluminium oxide and vanadium dioxide 931-787-7 - 2011; 2019 View substance registered dossier
BASF plc Earl Road, P O Box 4 SK8 6QG Cheadle Hulme Cheshire United Kingdom United Kingdom No longer Valid Reaction mass of ammonium 4-amino-3-nitrobenzenesulfonate and sodium 4-amino-3-nitrobenzenesulfonate 700-384-6 82324-60-5 2021 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active Reaction mass of ammonium 4-amino-3-nitrobenzenesulfonate and sodium 4-amino-3-nitrobenzenesulfonate 700-384-6 82324-60-5 - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Cease Manufacture Reaction mass of ammonium chloride and sodium chlorate and sodium chloride 913-623-6 - 2020 View substance registered dossier
TEMBEC TARTAS SAS 1154, Avenue du Général Leclerc 40400 TARTAS France France Active Reaction mass of ammonium hydrogensulphite, ammonium sulphite and sulphur dioxide 932-162-1 - - View substance registered dossier
Savon Sellu Oy Sorsasalo FI-70420 KUOPIO FINLAND Finland Finland Active Reaction mass of ammonium sulphite and ammonium hydrogensulphite 914-977-4 - - View substance registered dossier
UBE Corporation Europe, S.A.U. Poligono Industrial El Serrallo, s/n 12100 Castellón Spain Spain Active Reaction mass of ammonium sulphite and ammonium hydrogensulphite 914-977-4 - - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Reaction mass of Benzenediazonium, 3-carboxy-4-hydroxy- and Benzenediazonium, 3-carboxy-2-hydroxy- 900-111-2 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Reaction mass of Benzeneethanol, 2-chloro-α-(1-chlorocyclopropyl)-α-(chloromethyl)- and Oxirane, 2-(1-chlorcyclopropyl)-2-[(2-chlorphenyl)methyl]- 929-889-1 - 2010; 2016 View substance registered dossier
Solvay Solutions Italia S.p.A. Via Milano, 78/80 20021 Ospiate di Bollate (Mi) Italy Italy Active Reaction mass of bis(2-ethylhexyl) fumarate and bis(2-ethylhexyl) maleate 907-868-8 - - View substance registered dossier
UBE Corporation Europe, S.A.U. Poligono Industrial El Serrallo, s/n 12100 Castellón Spain Spain Active Reaction mass of bis(hydroxyammonium) sulfate and diammonium sulfate 914-294-1 - 2013 View substance registered dossier
Grupa Azoty S.A. ul. Kwiatkowskiego 8 33-101 Tarnow Poland Poland Active Reaction mass of bis(hydroxyammonium) sulfate and diammonium sulfate 914-294-1 - - View substance registered dossier
OQ Chemicals Produktion GmbH & Co. KG Otto-Roelen-Str. 3 46147 Oberhausen NRW Germany Germany Active Reaction mass of butyraldehyde and isobutyraldehyde 904-298-1 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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