Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
251-561-5 33522-95-1 Active Intermediate Joint Intermediate use only 31-03-2022 View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
257-924-4 52446-24-9 Active Intermediate Joint Intermediate use only 16-03-2017 View substance registered dossier
(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol
207-385-6 467-04-9 Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
208-085-8 508-54-3 No longer Valid Intermediate Joint No longer valid 15-03-2018 View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one
282-186-5 84116-46-1 No longer Valid Intermediate Joint No longer valid 12-07-2019 View substance registered dossier
(5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride
245-549-9 23277-43-2 Active Intermediate Joint Intermediate use only 19-06-2017 View substance registered dossier
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate
2691; CARTASOL BRILLANT SCHARLACH K-2GL KONZ.; CARTASOL BRILLANTSCHARLACH K-2GL FLÜSSIG (ZUBEREITUNG); CARTASOL BRILLANTSCHARLACH K-2GL GRANULAT (ZUBEREITUNG); CARTASOL BRILLIANT SCARLET K-2GL; CARTASOL BRILLIANT SCARLET K-2GL CONC.
402-060-7 108225-03-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride
842-055-0 2356133-42-9 Active Intermediate Individual Intermediate use only 21-08-2019 View substance registered dossier
(6-aminohexyl)carbamic acid
205-581-6 143-06-6 Active Full Joint ≥ 100 to < 1 000 tonnes 02-10-2018 View substance registered dossier
(6-Bromo-2-pyridinyl)(4-methylphenyl)methanone
618-079-0 87848-95-1 No longer Valid Full Individual No longer valid 25-10-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride 257-924-4 52446-24-9 - View substance registered dossier
HH Compliance The Rubicon Centre CIT Campus , Bishopstown T12 Y275 Cork Co Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
Alcaliber S.A. Ventalomar 1 45007 Toledo Toledo Spain Spain Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
HH Compliance Ltd Rubicon Building, CIT Campus Bishopstown None Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one 208-085-8 508-54-3 2021 View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one 282-186-5 84116-46-1 2021 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride 245-549-9 23277-43-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Norwegian competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Cease Manufacture (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 2016 View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Cease Manufacture (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Portuguese competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Archroma UK, Ltd 1 Bartholomew Lane EC2N 2AX London United Kingdom United Kingdom No longer Valid (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 2021 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active (6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride 842-055-0 2356133-42-9 - View substance registered dossier
[Confidential] - - - (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
IB CHEM S.R.L. VIA E. FERMI 21E 72100 BRINDISI Italy Italy Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 2018 View substance registered dossier
C.S.B. GmbH Duesseldorfer Str.113 47809 Krefeld Germany Germany Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
Unimatec Chemicals Europe Im Technologiepark 1 69469 Weinheim Germany Germany Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland Ireland Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
W. L. Gore & Associates GmbH Hermann-Oberth-Strasse 22 85640 Putzbrunn Germany Germany Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (6-Bromo-2-pyridinyl)(4-methylphenyl)methanone 618-079-0 87848-95-1 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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