Registered substances

Registered substances

Registered substances

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(10aS)-methyl 10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate
607-239-5 23495-64-9 Active Full Joint ≥ 1 000 to < 10 000 tonnes 28-05-2018 View substance registered dossier
(10E)-oxacycloheptadec-10-en-2-one
814-308-5 63286-42-0 Active Full Joint ≥ 10 to < 100 tonnes 18-04-2019 View substance registered dossier
(11-oxo-6,11-dihydro-dibenzo[b,e]oxepin-2-yl)-acetic acid butyl ester
853-457-0 60548-14-3 Active Intermediate Joint Intermediate use only 15-05-2020 View substance registered dossier
(17alpha)-3-ethoxy-19-norpregna-3,5-dien-20-yn-17-ol
619-217-2 96487-85-3 Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
(17ß)-3-Hydroxyestra-1,3,5(10)-trien-17-yl acetate
605-722-5 1743-60-8 Active Intermediate Joint Intermediate use only 27-04-2018 View substance registered dossier
(17α)-17-hydroxy-3-oxoandrost-4-ene-17-carbonitrile
278-780-9 77881-13-1 Active Intermediate Joint Intermediate use only 22-10-2012 View substance registered dossier
(17β)-13-Ethyl-17-ethynyl-3-oxogon-4-en-17-yl acetate
604-013-8 13732-69-9 Active Intermediate Joint Intermediate use only 20-03-2018 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene
- - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol
- - Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
(1E)-1-chloro-3,3,3-trifluoroprop-1-ene
700-486-0 102687-65-0 Active Full Joint ≥ 1 000 to < 10 000 tonnes 27-02-2020 View substance registered dossier
(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one
616-668-7 79200-56-9 Active Intermediate Joint Intermediate use only 10-01-2018 View substance registered dossier
(1R)-1-(4-methylphenyl)ethylamine (2S)-5-oxopyrrolidine-2-carboxylate
814-654-7 122170-65-4 Active Intermediate Joint Intermediate use only 29-03-2018 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Joint ≥ 1 000 tonnes 21-12-2021 View substance registered dossier
(1R)-1-Naphthylethylamine Hydrochloride
617-358-4 82572-04-1 Active Intermediate Joint Intermediate use only 02-05-2018 View substance registered dossier
(1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride
700-425-8 521284-22-0 Active Full Joint Tonnage data confidential 30-03-2016 View substance registered dossier
(1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol
252-744-2 35836-73-8 Active Full Joint ≥ 10 to < 100 tonnes 18-05-2021 View substance registered dossier
(1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid
252-817-9 35963-20-3 Active Intermediate Joint Intermediate use only 07-01-2020 View substance registered dossier
(1R)cyclohex-3-enecarboxylic acid (1S)-1-phenylethylamine
814-700-6 67976-81-2 Active Intermediate Joint Intermediate use only 03-10-2017 View substance registered dossier
(1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride
609-015-2 3464-71-9 Active Intermediate Joint Intermediate use only 12-03-2018 View substance registered dossier
(1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate
607-316-3 240806-31-9 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile
608-856-2 33300-19-5 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,2R)-1,2-Cyclohexanedimethanol
692-053-7 65376-05-8 Active Intermediate Joint Intermediate use only 24-10-2018 View substance registered dossier
(1R,2R)-1-Amino-2-(difluoromethyl)-N-(1-methylcyclopropylsulfonyl)cyclopropanecarboxamide hydrochloride
943-460-6 1360828-80-3 Active Intermediate Joint Intermediate use only 16-06-2020 View substance registered dossier
(1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid
609-759-8 39961-95-0 Active Intermediate Joint Intermediate use only 29-01-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (10aS)-methyl 10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate 607-239-5 23495-64-9 - View substance registered dossier
IFF NL 1 Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active (10E)-oxacycloheptadec-10-en-2-one 814-308-5 63286-42-0 - View substance registered dossier
FIRMENICH GRASSE SAS OR 5 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (10E)-oxacycloheptadec-10-en-2-one 814-308-5 63286-42-0 2019 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (10E)-oxacycloheptadec-10-en-2-one 814-308-5 63286-42-0 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active (10E)-oxacycloheptadec-10-en-2-one 814-308-5 63286-42-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (11-oxo-6,11-dihydro-dibenzo[b,e]oxepin-2-yl)-acetic acid butyl ester 853-457-0 60548-14-3 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active (17alpha)-3-ethoxy-19-norpregna-3,5-dien-20-yn-17-ol 619-217-2 96487-85-3 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (17ß)-3-Hydroxyestra-1,3,5(10)-trien-17-yl acetate 605-722-5 1743-60-8 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (17α)-17-hydroxy-3-oxoandrost-4-ene-17-carbonitrile 278-780-9 77881-13-1 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (17β)-13-Ethyl-17-ethynyl-3-oxogon-4-en-17-yl acetate 604-013-8 13732-69-9 - View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}-17-[(trimethylsilyl)substitued]estratetraene - - - View substance registered dossier
[Confidential] - - - (17β)-3-{[alkyl(dimethyl)silyl]substituted}estratetraen-17-ol - - - View substance registered dossier
Honeywell Belgium NV OR-1000 Gaston Geenslaan 14 - 2nd Floor Arenberg Wetenschapspark B-3001 Heverlee Belgium Belgium Active (1E)-1-chloro-3,3,3-trifluoroprop-1-ene 700-486-0 102687-65-0 2013; 2014; 2015; 2016 View substance registered dossier
Honeywell Fluorine Products Europe BV Stationsplein Zuid-West 961 1117 CE Schiphol-Oost Netherlands Netherlands Active (1E)-1-chloro-3,3,3-trifluoroprop-1-ene 700-486-0 102687-65-0 2016; 2020 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active (1E)-1-chloro-3,3,3-trifluoroprop-1-ene 700-486-0 102687-65-0 2017 View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one 616-668-7 79200-56-9 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)-1-(4-methylphenyl)ethylamine (2S)-5-oxopyrrolidine-2-carboxylate 814-654-7 122170-65-4 - View substance registered dossier
Chemservice GmbH - (X88M) Herrnsheimer Hauptstrasse 1b 67550 Worms Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2013; 2018 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
[Confidential] - - - (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
Milliken Europe BV (importer) Ham 18-24 9000 Gent Belgium Belgium Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
Peram Handelsgesellschaft mbH Dorotheenstraße 48 22301 Hamburg Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2014; 2020; 2021 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)-1-Naphthylethylamine Hydrochloride 617-358-4 82572-04-1 - View substance registered dossier
[Confidential] - - - (1R)-2-[5-(2-halo-3-methoxyphenyl)-3-[2-halo-6-(trihalomethyl)benzyl]- 4-alkyl-2,6-dioxoheterocyclyl]-1-phenylethanaminium salicylate - - - View substance registered dossier
[Confidential] - - - (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride 700-425-8 521284-22-0 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol 252-744-2 35836-73-8 2018 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol 252-744-2 35836-73-8 2017; 2021 View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 2018 View substance registered dossier
PORTA s.r.o. Zelený pruh 99 14002 Praha 4 Czech Republic Czech Republic Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 2018 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)cyclohex-3-enecarboxylic acid (1S)-1-phenylethylamine 814-700-6 67976-81-2 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride 609-015-2 3464-71-9 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate 607-316-3 240806-31-9 2018 View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile 608-856-2 33300-19-5 2018 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (1R,2R)-1,2-Cyclohexanedimethanol 692-053-7 65376-05-8 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (1R,2R)-1-Amino-2-(difluoromethyl)-N-(1-methylcyclopropylsulfonyl)cyclopropanecarboxamide hydrochloride 943-460-6 1360828-80-3 2020 View substance registered dossier
AbbVie Ireland NL B.V. Manorhamilton Road none Sligo Ireland Ireland Active (1R,2R)-1-Amino-2-(difluoromethyl)-N-(1-methylcyclopropylsulfonyl)cyclopropanecarboxamide hydrochloride 943-460-6 1360828-80-3 - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (1R,2R)-1-Amino-2-(difluoromethyl)-N-(1-methylcyclopropylsulfonyl)cyclopropanecarboxamide hydrochloride 943-460-6 1360828-80-3 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid 609-759-8 39961-95-0 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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