Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
Formaldehyde 200-001-8 50-00-0 Active Intermediate Joint Intermediate use only 07-07-2020 View substance registered dossier
Guanidinium chloride
200-002-3 50-01-1 Active Full Joint ≥ 100 to < 1 000 tonnes 12-05-2021 View substance registered dossier
Dexamethasone
200-003-9 50-02-2 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
Hydrocortisone 21-acetate
200-004-4 50-03-3 Active Intermediate Joint Intermediate use only 12-12-2012 View substance registered dossier
Cortisone 21-acetate
200-006-5 50-04-4 Active Intermediate Joint Intermediate use only 20-11-2017 View substance registered dossier
Phenobarbital
200-007-0 50-06-6 Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
Lactic acid
200-018-0 50-21-5 Active Full Joint ≥ 100 to < 1 000 tonnes 04-04-2022 View substance registered dossier
Hydrocortisone
200-020-1 50-23-7 Active Intermediate Joint Intermediate use only 06-09-2021 View substance registered dossier
Prednisolone
200-021-7 50-24-8 Active Full Joint ≥ 10 to < 100 tonnes 17-03-2020 View substance registered dossier
Estradiol
200-023-8 50-28-2 Active Full Joint ≥ 1 to < 10 tonnes 03-09-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
SNF SA ZAC de Milieux 42163 Andrézieux France France Active Formaldehyde 200-001-8 50-00-0 - View substance registered dossier
Arcerion GmbH Gabrielenstr. 15 80636 München Germany Germany Active Formaldehyde 200-001-8 50-00-0 2020 View substance registered dossier
SNF S.A.S. ZAC de Milieux 42163 Andrézieux France France Active Formaldehyde 200-001-8 50-00-0 - View substance registered dossier
J.A.Moeller GmbH & Co.KG Müllenhofweg 44A 22607 Hamburg Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
SIGMA-ALDRICH CHIMIE SARL 80 Rue de Luzais BP 701 38297 Saint Quentin Fallavier France France Active Guanidinium chloride 200-002-3 50-01-1 2020 View substance registered dossier
LGC Genomics Ltd Units 1-2 Trident Industrial Estate Pindar Road EN11 0WZ Hoddesdon United Kingdom United Kingdom No longer Valid Guanidinium chloride 200-002-3 50-01-1 2021 View substance registered dossier
AppliChem GmbH Ottoweg 4 64291 Darmstadt Hessen Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
HH Compliance The Rubicon Centre, CIT Campus, Bishopstown, Cork Ireland Ireland Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
Central Glass Germany GmbH Kantstrasse 2 33790 Halle/Westf. Nordrhein Westfalen Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
AVANTOR PERFORMANCE MATERIALS POLAND SPÓŁKA AKCYJNA Sowińskiego 11 44-101 Gliwice Silesia Poland Poland Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 2020 View substance registered dossier
Sigma-Aldrich Company Limited The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom United Kingdom No longer Valid Guanidinium chloride 200-002-3 50-01-1 2021 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 2014; 2015; 2019; 2021 View substance registered dossier
HH Compliance Ltd Rubicon Centre C.I.T. Campus T12 Y275 Bishopstown Cork Ireland Ireland Active Guanidinium chloride 200-002-3 50-01-1 2019 View substance registered dossier
MACHEREY-NAGEL GmbH & Co. KG Valencienner Str. 11 52355 Dueren NRW Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 2020 View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active Guanidinium chloride 200-002-3 50-01-1 2020 View substance registered dossier
Thermo Fisher Scientific Baltics UAB V.A.Graiciuno 8 LT-02241 Vilnius Lithuania Lithuania Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
Acros Organics bv Janssen Pharmaceuticalaan 3a B-2440 Geel Belgium Belgium Active Guanidinium chloride 200-002-3 50-01-1 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active Dexamethasone 200-003-9 50-02-2 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active Dexamethasone 200-003-9 50-02-2 2021; 2022 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture Hydrocortisone 21-acetate 200-004-4 50-03-3 2012 View substance registered dossier
[Confidential] - - - Hydrocortisone 21-acetate 200-004-4 50-03-3 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Cortisone 21-acetate 200-006-5 50-04-4 - View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active Phenobarbital 200-007-0 50-06-6 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Lactic acid 200-018-0 50-21-5 2021 View substance registered dossier
Chementors Oy Smart Chemistry Park Raisionkaari 55 21200 Raisio Finland Finland Active Lactic acid 200-018-0 50-21-5 2021 View substance registered dossier
Galactic Place d'Escanaffles 23 7760 Escanaffles Belgium Belgium Active Lactic acid 200-018-0 50-21-5 2022 View substance registered dossier
Purac Biochem bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active Lactic acid 200-018-0 50-21-5 2018; 2021; 2022 View substance registered dossier
BIOFER SpA Via Tommaso da Cazzaniga 9/6 20121 Milano Milano Italy Italy Active Hydrocortisone 200-020-1 50-23-7 2012; 2013; 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Cease Manufacture Hydrocortisone 200-020-1 50-23-7 2015 View substance registered dossier
VALDEPHARM Parc Industriel d'Incarville CS10606 27106 Val de Reuil France France Active Hydrocortisone 200-020-1 50-23-7 2012 View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active Hydrocortisone 200-020-1 50-23-7 - View substance registered dossier
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy Italy Active Hydrocortisone 200-020-1 50-23-7 2013 View substance registered dossier
RSI ChemRep Europe Ltd (P001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active Hydrocortisone 200-020-1 50-23-7 2021 View substance registered dossier
[Confidential] - - - Hydrocortisone 200-020-1 50-23-7 - View substance registered dossier
Steroid SpA Viale Spagna 156 20093 Cologno Monzese Milano Italy Italy Active Prednisolone 200-021-7 50-24-8 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active Prednisolone 200-021-7 50-24-8 - View substance registered dossier
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy Italy Active Prednisolone 200-021-7 50-24-8 2013 View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active Prednisolone 200-021-7 50-24-8 - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active Prednisolone 200-021-7 50-24-8 2011 View substance registered dossier
[Confidential] - - - Prednisolone 200-021-7 50-24-8 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active Prednisolone 200-021-7 50-24-8 - View substance registered dossier
VALDEPHARM Parc Industriel d'Incarville CS10606 27106 Val de Reuil France France Active Estradiol 200-023-8 50-28-2 2012; 2018 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active Estradiol 200-023-8 50-28-2 2012; 2017 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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