Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Butanedioic acid, 2,2'-dithiobis-
415-850-1 3384-95-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
A mixture of: (3R)-[1S-(1α, 2α, 6 β-((2S)-2-methyl-1-oxo-butoxy)-8aγ)hexahydro-2,6-dimethyl-1-naphthalene]-3,5-dihydroxyheptanoic acid; inert biomass from aspergillus terreus
LOVASTATIN FREE ACID
415-840-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
F-BASE
415-830-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
[R-(R*,S*)]-[[2-methyl-1-(1-oxopropoxy)propoxy]-(4-phenylbutyl)phosphinyl] acetic acid, (-)-cinchonidine (1:1) salt
SQ 28,796
415-820-8 137590-32-0 Active NONS Joint Tonnage data confidential 27-10-2017 View substance registered dossier
SAVINYL ROUGE E-3BS
415-810-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
A mixture of isomers of: dodecylammonium (octachloro)(sulfonato)phtalocyaninatocuprate(II)
106 VERTE
415-800-9 - Active NONS Joint Tonnage data confidential 25-06-2009 View substance registered dossier
TPS 15
415-790-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Zinc cysteate dihydrate
CB 619
415-780-1 129770-96-3 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2,7,11-trimethyl-13-(2,6,6-trimethylcyclohex-1-en-1-yl)tridecahexaen-2,4,6,8,10,12-al
C25-ALDEHYD
415-770-7 1638-05-7 Active NONS Individual Tonnage data confidential 09-01-2012 View substance registered dossier
REACTIVE SCARLET TZ 3949
415-760-2 - Active NONS Joint Tonnage data confidential 25-02-2014 View substance registered dossier
3-(cis-1-propenyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-PACA
415-750-8 106447-44-3 Active NONS Joint Tonnage data confidential 29-10-2012 View substance registered dossier
3-(cis-1-propenyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
7-PACA
415-750-8 106447-44-3 Active Intermediate Joint Intermediate use only 29-09-2016 View substance registered dossier
NJ-300
415-740-3 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
3-cyano-N-(1,1-dimethylethyl)androsta-3,5-diene-17-β-carboxamide
SB 206396
415-730-9 151338-11-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
NK 280
415-720-4 209971-72-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
Potassium N-(4-fluorophenyl)glycinate
POTASSIUM N-(4-FLUOROPHENYL)GLYCINATE
415-710-1 184637-63-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
Potassium 2,5-dichlorobenzoate
POTASSIUM 2,5-DICHLOROBENZOATE
415-700-5 184637-62-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl 2-carboxy-3-(2-thienyl)propionate
SB-201999
415-680-8 143468-96-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate
GR138766X
415-670-3 78850-37-0 Cease Manufacture Intermediate Joint Cease manufacture 20-01-2010 View substance registered dossier
Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate
GR138766X
415-670-3 78850-37-0 No longer Valid NONS Joint No longer valid 10-11-2008 View substance registered dossier
1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride
DOXAZOSIN 4; DOXAZOSIN STEP 4
415-660-9 70918-74-0 Active NONS Joint Tonnage data confidential 22-03-2011 View substance registered dossier
Reaction mass of Pentaerythritol bis (2-ethylhexanoate) bis (3,5,5-trimethylhexanoate) and Pentaerythritol tris (2-ethylhexanoate) 3,5,5-trimethylhexanoate and Pentaerythritol 2-ethylhexanoate tris (3,5,5-trimethylhexanoate) and Pentaeryhthritol tetrakis(2-ethylhexanoate) and Pentaerythritol tetrakis (3,5,5-trimethylhexanoate)
415-650-4 153965-54-9 Active Full Joint ≥ 10 to < 100 tonnes 03-06-2020 View substance registered dossier
Reaction mass of Pentaerythritol bis (2-ethylhexanoate) bis (3,5,5-trimethylhexanoate) and Pentaerythritol tris (2-ethylhexanoate) 3,5,5-trimethylhexanoate and Pentaerythritol 2-ethylhexanoate tris (3,5,5-trimethylhexanoate) and Pentaeryhthritol tetrakis(2-ethylhexanoate) and Pentaerythritol tetrakis (3,5,5-trimethylhexanoate)
415-650-4 153965-54-9 No longer Valid NONS Individual No longer valid 13-06-2012 View substance registered dossier
METHYLSECODION
415-640-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
5-ethoxy-1,3-dimethyl-1,3-dihydroindol-2-one
ESERINETHER
415-630-5 131057-63-1 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Butanedioic acid, 2,2'-dithiobis- 415-850-1 3384-95-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active A mixture of: (3R)-[1S-(1α, 2α, 6 β-((2S)-2-methyl-1-oxo-butoxy)-8aγ)hexahydro-2,6-dimethyl-1-naphthalene]-3,5-dihydroxyheptanoic acid; inert biomass from aspergillus terreus 415-840-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active F-BASE 415-830-2 - - View substance registered dossier
L.C.M. TRADING SPA via Mazzini 33 20099 Sesto San Giovanni Lombardia Italy Italy Active [R-(R*,S*)]-[[2-methyl-1-(1-oxopropoxy)propoxy]-(4-phenylbutyl)phosphinyl] acetic acid, (-)-cinchonidine (1:1) salt 415-820-8 137590-32-0 2013; 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active [R-(R*,S*)]-[[2-methyl-1-(1-oxopropoxy)propoxy]-(4-phenylbutyl)phosphinyl] acetic acid, (-)-cinchonidine (1:1) salt 415-820-8 137590-32-0 - View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active [R-(R*,S*)]-[[2-methyl-1-(1-oxopropoxy)propoxy]-(4-phenylbutyl)phosphinyl] acetic acid, (-)-cinchonidine (1:1) salt 415-820-8 137590-32-0 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active SAVINYL ROUGE E-3BS 415-810-3 - - View substance registered dossier
- - - - A mixture of isomers of: dodecylammonium (octachloro)(sulfonato)phtalocyaninatocuprate(II) 415-800-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active TPS 15 415-790-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active Zinc cysteate dihydrate 415-780-1 129770-96-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active Zinc cysteate dihydrate 415-780-1 129770-96-3 - View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Active 2,7,11-trimethyl-13-(2,6,6-trimethylcyclohex-1-en-1-yl)tridecahexaen-2,4,6,8,10,12-al 415-770-7 1638-05-7 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active REACTIVE SCARLET TZ 3949 415-760-2 - - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active REACTIVE SCARLET TZ 3949 415-760-2 - 2010; 2014 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture 3-(cis-1-propenyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 415-750-8 106447-44-3 2021 View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active 3-(cis-1-propenyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 415-750-8 106447-44-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 3-(cis-1-propenyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 415-750-8 106447-44-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active NJ-300 415-740-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 3-cyano-N-(1,1-dimethylethyl)androsta-3,5-diene-17-β-carboxamide 415-730-9 151338-11-3 - View substance registered dossier
- - - - NK 280 415-720-4 209971-72-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active NK 280 415-720-4 209971-72-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Potassium N-(4-fluorophenyl)glycinate 415-710-1 184637-63-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Potassium 2,5-dichlorobenzoate 415-700-5 184637-62-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Ethyl 2-carboxy-3-(2-thienyl)propionate 415-680-8 143468-96-6 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate 415-670-3 78850-37-0 2019 View substance registered dossier
SmithKline Beecham plc 980 Great West Road TW8 9GS Brentford Middlesex United Kingdom United Kingdom No longer Valid Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate 415-670-3 78850-37-0 2021 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate 415-670-3 78850-37-0 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride 415-660-9 70918-74-0 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride 415-660-9 70918-74-0 2021 View substance registered dossier
ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active 1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride 415-660-9 70918-74-0 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Reaction mass of Pentaerythritol bis (2-ethylhexanoate) bis (3,5,5-trimethylhexanoate) and Pentaerythritol tris (2-ethylhexanoate) 3,5,5-trimethylhexanoate and Pentaerythritol 2-ethylhexanoate tris (3,5,5-trimethylhexanoate) and Pentaeryhthritol tetrakis(2-ethylhexanoate) and Pentaerythritol tetrakis (3,5,5-trimethylhexanoate) 415-650-4 153965-54-9 - View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR81 Hambakenwetering 7 5231 DD 's-Hertogenbosch Netherlands Netherlands Active Reaction mass of Pentaerythritol bis (2-ethylhexanoate) bis (3,5,5-trimethylhexanoate) and Pentaerythritol tris (2-ethylhexanoate) 3,5,5-trimethylhexanoate and Pentaerythritol 2-ethylhexanoate tris (3,5,5-trimethylhexanoate) and Pentaeryhthritol tetrakis(2-ethylhexanoate) and Pentaerythritol tetrakis (3,5,5-trimethylhexanoate) 415-650-4 153965-54-9 2018; 2020 View substance registered dossier
JX Nippon Oil & Energy Europe Limited 4th Floor, 4 Moorgate EC2R 6DA London United Kingdom United Kingdom No longer Valid Reaction mass of Pentaerythritol bis (2-ethylhexanoate) bis (3,5,5-trimethylhexanoate) and Pentaerythritol tris (2-ethylhexanoate) 3,5,5-trimethylhexanoate and Pentaerythritol 2-ethylhexanoate tris (3,5,5-trimethylhexanoate) and Pentaeryhthritol tetrakis(2-ethylhexanoate) and Pentaerythritol tetrakis (3,5,5-trimethylhexanoate) 415-650-4 153965-54-9 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active METHYLSECODION 415-640-1 - - View substance registered dossier
- - - - 5-ethoxy-1,3-dimethyl-1,3-dihydroindol-2-one 415-630-5 131057-63-1 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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