Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
1-(sec-butylphenyl(phenyl)-2-phenylethane, mixed isomers;1-(sec-butylphenyl-1-phenylethane, mixed isomers;reaction mass of: sec-butylphenyl(phenyl)methane, mixed isomers
431-100-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-(trimethylsilyloxy)-hexane
823-658-8 17888-62-9 Active Intermediate Individual Intermediate use only 08-08-2018 View substance registered dossier
1-[(1Ξ,2Ξ)-2-Chloro-1-hydroxy-3-(quinolin-6-yl)propyl]pyrrolidine-2,5-dione
811-462-5 1197377-31-3 Active Intermediate Individual Intermediate use only 16-10-2018 View substance registered dossier
1-[(2-butyloctyl)oxy]-3-(3,4-dihydroisoquinolinium-2-yl)propan-2-yl sulfate
470-080-3 - Active Full Individual ≥ 10 to < 100 tonnes 10-05-2011 View substance registered dossier
1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile
849-893-6 256376-65-5 Active Intermediate Individual Intermediate use only 17-07-2020 View substance registered dossier
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol
AMBER CORE
412-300-2 139504-68-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]pyrrolidine-2,5-dione
700-068-8 103953-71-5 Active Intermediate Individual Intermediate use only 28-10-2008 View substance registered dossier
1-[(2R)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone
700-612-4 1333469-23-0 Active Intermediate Individual Intermediate use only 15-06-2011 View substance registered dossier
1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine
601-832-2 122151-32-0 Active Intermediate Individual Intermediate use only 08-02-2018 View substance registered dossier
1-[(2S)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone
700-605-6 1333469-32-1 Active Intermediate Individual Intermediate use only 15-06-2011 View substance registered dossier
1-[(3,3-diphenylpropyl)(methyl)amino]-2-methyl-2-propanol
700-254-9 100442-33-9 Active Intermediate Individual Intermediate use only 29-09-2015 View substance registered dossier
1-[2-[(S)-(4-Chlorophenyl)phenylmethoxy]ethyl]piperidine hydrochloride
606-899-1 220282-83-7 Active Intermediate Individual Intermediate use only 12-12-2017 View substance registered dossier
1-[3,5-bis(benzyloxy)phenyl]-2-bromoethanone - 1,4-dioxane (2:1)
944-082-4 - Active Intermediate Individual Intermediate use only 21-05-2019 View substance registered dossier
1-[3-(Hydroxymethyl)pyridin-2-yl)-4-methyl-2-phenylpiperazine
700-296-8 61337-89-1 Active Intermediate Individual Intermediate use only 29-01-2009 View substance registered dossier
1-[3-(trifluoromethyl)phenyl]piperazinium chloride
240-153-2 16015-69-3 Active Intermediate Individual Intermediate use only 05-09-2019 View substance registered dossier
1-[3-[4-(4-cyanophenyl)-heteromonocycle-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-heteromonocycle-4-ium chloride
- - Active Intermediate Individual Intermediate use only 12-04-2018 View substance registered dossier
1-[3-alkyl-5-(6-hydroxynaphthalen-2-yl)-4-substitutedphenyl]pyrimidine-2,4(1H,3H)-dione
- - Active Intermediate Individual Intermediate use only 20-11-2013 View substance registered dossier
1-[4-(2-dimethylaminoethoxy)phenyl]-2-phenylbutan-1-one
CP-319,755
426-600-6 68047-07-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-[4-(2-dimethylaminoethylsulfonyl)-phenyl-3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazole
HOSTALUX VP 3481
401-410-6 10357-99-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-[4-(4-benzoylphenylsulfanyl)phenyl]-2-methyl-2-(4-methylphenylsulfonyl)propan-1-one
429-040-0 272460-97-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]ethanone
813-142-0 1417782-28-5 Active Intermediate Individual Intermediate use only 23-11-2016 View substance registered dossier
1-[4-(phenylthio)phenyl]octane-1,2-dione 2-(O-benzoyloxime)
454-610-0 253585-83-0 Cease Manufacture NONS Individual Cease manufacture 19-08-2011 View substance registered dossier
1-[4-chloro-3-((2,2,3,3,3-pentafluoropropoxy)methyl)phenyl]-5-phenyl-1H-1,2,4-triazole-3-carboxamide
FLUPOXAM
411-750-7 119126-15-7 No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
1-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]ethanone
807-008-0 1173693-36-1 Active Full Individual ≥ 100 to < 1 000 tonnes 10-07-2017 View substance registered dossier
1-[di(4-octylphenyl)aminomethyl]-4-methyl-1H-benzotriazole;N-[(4-methyl-1H-benzotriazol-1-yl)methyl]-4-octyl-N-(4-octylphenyl)aniline;reaction mass of: 1-[di(4-octylphenyl)aminomethyl]-5-methyl-1H-benzotriazole;reaction mass of: N-[(5-methyl-1H-benzotriazol-1-yl)methyl]-4-octyl-N-(4-octylphenyl)aniline
420-720-2 - Active NONS Individual Tonnage data confidential 30-11-2021 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-(sec-butylphenyl(phenyl)-2-phenylethane, mixed isomers;1-(sec-butylphenyl-1-phenylethane, mixed isomers;reaction mass of: sec-butylphenyl(phenyl)methane, mixed isomers 431-100-6 - - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active 1-(trimethylsilyloxy)-hexane 823-658-8 17888-62-9 2018 View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active 1-[(1Ξ,2Ξ)-2-Chloro-1-hydroxy-3-(quinolin-6-yl)propyl]pyrrolidine-2,5-dione 811-462-5 1197377-31-3 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-[(2-butyloctyl)oxy]-3-(3,4-dihydroisoquinolinium-2-yl)propan-2-yl sulfate 470-080-3 - 2011 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile 849-893-6 256376-65-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]pyrrolidine-2,5-dione 700-068-8 103953-71-5 - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active 1-[(2R)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone 700-612-4 1333469-23-0 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active 1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine 601-832-2 122151-32-0 - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active 1-[(2S)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone 700-605-6 1333469-32-1 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1-[(3,3-diphenylpropyl)(methyl)amino]-2-methyl-2-propanol 700-254-9 100442-33-9 2010; 2015 View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active 1-[2-[(S)-(4-Chlorophenyl)phenylmethoxy]ethyl]piperidine hydrochloride 606-899-1 220282-83-7 - View substance registered dossier
AstraZeneca B 313:5 AZ GlobalSHE- Chem.Reg. 15185 Södertälje Sweden Sweden Active 1-[3,5-bis(benzyloxy)phenyl]-2-bromoethanone - 1,4-dioxane (2:1) 944-082-4 - 2019 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 1-[3-(Hydroxymethyl)pyridin-2-yl)-4-methyl-2-phenylpiperazine 700-296-8 61337-89-1 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active 1-[3-(trifluoromethyl)phenyl]piperazinium chloride 240-153-2 16015-69-3 - View substance registered dossier
[Confidential] - - - 1-[3-[4-(4-cyanophenyl)-heteromonocycle-2-yl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-heteromonocycle-4-ium chloride - - - View substance registered dossier
[Confidential] - - - 1-[3-alkyl-5-(6-hydroxynaphthalen-2-yl)-4-substitutedphenyl]pyrimidine-2,4(1H,3H)-dione - - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 1-[4-(2-dimethylaminoethoxy)phenyl]-2-phenylbutan-1-one 426-600-6 68047-07-4 - View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Active 1-[4-(2-dimethylaminoethylsulfonyl)-phenyl-3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazole 401-410-6 10357-99-0 - View substance registered dossier
IGM Resins Italia S.r.l Via Vincenzo Monti, 8 20123 Milano Italy Italy Active 1-[4-(4-benzoylphenylsulfanyl)phenyl]-2-methyl-2-(4-methylphenylsulfonyl)propan-1-one 429-040-0 272460-97-6 - View substance registered dossier
[Confidential] - - - 1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]ethanone 813-142-0 1417782-28-5 - View substance registered dossier
BASF Italia S.p.A. OR15 Via Marconato 8 20811 Cesano Maderno Italy Italy Cease Manufacture 1-[4-(phenylthio)phenyl]octane-1,2-dione 2-(O-benzoyloxime) 454-610-0 253585-83-0 2013 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 1-[4-chloro-3-((2,2,3,3,3-pentafluoropropoxy)methyl)phenyl]-5-phenyl-1H-1,2,4-triazole-3-carboxamide 411-750-7 119126-15-7 2021 View substance registered dossier
DuPont Solutions (France) SAS Equinoxe 2 1bis avenue du 8 Mai 1945 78280 Guyancour France France Active 1-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]ethanone 807-008-0 1173693-36-1 - View substance registered dossier
The Acta Group EU BVBA (BE1) Place du Luxembourg 2 1050 Brussels Belgium Belgium Active 1-[di(4-octylphenyl)aminomethyl]-4-methyl-1H-benzotriazole;N-[(4-methyl-1H-benzotriazol-1-yl)methyl]-4-octyl-N-(4-octylphenyl)aniline;reaction mass of: 1-[di(4-octylphenyl)aminomethyl]-5-methyl-1H-benzotriazole;reaction mass of: N-[(5-methyl-1H-benzotriazol-1-yl)methyl]-4-octyl-N-(4-octylphenyl)aniline 420-720-2 - 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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