Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
Ethanone, 1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indol-1-yl]-
639-693-5 180637-88-1 Active Intermediate Joint Intermediate use only 05-08-2019 View substance registered dossier
Cistus ladaniferus, ext.
639-656-3 8016-26-0 Active Full Individual ≥ 10 to < 100 tonnes 13-09-2018 View substance registered dossier
Oils, neroli
639-655-8 8016-38-4 Active Full Joint ≥ 0 to < 10 tonnes 08-10-2018 View substance registered dossier
Octanal, 2-(phenylmethylene)-, (2E)-
639-566-4 165184-98-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 01-09-2021 View substance registered dossier
D-Tryptophan, methyl ester, hydrochloride (1:1)
639-469-7 14907-27-8 Cease Manufacture Intermediate Individual Cease manufacture 28-03-2014 View substance registered dossier
3-oxocyclobutane-1-carboxylic acid
639-432-5 23761-23-1 Active Intermediate Joint Intermediate use only 10-05-2021 View substance registered dossier
2,2'-Bi-1,3,2-dioxaborinane, 5,5,5',5'-tetramethyl-
639-407-9 201733-56-4 Active Intermediate Joint Intermediate use only 12-05-2020 View substance registered dossier
2-fluoro-1-methyl-3-nitrobenzene
639-386-6 437-86-5 Active Intermediate Joint Intermediate use only 06-11-2020 View substance registered dossier
2,5-Dichloro-4,6-dimethyl-3-pyridincarbonitrile
639-346-8 91591-63-8 Active Intermediate Joint Intermediate use only 08-01-2019 View substance registered dossier
1H-Pyrazole-5-carboxamide, 4-[[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzoyl]amino]-1-methyl-3-propyl-
639-263-7 200575-15-1 Active Intermediate Individual Intermediate use only 12-04-2017 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active Ethanone, 1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indol-1-yl]- 639-693-5 180637-88-1 2017; 2019 View substance registered dossier
SEBASTIÁN PÉREZ E HIJOS, S.L. Avenida de Portugal, 33 21570 Santa Bárbara de Casa huelva Spain Spain Active Cistus ladaniferus, ext. 639-656-3 8016-26-0 2018 View substance registered dossier
Biolandes Route de Belis 40420 Le Sen Landes France France Active Oils, neroli 639-655-8 8016-38-4 - View substance registered dossier
LISAM TELEGIS Parc d'activités de Noyon-Passel 17 rue de la Couture 60400 Passel France France Active Oils, neroli 639-655-8 8016-38-4 2018 View substance registered dossier
Ramboll Deutschland GmbH Werinherstraße 79 Gebäude 32a 81541 München Germany Germany Active Oils, neroli 639-655-8 8016-38-4 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2012 View substance registered dossier
MANE OR Wayne 620 route de Grasse 06620 LE BAR SUR LOUP France France Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 - View substance registered dossier
Intertek Deutschland GmbH IEFC* Stangenstr.1 70771 Leinfelden-Echterdingen Germany Germany Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2014; 2015 View substance registered dossier
Kao Chemicals Europe, S.L. (4) Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2020 View substance registered dossier
Kao Corporation, S.A. Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2012; 2014; 2015 View substance registered dossier
Penman Consulting bvba 09 Avenue des Arts 10 B-1210 Brussels Belgium Belgium Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2013; 2014; 2017 View substance registered dossier
Penman Consulting bvba 10 Avenue des Arts 10 1210 Brussels Belgium Belgium Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2017; 2021 View substance registered dossier
Knoell NL_OR_060 Agro Business Park 75 6708 PV Wageningen Netherlands Netherlands Active Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2013; 2014; 2021 View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Cease Manufacture Octanal, 2-(phenylmethylene)-, (2E)- 639-566-4 165184-98-5 2016 View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Cease Manufacture D-Tryptophan, methyl ester, hydrochloride (1:1) 639-469-7 14907-27-8 2018 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active 3-oxocyclobutane-1-carboxylic acid 639-432-5 23761-23-1 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 3-oxocyclobutane-1-carboxylic acid 639-432-5 23761-23-1 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 2,2'-Bi-1,3,2-dioxaborinane, 5,5,5',5'-tetramethyl- 639-407-9 201733-56-4 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 2,2'-Bi-1,3,2-dioxaborinane, 5,5,5',5'-tetramethyl- 639-407-9 201733-56-4 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 2,2'-Bi-1,3,2-dioxaborinane, 5,5,5',5'-tetramethyl- 639-407-9 201733-56-4 2015 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-fluoro-1-methyl-3-nitrobenzene 639-386-6 437-86-5 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 2-fluoro-1-methyl-3-nitrobenzene 639-386-6 437-86-5 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 2,5-Dichloro-4,6-dimethyl-3-pyridincarbonitrile 639-346-8 91591-63-8 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 2,5-Dichloro-4,6-dimethyl-3-pyridincarbonitrile 639-346-8 91591-63-8 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 1H-Pyrazole-5-carboxamide, 4-[[2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzoyl]amino]-1-methyl-3-propyl- 639-263-7 200575-15-1 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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