Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate
404-740-9 115895-09-5 Active Full Individual ≥ 10 to < 100 tonnes 24-12-2020 View substance registered dossier
Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate
404-740-9 115895-09-5 Active Full Individual ≥ 1 to < 10 tonnes 05-02-2010 View substance registered dossier
Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate
404-740-9 115895-09-5 Cease Manufacture NONS Individual Cease manufacture 17-05-2021 View substance registered dossier
Ethyl 3,5-dichloro-4-hydroxybenzoate
241-331-2 17302-82-8 Active Intermediate Individual Intermediate use only 17-04-2018 View substance registered dossier
Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate
BIBR 1048 MANAMIDE
454-450-1 429659-01-8 Active Intermediate Individual Intermediate use only 17-08-2011 View substance registered dossier
Ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate
CA 875 B
414-450-4 88805-65-6 Active Intermediate Individual Intermediate use only 14-11-2012 View substance registered dossier
Ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate
CA 875 B
414-450-4 88805-65-6 No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
Ethyl 3-hydroxypropanoate
695-619-1 623-72-3 Active Full Individual ≥ 1 to < 10 tonnes 20-06-2022 View substance registered dossier
Ethyl 3-mercaptobutanoate
ETHYL 3-MERCAPTOBUTYRATE
435-460-5 156472-94-5 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
ethyl 4-((4-diethylamino-2-methylphenyl)imino)-4,5-dihydro-1-isopropyl-5-oxo-1H-pyrazole-3-carboxylate
427-110-5 948991-29-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
246-403-7 24683-26-9 Active Intermediate Individual Intermediate use only 09-03-2012 View substance registered dossier
ethyl 5,5-diphenyl-2-isoxazoline-3-carboxylate
443-870-0 163520-33-0 Active Full Individual ≥ 100 to < 1 000 tonnes 13-11-2015 View substance registered dossier
Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate
201-899-4 89-33-8 Active Intermediate Individual Intermediate use only 31-01-2014 View substance registered dossier
Ethyl 5-oxo-L-prolinate
230-480-9 7149-65-7 Active Intermediate Individual Intermediate use only 17-02-2017 View substance registered dossier
ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
948-272-8 503615-07-4 Active Intermediate Individual Intermediate use only 09-08-2018 View substance registered dossier
Ethyl 6-O-decanoyl-D-glucopyranoside
BIOSURF 10; PRIAZUL
418-590-7 124285-42-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl 6-O-dodecanoyl-D-glucopyranoside
BIOSURF 12
418-610-4 124285-43-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl 6-O-octadecenoyl-D-glucopyranoside
BIOSURF 18:1
418-620-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl acetate
205-500-4 141-78-6 No longer Valid Full Individual No longer valid 11-01-2016 View substance registered dossier
Ethyl chloroformate
208-778-5 541-41-3 Active Intermediate Individual Intermediate use only 15-10-2012 View substance registered dossier
ethyl cis-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate
428-030-3 67914-69-6 Active NONS Individual Tonnage data confidential 27-05-2013 View substance registered dossier
Ethyl cyanoacetate
203-309-0 105-56-6 Active Intermediate Individual Intermediate use only 19-04-2013 View substance registered dossier
Ethyl cyanoacetate
203-309-0 105-56-6 Active Intermediate Individual Intermediate use only 24-05-2013 View substance registered dossier
Ethyl difluoroacetate
207-223-4 454-31-9 Active Intermediate Individual Intermediate use only 02-08-2011 View substance registered dossier
Ethyl diphenylglycolate
257-713-7 52182-15-7 Active Intermediate Individual Intermediate use only 09-05-2018 View substance registered dossier
Ethyl diphenylphosphinite
211-951-8 719-80-2 Active Intermediate Individual Intermediate use only 18-01-2013 View substance registered dossier
Ethyl isocyanoacetate
221-077-9 2999-46-4 Active Intermediate Individual Intermediate use only 11-04-2016 View substance registered dossier
Ethyl isothiocyanate
208-831-2 542-85-8 Active Full Individual ≥ 1 to < 10 tonnes 16-10-2018 View substance registered dossier
Ethyl propoxy aluminium chloride
EAPOXC
421-790-7 13014-29-4 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Ethyl trans-2,2,6-trimethylcyclohexanecarboxylate
ET 344 SP
412-540-8 22471-55-2 Active NONS Individual Tonnage data confidential 08-01-2015 View substance registered dossier
Ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
257-522-9 51931-66-9 Active Intermediate Individual Intermediate use only 15-12-2016 View substance registered dossier
Ethylbenzene
202-849-4 100-41-4 No longer Valid Full Individual No longer valid 24-10-2011 View substance registered dossier
Ethylene oxide
200-849-9 75-21-8 Cease Manufacture Intermediate Individual Cease manufacture 27-07-2010 View substance registered dossier
Ethylene oxide
200-849-9 75-21-8 Active Intermediate Individual Intermediate use only 08-11-2012 View substance registered dossier
Ethylene oxide
200-849-9 75-21-8 Active Intermediate Individual Intermediate use only 31-10-2012 View substance registered dossier
Ethylene oxide
200-849-9 75-21-8 Active Intermediate Individual Intermediate use only 12-01-2011 View substance registered dossier
Ethylene polymerisation (triethylaluminium catalysed), distillation residue, C20-40 fraction
931-746-3 - No longer Valid Full Individual No longer valid 23-01-2013 View substance registered dossier
Ethylenebisinden-1-ylzirconiumdichloride
EURECEN 5036
456-950-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethylenediamine p-toluenesulphonate
230-728-6 7294-10-2 Active Intermediate Individual Intermediate use only 12-02-2018 View substance registered dossier
ethynyl cyclopropane
425-430-1 6746-94-7 Active Intermediate Individual Intermediate use only 05-09-2011 View substance registered dossier
Etilefrine
211-910-4 709-55-7 Cease Manufacture Intermediate Individual Cease manufacture 24-07-2014 View substance registered dossier
Eucalptus dives, phellandrene
947-708-4 - Active Intermediate Individual Intermediate use only 04-05-2018 View substance registered dossier
Eucalyptus maculata citriodora, ext.
Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Eucalyptus maculata citriodora, Myrtaceae.
286-249-8 85203-56-1 No longer Valid Intermediate Individual No longer valid 06-04-2018 View substance registered dossier
EURECEN 5030
416-970-7 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
europium aluminium silicate
453-010-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Europium trinitrate
233-380-3 10138-01-9 Active Intermediate Individual Intermediate use only 12-10-2017 View substance registered dossier
Exo-1-methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]heptan-2-ol
CINEOLE ALCOHOL
402-470-6 87172-89-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
exo-2-methyl-exo-3-methyl-endo-2-[(endo-3-methylbicyclo[2.2.1]hept-exo-2-yl)methyl]bicyclo[2.2.1]heptane;reaction mass of: endo-2-methyl-exo-3-methyl-exo-2-[(exo-3-methylbicyclo[2.2.1]hept-exo-2-yl)methyl]bicyclo[2.2.1]heptane
434-420-4 - Active NONS Individual Tonnage data confidential 07-11-2012 View substance registered dossier
Exolit OP 940
434-510-3 176316-86-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Extract oils (coal), tar base
The extract from coal tar oil alkaline extract residue produced by an acidic wash such as aqueous sulfuric acid after distillation to remove naphthalene. Composed primarily of the acid salts of various aromatic nitrogen bases including pyridine, quinoline, and their alkyl derivatives.
266-020-9 65996-86-3 Active Intermediate Individual Intermediate use only 14-04-2016 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate 404-740-9 115895-09-5 2012; 2014; 2015; 2020 View substance registered dossier
La Mesta Bourgogne Campus industriel Le Grand Chalon en Bourgogne Route de Demigny - BP21 71102 Chalon-sur-Saone France France Active Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate 404-740-9 115895-09-5 2010 View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Cease Manufacture Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate 404-740-9 115895-09-5 2021 View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active Ethyl 3,5-dichloro-4-hydroxybenzoate 241-331-2 17302-82-8 - View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate 454-450-1 429659-01-8 - View substance registered dossier
ESIM Chemicals GmbH St.-Peter-Strasse 25 4020 Linz Austria Austria Active Ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate 414-450-4 88805-65-6 2012 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid Ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate 414-450-4 88805-65-6 2021 View substance registered dossier
KTR Europe GmbH Mergenthalerallee 77 65760 Eschborn HE Germany Germany Active Ethyl 3-hydroxypropanoate 695-619-1 623-72-3 - View substance registered dossier
- - - - Ethyl 3-mercaptobutanoate 435-460-5 156472-94-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active ethyl 4-((4-diethylamino-2-methylphenyl)imino)-4,5-dihydro-1-isopropyl-5-oxo-1H-pyrazole-3-carboxylate 427-110-5 948991-29-5 - View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 246-403-7 24683-26-9 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active ethyl 5,5-diphenyl-2-isoxazoline-3-carboxylate 443-870-0 163520-33-0 2011; 2015 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active Ethyl 5-oxo-1-phenyl-2-pyrazoline-3-carboxylate 201-899-4 89-33-8 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active Ethyl 5-oxo-L-prolinate 230-480-9 7149-65-7 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate 948-272-8 503615-07-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Ethyl 6-O-decanoyl-D-glucopyranoside 418-590-7 124285-42-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Ethyl 6-O-dodecanoyl-D-glucopyranoside 418-610-4 124285-43-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active Ethyl 6-O-octadecenoyl-D-glucopyranoside 418-620-9 - - View substance registered dossier
Bestseller A/S Moltrup Landevej 201 6100 Haderslev Denmark Denmark No longer Valid Ethyl acetate 205-500-4 141-78-6 2017 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Ethyl chloroformate 208-778-5 541-41-3 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active ethyl cis-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine-1-carboxylate 428-030-3 67914-69-6 2010; 2013 View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active Ethyl cyanoacetate 203-309-0 105-56-6 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active Ethyl cyanoacetate 203-309-0 105-56-6 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Ethyl difluoroacetate 207-223-4 454-31-9 - View substance registered dossier
Katwijk Chemie BV Snijderstraat 6 Steenbakkerstraat 26 2222 BA Katwijk ZH Netherlands Netherlands Active Ethyl diphenylglycolate 257-713-7 52182-15-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Ethyl diphenylphosphinite 211-951-8 719-80-2 - View substance registered dossier
DB International BV Lange Muiderweg 582 1398 PA Muiden Netherlands Netherlands Active Ethyl isocyanoacetate 221-077-9 2999-46-4 2016 View substance registered dossier
Pharmasynthese 57, Rue Gravetel 76320 Saint Pierre lès Elbeuf HNO France France Active Ethyl isothiocyanate 208-831-2 542-85-8 2018 View substance registered dossier
LANXESS Organometallics GmbH Justus-von-Liebig Str. 1620 59192 Bergkamen 05 Germany Germany Cease Manufacture Ethyl propoxy aluminium chloride 421-790-7 13014-29-4 2022 View substance registered dossier
TAKASAGO TEPL-Importer 12 rue Torricelli 75017 Paris France France Active Ethyl trans-2,2,6-trimethylcyclohexanecarboxylate 412-540-8 22471-55-2 2015 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active Ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate 257-522-9 51931-66-9 - View substance registered dossier
Ecotoxward Ltd 381 -383 City Road EC1V 1NW London United Kingdom United Kingdom No longer Valid Ethylbenzene 202-849-4 100-41-4 2021 View substance registered dossier
Only representative (No publishable name) - - Cease Manufacture Ethylene oxide 200-849-9 75-21-8 2019 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 HW77 Dublin Ireland Ireland Active Ethylene oxide 200-849-9 75-21-8 2012 View substance registered dossier
Chemical Inspection & Regulation Service Limited Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland Ireland Active Ethylene oxide 200-849-9 75-21-8 2012 View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED 306 The Capel Building, Mary's Abbey, Dublin 7, Ireland Dublin 7 Dublin Ireland Ireland Active Ethylene oxide 200-849-9 75-21-8 2011 View substance registered dossier
Ineos Feluy SPRL Parc Industriel de Feluy Nord Zone C B-7181 Feluy Feluy Belgium Belgium No longer Valid Ethylene polymerisation (triethylaluminium catalysed), distillation residue, C20-40 fraction 931-746-3 - 2014 View substance registered dossier
- - - - Ethylenebisinden-1-ylzirconiumdichloride 456-950-5 - - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active Ethylenediamine p-toluenesulphonate 230-728-6 7294-10-2 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active ethynyl cyclopropane 425-430-1 6746-94-7 2009; 2011 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture Etilefrine 211-910-4 709-55-7 2019 View substance registered dossier
C.S.B. GmbH Duesseldorfer Str.113 47809 Krefeld Germany Germany Active Eucalptus dives, phellandrene 947-708-4 - - View substance registered dossier
Citrefine International Limited Moorfield Road Yeadon LS19 7BN Leeds West Yorkshire United Kingdom United Kingdom No longer Valid Eucalyptus maculata citriodora, ext. 286-249-8 85203-56-1 2021 View substance registered dossier
- - - - EURECEN 5030 416-970-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active europium aluminium silicate 453-010-6 - - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active Europium trinitrate 233-380-3 10138-01-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Exo-1-methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]heptan-2-ol 402-470-6 87172-89-2 - View substance registered dossier
Labcorp Development SA 046 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active exo-2-methyl-exo-3-methyl-endo-2-[(endo-3-methylbicyclo[2.2.1]hept-exo-2-yl)methyl]bicyclo[2.2.1]heptane;reaction mass of: endo-2-methyl-exo-3-methyl-exo-2-[(exo-3-methylbicyclo[2.2.1]hept-exo-2-yl)methyl]bicyclo[2.2.1]heptane 434-420-4 - 2012 View substance registered dossier
Clariant Plastics & Coatings (Deutschland) GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active Exolit OP 940 434-510-3 176316-86-2 - View substance registered dossier
Rain Carbon Germany GmbH Kekulestr. 30 44579 Castrop-Rauxel Germany Germany Active Extract oils (coal), tar base 266-020-9 65996-86-3 2016 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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