Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2R)-
603-315-7 129050-26-6 Active Full Joint ≥ 1 to < 10 tonnes 03-06-2019 View substance registered dossier
2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2R)-
603-315-7 129050-26-6 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2S)-
603-314-1 129050-23-3 Active Full Joint ≥ 0 to < 10 tonnes 03-06-2019 View substance registered dossier
2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2S)-
603-314-1 129050-23-3 Active Intermediate Joint Intermediate use only 13-02-2019 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-
619-405-4 99199-60-7 Cease Manufacture Intermediate Individual Cease manufacture 27-05-2013 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-
619-405-4 99199-60-7 Active Intermediate Individual Intermediate use only 22-07-2011 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-
619-405-4 99199-60-7 Active Intermediate Joint Intermediate use only 09-10-2019 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2R)-
810-841-2 129101-37-7 Active Intermediate Individual Intermediate use only 08-03-2016 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2S)-
810-842-8 129101-36-6 Active Intermediate Individual Intermediate use only 08-03-2016 View substance registered dossier
2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, methyl ester
484-280-3 874649-82-8 Active Intermediate Joint Intermediate use only 12-12-2019 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.R,.alpha.'R,2R,2'S)-
927-046-2 1180001-17-5 Active Intermediate Individual Intermediate use only 17-10-2014 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.R,.alpha.'R,2R,2'S)-
927-046-2 1180001-17-5 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.S,.alpha.'S,2R,2'S)-
807-022-7 1224567-85-4 Active Intermediate Individual Intermediate use only 17-10-2014 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.S,.alpha.'S,2R,2'S)-
807-022-7 1224567-85-4 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.R,2R)-
807-025-3 1315508-94-1 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.R,2S)-
807-026-9 1315508-93-0 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.S,2R)-
807-023-2 1315508-95-2 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.S,2S)-
807-024-8 1315508-96-3 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.R,2S)-
600-381-9 1030385-16-0 Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.R,2S)-
600-381-9 1030385-16-0 Active Intermediate Individual Intermediate use only 20-11-2014 View substance registered dossier
2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.S,2R)-
603-316-2 129050-27-7 Active Full Joint ≥ 1 to < 10 tonnes 16-01-2018 View substance registered dossier
2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.S,2R)-
603-316-2 129050-27-7 Active Intermediate Individual Intermediate use only 20-11-2014 View substance registered dossier
2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-α-[[(phenylmethyl)amino]methyl]-, (αS,2S)-
603-317-8 129050-29-9 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2H-1-Benzopyran-2-methanol, a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-, (aR,a'R,2R,2'S)-rel-
601-527-4 118457-14-0 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
2H-1-Benzopyran-2-methanol, alpha,alpha'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, (alphaR,alpha'R,2R,2'S)-rel-
618-043-4 876666-07-8 Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
2H-1-Benzopyran-2-one, 3,4-dihydro-6-methyl-4-phenyl-
609-846-0 40546-94-9 Active Intermediate Joint Intermediate use only 20-11-2021 View substance registered dossier
2H-1-Benzopyran-2-one, 6-bromo-3,4-dihydro-4-phenyl-
923-250-0 156755-23-6 Cease Manufacture Intermediate Individual Cease manufacture 07-07-2011 View substance registered dossier
2H-1-Benzopyran-5-carboxylic acid, 2-cyclopropyl-7,8-dimethoxy-
617-579-6 845276-37-1 Active Intermediate Joint Intermediate use only 07-05-2018 View substance registered dossier
2H-1-Benzopyran-5-methanol, 2-cyclopropyl-7,8-dimethoxy-
617-580-1 845276-38-2 Active Intermediate Joint Intermediate use only 07-05-2018 View substance registered dossier
2H-1-Benzopyran-5-propanenitrile, 2-cyclopropyl-7,8-dimethoxy-α-[(phenylamino)methylene]-
606-270-1 192315-08-5 Active Intermediate Joint Intermediate use only 05-05-2018 View substance registered dossier
2H-1-Benzopyran-6-methanol, 3,4-dihydro-2-hydroxy-4-phenyl-
700-143-5 959624-24-9 Cease Manufacture Intermediate Individual Cease manufacture 30-06-2009 View substance registered dossier
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-(dihydrogen phosphate), sodium salt (1:?)
478-070-0 299158-63-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2H-3,1-Benzoxazine-2,4(1H)-dione, 1-[3-(trifluoromethyl)phenyl]-
605-269-3 1618-64-0 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
2H-3,1-Benzoxazine-6-sulfonamide, 7-chloro-1,4-dihydro-2,4-dioxo-
811-480-3 23380-53-2 Active Intermediate Individual Intermediate use only 07-01-2016 View substance registered dossier
2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy-
456-160-0 73942-87-7 Active Full Individual ≥ 1 to < 10 tonnes 08-05-2014 View substance registered dossier
2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy-
456-160-0 73942-87-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2H-Azepin-2-one, 1,1'-(1,3-phenylenedicarbonyl)bis[hexahydro-
616-020-3 7381-13-7 Active Full Joint ≥ 1 to < 10 tonnes 18-12-2017 View substance registered dossier
2H-Azepin-2-one, hexahydro-, polymer with 1,6-diisocyanatohexane
607-997-7 26776-30-7 Active Full Joint ≥ 100 to < 1 000 tonnes 10-12-2020 View substance registered dossier
2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, hydrochloride (1:1)
813-873-5 62781-53-7 Active Intermediate Joint Intermediate use only 18-05-2017 View substance registered dossier
2H-Benzimidazole-2-thione, 1,3-dihydro-ar-methyl-, sodium salt (1:1)
939-407-1 75045-07-7 Active Intermediate Joint Intermediate use only 20-01-2020 View substance registered dossier
2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro-
619-308-7 97963-62-7 Active Intermediate Joint Intermediate use only 28-08-2018 View substance registered dossier
2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro-
417-780-7 97963-62-7 Active Intermediate Individual Intermediate use only 21-05-2010 View substance registered dossier
2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro-
417-780-7 97963-62-7 Active Intermediate Individual Intermediate use only 17-11-2014 View substance registered dossier
2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro-
417-780-7 97963-62-7 Active Intermediate Individual Intermediate use only 16-03-2010 View substance registered dossier
2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro-
417-780-7 97963-62-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro-
417-780-7 97963-62-7 Active Intermediate Joint Intermediate use only 17-05-2022 View substance registered dossier
2H-Indazol-6-amine, 2,3-dimethyl-
610-188-1 444731-72-0 Active Intermediate Joint Intermediate use only 25-11-2021 View substance registered dossier
2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl-
810-051-8 444731-74-2 Active Intermediate Joint Intermediate use only 25-11-2021 View substance registered dossier
2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl-
810-050-2 444731-75-3 Active Intermediate Joint Intermediate use only 26-11-2021 View substance registered dossier
2H-Indol-2-one, 1,3-dihydro-1-phenyl-
441-020-3 3335-98-6 Active Intermediate Joint Intermediate use only 10-02-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2R)- 603-315-7 129050-26-6 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2R)- 603-315-7 129050-26-6 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2S)- 603-314-1 129050-23-3 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2S)- 603-314-1 129050-23-3 - View substance registered dossier
Chemsafe S.r.l. Via Ribes 5 10010 Colleretto Giacosa (TO) Italy Italy Cease Manufacture 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro- 619-405-4 99199-60-7 2015 View substance registered dossier
SYNTESIA CHEMIE GmbH Martinistr. 13 20251 Hamburg Germany Germany Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro- 619-405-4 99199-60-7 - View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro- 619-405-4 99199-60-7 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2R)- 810-841-2 129101-37-7 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, (2S)- 810-842-8 129101-36-6 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, methyl ester 484-280-3 874649-82-8 2010; 2013; 2018 View substance registered dossier
ZaCh System ZI La Croix Cadeaux 49242 Avrillè France France Active 2H-1-Benzopyran-2-carboxylic acid, 6-fluoro-3,4-dihydro-, methyl ester 484-280-3 874649-82-8 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.R,.alpha.'R,2R,2'S)- 927-046-2 1180001-17-5 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.R,.alpha.'R,2R,2'S)- 927-046-2 1180001-17-5 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.S,.alpha.'S,2R,2'S)- 807-022-7 1224567-85-4 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-2-methanol, .alpha.,.alpha.'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, hydrochloride (1:1), (.alpha.S,.alpha.'S,2R,2'S)- 807-022-7 1224567-85-4 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.R,2R)- 807-025-3 1315508-94-1 2017 View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.R,2R)- 807-025-3 1315508-94-1 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.R,2S)- 807-026-9 1315508-93-0 2016 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.R,2S)- 807-026-9 1315508-93-0 2017 View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.S,2R)- 807-023-2 1315508-95-2 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.S,2R)- 807-023-2 1315508-95-2 2017 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.S,2S)- 807-024-8 1315508-96-3 2017 View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active 2H-1-Benzopyran-2-methanol, .alpha.-(chloromethyl)-6-fluoro-3,4-dihydro-, (.alpha.S,2S)- 807-024-8 1315508-96-3 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.R,2S)- 600-381-9 1030385-16-0 2018 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.R,2S)- 600-381-9 1030385-16-0 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.R,2S)- 600-381-9 1030385-16-0 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.S,2R)- 603-316-2 129050-27-7 2018 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-.alpha.-[[(phenylmethyl)amino]methyl]-, (.alpha.S,2R)- 603-316-2 129050-27-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-2-methanol, 6-fluoro-3,4-dihydro-α-[[(phenylmethyl)amino]methyl]-, (αS,2S)- 603-317-8 129050-29-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-2-methanol, a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-, (aR,a'R,2R,2'S)-rel- 601-527-4 118457-14-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-2-methanol, alpha,alpha'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, (alphaR,alpha'R,2R,2'S)-rel- 618-043-4 876666-07-8 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 2H-1-Benzopyran-2-methanol, alpha,alpha'-[[(phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-, (alphaR,alpha'R,2R,2'S)-rel- 618-043-4 876666-07-8 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 2H-1-Benzopyran-2-one, 3,4-dihydro-6-methyl-4-phenyl- 609-846-0 40546-94-9 - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active 2H-1-Benzopyran-2-one, 3,4-dihydro-6-methyl-4-phenyl- 609-846-0 40546-94-9 2019; 2020; 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Cease Manufacture 2H-1-Benzopyran-2-one, 6-bromo-3,4-dihydro-4-phenyl- 923-250-0 156755-23-6 2015 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-5-carboxylic acid, 2-cyclopropyl-7,8-dimethoxy- 617-579-6 845276-37-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-5-methanol, 2-cyclopropyl-7,8-dimethoxy- 617-580-1 845276-38-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran-5-propanenitrile, 2-cyclopropyl-7,8-dimethoxy-α-[(phenylamino)methylene]- 606-270-1 192315-08-5 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Cease Manufacture 2H-1-Benzopyran-6-methanol, 3,4-dihydro-2-hydroxy-4-phenyl- 700-143-5 959624-24-9 2015 View substance registered dossier
- - - - 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-(dihydrogen phosphate), sodium salt (1:?) 478-070-0 299158-63-7 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-[3-(trifluoromethyl)phenyl]- 605-269-3 1618-64-0 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2H-3,1-Benzoxazine-6-sulfonamide, 7-chloro-1,4-dihydro-2,4-dioxo- 811-480-3 23380-53-2 - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active 2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy- 456-160-0 73942-87-7 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy- 456-160-0 73942-87-7 - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture 2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy- 456-160-0 73942-87-7 2019 View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active 2H-3-Benzazepin-2-one, 1,3-dihydro-7,8-dimethoxy- 456-160-0 73942-87-7 - View substance registered dossier
BrüggemannChemical, L. Brüggemann GmbH & Co. KG Salzstrasse 131 74076 Heilbronn Baden-Württemberg Germany Germany Active 2H-Azepin-2-one, 1,1'-(1,3-phenylenedicarbonyl)bis[hexahydro- 616-020-3 7381-13-7 2016 View substance registered dossier
[Confidential] - - - 2H-Azepin-2-one, 1,1'-(1,3-phenylenedicarbonyl)bis[hexahydro- 616-020-3 7381-13-7 - View substance registered dossier
CS Regulatory Ireland Ltd. in its legal capacity as OR for LANXESS Urethanes UK Ltd Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland Ireland Active 2H-Azepin-2-one, hexahydro-, polymer with 1,6-diisocyanatohexane 607-997-7 26776-30-7 - View substance registered dossier
Covestro Deutschland AG Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany Germany Active 2H-Azepin-2-one, hexahydro-, polymer with 1,6-diisocyanatohexane 607-997-7 26776-30-7 2019 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 2H-Azepin-2-one, hexahydro-, polymer with 1,6-diisocyanatohexane 607-997-7 26776-30-7 2019 View substance registered dossier
Valspar b.v. Zuiveringweg 89 8243 PE Lelystad Netherlands Netherlands Active 2H-Azepin-2-one, hexahydro-, polymer with 1,6-diisocyanatohexane 607-997-7 26776-30-7 2020 View substance registered dossier
Axalta Coating Systems Germany GmbH & Co. KG Christbusch 25 42285 Wuppertal Germany Germany Active 2H-Azepin-2-one, hexahydro-, polymer with 1,6-diisocyanatohexane 607-997-7 26776-30-7 2018 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-, hydrochloride (1:1) 813-873-5 62781-53-7 - View substance registered dossier
LANXESS N.V. Scheldelaan 420 Haven 507 2040 Antwerpen Belgium Belgium Active 2H-Benzimidazole-2-thione, 1,3-dihydro-ar-methyl-, sodium salt (1:1) 939-407-1 75045-07-7 2016; 2019; 2020 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 619-308-7 97963-62-7 2018 View substance registered dossier
LAVOLLEE SA 9 rue Louis Rouquier 92300 Levallois Perret France France Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 619-308-7 97963-62-7 - View substance registered dossier
MOEHS CANTABRA P.I.Requejada Z-23 39313 Polanco Cantabria Spain Spain Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 - View substance registered dossier
Takeda GmbH Byk-Gulden-Strasse 2 78467 Konstanz Baden-Württemberg Germany Germany Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 2022 View substance registered dossier
MOEHS CANTABRA P.I.Requejada Z-23 39313 Polanco Cantabria Spain Spain Active 2H-Benzimidazole-2-thione, 5-(difluoromethoxy)-1,3-dihydro- 417-780-7 97963-62-7 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-Indazol-6-amine, 2,3-dimethyl- 610-188-1 444731-72-0 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 2H-Indazol-6-amine, 2,3-dimethyl- 610-188-1 444731-72-0 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl- 810-051-8 444731-74-2 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl- 810-051-8 444731-74-2 2018; 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl- 810-050-2 444731-75-3 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 2H-Indazol-6-amine, N-(2-chloro-4-pyrimidinyl)-N,2,3-trimethyl- 810-050-2 444731-75-3 2018; 2021 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 2H-Indol-2-one, 1,3-dihydro-1-phenyl- 441-020-3 3335-98-6 2010; 2012; 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-Indol-2-one, 1,3-dihydro-1-phenyl- 441-020-3 3335-98-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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