Registered substances

Registered substances

Registered substances

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid
444-810-6 - Active Full Joint ≥ 10 to < 100 tonnes 11-05-2021 View substance registered dossier
(2S-cis)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
255-795-9 42399-40-6 Active Intermediate Joint Intermediate use only 09-04-2018 View substance registered dossier
(2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid
279-393-8 80082-65-1 Active Intermediate Joint Intermediate use only 23-02-2018 View substance registered dossier
(2Z)-2-phenylhex-2-enenitrile
482-160-5 130786-09-3 Active Full Joint ≥ 10 to < 100 tonnes 27-08-2020 View substance registered dossier
(2Z)-4,8-dimethylnona-2,7-dien-4-ol
807-754-7 89929-57-7 Active Full Joint ≥ 1 to < 10 tonnes 27-05-2019 View substance registered dossier
(2Z)-7-chloro-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid
618-065-4 877674-77-6 Active Intermediate Joint Intermediate use only 13-09-2017 View substance registered dossier
(2α,4aα,8α)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one
249-649-3 29461-14-1 Active Full Joint ≥ 0 to < 10 tonnes 07-11-2017 View substance registered dossier
(2α,4aα,8β)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one
249-648-8 29461-13-0 Cease Manufacture Full Joint Cease manufacture 24-12-2019 View substance registered dossier
(2α,6α,11R*)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide
248-106-8 26918-40-1 Active Intermediate Joint Intermediate use only 26-04-2018 View substance registered dossier
(3'-carboxymethyl-5-(2-(3-ethyl-3H-benzothiazol-2-ylidene)-1-methyl-ethylidene)-4,4'-dioxo-2'-thioxo-(2,5')bithiazolidinyliden-3-yl)-acetic acid
CIN 10094329; SENSIBILISATOR KF 693 PINA; SENSITIZER KF 693 PINA
422-240-9 166596-68-5 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3,4-diethoxyphenyl)acetonitrile
248-479-7 27472-21-5 Active Intermediate Joint Intermediate use only 06-01-2022 View substance registered dossier
(3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane)
951-684-0 - Active Intermediate Joint Intermediate use only 26-02-2021 View substance registered dossier
(3-(4-(2-(butyl-(4-methylphenylsulfonyl)amino)phenylthio)-5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazole-3-ylamino)-4-chlorophenyl)tetradecanamide;N-[3-({4-[(2-{butyl[(4-methylphenyl)sulfonyl]amino}phenyl)thio]-5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl}amino)-4-chlorophenyl]tetradecanamide
432-970-1 217324-98-6 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3-acetyloxy-2,2-dimethylpropyl) acetate
826-122-1 13431-57-7 Active Full Joint ≥ 100 to < 1 000 tonnes 04-11-2019 View substance registered dossier
(3-acetyloxy-5-carbonochloridoylphenyl) acetate
855-283-0 39192-49-9 Active Intermediate Joint Intermediate use only 05-06-2020 View substance registered dossier
(3-aminophenyl)urea
247-201-1 25711-72-2 Active Full Joint ≥ 1 to < 10 tonnes 10-05-2017 View substance registered dossier
(3-aminophenyl)uronium chloride
261-858-1 59690-88-9 Active Full Joint ≥ 1 to < 10 tonnes 29-04-2013 View substance registered dossier
(3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate
280-734-8 83763-48-8 Active Full Joint ≥ 10 to < 100 tonnes 05-07-2021 View substance registered dossier
(3-bromopropyl)benzene
211-294-7 637-59-2 Active Intermediate Joint Intermediate use only 14-05-2018 View substance registered dossier
(3-carboxy-1,1'-(1,2-dicyanovinylenebis(nitrilomethylidyne)-2,2'-dinaphtholato)nickel(II)
POLYSYNTHREN-VIOLETT G
403-550-3 205057-15-4 Active NONS Joint Tonnage data confidential 29-07-2011 View substance registered dossier
(3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide
629-007-2 17857-14-6 Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
(3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride
255-578-9 41892-01-7 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
(3-chloro-2-hydroxypropyl)trimethylammonium chloride
222-048-3 3327-22-8 Active Full Joint ≥ 10 to < 100 tonnes 30-05-2018 View substance registered dossier
(3-chloro-2-hydroxypropyl)trimethylammonium chloride
222-048-3 3327-22-8 Active Intermediate Joint Intermediate use only 29-07-2021 View substance registered dossier
(3-chloroprop-1-enyl)benzene
220-246-4 2687-12-9 Active Full Joint ≥ 10 to < 100 tonnes 08-05-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid 444-810-6 - 2014; 2021 View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active (2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid 444-810-6 - - View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active (2S-cis)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-795-9 42399-40-6 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Active (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid 279-393-8 80082-65-1 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid 279-393-8 80082-65-1 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2Z)-2-phenylhex-2-enenitrile 482-160-5 130786-09-3 2020 View substance registered dossier
FIRMENICH GRASSE SAS OR 2 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2Z)-2-phenylhex-2-enenitrile 482-160-5 130786-09-3 2020 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2Z)-4,8-dimethylnona-2,7-dien-4-ol 807-754-7 89929-57-7 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (2Z)-7-chloro-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid 618-065-4 877674-77-6 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2α,4aα,8α)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one 249-649-3 29461-14-1 2017 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Cease Manufacture (2α,4aα,8β)-hexahydro-1,1,5,5-tetramethyl-2H-2,4a-methanonaphthalen-8(5H)-one 249-648-8 29461-13-0 2020 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2α,6α,11R*)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide 248-106-8 26918-40-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3'-carboxymethyl-5-(2-(3-ethyl-3H-benzothiazol-2-ylidene)-1-methyl-ethylidene)-4,4'-dioxo-2'-thioxo-(2,5')bithiazolidinyliden-3-yl)-acetic acid 422-240-9 166596-68-5 - View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (3,4-diethoxyphenyl)acetonitrile 248-479-7 27472-21-5 2022 View substance registered dossier
[Confidential] - - - (3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane) 951-684-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (3-(4-(2-(butyl-(4-methylphenylsulfonyl)amino)phenylthio)-5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazole-3-ylamino)-4-chlorophenyl)tetradecanamide;N-[3-({4-[(2-{butyl[(4-methylphenyl)sulfonyl]amino}phenyl)thio]-5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl}amino)-4-chlorophenyl]tetradecanamide 432-970-1 217324-98-6 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture (3-(4-(2-(butyl-(4-methylphenylsulfonyl)amino)phenylthio)-5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazole-3-ylamino)-4-chlorophenyl)tetradecanamide;N-[3-({4-[(2-{butyl[(4-methylphenyl)sulfonyl]amino}phenyl)thio]-5-oxo-1-(2,4,6-trichlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl}amino)-4-chlorophenyl]tetradecanamide 432-970-1 217324-98-6 2012 View substance registered dossier
Monument Chemical Haven 1972 Ketenislaan 3 9130 Kallo Belgium Belgium Active (3-acetyloxy-2,2-dimethylpropyl) acetate 826-122-1 13431-57-7 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (3-acetyloxy-2,2-dimethylpropyl) acetate 826-122-1 13431-57-7 2019 View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active (3-acetyloxy-5-carbonochloridoylphenyl) acetate 855-283-0 39192-49-9 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active (3-aminophenyl)urea 247-201-1 25711-72-2 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active (3-aminophenyl)uronium chloride 261-858-1 59690-88-9 - View substance registered dossier
James Robinson Speciality Ingredients BV Office 12.15 Millenium Tower Radarweg 29 / 12B 1043NX Amsterdam Netherlands Netherlands Active (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate 280-734-8 83763-48-8 2019; 2021 View substance registered dossier
Amik Italia VIA MECENATE 84B 20138 MILANO Italy Italy Italy Active (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate 280-734-8 83763-48-8 2019 View substance registered dossier
Jos. H. Lowenstein & Sons B.V. Naritaweg 165 1043 BW Amsterdam Netherlands Netherlands Active (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate 280-734-8 83763-48-8 - View substance registered dossier
Dragon Chemical Europe GmbH Carlsplatz 24 40213 Düsseldorf Germany Germany Active (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate 280-734-8 83763-48-8 2019 View substance registered dossier
COSMOLIFE SAS 25 rue des ALOUETTES 95150 TAVERNY France France Active (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate 280-734-8 83763-48-8 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate 280-734-8 83763-48-8 - View substance registered dossier
Artec Europe BV Vivaldistraat 3 7132 AG Lichtenvoorde Netherlands Netherlands Active (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate 280-734-8 83763-48-8 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active (3-bromopropyl)benzene 211-294-7 637-59-2 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (3-bromopropyl)benzene 211-294-7 637-59-2 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active (3-carboxy-1,1'-(1,2-dicyanovinylenebis(nitrilomethylidyne)-2,2'-dinaphtholato)nickel(II) 403-550-3 205057-15-4 2011 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture (3-carboxy-1,1'-(1,2-dicyanovinylenebis(nitrilomethylidyne)-2,2'-dinaphtholato)nickel(II) 403-550-3 205057-15-4 2014 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide 629-007-2 17857-14-6 - View substance registered dossier
Lubrizol Advanced Materials Europe B.V.B.A Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium Belgium Active (3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride 255-578-9 41892-01-7 - View substance registered dossier
DOW BENELUX B.V. OR-3 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride 255-578-9 41892-01-7 - View substance registered dossier
Ricardo Nederland BV Catharijnesingel 33 3511 GC Utrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride 255-578-9 41892-01-7 2018 View substance registered dossier
Innospec Performance Chemicals France SAS (Only Rep) Zone Industrielle de Han Sur Meuse BP19 55300 Saint-Mihiel France France Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Rudolf GmbH Altvaterstr. 58 - 64 82538 Geretsried Germany Germany Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
TSafeE GmbH Landwehrpl 6 66111 Saarbrücken Germany Germany Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Ricardo Nederland BV Catharijnesingel 33 3511 GC Utrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2011; 2021 View substance registered dossier
Sachem Europe BV Van Voordenpark 15 5301 KP Zaltbommel Gelderland Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2010; 2014 View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Ingredion Germany GmbH Gruner Deich 110 20097 Hamburg Germany Germany Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Nalco Limited P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom United Kingdom No longer Valid (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2021 View substance registered dossier
Ashland Services BV (0311) Noordweg 9 3336 LH Zwijndrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Chemigate Oy Simpsiöntie 682 62100 Lapua Finland Finland Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
DOW BENELUX B.V. - OR1 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2012 View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
ROQUETTE Frères 1 rue de la haute loge 62136 LESTREM Cedex France France Cease Manufacture (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2021 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (3-chloroprop-1-enyl)benzene 220-246-4 2687-12-9 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (3-chloroprop-1-enyl)benzene 220-246-4 2687-12-9 2018; 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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