Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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2-pyrrolidin-1-ylethanol
220-976-3 2955-88-6 Active Intermediate Joint Intermediate use only 06-07-2017 View substance registered dossier
2-Pyrrolidinone, 5-ethenyl-
616-206-4 7529-16-0 Active Intermediate Individual Intermediate use only 16-11-2012 View substance registered dossier
2-pyrrolidone
210-483-1 616-45-5 Active Intermediate Joint Intermediate use only 04-10-2018 View substance registered dossier
2-Quinolinamine, 8-chloro-N-[4-(trihalomethoxy)aryl]-, halide
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
2-tBuPDI ligand
- - Active Intermediate Joint Intermediate use only 27-04-2022 View substance registered dossier
2-tert-butoxyethanol
456-140-1 - Active Intermediate Individual Intermediate use only 11-10-2019 View substance registered dossier
2-tert-butyl-p-cresol
219-314-6 2409-55-4 Active Intermediate Joint Intermediate use only 19-03-2013 View substance registered dossier
2-tert-butyl-p-cresol
219-314-6 2409-55-4 Active Intermediate Individual Intermediate use only 04-07-2012 View substance registered dossier
2-thenoic acid
208-423-4 527-72-0 Active Intermediate Joint Intermediate use only 02-04-2019 View substance registered dossier
2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
608-646-0 3159-07-7 Active Intermediate Joint Intermediate use only 22-05-2018 View substance registered dossier
2-thiazolidinylidenecyanamide
427-720-1 26364-65-8 Active Intermediate Individual Intermediate use only 21-12-2010 View substance registered dossier
2-thienylacetic acid
217-639-8 1918-77-0 Active Intermediate Joint Intermediate use only 22-06-2020 View substance registered dossier
2-thienylacetic acid
217-639-8 1918-77-0 Active Intermediate Joint Intermediate use only 14-03-2022 View substance registered dossier
2-thienylacetonitrile
244-104-6 20893-30-5 Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
2-thienylacetyl chloride
254-290-0 39098-97-0 Active Intermediate Joint Intermediate use only 24-03-2021 View substance registered dossier
2-thienylacetyl chloride
254-290-0 39098-97-0 Active Intermediate Joint Intermediate use only 07-01-2020 View substance registered dossier
2-thienylcarbonyl chloride
226-092-4 5271-67-0 Active Intermediate Joint Intermediate use only 18-08-2015 View substance registered dossier
2-thiobarbituric acid
207-985-8 504-17-6 Active Intermediate Joint Intermediate use only 05-10-2018 View substance registered dossier
2-Thiopheneacetic acid, .alpha.-methyl-
611-216-5 54955-39-4 Active Intermediate Joint Intermediate use only 18-10-2016 View substance registered dossier
2-Thiopheneacetic acid, 5-benzoyl-.alpha.-methyl-, sodium salt (1:1)
923-143-9 59173-03-4 Active Intermediate Joint Intermediate use only 28-03-2017 View substance registered dossier
2-Thiophenecarboxylic acid, 3-[(2-bromo-1-oxopropyl)amino]-4-methyl-, methyl ester
918-697-3 1160919-46-9 Active Intermediate Individual Intermediate use only 28-04-2017 View substance registered dossier
2-Thiophenecarboxylic acid, 3-[[(2-methoxy-2-oxoethyl)amino]sulfonyl]-, methyl ester
600-780-8 106820-63-7 Active Intermediate Joint Intermediate use only 24-02-2017 View substance registered dossier
2-Thiophenecarboxylic acid, 3-amino-2,5-dihydro-4-methyl-, methyl ester, 1-oxide
603-029-2 125088-75-7 Active Intermediate Joint Intermediate use only 01-02-2018 View substance registered dossier
2-Thiophenecarboxylic acid, 5-chloro-
480-060-6 24065-33-6 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
2-Thiophenemethanol, .alpha.-[2-(dimethylamino)ethyl]-
603-957-8 13636-02-7 Active Intermediate Individual Intermediate use only 28-11-2011 View substance registered dossier
2-Thiophenemethanol, .alpha.-[2-(dimethylamino)ethyl]-, (.alpha.S)-
603-565-7 132335-44-5 Active Intermediate Individual Intermediate use only 18-11-2011 View substance registered dossier
2-Thiophenemethanol, .alpha.-[2-(dimethylamino)ethyl]-, (.alpha.S)-
603-565-7 132335-44-5 Active Intermediate Individual Intermediate use only 19-02-2014 View substance registered dossier
2-Thiophenemethanol, .alpha.-[2-(methylamino)ethyl]-, (.alpha.S)-
601-437-5 116539-55-0 Active Intermediate Joint Intermediate use only 19-02-2019 View substance registered dossier
2-Thiophenepropanamine, N,N-dimethyl-.gamma.-(1-naphthalenyloxy)-, ethanedioate (1:1), (.gamma.S)-
603-567-8 132335-47-8 Active Intermediate Individual Intermediate use only 08-10-2009 View substance registered dossier
2-Thiophenepropanoic acid, .beta.-oxo-, methyl ester
603-835-4 134568-16-4 Active Intermediate Joint Intermediate use only 18-04-2017 View substance registered dossier
2-trifluoromethylphenothiazine
202-145-7 92-30-8 Active Intermediate Joint Intermediate use only 15-03-2018 View substance registered dossier
2-vinylpyridine
202-879-8 100-69-6 Active Intermediate Individual Intermediate use only 10-03-2015 View substance registered dossier
2-{2-[(2R,4R,6R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl]ethyl}-1H-isoindole-1,3(2H)-dione
700-188-0 1333481-90-5 Active Intermediate Joint Intermediate use only 06-04-2020 View substance registered dossier
2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl 4-methylbenzenesulfonate
606-467-2 202189-76-2 Active Intermediate Joint Intermediate use only 16-08-2021 View substance registered dossier
2-{5-[(dichlorophosphoryl)amino]-1,2,4-thiadiazol-3-yl}-(Z)-2-(ethoxyimino)acetyl chloride
ATDE-CL
448-000-3 90211-01-1 Active Intermediate Individual Intermediate use only 14-06-2011 View substance registered dossier
2-{5-[(dichlorophosphoryl)amino]-1,2,4-thiadiazol-3-yl}-(Z)-2-(ethoxyimino)acetyl chloride
ATDE-CL
448-000-3 90211-01-1 Active Intermediate Joint Intermediate use only 21-04-2021 View substance registered dossier
2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-[(dimethylamino)methyl]-5-(4-nitrophenyl)thiophene-3-carboxylic acid
854-550-9 1589503-95-6 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol (2R,3R)-2,3-dihydroxysuccinate
690-047-9 376608-65-0 Active Intermediate Joint Intermediate use only 02-04-2019 View substance registered dossier
2-{[2,2,4-trifluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}ethanol
700-535-6 1190931-34-0 Active Intermediate Individual Intermediate use only 05-02-2019 View substance registered dossier
20-oxopregna-5,16-dien-3-β-yl acetate
213-558-7 979-02-2 Active Intermediate Joint Intermediate use only 20-11-2020 View substance registered dossier
21-hydroxy-2'-methyl-16β-5'H-pregn-4-eno[17,16-d]oxazole-3,20-dione 21-acetate
244-306-4 21269-13-6 Active Intermediate Joint Intermediate use only 15-09-2017 View substance registered dossier
21-hydroxy-20-methylpregn-4-en-3-one
262-543-1 60966-36-1 Active Intermediate Joint Intermediate use only 14-01-2022 View substance registered dossier
21-hydroxypregna-1,4,9(11),16-tetraene-3,20-dione 21-acetate
253-497-3 37413-91-5 Active Intermediate Joint Intermediate use only 12-04-2021 View substance registered dossier
21-hydroxypregna-4,9(11),16-triene-3,20-dione 21-acetate
245-674-9 23460-76-6 Active Intermediate Joint Intermediate use only 24-04-2019 View substance registered dossier
2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one, 1,3,4,4a,5,6,6a,12,12a,12b-decahydro-3,6,12-trihydroxy-4-(hydroxymethyl)-4,6a,12b-trimethyl-9-(3-pyridinyl)-, (3S,4R,4aR,6S,6aS,12R,12aS,12bS)-
815-153-6 155850-27-4 Active Intermediate Joint Intermediate use only 23-11-2017 View substance registered dossier
2H-1,2-Benzothiazine-3-carboxylic acid, 4-hydroxy-, ethyl ester, 1,1-dioxide
607-417-2 24683-21-4 Active Intermediate Joint Intermediate use only 31-03-2022 View substance registered dossier
2H-1,3-benzoxazine-2,4(3H)-dione
606-541-4 2037-95-8 Active Intermediate Joint Intermediate use only 07-06-2021 View substance registered dossier
2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-
813-253-4 96576-92-0 Active Intermediate Individual Intermediate use only 30-11-2016 View substance registered dossier
2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)-
606-373-1 197706-50-6 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2R)-
603-315-7 129050-26-6 Active Intermediate Joint Intermediate use only 18-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active 2-pyrrolidin-1-ylethanol 220-976-3 2955-88-6 - View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active 2-pyrrolidin-1-ylethanol 220-976-3 2955-88-6 2017 View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active 2-Pyrrolidinone, 5-ethenyl- 616-206-4 7529-16-0 2009; 2010; 2012 View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active 2-pyrrolidone 210-483-1 616-45-5 - View substance registered dossier
[Confidential] - - - 2-Quinolinamine, 8-chloro-N-[4-(trihalomethoxy)aryl]-, halide - - - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 2-tBuPDI ligand - - - View substance registered dossier
Nagase (Europa) GmbH Werdener Straße 4 40227 Düsseldorf Germany Germany Active 2-tert-butoxyethanol 456-140-1 - - View substance registered dossier
SI Group France (FRAA), SAS 2 Chemin du Trou Bieuet 60840 Catenoy 60 France France Active 2-tert-butyl-p-cresol 219-314-6 2409-55-4 2012 View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active 2-tert-butyl-p-cresol 219-314-6 2409-55-4 2013 View substance registered dossier
SI Group Germany (DEAB) GmbH Teplitzer Strasse 14-16 84478 Waldkraiburg Germany Germany Active 2-tert-butyl-p-cresol 219-314-6 2409-55-4 2012 View substance registered dossier
Raschig GmbH Mundenheimerstraße 100 D-67061 Ludwigshafen Germany Germany Active 2-tert-butyl-p-cresol 219-314-6 2409-55-4 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 2-thenoic acid 208-423-4 527-72-0 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2-thenoic acid 208-423-4 527-72-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one 608-646-0 3159-07-7 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one 608-646-0 3159-07-7 - View substance registered dossier
MOEHS CANTABRA P.I.Requejada Z-23 39313 Polanco Cantabria Spain Spain Active 2-thia-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one 608-646-0 3159-07-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-thiazolidinylidenecyanamide 427-720-1 26364-65-8 2010 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active 2-thienylacetic acid 217-639-8 1918-77-0 2020 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 2-thienylacetic acid 217-639-8 1918-77-0 - View substance registered dossier
Kemikos s.r.l. Via Carolina Romani, 2/A 20091 Bresso (MI) Italy Italy Active 2-thienylacetic acid 217-639-8 1918-77-0 - View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active 2-thienylacetonitrile 244-104-6 20893-30-5 2021 View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active 2-thienylacetyl chloride 254-290-0 39098-97-0 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 2-thienylacetyl chloride 254-290-0 39098-97-0 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 2-thienylacetyl chloride 254-290-0 39098-97-0 - View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active 2-thienylacetyl chloride 254-290-0 39098-97-0 - View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active 2-thienylacetyl chloride 254-290-0 39098-97-0 2018 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active 2-thienylacetyl chloride 254-290-0 39098-97-0 2020 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 2-thienylcarbonyl chloride 226-092-4 5271-67-0 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active 2-thiobarbituric acid 207-985-8 504-17-6 2018 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 2-Thiopheneacetic acid, .alpha.-methyl- 611-216-5 54955-39-4 - View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 2-Thiopheneacetic acid, 5-benzoyl-.alpha.-methyl-, sodium salt (1:1) 923-143-9 59173-03-4 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2-Thiophenecarboxylic acid, 3-[(2-bromo-1-oxopropyl)amino]-4-methyl-, methyl ester 918-697-3 1160919-46-9 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 2-Thiophenecarboxylic acid, 3-[[(2-methoxy-2-oxoethyl)amino]sulfonyl]-, methyl ester 600-780-8 106820-63-7 2017 View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active 2-Thiophenecarboxylic acid, 3-amino-2,5-dihydro-4-methyl-, methyl ester, 1-oxide 603-029-2 125088-75-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-Thiophenecarboxylic acid, 5-chloro- 480-060-6 24065-33-6 2010; 2018 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 2-Thiophenecarboxylic acid, 5-chloro- 480-060-6 24065-33-6 - View substance registered dossier
SYNTESIA CHEMIE GmbH Martinistr. 13 20251 Hamburg Germany Germany Active 2-Thiophenemethanol, .alpha.-[2-(dimethylamino)ethyl]- 603-957-8 13636-02-7 - View substance registered dossier
SYNTESIA CHEMIE GmbH Martinistr. 13 20251 Hamburg Germany Germany Active 2-Thiophenemethanol, .alpha.-[2-(dimethylamino)ethyl]-, (.alpha.S)- 603-565-7 132335-44-5 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 2-Thiophenemethanol, .alpha.-[2-(dimethylamino)ethyl]-, (.alpha.S)- 603-565-7 132335-44-5 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active 2-Thiophenemethanol, .alpha.-[2-(methylamino)ethyl]-, (.alpha.S)- 601-437-5 116539-55-0 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 2-Thiophenemethanol, .alpha.-[2-(methylamino)ethyl]-, (.alpha.S)- 601-437-5 116539-55-0 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 2-Thiophenemethanol, .alpha.-[2-(methylamino)ethyl]-, (.alpha.S)- 601-437-5 116539-55-0 - View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active 2-Thiophenepropanamine, N,N-dimethyl-.gamma.-(1-naphthalenyloxy)-, ethanedioate (1:1), (.gamma.S)- 603-567-8 132335-47-8 2009 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 2-Thiophenepropanoic acid, .beta.-oxo-, methyl ester 603-835-4 134568-16-4 2010; 2017 View substance registered dossier
Trifarma S.p.A. Via G. Guarini Matteucci 1 20162 Milan (MI) Italy Italy Active 2-trifluoromethylphenothiazine 202-145-7 92-30-8 - View substance registered dossier
LABORATORIOS ESPINOS Y BOFILL S.A Ctra de l’Hospitalet, 34 08940 Cornellá Barcelona Spain Spain Active 2-vinylpyridine 202-879-8 100-69-6 - View substance registered dossier
Pfizer Ltd Ramsgate Road CT13 9NJ Sandwich Kent United Kingdom United Kingdom No longer Valid 2-{2-[(2R,4R,6R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl]ethyl}-1H-isoindole-1,3(2H)-dione 700-188-0 1333481-90-5 2021 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 2-{2-[(2R,4R,6R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl]ethyl}-1H-isoindole-1,3(2H)-dione 700-188-0 1333481-90-5 - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active 2-{2-[(2R,4R,6R)-4,6-dihydroxytetrahydro-2H-pyran-2-yl]ethyl}-1H-isoindole-1,3(2H)-dione 700-188-0 1333481-90-5 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active 2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl 4-methylbenzenesulfonate 606-467-2 202189-76-2 - View substance registered dossier
Faes Farma S.A. Máximo Aguirre 14 48940 Leioa Vizcaya Spain Spain Active 2-{4-[2-(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)propan-2-yl]phenyl}ethyl 4-methylbenzenesulfonate 606-467-2 202189-76-2 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 2-{5-[(dichlorophosphoryl)amino]-1,2,4-thiadiazol-3-yl}-(Z)-2-(ethoxyimino)acetyl chloride 448-000-3 90211-01-1 - View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active 2-{5-[(dichlorophosphoryl)amino]-1,2,4-thiadiazol-3-yl}-(Z)-2-(ethoxyimino)acetyl chloride 448-000-3 90211-01-1 - View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-[(dimethylamino)methyl]-5-(4-nitrophenyl)thiophene-3-carboxylic acid 854-550-9 1589503-95-6 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-[(dimethylamino)methyl]-5-(4-nitrophenyl)thiophene-3-carboxylic acid 854-550-9 1589503-95-6 2021 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol (2R,3R)-2,3-dihydroxysuccinate 690-047-9 376608-65-0 - View substance registered dossier
Solvay Specialty Polymers Italy S.p.A. Viale Lombardia 20 20021 BOLLATE Italy Italy Active 2-{[2,2,4-trifluoro-5-(trifluoromethoxy)-1,3-dioxolan-4-yl]oxy}ethanol 700-535-6 1190931-34-0 2016; 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 20-oxopregna-5,16-dien-3-β-yl acetate 213-558-7 979-02-2 - View substance registered dossier
Steroid SpA Viale Spagna 156 20093 Cologno Monzese Milano Italy Italy Active 20-oxopregna-5,16-dien-3-β-yl acetate 213-558-7 979-02-2 - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active 21-hydroxy-2'-methyl-16β-5'H-pregn-4-eno[17,16-d]oxazole-3,20-dione 21-acetate 244-306-4 21269-13-6 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active 21-hydroxy-20-methylpregn-4-en-3-one 262-543-1 60966-36-1 - View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active 21-hydroxy-20-methylpregn-4-en-3-one 262-543-1 60966-36-1 - View substance registered dossier
RSI ChemRep Europe Ltd (P001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active 21-hydroxypregna-1,4,9(11),16-tetraene-3,20-dione 21-acetate 253-497-3 37413-91-5 2021 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 21-hydroxypregna-1,4,9(11),16-tetraene-3,20-dione 21-acetate 253-497-3 37413-91-5 - View substance registered dossier
NEWCHEM S.P.A. VIA EDMONDO DE AMICIS 47 20123 MILANO ITALY Italy Italy Active 21-hydroxypregna-1,4,9(11),16-tetraene-3,20-dione 21-acetate 253-497-3 37413-91-5 - View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active 21-hydroxypregna-1,4,9(11),16-tetraene-3,20-dione 21-acetate 253-497-3 37413-91-5 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 21-hydroxypregna-4,9(11),16-triene-3,20-dione 21-acetate 245-674-9 23460-76-6 - View substance registered dossier
[Confidential] - - - 2H,11H-Naphtho[2,1-b]pyrano[3,4-e]pyran-11-one, 1,3,4,4a,5,6,6a,12,12a,12b-decahydro-3,6,12-trihydroxy-4-(hydroxymethyl)-4,6a,12b-trimethyl-9-(3-pyridinyl)-, (3S,4R,4aR,6S,6aS,12R,12aS,12bS)- 815-153-6 155850-27-4 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 2H-1,2-Benzothiazine-3-carboxylic acid, 4-hydroxy-, ethyl ester, 1,1-dioxide 607-417-2 24683-21-4 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1,3-benzoxazine-2,4(3H)-dione 606-541-4 2037-95-8 - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active 2H-1,3-benzoxazine-2,4(3H)-dione 606-541-4 2037-95-8 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 2H-1,4-Benzodiazepin-2-one, 3-(acetyloxy)-7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl- 813-253-4 96576-92-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2R)- 606-373-1 197706-50-6 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-, (2R)- 603-315-7 129050-26-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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