Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate
840-148-0 308831-94-9 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
Ethyl 3({2-[(4-cyanophenylamino)-methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}-pyridin-2-yl-amino)-propanoate hemifumarate
810-123-9 1428362-10-0 Active Intermediate Joint Intermediate use only 28-04-2016 View substance registered dossier
ethyl 3,3,3-trifluoro-2-oxopropanoate
603-440-7 13081-18-0 Active Intermediate Joint Intermediate use only 08-07-2020 View substance registered dossier
Ethyl 3,4-bis(2-methoxyethoxy)benzoate
605-991-9 183322-16-9 Cease Manufacture Intermediate Individual Cease manufacture 06-11-2012 View substance registered dossier
Ethyl 3,4-dihydroxybenzoate
223-529-0 3943-89-3 Cease Manufacture Intermediate Joint Cease manufacture 30-11-2015 View substance registered dossier
Ethyl 3,5-dichloro-4-hydroxybenzoate
241-331-2 17302-82-8 Active Intermediate Individual Intermediate use only 17-04-2018 View substance registered dossier
Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate
BIBR 1048 MANAMIDE
454-450-1 - Active Intermediate Individual Intermediate use only 17-08-2011 View substance registered dossier
Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate
BIBR 1048 MANAMIDE
454-450-1 - Active Intermediate Joint Intermediate use only 20-11-2019 View substance registered dossier
Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride
801-940-1 211914-50-0 Active Intermediate Joint Intermediate use only 21-02-2023 View substance registered dossier
Ethyl 3-(chloroformyl)propionate
238-855-9 14794-31-1 Active Intermediate Joint Intermediate use only 05-02-2018 View substance registered dossier
Ethyl 3-(diethylamino)propionate
226-859-3 5515-83-3 Active Intermediate Joint Intermediate use only 03-12-2014 View substance registered dossier
Ethyl 3-(triethoxysilyl)propylcarbamate
241-872-4 17945-05-0 Active Intermediate Joint Intermediate use only 30-01-2018 View substance registered dossier
ethyl 3-[(3R)-3-{[(1S)-1-phenylethyl]amino}-2,3,4,9-tetrahydro-1H-carbazol-9-yl]propanoate
811-937-7 1638586-33-0 Active Intermediate Joint Intermediate use only 15-03-2016 View substance registered dossier
Ethyl 3-[(5-chloro-2-nitrophenyl)phenylamino]-3-oxopropionate
244-907-1 22316-45-6 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
ethyl 3-[5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxyphenyl]-3-oxopropanoate
638-801-8 949465-81-0 Active Intermediate Individual Intermediate use only 10-11-2016 View substance registered dossier
Ethyl 3-amino-1H-pyrazole-4-carboxylate
230-262-3 6994-25-8 Active Intermediate Joint Intermediate use only 10-05-2013 View substance registered dossier
ethyl 3-amino-2-cyanoprop-2-enoate
609-521-3 38109-77-2 Active Intermediate Individual Intermediate use only 14-05-2013 View substance registered dossier
ethyl 3-amino-3-phenylpropanoate
613-206-6 6335-76-8 Active Intermediate Joint Intermediate use only 27-02-2017 View substance registered dossier
Ethyl 3-amino-4-[2-(phthalimido)ethoxy]crotonate
700-069-3 265136-65-0 Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
Ethyl 3-aminocrotonate
230-782-0 7318-00-5 Active Intermediate Joint Intermediate use only 11-12-2020 View substance registered dossier
Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate
610-491-9 500011-92-7 Active Intermediate Joint Intermediate use only 08-10-2020 View substance registered dossier
Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate
805-389-8 500011-91-6 Active Intermediate Joint Intermediate use only 21-09-2020 View substance registered dossier
Ethyl 3-chloro-3-oxopropionate
252-934-5 36239-09-5 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
Ethyl 3-difluoromethyl-1-methyl-4-pyrazole carboxylate
619-510-5 141573-95-7 Active Intermediate Individual Intermediate use only 13-04-2012 View substance registered dossier
Ethyl 3-ethoxy-3-iminopropionate hydrochloride
219-028-1 2318-25-4 Active Intermediate Joint Intermediate use only 11-05-2018 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate 840-148-0 308831-94-9 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active ethyl 2-{[(2,6-difluorophenyl)methyl](ethoxycarbonyl)amino}-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate 840-148-0 308831-94-9 2021 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active Ethyl 3({2-[(4-cyanophenylamino)-methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}-pyridin-2-yl-amino)-propanoate hemifumarate 810-123-9 1428362-10-0 2016 View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active ethyl 3,3,3-trifluoro-2-oxopropanoate 603-440-7 13081-18-0 2018; 2019; 2020 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active ethyl 3,3,3-trifluoro-2-oxopropanoate 603-440-7 13081-18-0 - View substance registered dossier
S.A. Ajinomoto OmniChem N.V. Industrial Research Park Fleming 1348 Louvain-la-Neuve Belgium Belgium Cease Manufacture Ethyl 3,4-bis(2-methoxyethoxy)benzoate 605-991-9 183322-16-9 2020 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture Ethyl 3,4-dihydroxybenzoate 223-529-0 3943-89-3 2018 View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active Ethyl 3,5-dichloro-4-hydroxybenzoate 241-331-2 17302-82-8 - View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate 454-450-1 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate 454-450-1 - 2015 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate 454-450-1 - 2012; 2013; 2014; 2019 View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride 801-940-1 211914-50-0 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride 801-940-1 211914-50-0 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active Ethyl 3-(chloroformyl)propionate 238-855-9 14794-31-1 - View substance registered dossier
SD Agchem (Europe) NV Uitbreidingstraat 84/3, 2600 Berchem, Belgium Belgium Belgium Active Ethyl 3-(chloroformyl)propionate 238-855-9 14794-31-1 - View substance registered dossier
A.C.R.A.F. Spa Via Amelia 70 00181 Roma Italy Italy Active Ethyl 3-(diethylamino)propionate 226-859-3 5515-83-3 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Ethyl 3-(triethoxysilyl)propylcarbamate 241-872-4 17945-05-0 2018 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active ethyl 3-[(3R)-3-{[(1S)-1-phenylethyl]amino}-2,3,4,9-tetrahydro-1H-carbazol-9-yl]propanoate 811-937-7 1638586-33-0 2016 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active Ethyl 3-[(5-chloro-2-nitrophenyl)phenylamino]-3-oxopropionate 244-907-1 22316-45-6 2021; 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Ethyl 3-[(5-chloro-2-nitrophenyl)phenylamino]-3-oxopropionate 244-907-1 22316-45-6 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active ethyl 3-[5-(3-chloro-2-fluorobenzyl)-2,4-dimethoxyphenyl]-3-oxopropanoate 638-801-8 949465-81-0 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active Ethyl 3-amino-1H-pyrazole-4-carboxylate 230-262-3 6994-25-8 - View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active Ethyl 3-amino-1H-pyrazole-4-carboxylate 230-262-3 6994-25-8 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active ethyl 3-amino-2-cyanoprop-2-enoate 609-521-3 38109-77-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active ethyl 3-amino-3-phenylpropanoate 613-206-6 6335-76-8 2017 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active Ethyl 3-amino-4-[2-(phthalimido)ethoxy]crotonate 700-069-3 265136-65-0 2010; 2012; 2015 View substance registered dossier
PCAS Finland Oy Messukentänkatu 8 20210 TURKU Finland Finland Active Ethyl 3-aminocrotonate 230-782-0 7318-00-5 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active Ethyl 3-aminocrotonate 230-782-0 7318-00-5 2020 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid Ethyl 3-aminocrotonate 230-782-0 7318-00-5 2021 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active Ethyl 3-aminocrotonate 230-782-0 7318-00-5 - View substance registered dossier
[Confidential] - - - Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate 610-491-9 500011-92-7 - View substance registered dossier
[Confidential] - - - Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate 805-389-8 500011-91-6 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active Ethyl 3-chloro-3-oxopropionate 252-934-5 36239-09-5 2021; 2022 View substance registered dossier
M2I SALIN 112 bureaux de la colline 92213 St Cloud France France Active Ethyl 3-difluoromethyl-1-methyl-4-pyrazole carboxylate 619-510-5 141573-95-7 2012 View substance registered dossier
CHEMI S.p.A. Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy Italy Active Ethyl 3-ethoxy-3-iminopropionate hydrochloride 219-028-1 2318-25-4 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.