Registered substances

Registered substances

Registered substances

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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1-[3-(Hydroxymethyl)pyridin-2-yl)-4-methyl-2-phenylpiperazine
700-296-8 61337-89-1 Active Intermediate Individual Intermediate use only 29-01-2009 View substance registered dossier
1-[3,5-bis(benzyloxy)phenyl]-2-bromoethanone - 1,4-dioxane (2:1)
944-082-4 - Active Intermediate Individual Intermediate use only 21-05-2019 View substance registered dossier
1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione
687-893-6 1150560-54-5 Active Intermediate Joint Intermediate use only 04-02-2021 View substance registered dossier
1-[2-[[4-[2-[2-amino-5-hydroxy-6-[2-[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-7-sulfo-1-naphthalenyl]diazenyl]-3-sulfophenyl]sulfonyl]ethyl]-pyrimidinium-3-carboxylic acid mono-, di- and trisodium salts
483-940-8 - Active Full Joint ≥ 1 tonnes 18-01-2021 View substance registered dossier
1-[2-[[4-[(2-chloro-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]pyridinium acetate
261-873-3 59709-10-3 Active Full Joint ≥ 10 to < 100 tonnes 27-03-2020 View substance registered dossier
1-[2-[(S)-(4-Chlorophenyl)phenylmethoxy]ethyl]piperidine hydrochloride
606-899-1 220282-83-7 Active Intermediate Individual Intermediate use only 12-12-2017 View substance registered dossier
1-[2-[(5-chloro-2,1,3-benzothiadiazol-4-yl)amino]-4,5-dihydroimidazol-1-yl]ethanone
605-682-9 173532-15-5 Active Intermediate Joint Intermediate use only 03-08-2018 View substance registered dossier
1-[2-(dimethylamino)-1-(4-phenylmethoxyphenyl)ethyl]cyclohexan-1-ol
618-943-7 93413-61-7 Active Intermediate Joint Intermediate use only 04-03-2019 View substance registered dossier
1-[2-(Amino)-1-(4-hydroxyphenyl)ehtyl]cyclohexanol
812-270-4 149289-29-2 Active Intermediate Joint Intermediate use only 01-04-2021 View substance registered dossier
1-[2-(allyloxy)ethyl-2-(2,4-dichlorophenyl)-1H-imidazolium hydrogen sulphate
261-351-5 58594-72-2 Active Full Joint ≥ 10 to < 100 tonnes 13-12-2019 View substance registered dossier
1-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-imidazole mononitrate
246-039-9 24155-29-1 Active Intermediate Joint Intermediate use only 23-01-2018 View substance registered dossier
1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]ethan-1-one
278-549-2 76784-40-2 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]-2,2,2-trichloroethan-1-one
278-550-8 76784-42-4 Active Intermediate Joint Intermediate use only 04-05-2020 View substance registered dossier
1-[2,3-dihydro-1,1,2,6-tetramethyl-3-(1-methylethyl)-1H-inden-5-yl]ethan-1-one
268-799-0 68140-48-7 Active Full Joint ≥ 1 to < 10 tonnes 30-05-2018 View substance registered dossier
1-[1,6-dimethyl-4-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one
260-772-1 57499-57-7 Active Intermediate Joint Intermediate use only 29-05-2013 View substance registered dossier
1-[1,6-dimethyl-4-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one
260-772-1 57499-57-7 Active Intermediate Joint Intermediate use only 23-05-2018 View substance registered dossier
1-[1,6-dimethyl-3-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one
259-173-8 54464-54-9 Active Intermediate Joint Intermediate use only 16-08-2010 View substance registered dossier
1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea
278-928-2 78491-02-8 Active Full Joint ≥ 100 to < 1 000 tonnes 01-12-2020 View substance registered dossier
1-[(tert-butoxycarbonyl)amino]cyclobutane-1-carboxylic acid
627-199-2 120728-10-1 Active Intermediate Joint Intermediate use only 19-11-2020 View substance registered dossier
1-[(E)-(2-Chlorophenyl)(methylimino)methyl]cyclopentanol
641-894-8 6740-87-0 Active Full Joint ≥ 0 to < 10 tonnes 12-02-2019 View substance registered dossier
1-[([[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl)oxy]pyrrolidine-2,5-dione
813-811-7 253265-97-3 Active Full Joint ≥ 10 to < 100 tonnes 23-06-2020 View substance registered dossier
1-[(7S)-4,7-dihydro-5H-thieno[2,3-c]pyran-7-yl]-N-methylmethanamine (2R)
850-249-1 2374784-46-8 Active Intermediate Joint Intermediate use only 28-08-2020 View substance registered dossier
1-[(5α,7α)-4,5-epoxy-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone
239-393-0 15358-22-2 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone
240-326-2 16196-82-0 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
1-[(4-methoxy-2-nitrophenyl)azo]-2-naphthol
256-458-9 49744-28-7 Active Full Joint ≥ 1 to < 10 tonnes 22-01-2018 View substance registered dossier
1-[(4-chlorophenyl)sulfanyl]propan-2-one
607-811-4 25784-83-2 Active Full Joint ≥ 1 to < 10 tonnes 03-05-2019 View substance registered dossier
1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline
230-148-3 6957-27-3 Active Intermediate Joint Intermediate use only 28-06-2016 View substance registered dossier
1-[(3,3-diphenylpropyl)(methyl)amino]-2-methyl-2-propanol
700-254-9 100442-33-9 Active Intermediate Individual Intermediate use only 29-09-2015 View substance registered dossier
1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-N-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}hydrazine-1-carboxamide
447-870-1 - Active Intermediate Joint Intermediate use only 24-03-2021 View substance registered dossier
1-[(2S)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone
700-605-6 1333469-32-1 Active Intermediate Individual Intermediate use only 15-06-2011 View substance registered dossier
1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine
601-832-2 122151-32-0 Active Intermediate Individual Intermediate use only 08-02-2018 View substance registered dossier
1-[(2R)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone
700-612-4 1333469-23-0 Active Intermediate Individual Intermediate use only 15-06-2011 View substance registered dossier
1-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]pyrrolidine-2,5-dione
700-068-8 103953-71-5 Active Intermediate Individual Intermediate use only 28-10-2008 View substance registered dossier
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol
AMBER CORE
412-300-2 139504-68-0 Active Full Joint ≥ 100 to < 1 000 tonnes 28-12-2021 View substance registered dossier
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol
AMBER CORE
412-300-2 139504-68-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-[(2-methyl-1H-imidazol-1-yl)methyl]-2-naphthol
428-170-5 185554-99-8 Active NONS Joint Tonnage data confidential 18-10-2010 View substance registered dossier
1-[(2-methoxyphenyl)azo]-2-naphthol
214-968-9 1229-55-6 Active Full Joint ≥ 1 to < 10 tonnes 01-06-2017 View substance registered dossier
1-[(2-hydroxyethyl)thio]propan-2-ol
229-765-0 6713-03-7 Active Full Joint ≥ 10 to < 100 tonnes 12-04-2018 View substance registered dossier
1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphthol
229-214-4 6434-57-7 Active Intermediate Joint Intermediate use only 15-03-2018 View substance registered dossier
1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile
849-893-6 256376-65-5 Active Intermediate Individual Intermediate use only 17-07-2020 View substance registered dossier
1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol
220-562-2 2814-77-9 Active Full Joint ≥ 100 to < 1 000 tonnes 17-12-2020 View substance registered dossier
1-[(2-butyloctyl)oxy]-3-(3,4-dihydroisoquinolinium-2-yl)propan-2-yl sulfate
470-080-3 - Active Full Individual ≥ 10 to < 100 tonnes 10-05-2011 View substance registered dossier
1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione—hydrogen chloride (1/1)
858-184-0 1589503-99-0 Active Intermediate Joint Intermediate use only 08-03-2021 View substance registered dossier
1-[(2,4-dinitrophenyl)azo]-2-naphthol
222-429-4 3468-63-1 Active Full Joint ≥ 100 to < 1 000 tonnes 16-03-2022 View substance registered dossier
1-[(1Ξ,2Ξ)-2-Chloro-1-hydroxy-3-(quinolin-6-yl)propyl]pyrrolidine-2,5-dione
811-462-5 1197377-31-3 Active Intermediate Individual Intermediate use only 16-10-2018 View substance registered dossier
1-3 dihydroxy-2,4bis-(4-(2-sulfooxyethanesulfonyl)-phenylazo) benzene disodium salt
937-924-7 - Active Full Joint ≥ 1 to < 10 tonnes 23-04-2018 View substance registered dossier
1-(β-phenethyl)-4-piperidone
254-613-5 39742-60-4 Active Intermediate Joint Intermediate use only 20-08-2019 View substance registered dossier
1-({[(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methyl]sulfonyl}oxy)pyrrolidine-2,5-dione
428-080-6 - Active NONS Joint Tonnage data confidential 27-11-2012 View substance registered dossier
1-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}oxy)ethyl 2-methylpropanoate
700-402-2 860035-10-5 Cease Manufacture Intermediate Joint Cease manufacture 04-06-2020 View substance registered dossier
1-(vinyloxy)propane
212-123-9 764-47-6 Active Intermediate Joint Intermediate use only 13-11-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 1-[3-(Hydroxymethyl)pyridin-2-yl)-4-methyl-2-phenylpiperazine 700-296-8 61337-89-1 - View substance registered dossier
AstraZeneca B 313:5 AZ GlobalSHE- Chem.Reg. 15185 Södertälje Sweden Sweden Active 1-[3,5-bis(benzyloxy)phenyl]-2-bromoethanone - 1,4-dioxane (2:1) 944-082-4 - 2019 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione 687-893-6 1150560-54-5 2021 View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active 1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione 687-893-6 1150560-54-5 - View substance registered dossier
Everlight Europe B.V. Rivium Boulevard 224 2909LK Capelle a/d Ijssel Netherlands Netherlands Active 1-[2-[[4-[2-[2-amino-5-hydroxy-6-[2-[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-7-sulfo-1-naphthalenyl]diazenyl]-3-sulfophenyl]sulfonyl]ethyl]-pyrimidinium-3-carboxylic acid mono-, di- and trisodium salts 483-940-8 - 2010; 2014; 2017; 2019; 2020; 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 1-[2-[[4-[2-[2-amino-5-hydroxy-6-[2-[2-methoxy-5-methyl-4-[[2-(sulfooxy)ethyl]sulfonyl]phenyl]diazenyl]-7-sulfo-1-naphthalenyl]diazenyl]-3-sulfophenyl]sulfonyl]ethyl]-pyrimidinium-3-carboxylic acid mono-, di- and trisodium salts 483-940-8 - - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 1-[2-[[4-[(2-chloro-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]pyridinium acetate 261-873-3 59709-10-3 - View substance registered dossier
Reach & Colours s.r.o Thunovská 196/19 Malá Strana 118 00 Prague Czech Republic Czech Republic Active 1-[2-[[4-[(2-chloro-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]pyridinium acetate 261-873-3 59709-10-3 - View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active 1-[2-[[4-[(2-chloro-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]pyridinium acetate 261-873-3 59709-10-3 2020 View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active 1-[2-[[4-[(2-chloro-4-nitrophenyl)azo]phenyl]ethylamino]ethyl]pyridinium acetate 261-873-3 59709-10-3 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active 1-[2-[(S)-(4-Chlorophenyl)phenylmethoxy]ethyl]piperidine hydrochloride 606-899-1 220282-83-7 - View substance registered dossier
FARMAK, a.s. Na vlcinci 16/3 779 00 Olomouc Czech Republic Czech Republic Active 1-[2-[(5-chloro-2,1,3-benzothiadiazol-4-yl)amino]-4,5-dihydroimidazol-1-yl]ethanone 605-682-9 173532-15-5 2018 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 1-[2-(dimethylamino)-1-(4-phenylmethoxyphenyl)ethyl]cyclohexan-1-ol 618-943-7 93413-61-7 2019 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 1-[2-(Amino)-1-(4-hydroxyphenyl)ehtyl]cyclohexanol 812-270-4 149289-29-2 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 1-[2-(allyloxy)ethyl-2-(2,4-dichlorophenyl)-1H-imidazolium hydrogen sulphate 261-351-5 58594-72-2 2019 View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 1-[2-(2,4-dichlorophenyl)-2-oxoethyl]-1H-imidazole mononitrate 246-039-9 24155-29-1 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]ethan-1-one 278-549-2 76784-40-2 - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 1-[2,5-bis(2,2,2-trifluoroethoxy)phenyl]-2,2,2-trichloroethan-1-one 278-550-8 76784-42-4 2020 View substance registered dossier
Givaudan France SAS - OR2 55, Rue de la voie des Bans 95102 Argenteuil Cedex France France Active 1-[2,3-dihydro-1,1,2,6-tetramethyl-3-(1-methylethyl)-1H-inden-5-yl]ethan-1-one 268-799-0 68140-48-7 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active 1-[2,3-dihydro-1,1,2,6-tetramethyl-3-(1-methylethyl)-1H-inden-5-yl]ethan-1-one 268-799-0 68140-48-7 - View substance registered dossier
Symrise Granada, S.A.U. Crta. Armilla Km 2, 5 18100 Armilla Granada Spain Spain Active 1-[1,6-dimethyl-4-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one 260-772-1 57499-57-7 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active 1-[1,6-dimethyl-4-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one 260-772-1 57499-57-7 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active 1-[1,6-dimethyl-4-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one 260-772-1 57499-57-7 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1-[1,6-dimethyl-3-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one 259-173-8 54464-54-9 - View substance registered dossier
Akema s.r.l. Via Puglie 12 47853 Coriano RN Italy Italy Active 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea 278-928-2 78491-02-8 2020 View substance registered dossier
Cyber Clean Europe GmbH Enzianstraße 6 82319 Starnberg Germany Germany Active 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea 278-928-2 78491-02-8 2019 View substance registered dossier
Beckman Coulter GmbH Europark Fichtenhain B13 47807 Krefeld Germany Germany Active 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea 278-928-2 78491-02-8 2018 View substance registered dossier
Schuelke & Mayr GmbH Robert-Koch-Str. 2 22851 Norderstedt Germany Germany Active 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea 278-928-2 78491-02-8 2018 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea 278-928-2 78491-02-8 2019 View substance registered dossier
3V Sigma S.p.A Torquato Tasso 58 24121 Bergamo Italy Italy Active 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea 278-928-2 78491-02-8 2018 View substance registered dossier
Ashland Services BV (OR2) Noordweg 9 3336 LH Zwijndrecht Netherlands Netherlands Active 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea 278-928-2 78491-02-8 2014 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1-[(tert-butoxycarbonyl)amino]cyclobutane-1-carboxylic acid 627-199-2 120728-10-1 2020 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 1-[(E)-(2-Chlorophenyl)(methylimino)methyl]cyclopentanol 641-894-8 6740-87-0 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active 1-[([[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl)oxy]pyrrolidine-2,5-dione 813-811-7 253265-97-3 2019; 2020 View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 1-[([[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy]carbonyl)oxy]pyrrolidine-2,5-dione 813-811-7 253265-97-3 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1-[(7S)-4,7-dihydro-5H-thieno[2,3-c]pyran-7-yl]-N-methylmethanamine (2R) 850-249-1 2374784-46-8 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid 1-[(5α,7α)-4,5-epoxy-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone 239-393-0 15358-22-2 2021 View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active 1-[(5α,7α)-4,5-epoxy-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone 239-393-0 15358-22-2 2018 View substance registered dossier
Indivior UK Ltd Henry Boot Way HU4 7DY Hull United Kingdom United Kingdom No longer Valid 1-[(5α,7α)-4,5-epoxy-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone 239-393-0 15358-22-2 2021 View substance registered dossier
Indivior UK Ltd Henry Boot Way HU4 7DY Hull United Kingdom United Kingdom No longer Valid 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone 240-326-2 16196-82-0 2021 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone 240-326-2 16196-82-0 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone 240-326-2 16196-82-0 2021 View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone 240-326-2 16196-82-0 2018 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 1-[(4-methoxy-2-nitrophenyl)azo]-2-naphthol 256-458-9 49744-28-7 - View substance registered dossier
[Confidential] - - - 1-[(4-chlorophenyl)sulfanyl]propan-2-one 607-811-4 25784-83-2 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline 230-148-3 6957-27-3 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 1-[(3,3-diphenylpropyl)(methyl)amino]-2-methyl-2-propanol 700-254-9 100442-33-9 2010; 2015 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active 1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-N-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}hydrazine-1-carboxamide 447-870-1 - 2019; 2021 View substance registered dossier
[Confidential] - - - 1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-N-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}hydrazine-1-carboxamide 447-870-1 - - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active 1-[(2S)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone 700-605-6 1333469-32-1 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active 1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine 601-832-2 122151-32-0 - View substance registered dossier
Reuter Chemische Apparatebau e.K. Engesserstrasse 4b 79108 Freiburg Germany Germany Active 1-[(2R)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone 700-612-4 1333469-23-0 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]pyrrolidine-2,5-dione 700-068-8 103953-71-5 - View substance registered dossier
Kao Chemicals Europe, S.L. (2) Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 2010; 2011; 2012; 2013; 2020; 2021 View substance registered dossier
Intertek Deutschland GmbH IEFC* Stangenstr.1 70771 Leinfelden-Echterdingen Germany Germany Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 2020 View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-[(2-methyl-1H-imidazol-1-yl)methyl]-2-naphthol 428-170-5 185554-99-8 - View substance registered dossier
Huntsman Advanced Materials (Spain) SL Avda de Arostegui s/n Apartado 94 E-31009 Pamplona Spain Spain Active 1-[(2-methyl-1H-imidazol-1-yl)methyl]-2-naphthol 428-170-5 185554-99-8 2010 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 1-[(2-methoxyphenyl)azo]-2-naphthol 214-968-9 1229-55-6 - View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active 1-[(2-hydroxyethyl)thio]propan-2-ol 229-765-0 6713-03-7 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphthol 229-214-4 6434-57-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile 849-893-6 256376-65-5 - View substance registered dossier
Sun Chemical B.V. Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands Netherlands No longer Valid 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 2016 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 2018 View substance registered dossier
DCL Corporation (NL) B.V. OR Sortieweg 39 6219 NT Maastricht Netherlands Netherlands Active 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 - View substance registered dossier
Sun Chemical B.V. Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands Netherlands Active 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 - View substance registered dossier
SpetsInterProject_Pigment Näkinkaari 1 M 02320 Espoo Finland Finland Cease Manufacture 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 2019 View substance registered dossier
Sudarshan Europe B.V. Kingsfordweg 151 1043 GR Amsterdam Noord-Holland Netherlands Netherlands Active 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 2016; 2017; 2020 View substance registered dossier
Clariant SE - IN02 Am Unisyspark 1 65843 Sulzbach am Taunus Germany Germany Active 1-[(2-chloro-4-nitrophenyl)azo]-2-naphthol 220-562-2 2814-77-9 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1-[(2-butyloctyl)oxy]-3-(3,4-dihydroisoquinolinium-2-yl)propan-2-yl sulfate 470-080-3 - 2011 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione—hydrogen chloride (1/1) 858-184-0 1589503-99-0 2021 View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione—hydrogen chloride (1/1) 858-184-0 1589503-99-0 - View substance registered dossier
Colorants Solutions Deutschland GmbH - BR01 Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
Daicolor Italy OR Via Vittor Pisani 28 20124 Milano Italy Italy Cease Manufacture 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 2019 View substance registered dossier
Only representative (No publishable name) - - Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
PNC PIGMENTS LLC Københavnsvej 112 4600 Køge Denmark Denmark Cease Manufacture 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 2016 View substance registered dossier
DyStar Anilinas Texteis, Unipessoal Lda. Rua Engº Ferreira Dias, 728 Salas 2-4 4100-246 Porto Portugal Portugal Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 2021 View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 2013; 2016 View substance registered dossier
Trust Chem Europe B.V. Bergpoortstraat 65 NL-7411 CL Deventer Netherlands Netherlands Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
Gustav Grolman GmbH & Co. KG Fuggerstr. 1 41468 Neuss Germany Germany Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
Daicolor Italy S.R.L. Via Vittor Pisani 28 20124 Milano Italy Italy Cease Manufacture 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 2019 View substance registered dossier
Sun Chemical B.V. Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands Netherlands Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 2013; 2017; 2019; 2022 View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
Hercules Pigments Pvt Ltd (represented by Luxcontrol S.A.) 1, Avenue des Terres Rouges 4331 Esch sur Alzette Luxembourg Luxembourg Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
Nitsu Chemicals LLP (represented by Luxcontrol S.A.) 1, Avenue des Terres Rouges 4331 Esch sur Alzette Luxembourg Luxembourg Active 1-[(2,4-dinitrophenyl)azo]-2-naphthol 222-429-4 3468-63-1 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active 1-[(1Ξ,2Ξ)-2-Chloro-1-hydroxy-3-(quinolin-6-yl)propyl]pyrrolidine-2,5-dione 811-462-5 1197377-31-3 - View substance registered dossier
BLENDWELL SA rue Benoît, 50 Zoning Industriel B-7370 Dour Belgium Belgium Active 1-3 dihydroxy-2,4bis-(4-(2-sulfooxyethanesulfonyl)-phenylazo) benzene disodium salt 937-924-7 - 2018 View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 1-(β-phenethyl)-4-piperidone 254-613-5 39742-60-4 - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Cease Manufacture 1-(β-phenethyl)-4-piperidone 254-613-5 39742-60-4 2019 View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active 1-(β-phenethyl)-4-piperidone 254-613-5 39742-60-4 - View substance registered dossier
Arevipharma GmbH Meißner Straße 35 01445 Radebeul Saxony Germany Germany Active 1-(β-phenethyl)-4-piperidone 254-613-5 39742-60-4 - View substance registered dossier
- - - - 1-({[(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methyl]sulfonyl}oxy)pyrrolidine-2,5-dione 428-080-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1-({[(7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methyl]sulfonyl}oxy)pyrrolidine-2,5-dione 428-080-6 - - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 1-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}oxy)ethyl 2-methylpropanoate 700-402-2 860035-10-5 2021 View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Cease Manufacture 1-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}oxy)ethyl 2-methylpropanoate 700-402-2 860035-10-5 2021 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 1-(vinyloxy)propane 212-123-9 764-47-6 2020 View substance registered dossier
CellMark Deutschland GmbH Hamborner Straße 53 D - 40547 Düsseldorf Germany Germany Germany Active 1-(vinyloxy)propane 212-123-9 764-47-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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