Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene
242-582-0 18794-84-8 Active Full Joint ≥ 100 to < 1 000 tonnes 13-07-2021 View substance registered dossier
methyl {[5-acetylamino-4-(2-chloro-4-nitrophenylazo)phenyl]ethoxycarbonylmethylamino}acetate;reaction mass of: methyl {[5-acetylamino-4-(2-chloro-4-nitrophenylazo)phenyl]methoxycarbonylmethylamino}acetate
424-290-7 188070-47-5 Active NONS Joint Tonnage data confidential 11-02-2022 View substance registered dossier
(R)-(−)-3-Amino-1-Boc-piperidine
628-472-9 188111-79-7 Active Intermediate Joint Intermediate use only 12-01-2022 View substance registered dossier
7-chloro-1,3-dihydro-1-methyl-5-phenyl-2-oxo-2H-1,4-benzodiazepin-3-yl acetate
242-597-2 18818-64-9 Active Intermediate Joint Intermediate use only 21-09-2017 View substance registered dossier
Spiro[bicyclo[2.2.1]heptane-2,4'-[1,3]dioxane], 1,7,7-trimethyl-2'-(1-methylethyl)-, (1R,2S,2'S,4R)-
443-460-1 188199-50-0 Active Full Joint ≥ 1 tonnes 05-07-2012 View substance registered dossier
Benzoic acid, 5-methoxy-2-nitro-
606-135-7 1882-69-5 Active Intermediate Joint Intermediate use only 01-12-2016 View substance registered dossier
17-α-hydroxypregn-4-ene-3,11,20-trione
217-541-5 1882-82-2 Active Intermediate Joint Intermediate use only 07-11-2017 View substance registered dossier
Manganese sulphide
242-599-3 18820-29-6 Active Full Joint ≥ 100 to < 1 000 tonnes 30-05-2018 View substance registered dossier
Pyridinium bromide
242-600-7 18820-82-1 Active Intermediate Joint Intermediate use only 11-05-2017 View substance registered dossier
Dipotassium 3,4,5,6-tetrabromophthalate
242-604-9 18824-74-3 Active Full Joint ≥ 10 to < 100 tonnes 09-04-2020 View substance registered dossier
trans,trans-2,3',4',5'-Tetrafluor-4-(4'-propylbicyclohexyl-4 -yl)-biphenyl
606-136-2 188289-44-3 Active Full Joint ≥ 0 to < 10 tonnes 05-04-2018 View substance registered dossier
Hexacos-1-ene
242-615-9 18835-33-1 No longer Valid Full Joint No longer valid 20-09-2010 View substance registered dossier
Hexacos-1-ene
242-615-9 18835-33-1 Active Intermediate Joint Intermediate use only 12-12-2019 View substance registered dossier
Octacos-1-ene
242-616-4 18835-34-2 No longer Valid Full Joint No longer valid 20-09-2010 View substance registered dossier
Octacos-1-ene
242-616-4 18835-34-2 Active Intermediate Joint Intermediate use only 12-12-2019 View substance registered dossier
1,3-Dioxepin, 4,7-dihydro-2-(1,1,4-trimethyl-3-penten-1-yl)-
480-360-7 188357-49-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,4-Decadienamide, N-(2-methylpropyl)-, (2E,4E)-
457-600-4 18836-52-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1)
639-694-0 188416-20-8 Cease Manufacture Intermediate Individual Cease manufacture 17-12-2010 View substance registered dossier
4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1)
639-694-0 188416-20-8 Active Intermediate Joint Intermediate use only 04-05-2015 View substance registered dossier
4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1)
928-729-8 188416-20-8 Active Intermediate Joint Intermediate use only 24-04-2013 View substance registered dossier
Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1R,4S)-, compd. with rel-(.alpha.R,.beta.S)-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol (1:1)
917-473-2 188416-34-4 Active Intermediate Joint Intermediate use only 16-04-2013 View substance registered dossier
Propanoic acid, 2-methyl-, 2-ethoxy-4-formylphenyl ester
444-930-9 188417-26-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N,N'-bis{N-[N-(4-chlorophenyl)carbamimidoyl]carbamimidoyl}hexane-1,6-bis(aminium) diundec-10-enoate
813-944-0 1884575-91-0 Active Full Joint ≥ 0 to < 10 tonnes 21-02-2021 View substance registered dossier
Phenyl chloroformate
217-547-8 1885-14-9 Active Intermediate Joint Intermediate use only 08-07-2020 View substance registered dossier
Anthranilonitrile
217-549-9 1885-29-6 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Grenzach-OR19 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Baden-Württemberg Germany Germany Active (E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 - View substance registered dossier
Penman Consulting bvba 07 Avenue des Arts 10 B-1210 Brussels Belgium Belgium Cease Manufacture (E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 2022 View substance registered dossier
Kuraray Europe GmbH (OR1) Philipp-Reis-Str. 4 65795 Hattersheim Germany Germany Active (E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 - View substance registered dossier
Penman Consulting bvba 06 Avenue des Arts 10 B-1210 Brussels Belgium Belgium Cease Manufacture (E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 2022 View substance registered dossier
ANTIBIOTICOS DE LEON S.L. Avda. Antibióticos, 59 - 61 24009 León Spain Spain Active (E)-7,11-dimethyl-3-methylenedodeca-1,6,10-triene 242-582-0 18794-84-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active methyl {[5-acetylamino-4-(2-chloro-4-nitrophenylazo)phenyl]ethoxycarbonylmethylamino}acetate;reaction mass of: methyl {[5-acetylamino-4-(2-chloro-4-nitrophenylazo)phenyl]methoxycarbonylmethylamino}acetate 424-290-7 188070-47-5 - View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active methyl {[5-acetylamino-4-(2-chloro-4-nitrophenylazo)phenyl]ethoxycarbonylmethylamino}acetate;reaction mass of: methyl {[5-acetylamino-4-(2-chloro-4-nitrophenylazo)phenyl]methoxycarbonylmethylamino}acetate 424-290-7 188070-47-5 2010; 2022 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (R)-(−)-3-Amino-1-Boc-piperidine 628-472-9 188111-79-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2-oxo-2H-1,4-benzodiazepin-3-yl acetate 242-597-2 18818-64-9 - View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2-oxo-2H-1,4-benzodiazepin-3-yl acetate 242-597-2 18818-64-9 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active Spiro[bicyclo[2.2.1]heptane-2,4'-[1,3]dioxane], 1,7,7-trimethyl-2'-(1-methylethyl)-, (1R,2S,2'S,4R)- 443-460-1 188199-50-0 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Spiro[bicyclo[2.2.1]heptane-2,4'-[1,3]dioxane], 1,7,7-trimethyl-2'-(1-methylethyl)-, (1R,2S,2'S,4R)- 443-460-1 188199-50-0 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Benzoic acid, 5-methoxy-2-nitro- 606-135-7 1882-69-5 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 17-α-hydroxypregn-4-ene-3,11,20-trione 217-541-5 1882-82-2 - View substance registered dossier
Tribotecc GmbH Industriestrasse 23 A-9601 Arnoldstein Austria Austria Active Manganese sulphide 242-599-3 18820-29-6 - View substance registered dossier
Satyam Europe B.V. Neringstaat-West 3 5401GB Uden Netherlands Netherlands Active Manganese sulphide 242-599-3 18820-29-6 - View substance registered dossier
Hoeganaes Corporation Europe S.A. 33 Urziceni Street 120226 Buzau Buzau Romania Romania Active Manganese sulphide 242-599-3 18820-29-6 - View substance registered dossier
Rio Tinto Iron and Titanium GmbH (2) Alfred-Herrhausen-Allee 3-5 65760 Eschborn Germany Germany Active Manganese sulphide 242-599-3 18820-29-6 - View substance registered dossier
Höganäs Sweden AB Bruksgatan 26383 Höganäs Sweden Sweden Active Manganese sulphide 242-599-3 18820-29-6 2016 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active Pyridinium bromide 242-600-7 18820-82-1 - View substance registered dossier
Stewardship Chemicals 55 Długosza 67 43-188 Orzesze Poland Poland Active Dipotassium 3,4,5,6-tetrabromophthalate 242-604-9 18824-74-3 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active trans,trans-2,3',4',5'-Tetrafluor-4-(4'-propylbicyclohexyl-4 -yl)-biphenyl 606-136-2 188289-44-3 - View substance registered dossier
Chevron Phillips Chemicals International N.V. - OR CPC Airport Plaza, Stockholm Building Da Vincilaan 19 1831 Diegem Belgium Belgium No longer Valid Hexacos-1-ene 242-615-9 18835-33-1 2011 View substance registered dossier
Chemours Netherlands B.V. Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Active Hexacos-1-ene 242-615-9 18835-33-1 - View substance registered dossier
Chevron Phillips Chemicals International N.V. - OR CPC Airport Plaza, Stockholm Building Da Vincilaan 19 1831 Diegem Belgium Belgium No longer Valid Octacos-1-ene 242-616-4 18835-34-2 2011 View substance registered dossier
Chemours Netherlands B.V. Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Active Octacos-1-ene 242-616-4 18835-34-2 - View substance registered dossier
- - - - 1,3-Dioxepin, 4,7-dihydro-2-(1,1,4-trimethyl-3-penten-1-yl)- 480-360-7 188357-49-5 - View substance registered dossier
- - - - 2,4-Decadienamide, N-(2-methylpropyl)-, (2E,4E)- 457-600-4 18836-52-7 - View substance registered dossier
Medichem Manufacturing (Malta) Limited HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta Malta Cease Manufacture 4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1) 639-694-0 188416-20-8 2017 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active 4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1) 639-694-0 188416-20-8 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1) 928-729-8 188416-20-8 2013 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active Bicyclo[2.2.1]heptane-1-methanesulfonic acid, 7,7-dimethyl-2-oxo-, (1R,4S)-, compd. with rel-(.alpha.R,.beta.S)-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol (1:1) 917-473-2 188416-34-4 2011; 2013 View substance registered dossier
- - - - Propanoic acid, 2-methyl-, 2-ethoxy-4-formylphenyl ester 444-930-9 188417-26-7 - View substance registered dossier
PHARMEGIC HEALTHCARE LIMITED Konstitucijos av. 21A, 08130 Vilnius Lithuania Ireland Ireland Active N,N'-bis{N-[N-(4-chlorophenyl)carbamimidoyl]carbamimidoyl}hexane-1,6-bis(aminium) diundec-10-enoate 813-944-0 1884575-91-0 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active Phenyl chloroformate 217-547-8 1885-14-9 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active Phenyl chloroformate 217-547-8 1885-14-9 2013; 2020 View substance registered dossier
INTERTEK FRANCE ZAC Ecoparc II 27400 HEUDEBOUVILLE France France Active Phenyl chloroformate 217-547-8 1885-14-9 - View substance registered dossier
FRAMOCHEM Szerviz u. 5. H-3700 Kazincbarcika Borsod-Abauj-Zemplen Hungary Hungary Active Phenyl chloroformate 217-547-8 1885-14-9 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active Anthranilonitrile 217-549-9 1885-29-6 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Anthranilonitrile 217-549-9 1885-29-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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