Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
(R)-2-(4-hydroxyphenoxy)propanoic acid
D-HPPA; HPOPS
407-960-3 94050-90-5 No longer Valid Intermediate Individual No longer valid 28-09-2010 View substance registered dossier
(R)-2-(4-hydroxyphenoxy)propanoic acid
D-HPPA; HPOPS
407-960-3 94050-90-5 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid
440-090-2 86123-10-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol
929-946-0 - Active Intermediate Joint Intermediate use only 05-12-2017 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate
929-947-6 - Active Intermediate Joint Intermediate use only 31-10-2017 View substance registered dossier
(R)-2-acetamido-3-naphthyl-2-yl-propionic acid
(R)-2-ACETAMIDO-3-NAPHTHYLEN-2-YL-PROPIONIC ACID
440-450-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-amino-3-phenylpropanol
226-086-1 5267-64-1 Active Intermediate Joint Intermediate use only 29-11-2018 View substance registered dossier
(R)-2-aminobutan-1-ol
227-476-4 5856-63-3 Active Intermediate Joint Intermediate use only 19-07-2019 View substance registered dossier
(R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate
942-402-7 - Active Intermediate Joint Intermediate use only 24-09-2021 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(4-CHLOROPHENYL)-PROPIONIC ACID
438-070-3 57292-44-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(PYRIDIN-3-YL) PROPIONIC ACID
441-200-1 98266-33-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 Active Full Joint ≥ 10 to < 100 tonnes 16-12-2020 View substance registered dossier
(R)-3,7-dimethyloct-6-en-1-ol
214-250-5 1117-61-9 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
(R)-3,7-dimethyloct-6-enal
219-194-5 2385-77-5 Active Intermediate Joint Intermediate use only 13-02-2019 View substance registered dossier
(R)-3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate
843-372-7 856408-80-5 Active Intermediate Joint Intermediate use only 23-09-2019 View substance registered dossier
(R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole
921-685-0 - Active Intermediate Joint Intermediate use only 05-04-2018 View substance registered dossier
(R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid
691-120-8 486460-00-8 Active Intermediate Joint Intermediate use only 31-05-2022 View substance registered dossier
(R)-3-[(1-methylpyrrolidin-2-yl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole
430-560-5 180637-89-2 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Active Intermediate Joint Intermediate use only 25-04-2018 View substance registered dossier
(R)-3-chloropropane-1,2-diol
435-560-9 57090-45-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(R)-3-cyclohexyl-2-hydroxypropionic acid
812-501-9 156469-00-0 Active Intermediate Joint Intermediate use only 01-06-2018 View substance registered dossier
(R)-3-phenyllactic acid
230-803-3 7326-19-4 Active Intermediate Joint Intermediate use only 17-05-2018 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate
949-784-4 - Active Intermediate Individual Intermediate use only 25-03-2019 View substance registered dossier
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-760-2 219861-18-4 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile
430-760-2 219861-18-4 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
NuFarm Limited Wyke Lane BD12 9EJ Wyke West Yorkshire United Kingdom United Kingdom No longer Valid (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 2021 View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (R)-2-(4-hydroxyphenoxy)propanoic acid 407-960-3 94050-90-5 - View substance registered dossier
- - - - (R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionic acid 440-090-2 86123-10-6 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol 929-946-0 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate 929-947-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-acetamido-3-naphthyl-2-yl-propionic acid 440-450-9 - - View substance registered dossier
PMC ISOCHEM 32 rue Lavoisier 91710 VERT LE PETIT France France Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-amino-3-phenylpropanol 226-086-1 5267-64-1 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active (R)-2-aminobutan-1-ol 227-476-4 5856-63-3 2019 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - 2018; 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid 438-070-3 57292-44-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid 441-200-1 98266-33-2 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 - View substance registered dossier
International Flavors & Fragrances, I.F.F. (France) S.A.S Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (R)-3,7-dimethyl-1,6-octadien-3-ol 204-811-2 126-91-0 2018 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (R)-3,7-dimethyloct-6-en-1-ol 214-250-5 1117-61-9 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (R)-3,7-dimethyloct-6-enal 219-194-5 2385-77-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (R)-3,7-dimethyloct-6-enal 219-194-5 2385-77-5 2013; 2018; 2019 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (R)-3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate 843-372-7 856408-80-5 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid 691-120-8 486460-00-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-3-[(1-methylpyrrolidin-2-yl)methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indole 430-560-5 180637-89-2 - View substance registered dossier
Covance Clinical Development SA 169 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2018 View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 171 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Cease Manufacture (R)-3-chloropropane-1,2-diol 435-560-9 57090-45-6 2012 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-cyclohexyl-2-hydroxypropionic acid 812-501-9 156469-00-0 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (R)-3-phenyllactic acid 230-803-3 7326-19-4 - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate 949-784-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 2019 View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 430-760-2 219861-18-4 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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