Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters
290-754-9 90218-76-1 Active Full Joint ≥ 10 000 to < 100 000 tonnes 10-06-2021 View substance registered dossier
1,2,4-Benzenetricarboxylic acid, mixed lauryl and octyl triesters
700-342-7 1163775-81-2 Active Full Individual ≥ 100 to < 1 000 tonnes 23-06-2015 View substance registered dossier
1,2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters
304-780-6 94279-36-4 Active Full Joint ≥ 1 000 to < 10 000 tonnes 24-10-2016 View substance registered dossier
1,2,4-Oxadiazol-5(2H)-one, 3-(4-aminophenyl)-
917-912-8 864680-71-7 Active Intermediate Joint Intermediate use only 13-06-2016 View substance registered dossier
1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)-
810-533-8 330459-31-9 Active Full Joint ≥ 0 to < 10 tonnes 07-12-2015 View substance registered dossier
1,2,4-Pyrrolidinetricarboxylic acid, 1-(1,1-dimethylethyl) 2,4-dimethyl ester, (2S,4S)-
807-497-0 1378388-30-7 Active Intermediate Individual Intermediate use only 14-04-2016 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)-
616-178-3 75028-24-9 No longer Valid Intermediate Individual No longer valid 24-06-2013 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)-
616-178-3 75028-24-9 Active Intermediate Joint Intermediate use only 26-06-2020 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(methoxyimino)-, (.alpha.Z)-
456-150-6 72217-12-0 Cease Manufacture NONS Individual Cease manufacture 04-03-2011 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)-
616-285-5 76028-96-1 Active Intermediate Individual Intermediate use only 26-04-2013 View substance registered dossier
1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)-
616-285-5 76028-96-1 Active Intermediate Joint Intermediate use only 09-06-2022 View substance registered dossier
1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-(methoxyimino)-, S-2-benzothiazolyl ester, (.alpha.Z)-
453-580-6 89604-91-1 Active Intermediate Joint Intermediate use only 17-12-2010 View substance registered dossier
1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (.alpha.Z)-
447-420-4 209467-59-4 Cease Manufacture NONS Individual Cease manufacture 22-02-2013 View substance registered dossier
1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (.alpha.Z)-
447-420-4 209467-59-4 Active NONS Joint Tonnage data confidential 09-06-2016 View substance registered dossier
1,2,4-Triazin-3-amine, 6-bromo-
811-180-2 69249-22-5 Active Intermediate Individual Intermediate use only 10-07-2017 View substance registered dossier
1,2,4-triazole
206-022-9 288-88-0 Active Full Joint ≥ 0 to < 10 tonnes 26-04-2022 View substance registered dossier
1,2,4-triazole-3-thiol
221-656-6 3179-31-5 Active Full Joint ≥ 0 to < 10 tonnes 07-09-2020 View substance registered dossier
1,2,4-Triazolidine-3-thione, 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-
606-964-4 222408-90-4 Active Intermediate Individual Intermediate use only 26-11-2010 View substance registered dossier
1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1)
616-309-4 762240-92-6 Active Intermediate Individual Intermediate use only 18-10-2012 View substance registered dossier
1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1)
616-309-4 762240-92-6 Active Intermediate Joint Intermediate use only 31-05-2022 View substance registered dossier
1,2,4-triazolo[4,3-a]pyridin-3(2H)-one
230-191-8 6969-71-7 Active Intermediate Joint Intermediate use only 28-05-2018 View substance registered dossier
1,2,4-Triazolo[4,3-c]pyrimidine-3(2H)-thione, 5-ethoxy-7-fluoro-
695-186-9 166524-68-1 No longer Valid Intermediate Joint No longer valid 22-04-2014 View substance registered dossier
1,2,4-trichlorobenzene 204-428-0 120-82-1 Active Intermediate Joint Intermediate use only 08-05-2018 View substance registered dossier
1,2,4-trimethylbenzene
202-436-9 95-63-6 Active Full Joint ≥ 10 000 to < 100 000 tonnes 21-01-2020 View substance registered dossier
1,2,4-trimethylbenzene-5-sulfonic acid dihydrate
1,2,4-TRIMETHYLBENZENE-5-SULFONIC ACID
420-770-5 3453-84-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Emery Oleochemicals GmbH Paul-Thomas-Straße 56 D-40599 Duesseldorf Germany Germany Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2017 View substance registered dossier
Knoell NL_OR_068 Agro Business Park 75 6708 PV Wageningen Netherlands Netherlands No longer Valid 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2019 View substance registered dossier
POLYNT S.p.A. via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy Italy Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2014; 2021 View substance registered dossier
VALTRIS ENTERPRISES FRANCE ZI Baleycourt 55103 VERDUN FRANCE France France Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2015 View substance registered dossier
TÜV SÜD Iberia S.A.U. (022) Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain Spain Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 - View substance registered dossier
Condensia Quimica SA C/ Junqueras, 16-11-A 08003 Barcelona Spain Spain Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2014 View substance registered dossier
CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Corporation Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland Ireland Cease Manufacture 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2021 View substance registered dossier
Kao Chemicals Europe, S.L. (8) Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2014; 2021 View substance registered dossier
Teknor Apex BV OR-1 Mijnweg 1 (P.O.Box 601, 6160 AP) 6167AC Geleen Please select Netherlands Netherlands Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 - View substance registered dossier
Henkel Global Supply Chain B.V. Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands Netherlands Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 - View substance registered dossier
Kao Chemicals Europe, S.L. (10) Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2021 View substance registered dossier
Ineos Solvents Germany GmbH Roemerstr. 733 47443 Moers Germany Germany Active 1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters 290-754-9 90218-76-1 2013; 2014; 2015; 2016; 2018; 2020 View substance registered dossier
Ineos Solvents Germany GmbH Roemerstr. 733 47443 Moers Germany Germany Active 1,2,4-Benzenetricarboxylic acid, mixed lauryl and octyl triesters 700-342-7 1163775-81-2 2010; 2011; 2015 View substance registered dossier
[Confidential] - - - 1,2,4-Benzenetricarboxylic acid, tri-C9-11-alkyl esters 304-780-6 94279-36-4 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active 1,2,4-Oxadiazol-5(2H)-one, 3-(4-aminophenyl)- 917-912-8 864680-71-7 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Active 1,2,4-Oxadiazol-5(2H)-one, 3-(4-aminophenyl)- 917-912-8 864680-71-7 - View substance registered dossier
[Confidential] - - - 1,2,4-Oxadiazole, 3-phenyl-5-(2-thienyl)- 810-533-8 330459-31-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1,2,4-Pyrrolidinetricarboxylic acid, 1-(1,1-dimethylethyl) 2,4-dimethyl ester, (2S,4S)- 807-497-0 1378388-30-7 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)- 616-178-3 75028-24-9 2021 View substance registered dossier
CHEMSAFE srl on behalf of AZO INTERNATIONAL CHEMICAL ltd Via Ribes, 5 10010 Colleretto Giacosa TO Italy Italy Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(ethoxyimino)-, (.alpha.Z)- 616-178-3 75028-24-9 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-(methoxyimino)-, (.alpha.Z)- 456-150-6 72217-12-0 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)- 616-285-5 76028-96-1 - View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)- 616-285-5 76028-96-1 - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Active 1,2,4-Thiadiazole-3-acetic acid, 5-amino-.alpha.-[[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]imino]-, (.alpha.Z)- 616-285-5 76028-96-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-(methoxyimino)-, S-2-benzothiazolyl ester, (.alpha.Z)- 453-580-6 89604-91-1 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture 1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-(methoxyimino)-, S-2-benzothiazolyl ester, (.alpha.Z)- 453-580-6 89604-91-1 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture 1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (.alpha.Z)- 447-420-4 209467-59-4 2019 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1,2,4-Thiadiazole-3-ethanethioic acid, 5-amino-.alpha.-[(triphenylmethoxy)imino]-, S-2-benzothiazolyl ester, (.alpha.Z)- 447-420-4 209467-59-4 2013; 2016 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 1,2,4-Triazin-3-amine, 6-bromo- 811-180-2 69249-22-5 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1,2,4-triazole 206-022-9 288-88-0 2017; 2020; 2021 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 1,2,4-triazole 206-022-9 288-88-0 - View substance registered dossier
Innospec Deutschland GmbH Thiesstrasse 61 44649 Herne Germany Germany Active 1,2,4-triazole 206-022-9 288-88-0 - View substance registered dossier
[Confidential] - - - 1,2,4-triazole 206-022-9 288-88-0 - View substance registered dossier
SKW Stickstoffwerke Piesteritz GmbH Möllensdorfer Straße 13 06886 Lutherstadt Wittenberg Germany Germany Cease Manufacture 1,2,4-triazole 206-022-9 288-88-0 2019 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active 1,2,4-triazole 206-022-9 288-88-0 2010; 2013; 2014; 2015; 2018; 2019; 2020; 2022 View substance registered dossier
ESIM Chemicals GmbH St.-Peter-Strasse 25 4020 Linz Austria Austria No longer Valid 1,2,4-triazole 206-022-9 288-88-0 2017 View substance registered dossier
[Confidential] - - - 1,2,4-triazole-3-thiol 221-656-6 3179-31-5 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 1,2,4-Triazolidine-3-thione, 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]- 606-964-4 222408-90-4 2010 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1) 616-309-4 762240-92-6 - View substance registered dossier
Flavine Europe GmbH Wehrlestrasse 12 81679 Munich Germany Germany Active 1,2,4-triazolo[4,3-a]pyridin-3(2H)-one 230-191-8 6969-71-7 - View substance registered dossier
Chemsafe Via Ribes 5 10010 Colleretto Giacosa (TO) Italy Italy Active 1,2,4-triazolo[4,3-a]pyridin-3(2H)-one 230-191-8 6969-71-7 - View substance registered dossier
Chemosyntha BV Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium Belgium Active 1,2,4-triazolo[4,3-a]pyridin-3(2H)-one 230-191-8 6969-71-7 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 1,2,4-triazolo[4,3-a]pyridin-3(2H)-one 230-191-8 6969-71-7 - View substance registered dossier
A.C.R.A.F. Spa Via Amelia 70 00181 Roma Italy Italy Active 1,2,4-triazolo[4,3-a]pyridin-3(2H)-one 230-191-8 6969-71-7 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active 1,2,4-triazolo[4,3-a]pyridin-3(2H)-one 230-191-8 6969-71-7 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 1,2,4-Triazolo[4,3-c]pyrimidine-3(2H)-thione, 5-ethoxy-7-fluoro- 695-186-9 166524-68-1 2021 View substance registered dossier
Lanxess Deutschland GmbH Kennedyplatz 1 50569 Köln Germany Germany Active 1,2,4-trichlorobenzene 204-428-0 120-82-1 - View substance registered dossier
Merck Schuchardt OHG Eduard-Buchner-Str. 85662 Hohenbrunn Germany Germany Active 1,2,4-trichlorobenzene 204-428-0 120-82-1 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 1,2,4-trichlorobenzene 204-428-0 120-82-1 - View substance registered dossier
PerkinElmer Health Sciences B.V. Rigaweg 22 9723 TH Groningen Groningen Netherlands Netherlands Active 1,2,4-trimethylbenzene 202-436-9 95-63-6 2019 View substance registered dossier
DHC Solvent Chemie GmbH Timmerhellstraße 28 45478 Mülheim an der Ruhr Germany Germany Active 1,2,4-trimethylbenzene 202-436-9 95-63-6 2018; 2020 View substance registered dossier
POLYNT S.p.A. via Enrico Fermi, 51 I-24020 Scanzorosciate BG Italy Italy Active 1,2,4-trimethylbenzene 202-436-9 95-63-6 - View substance registered dossier
SARLUX srl S.S. Sulcitana 195 km. 19 09018 Sarroch (CA) Sardinia Italy Italy Active 1,2,4-trimethylbenzene 202-436-9 95-63-6 2012; 2013; 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 1,2,4-trimethylbenzene-5-sulfonic acid dihydrate 420-770-5 3453-84-7 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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