Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Cease Manufacture Intermediate Individual Cease manufacture 19-05-2009 View substance registered dossier
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Active Intermediate Individual Intermediate use only 02-08-2011 View substance registered dossier
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Active Intermediate Individual Intermediate use only 31-08-2011 View substance registered dossier
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Active Intermediate Individual Intermediate use only 02-02-2011 View substance registered dossier
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
ROP-3M
412-400-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2,4-difluoro-α-(1H-1,2,4-triazol-1-yl)acetophenone hydrochloride
UK-51,060-01
412-390-3 86386-75-6 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2,2-dibromo-2-nitroethanol
PERMACHEM N21
412-380-9 69094-18-4 No longer Valid NONS Individual No longer valid 19-02-2009 View substance registered dossier
STAGE 5
412-370-4 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2-methyl-1,3-propanediol
MP DIOL(R) GLYCOL
412-350-5 2163-42-0 Active Full Joint ≥ 1 000 tonnes 01-03-2022 View substance registered dossier
2-methyl-1,3-propanediol
MP DIOL(R) GLYCOL
412-350-5 2163-42-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
N-acetyl-N-[5-cyano-3-(2-dibutylamino-4-phenylthiazol-5-yl-methylene)-4-methyl-2,6-dioxo-1,2,3,6-tetrahydropyridin-1-yl]benzamide
SE-499
412-340-0 147741-93-3 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
ROP-32M
412-330-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Sodium 2-anilino-5-(2-nitro-4-(N-phenylsulfamoyl))anilinobenzenesulfonate
NSGBB; YELLOW BROWN E-GLN
412-320-1 31361-99-6 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
2-(O-aminooxy)ethylamine dihydrochloride
AMINOETHER
412-310-7 37866-45-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol
AMBER CORE
412-300-2 139504-68-0 Active Full Joint ≥ 100 to < 1 000 tonnes 28-12-2021 View substance registered dossier
1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol
AMBER CORE
412-300-2 139504-68-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl 2-cyclohexylpropionate
POIRENATE
412-280-5 2511-00-4 Active Full Joint Tonnage data confidential 17-04-2013 View substance registered dossier
2-cyclohexylpropanal
POLLENAL II
412-270-0 2109-22-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
A mixture of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diylprop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecan-1,16-diylprop-2-enoate
MONO 442
412-260-6 52658-19-2 Active Full Joint ≥ 100 to < 1 000 tonnes 24-05-2019 View substance registered dossier
A mixture of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diylprop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecan-1,16-diylprop-2-enoate
MONO 442
412-260-6 52658-19-2 Active NONS Joint Tonnage data confidential 23-10-2012 View substance registered dossier
2-acetylamino-6-chloro-4-[(4-diethylamino)-2-methylphenyl-imino]-5-methyl-1-oxo-2,5-cyclohexadiene
TSD-44
412-250-1 102387-48-4 Active NONS Joint Tonnage data confidential 29-10-2012 View substance registered dossier
Hexasodium 1,1'-[(1-amino-8-hydroxy-3,6-disulfonate-2,7-naphthalenediyl)bis(azo(4-sulfonate-1,3-phenyl)imino[6-[(4-chloro-3-sulfonatophenyl)amino]-1,3,5-triazin-2,4-diyl]]]bis[3-carboxypyridinium] dihydroxide
C.I. REACTIVE BLUE 217
412-240-7 89797-03-5 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
3-aminobenzylamine
SUBSTANCE S68494
412-230-2 4403-70-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
A polymer of: α-hydro-ω-hydroxy-poly(oxy(methyl-1,2-ethanediyl)), oxirane, propane-1,2,3-triol, 1,3-diisocyanomethylbenzene, 3-mercaptopropan-1-ol and ethyltrimethylsilane
PERMAPOL MS-200
412-220-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Laboratoires Merck Sharp & Dohme - Chibret SNC Usine de La Vallée Zone Industrielle de Blavozy 43700 Saint-Germain Laprade Europe France France Cease Manufacture 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 2011 View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 2011 View substance registered dossier
Only representative (No publishable name) - - Active 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 2011 View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 2008; 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active ROP-3M 412-400-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2,4-difluoro-α-(1H-1,2,4-triazol-1-yl)acetophenone hydrochloride 412-390-3 86386-75-6 - View substance registered dossier
SUEZ WATER TECHNOLOGIES & SOLUTIONS (UK) LIMITED PARTNERSHIP HydroHouse - Newcombe Way Orton Southgate PE2 6SE Peterborough Cambridgeshire United Kingdom United Kingdom No longer Valid 2,2-dibromo-2-nitroethanol 412-380-9 69094-18-4 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active STAGE 5 412-370-4 - - View substance registered dossier
HP Production Company Limited Barnhall Road Liffey Park Technology Campus . Leixlip Co.Kildare Ireland Ireland Cease Manufacture 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2019 View substance registered dossier
CCD (Germany) GmbH Berliner Allee 55 40212 Düsseldorf Germany Germany Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2022 View substance registered dossier
LyondellBasell Industries Holdings BV_OR1_Lyondell Chemical Company Delftseplein 27E 3013 AA Rottterdam Zuid Holland Netherlands Netherlands Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2013 View substance registered dossier
HP Europe B.V. Mail Box: CV11300 Omega house, Stone Business Park ST15 0SR Stone Netherlands Netherlands Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2013; 2019 View substance registered dossier
WSP Deutschland A.G. (OR8) Dingolfinger Straße 1-15 81673 München Germany Germany Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2019; 2021 View substance registered dossier
HP Deutschland GmbH Herrenberger Strasse 140 71034 Boeblingen Germany Germany Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2013; 2019 View substance registered dossier
Gantrade Europe BVBA Blokhuisstraat 47 J 2800 Mechelen Belgium Belgium Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 - View substance registered dossier
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany Germany Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 - View substance registered dossier
Lyondell Chemie Nederland B.V. Deltseplein 27E 3013 AA Rotterdam Netherlands Netherlands Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2010; 2012; 2013; 2014; 2016; 2017; 2019 View substance registered dossier
[Confidential] - - - 2-methyl-1,3-propanediol 412-350-5 2163-42-0 - View substance registered dossier
ADEKA Europe GmbH Berliner Allee 22 40212 Düsseldorf Germany Germany Cease Manufacture 2-methyl-1,3-propanediol 412-350-5 2163-42-0 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-methyl-1,3-propanediol 412-350-5 2163-42-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active N-acetyl-N-[5-cyano-3-(2-dibutylamino-4-phenylthiazol-5-yl-methylene)-4-methyl-2,6-dioxo-1,2,3,6-tetrahydropyridin-1-yl]benzamide 412-340-0 147741-93-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active ROP-32M 412-330-6 - - View substance registered dossier
Archroma UK, Ltd 1 Bartholomew Lane EC2N 2AX London United Kingdom United Kingdom No longer Valid Sodium 2-anilino-5-(2-nitro-4-(N-phenylsulfamoyl))anilinobenzenesulfonate 412-320-1 31361-99-6 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority. - - Active Sodium 2-anilino-5-(2-nitro-4-(N-phenylsulfamoyl))anilinobenzenesulfonate 412-320-1 31361-99-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-(O-aminooxy)ethylamine dihydrochloride 412-310-7 37866-45-8 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 2020 View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 2021 View substance registered dossier
Intertek Deutschland GmbH IEFC* Stangenstr.1 70771 Leinfelden-Echterdingen Germany Germany Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 - View substance registered dossier
Kao Chemicals Europe, S.L. (2) Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 2010; 2011; 2012; 2013; 2020; 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active 1-[(2-tert-butylcyclohexyl)oxy]butan-2-ol 412-300-2 139504-68-0 - View substance registered dossier
Kao Chemicals Europe, S.L. (2) Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active Ethyl 2-cyclohexylpropionate 412-280-5 2511-00-4 - View substance registered dossier
Kao Corporation, S.A. Puig dels Tudons, 10 08210 Barbera del Valles Barcelona Spain Spain Active 2-cyclohexylpropanal 412-270-0 2109-22-0 - View substance registered dossier
Allnex Belgium NV/SA Anderlechtstraat 33 1620 Drogenbos Belgium Belgium Active A mixture of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diylprop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecan-1,16-diylprop-2-enoate 412-260-6 52658-19-2 2009; 2011; 2019 View substance registered dossier
RAHN GmbH Hahnstrasse 70 60528 Frankfurt/Main Germany Germany Active A mixture of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diylprop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecan-1,16-diylprop-2-enoate 412-260-6 52658-19-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active A mixture of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diylprop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecan-1,16-diylprop-2-enoate 412-260-6 52658-19-2 - View substance registered dossier
Merck Performance Materials GmbH Rheingaustrasse 190-196 65203 Wiesbaden Germany Germany Cease Manufacture A mixture of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diylprop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecan-1,16-diylprop-2-enoate 412-260-6 52658-19-2 2018 View substance registered dossier
Specialty Electronic Materials Netherlands BV Baanhoekweg 22 3313 LA Dordrecht Netherlands Netherlands Cease Manufacture A mixture of: 7,9,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecane-1,16-diylprop-2-enoate; 7,7,9-trimethyl-3,14-dioxa-4,13-dioxo-5,12-diazahexadecan-1,16-diylprop-2-enoate 412-260-6 52658-19-2 2020 View substance registered dossier
ExponentOR37I Block 1, Blanchardstown Corporate Park Ballycoolen Road, Blanchardstown D15 AKK1 Dublin Ireland Ireland Active 2-acetylamino-6-chloro-4-[(4-diethylamino)-2-methylphenyl-imino]-5-methyl-1-oxo-2,5-cyclohexadiene 412-250-1 102387-48-4 2011; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-acetylamino-6-chloro-4-[(4-diethylamino)-2-methylphenyl-imino]-5-methyl-1-oxo-2,5-cyclohexadiene 412-250-1 102387-48-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active Hexasodium 1,1'-[(1-amino-8-hydroxy-3,6-disulfonate-2,7-naphthalenediyl)bis(azo(4-sulfonate-1,3-phenyl)imino[6-[(4-chloro-3-sulfonatophenyl)amino]-1,3,5-triazin-2,4-diyl]]]bis[3-carboxypyridinium] dihydroxide 412-240-7 89797-03-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active Hexasodium 1,1'-[(1-amino-8-hydroxy-3,6-disulfonate-2,7-naphthalenediyl)bis(azo(4-sulfonate-1,3-phenyl)imino[6-[(4-chloro-3-sulfonatophenyl)amino]-1,3,5-triazin-2,4-diyl]]]bis[3-carboxypyridinium] dihydroxide 412-240-7 89797-03-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active Hexasodium 1,1'-[(1-amino-8-hydroxy-3,6-disulfonate-2,7-naphthalenediyl)bis(azo(4-sulfonate-1,3-phenyl)imino[6-[(4-chloro-3-sulfonatophenyl)amino]-1,3,5-triazin-2,4-diyl]]]bis[3-carboxypyridinium] dihydroxide 412-240-7 89797-03-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active Hexasodium 1,1'-[(1-amino-8-hydroxy-3,6-disulfonate-2,7-naphthalenediyl)bis(azo(4-sulfonate-1,3-phenyl)imino[6-[(4-chloro-3-sulfonatophenyl)amino]-1,3,5-triazin-2,4-diyl]]]bis[3-carboxypyridinium] dihydroxide 412-240-7 89797-03-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Portuguese competent national authority. - - Active Hexasodium 1,1'-[(1-amino-8-hydroxy-3,6-disulfonate-2,7-naphthalenediyl)bis(azo(4-sulfonate-1,3-phenyl)imino[6-[(4-chloro-3-sulfonatophenyl)amino]-1,3,5-triazin-2,4-diyl]]]bis[3-carboxypyridinium] dihydroxide 412-240-7 89797-03-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 3-aminobenzylamine 412-230-2 4403-70-7 - View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Active 3-aminobenzylamine 412-230-2 4403-70-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active A polymer of: α-hydro-ω-hydroxy-poly(oxy(methyl-1,2-ethanediyl)), oxirane, propane-1,2,3-triol, 1,3-diisocyanomethylbenzene, 3-mercaptopropan-1-ol and ethyltrimethylsilane 412-220-8 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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