Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
N-[4-cyano-3-trifluoromethylphenyl]methacrylamide
427-880-2 90357-53-2 Active Intermediate Individual Intermediate use only 14-07-2017 View substance registered dossier
N-[4-cyano-3-trifluoromethylphenyl]methacrylamide
427-880-2 90357-53-2 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
N-[6,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6-oxo-1H-purin-2-yl]acetamide
424-550-1 84245-12-5 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
N-acetyl-β-D-glucosamine
231-368-2 7512-17-6 Active Full Individual ≥ 0 to < 10 tonnes 19-06-2020 View substance registered dossier
N-acetylglutamic acid
214-708-4 1188-37-0 Active Intermediate Individual Intermediate use only 24-03-2015 View substance registered dossier
N-acetylsulphanilyl chloride
204-485-1 121-60-8 Active Intermediate Individual Intermediate use only 14-01-2015 View substance registered dossier
N-acetylsulphanilyl chloride
204-485-1 121-60-8 Active Intermediate Individual Intermediate use only 30-04-2014 View substance registered dossier
N-amidino-N-methylglycine-2-oxopropionate
429-120-5 208535-04-0 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
N-amino-N-carboxymethylglycine
F.H.D.A.
403-510-5 19247-05-3 Active NONS Individual Tonnage data confidential 29-07-2011 View substance registered dossier
N-benzyl-2-bromo-3-methoxypropanamide
700-538-2 705283-58-5 Cease Manufacture Intermediate Individual Cease manufacture 14-06-2011 View substance registered dossier
N-benzyl-N-ethyl-(4-(5-nitro-benzo[c]isothiazol-3-ylazo)phenyl)amine
425-300-2 186450-73-7 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
N-butyl acetate
204-658-1 123-86-4 No longer Valid Full Individual No longer valid 11-01-2016 View substance registered dossier
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine
252-899-6 36177-92-1 Active Intermediate Individual Intermediate use only 05-11-2012 View substance registered dossier
N-butyl-2-(4-morpholinylcarbonyl)benzamide
EP 389
407-730-2 104958-67-0 No longer Valid NONS Individual No longer valid 17-11-2010 View substance registered dossier
N-butylphosphorothioic triamide
435-740-7 94317-64-3 Active Full Individual ≥ 10 to < 100 tonnes 20-12-2012 View substance registered dossier
N-butylphosphorothioic triamide
435-740-7 94317-64-3 Cease Manufacture Intermediate Individual Cease manufacture 20-12-2012 View substance registered dossier
N-butylphosphorothioic triamide
435-740-7 94317-64-3 Cease Manufacture Intermediate Individual Cease manufacture 03-01-2013 View substance registered dossier
n-Butyoxycarbonyl-O-n-butyl thionocarbamate
476-230-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-carboxymethyliminobis(ethylenenitrilo)tetra(acetic acid)
200-652-8 67-43-6 Active Intermediate Individual Intermediate use only 14-01-2013 View substance registered dossier
N-cyclohexyl-S,S-dioxobenzo[b]tiophene-2-carboxamide
PREVENTOL VP OC 3061
423-990-1 149118-66-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-decyl-4-nitrobenzamide
445-880-0 64026-19-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-dodecyl-4-methoxybenzamide
442-340-6 1854-15-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-ethyl-3-trimethoxysilyl-2-methyl-propanamine
437-720-3 227085-51-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-ethyl-N-(3-methylphenyl)propionamide
AGARBOIS
423-640-6 179911-08-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-ethyl-o-toluidine
202-354-3 94-68-8 Active Intermediate Individual Intermediate use only 15-10-2018 View substance registered dossier
N-ethyl-p-methoxy-α-methylphenethylamine
238-339-3 14367-46-5 Active Intermediate Individual Intermediate use only 13-02-2014 View substance registered dossier
N-FAS
456-080-6 - Cease Manufacture Intermediate Individual Cease manufacture 09-12-2011 View substance registered dossier
N-hexadecyl(or octadecyl)-N-hexadecyl(or octadecyl)benzamide
DTBA
401-980-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-isotridecyl-iso-tridecanamide
435-780-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-methyl-1-(methylthio)-2-nitrovinylamine
263-266-9 61832-41-5 Active Intermediate Individual Intermediate use only 09-02-2012 View substance registered dossier
N-methyl-C12-14-(even numbered)-alkyl-1-amine
700-406-4 1335203-22-9 Active Intermediate Individual Intermediate use only 15-03-2010 View substance registered dossier
N-methyl-N-(trimethylsilyl)acetamide
231-217-0 7449-74-3 Active Intermediate Individual Intermediate use only 04-03-2019 View substance registered dossier
N-methylaniline
202-870-9 100-61-8 Active Intermediate Individual Intermediate use only 23-06-2010 View substance registered dossier
N-methyldidecylamine
230-990-1 7396-58-9 Active Full Individual ≥ 1 to < 10 tonnes 03-05-2018 View substance registered dossier
N-methylformamide
204-624-6 123-39-7 Active Intermediate Individual Intermediate use only 29-10-2012 View substance registered dossier
N-methylformamide
204-624-6 123-39-7 Active Intermediate Individual Intermediate use only 11-11-2014 View substance registered dossier
N-methylhyoscinium bromide
205-844-5 155-41-9 Cease Manufacture Intermediate Individual Cease manufacture 04-03-2013 View substance registered dossier
N-octylpyridin-4-amine
265-019-0 64690-19-3 Active Intermediate Individual Intermediate use only 22-01-2020 View substance registered dossier
N-pentan-2-ylidenehydroxylamine 484-470-6 623-40-5 Active NONS Individual Tonnage data confidential 24-06-2009 View substance registered dossier
N-tert-butyl-3-methylpicolinamide
LORATADINE INTERMEDIATE; LRD-A
406-720-5 32998-95-1 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
RH-5992
412-850-3 112410-23-8 Cease Manufacture NONS Individual Cease manufacture 15-12-2008 View substance registered dossier
N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide
813-231-4 1195768-23-0 Active Intermediate Individual Intermediate use only 25-04-2018 View substance registered dossier
N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine
- - Active Full Individual ≥ 0 to < 10 tonnes 05-04-2022 View substance registered dossier
N-{[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}-L-PHENYLALANYL-L-VALYL-N-(TRIPHENYLMETHYL)-L-GLUTAMINYL-1-(TERT-BUTOXYCARBONYL)-L-TRYPTOPHYL-L-LEUCYL-L-ISOLEUCYL-L-ALANYLGLYCINE
874-918-2 2461524-68-3 Active Intermediate Individual Intermediate use only 22-11-2021 View substance registered dossier
N-{[4-(2,2-DICYANO-1-HYDROXYETHENYL)PHENYL]METHYL}-5-FLUORO-2-METHOXYBENZAMIDE
953-101-5 - Active Intermediate Individual Intermediate use only 21-12-2020 View substance registered dossier
N-{[Benzyl(ethyl)amino]-[(chloro-cyano-nitrophenyl)substituted]phenyl}acetamide
- - Active Full Individual ≥ 1 to < 10 tonnes 15-05-2020 View substance registered dossier
N4,N4'-bis(4-methoxy-2-methylphenyl)-N4,N4'-diphenyl[1,1'-biphenyl]-4,4'-diamine
438-140-3 169685-34-1 No longer Valid NONS Individual No longer valid 29-10-2012 View substance registered dossier
N4-[3-(1H-imidazol-1-yl)propyl]-2-methylbenzene-1,4-diamine trihydrochloride
700-345-3 515851-08-8 Cease Manufacture NA Individual Cease manufacture 09-02-2010 View substance registered dossier
N6-(1-oxooctyl)-L-lysine
245-854-7 23735-96-8 Active Full Individual ≥ 1 to < 10 tonnes 11-03-2015 View substance registered dossier
NAD
405-970-2 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Tocelo Pharma BV Zuidwal 4 5211JK 's-Hertogenbosch Noord-Brabant Netherlands Netherlands Active N-[4-cyano-3-trifluoromethylphenyl]methacrylamide 427-880-2 90357-53-2 - View substance registered dossier
AstraZeneca Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom United Kingdom No longer Valid N-[4-cyano-3-trifluoromethylphenyl]methacrylamide 427-880-2 90357-53-2 2021 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture N-[6,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6-oxo-1H-purin-2-yl]acetamide 424-550-1 84245-12-5 2020 View substance registered dossier
RN Laboratories Europe B.V. Joop Geesinkweg 701 1114 AB Amsterdam Netherlands Netherlands Active N-acetyl-β-D-glucosamine 231-368-2 7512-17-6 2020 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active N-acetylglutamic acid 214-708-4 1188-37-0 - View substance registered dossier
Sun Chemical Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active N-acetylsulphanilyl chloride 204-485-1 121-60-8 - View substance registered dossier
[Confidential] - - - N-acetylsulphanilyl chloride 204-485-1 121-60-8 - View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Cease Manufacture N-amidino-N-methylglycine-2-oxopropionate 429-120-5 208535-04-0 2020 View substance registered dossier
FUJIFILM Belgium NV Europark Noord 21-22 9100 Sint-Niklaas Belgium Belgium Active N-amino-N-carboxymethylglycine 403-510-5 19247-05-3 2011 View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Cease Manufacture N-benzyl-2-bromo-3-methoxypropanamide 700-538-2 705283-58-5 2020 View substance registered dossier
DyStar Colours Distribution GmbH Am Prime-Parc 12 65479 Raunheim Germany Germany Cease Manufacture N-benzyl-N-ethyl-(4-(5-nitro-benzo[c]isothiazol-3-ylazo)phenyl)amine 425-300-2 186450-73-7 2012 View substance registered dossier
Bestseller A/S Moltrup Landevej 201 6100 Haderslev Denmark Denmark No longer Valid N-butyl acetate 204-658-1 123-86-4 2017 View substance registered dossier
3V Sigma S.p.A Torquato Tasso 58 24121 Bergamo Italy Italy Active N-butyl-2,2,6,6-tetramethylpiperidin-4-amine 252-899-6 36177-92-1 - View substance registered dossier
Huntsman Advanced Materials (UK) Ltd Concordia House Glenarm Road Wynyard Business Park TS22 5FB Billingham United Kingdom United Kingdom No longer Valid N-butyl-2-(4-morpholinylcarbonyl)benzamide 407-730-2 104958-67-0 2021 View substance registered dossier
EuroChem Agro GmbH Reichskanzler-Müller-Staße 23 68165 Mannheim Baden-Württemberg Germany Germany Active N-butylphosphorothioic triamide 435-740-7 94317-64-3 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture N-butylphosphorothioic triamide 435-740-7 94317-64-3 2015 View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture N-butylphosphorothioic triamide 435-740-7 94317-64-3 2014 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active n-Butyoxycarbonyl-O-n-butyl thionocarbamate 476-230-4 - - View substance registered dossier
Przedsiębiorstwo Produkcyjno- Consultingowe ADOB Sp. z o.o. Sp. jawna Kołodzieja 11 61-070 Poznań Poland Poland Poland Active N-carboxymethyliminobis(ethylenenitrilo)tetra(acetic acid) 200-652-8 67-43-6 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active N-cyclohexyl-S,S-dioxobenzo[b]tiophene-2-carboxamide 423-990-1 149118-66-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active N-decyl-4-nitrobenzamide 445-880-0 64026-19-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active N-dodecyl-4-methoxybenzamide 442-340-6 1854-15-5 - View substance registered dossier
Momentive Performance Materials GmbH Chempark Building V7 51368 Leverkusen NRW Germany Germany Active N-ethyl-3-trimethoxysilyl-2-methyl-propanamine 437-720-3 227085-51-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active N-ethyl-N-(3-methylphenyl)propionamide 423-640-6 179911-08-1 - View substance registered dossier
MEDIKIMIKA Srl via J.M.Escrivà de Balaguer 6 21047 SARONNO ITALY Italy Italy Active N-ethyl-o-toluidine 202-354-3 94-68-8 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active N-ethyl-p-methoxy-α-methylphenethylamine 238-339-3 14367-46-5 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture N-FAS 456-080-6 - 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active N-hexadecyl(or octadecyl)-N-hexadecyl(or octadecyl)benzamide 401-980-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active N-isotridecyl-iso-tridecanamide 435-780-5 - - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active N-methyl-1-(methylthio)-2-nitrovinylamine 263-266-9 61832-41-5 - View substance registered dossier
Nouryon Surface Chemistry AB Stenunge Allé 3 - S-44485 Stenungsund - Sweden Sweden Active N-methyl-C12-14-(even numbered)-alkyl-1-amine 700-406-4 1335203-22-9 - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active N-methyl-N-(trimethylsilyl)acetamide 231-217-0 7449-74-3 - View substance registered dossier
Only representative (No publishable name) - - Active N-methylaniline 202-870-9 100-61-8 - View substance registered dossier
3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium Belgium Active N-methyldidecylamine 230-990-1 7396-58-9 - View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active N-methylformamide 204-624-6 123-39-7 2012 View substance registered dossier
Chemische Fabrik Berg GmbH Mainthalstrasse 3 06749 Bitterfeld-Wolfen Germany Germany Active N-methylformamide 204-624-6 123-39-7 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture N-methylhyoscinium bromide 205-844-5 155-41-9 2019 View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Active N-octylpyridin-4-amine 265-019-0 64690-19-3 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active N-pentan-2-ylidenehydroxylamine 484-470-6 623-40-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active N-tert-butyl-3-methylpicolinamide 406-720-5 32998-95-1 - View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Cease Manufacture N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide 412-850-3 112410-23-8 2016 View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Active N-{3-[5-(2-chloro-4-pyrimidinyl)-2-(1,1-diethylethyl)-1,3-thiazol-4-yl]-2-fluoraphenyl}-2,6-difluorobenzenesulfonamide 813-231-4 1195768-23-0 - View substance registered dossier
Nouryon Surface Chemistry AB Stenunge Allé 3 - S-44485 Stenungsund - Sweden Sweden Active N-{3-[C12-14-(even numbered)-alkyloxy]propyl}propane-1,3-diamine - - - View substance registered dossier
[Confidential] - - - N-{[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}-L-PHENYLALANYL-L-VALYL-N-(TRIPHENYLMETHYL)-L-GLUTAMINYL-1-(TERT-BUTOXYCARBONYL)-L-TRYPTOPHYL-L-LEUCYL-L-ISOLEUCYL-L-ALANYLGLYCINE 874-918-2 2461524-68-3 - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active N-{[4-(2,2-DICYANO-1-HYDROXYETHENYL)PHENYL]METHYL}-5-FLUORO-2-METHOXYBENZAMIDE 953-101-5 - 2020 View substance registered dossier
Huntsman Textile Effects (Germany) GmbH Rehlinger Str. 1 D-86462 Langweid a.Lech Germany Germany Active N-{[Benzyl(ethyl)amino]-[(chloro-cyano-nitrophenyl)substituted]phenyl}acetamide - - - View substance registered dossier
Envigo Research Limited 83 Shardlow Business Park London Road DE72 2GD Shardlow Derbyshire United Kingdom United Kingdom No longer Valid N4,N4'-bis(4-methoxy-2-methylphenyl)-N4,N4'-diphenyl[1,1'-biphenyl]-4,4'-diamine 438-140-3 169685-34-1 2021 View substance registered dossier
Henkel AG & Co.KGaA - Non Phase In Substances Henkelstrasse 67 40589 Duesseldorf Germany Germany Cease Manufacture N4-[3-(1H-imidazol-1-yl)propyl]-2-methylbenzene-1,4-diamine trihydrochloride 700-345-3 515851-08-8 2010 View substance registered dossier
Ajinomoto OmniChem (OR) Cooppallaan 91 9230 Wetteren Belgium Belgium Active N6-(1-oxooctyl)-L-lysine 245-854-7 23735-96-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active NAD 405-970-2 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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