Registered substances

Registered substances

Registered substances

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We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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(2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol
667-304-9 6564-72-3 Active Intermediate Joint Intermediate use only 31-12-2020 View substance registered dossier
(2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1)
947-432-4 - Active Intermediate Joint Intermediate use only 04-09-2020 View substance registered dossier
(2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2)
954-871-5 - Active Intermediate Individual Intermediate use only 19-08-2021 View substance registered dossier
(2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate
942-044-1 - Active Intermediate Joint Intermediate use only 27-02-2017 View substance registered dossier
(2S,3S,4R)-3-ethyl-4-hydroxy-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate
813-641-3 1799733-43-9 Active Intermediate Joint Intermediate use only 18-04-2018 View substance registered dossier
(2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate
938-481-2 - Active Intermediate Joint Intermediate use only 31-10-2018 View substance registered dossier
(2S,4aR)-1,1,5,5-tetramethyl-1,3,4,5,6,7-hexahydro-2H-2,4a-methanonaphthalen-7-ol
942-036-8 645413-57-6 Active Intermediate Joint Intermediate use only 01-07-2020 View substance registered dossier
(2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one;5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one
423-090-7 156732-13-7 Active Intermediate Joint Intermediate use only 12-06-2018 View substance registered dossier
(2S,5S,32S)-5-{[(5S,8S,11S,14S,17S)-11-[(2R)-BUTAN-2-YL]-8-{4-[(TERT-BUTOXYCARBONYL)AMINO]BUTYL}-5-(2-TERT-BUTOXY-2-OXOETHYL)-1-(9H-FLUOREN-9-YL)-14-METHYL-3,6,9,12,15,18-HEXAOXO-17-{3-OXO-3-[(TRIPHENYLMETHYL)AMINO]PROPYL}-2-OXA-4,7,10,13,16-PENTAAZAOCTADECAN-18-YL]AMINO}-32-(TERT-BUTOXYCARBONYL)-2,55,55-TRIMETHYL-4,11,20,29,34,53-HEXAOXO-13,16,22,25,54-PENTAOXA-3,10,19,28,33-PENTAAZAHEXAPENTACONTAN-1-OIC ACID
954-943-6 - Active Intermediate Individual Intermediate use only 02-09-2021 View substance registered dossier
(2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
255-799-0 42399-49-5 Active Intermediate Joint Intermediate use only 19-10-2018 View substance registered dossier
(2S-cis)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
255-795-9 42399-40-6 Active Intermediate Joint Intermediate use only 09-04-2018 View substance registered dossier
(2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid
279-393-8 80082-65-1 Active Intermediate Joint Intermediate use only 23-02-2018 View substance registered dossier
(2Z)-7-chloro-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid
618-065-4 877674-77-6 Active Intermediate Joint Intermediate use only 13-09-2017 View substance registered dossier
(2α,6α,11R*)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide
248-106-8 26918-40-1 Active Intermediate Joint Intermediate use only 26-04-2018 View substance registered dossier
(3,3-diethoxy-1-propenyl)benzene
230-467-8 7148-78-9 Active Intermediate Individual Intermediate use only 13-11-2013 View substance registered dossier
(3,4-diethoxyphenyl)acetonitrile
248-479-7 27472-21-5 Active Intermediate Joint Intermediate use only 06-01-2022 View substance registered dossier
(3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane)
951-684-0 - Active Intermediate Joint Intermediate use only 26-02-2021 View substance registered dossier
(3-acetyloxy-5-carbonochloridoylphenyl) acetate
855-283-0 39192-49-9 Active Intermediate Joint Intermediate use only 05-06-2020 View substance registered dossier
(3-bromopropyl)benzene
211-294-7 637-59-2 Active Intermediate Joint Intermediate use only 14-05-2018 View substance registered dossier
(3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide
629-007-2 17857-14-6 Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
(3-chloro-2-hydroxypropyl)dimethyloctadecylammonium chloride
221-083-1 3001-63-6 Active Intermediate Individual Intermediate use only 22-07-2021 View substance registered dossier
(3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride
255-578-9 41892-01-7 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
(3-chloro-2-hydroxypropyl)trimethylammonium chloride
222-048-3 3327-22-8 Active Intermediate Individual Intermediate use only 08-01-2014 View substance registered dossier
(3-chloro-2-hydroxypropyl)trimethylammonium chloride
222-048-3 3327-22-8 Active Intermediate Joint Intermediate use only 29-07-2021 View substance registered dossier
(3-chloroprop-1-enyl)benzene
220-246-4 2687-12-9 Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(3-chloropropyl)benzene
203-210-2 104-52-9 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(3-chloropropyl)diethoxymethylsilane
236-828-6 13501-76-3 Active Intermediate Joint Intermediate use only 04-05-2015 View substance registered dossier
(3-chloropropyl)methoxydimethylsilane
242-055-5 18171-14-7 Active Intermediate Joint Intermediate use only 15-02-2018 View substance registered dossier
(3-cyano-2-hydroxypropyl)trimethylammonium chloride
242-684-5 18933-33-0 Active Intermediate Joint Intermediate use only 03-10-2019 View substance registered dossier
(3-methoxyphenyl)acetonitrile
243-428-5 19924-43-7 Active Intermediate Joint Intermediate use only 19-05-2017 View substance registered dossier
(3-methyl-1,4-dioxo-2-naphthyl) 4-nitrobenzoate
604-586-4 14748-93-7 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(3-Methyl-but-2-enyloxy)-benzol
846-080-8 14309-15-0 Active Intermediate Individual Intermediate use only 01-07-2020 View substance registered dossier
(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate
813-124-2 1061337-51-6 Active Intermediate Individual Intermediate use only 25-09-2018 View substance registered dossier
(3aR,4R,6R,6aR)-4-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-4-carbonitrile
857-886-4 1191237-80-5 Active Intermediate Joint Intermediate use only 07-09-2020 View substance registered dossier
(3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
608-721-8 32233-40-2 Active Intermediate Joint Intermediate use only 18-04-2018 View substance registered dossier
(3aα,4α,7α,7aα)-octahydro-4,7-methano-1H-indene
220-586-3 2825-83-4 Active Intermediate Joint Intermediate use only 10-04-2018 View substance registered dossier
(3E)-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pent-3-en-2-one
948-348-0 208034-56-4 Active Intermediate Joint Intermediate use only 10-09-2019 View substance registered dossier
(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-ol
810-303-7 459-89-2 Active Intermediate Joint Intermediate use only 25-09-2018 View substance registered dossier
(3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine
836-285-0 125349-37-3 Active Intermediate Joint Intermediate use only 02-03-2021 View substance registered dossier
(3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate
701-382-8 - Active Intermediate Joint Intermediate use only 09-04-2021 View substance registered dossier
(3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride
813-550-9 486459-71-6 Active Intermediate Joint Intermediate use only 28-02-2022 View substance registered dossier
(3R)-3-methyl-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl]pent-1-en-3-ol
637-366-1 596-85-0 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
(3R)-3-methylpiperazin-2-one
693-438-2 922178-61-8 Active Intermediate Individual Intermediate use only 30-05-2021 View substance registered dossier
(3R)-4[(2.4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one
- - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl bis(4-hydroxybenzoate)
606-059-4 185756-31-4 Active Intermediate Joint Intermediate use only 13-12-2017 View substance registered dossier
(3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol
856-563-5 1355049-94-3 Active Intermediate Joint Intermediate use only 24-08-2020 View substance registered dossier
(3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one
851-368-1 55094-52-5 Active Intermediate Joint Intermediate use only 10-09-2020 View substance registered dossier
(3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-ol
857-989-4 16838-89-4 Active Intermediate Joint Intermediate use only 01-09-2020 View substance registered dossier
(3R,4R,5S)-4-amino-5-azido-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester
805-634-9 204255-04-9 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
(3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid
820-324-3 1428243-24-6 Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active (2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol 667-304-9 6564-72-3 2020 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (2S,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-ol 667-304-9 6564-72-3 2019 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1) 947-432-4 - 2018; 2020 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2) 954-871-5 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate 942-044-1 - 2017 View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (2S,3S,4R)-3-ethyl-4-hydroxy-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate 813-641-3 1799733-43-9 - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate 938-481-2 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2S,4aR)-1,1,5,5-tetramethyl-1,3,4,5,6,7-hexahydro-2H-2,4a-methanonaphthalen-7-ol 942-036-8 645413-57-6 2020 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one;5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one 423-090-7 156732-13-7 2011; 2018 View substance registered dossier
ITELYUM Purification S.P.A. Via S. Intini n. 2 27015 Landriano (PV) Italy Italy Active (2S,4Z)-5-amino-2-(dibenzylamino)-1,6-diphenylhex-4-en-3-one;5-amino-[2S-di(methylphenyl)amino]-1,6-diphenyl-4Z-hexen-3-one 423-090-7 156732-13-7 2014 View substance registered dossier
[Confidential] - - - (2S,5S,32S)-5-{[(5S,8S,11S,14S,17S)-11-[(2R)-BUTAN-2-YL]-8-{4-[(TERT-BUTOXYCARBONYL)AMINO]BUTYL}-5-(2-TERT-BUTOXY-2-OXOETHYL)-1-(9H-FLUOREN-9-YL)-14-METHYL-3,6,9,12,15,18-HEXAOXO-17-{3-OXO-3-[(TRIPHENYLMETHYL)AMINO]PROPYL}-2-OXA-4,7,10,13,16-PENTAAZAOCTADECAN-18-YL]AMINO}-32-(TERT-BUTOXYCARBONYL)-2,55,55-TRIMETHYL-4,11,20,29,34,53-HEXAOXO-13,16,22,25,54-PENTAOXA-3,10,19,28,33-PENTAAZAHEXAPENTACONTAN-1-OIC ACID 954-943-6 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 2018 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 - View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy Italy Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active (2S-cis)-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-799-0 42399-49-5 2018 View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active (2S-cis)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 255-795-9 42399-40-6 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Active (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid 279-393-8 80082-65-1 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (2S-trans)-3-amino-2-methyl-4-oxoazetidine-1-sulphonic acid 279-393-8 80082-65-1 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (2Z)-7-chloro-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid 618-065-4 877674-77-6 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2α,6α,11R*)-3-benzyl-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol hydrobromide 248-106-8 26918-40-1 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (3,3-diethoxy-1-propenyl)benzene 230-467-8 7148-78-9 - View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (3,4-diethoxyphenyl)acetonitrile 248-479-7 27472-21-5 2022 View substance registered dossier
[Confidential] - - - (3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane) 951-684-0 - - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active (3-acetyloxy-5-carbonochloridoylphenyl) acetate 855-283-0 39192-49-9 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active (3-bromopropyl)benzene 211-294-7 637-59-2 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (3-bromopropyl)benzene 211-294-7 637-59-2 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide 629-007-2 17857-14-6 - View substance registered dossier
Ricardo Nederland BV Catharijnesingel 33 3511 GC Utrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)dimethyloctadecylammonium chloride 221-083-1 3001-63-6 2021 View substance registered dossier
Lubrizol Advanced Materials Europe B.V.B.A Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium Belgium Active (3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride 255-578-9 41892-01-7 - View substance registered dossier
DOW BENELUX B.V. OR-3 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride 255-578-9 41892-01-7 - View substance registered dossier
Ricardo Nederland BV Catharijnesingel 33 3511 GC Utrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)dodecyldimethylammonium chloride 255-578-9 41892-01-7 2018 View substance registered dossier
Clariant Produkte (Deutschland) GmbH Am Unisys-Park 1 65843 Sulzbach am Taunus Germany Germany Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
TSafeE GmbH Landwehrpl 6 66111 Saarbrücken Germany Germany Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Ricardo Nederland BV Catharijnesingel 33 3511 GC Utrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2011; 2021 View substance registered dossier
Sachem Europe BV Van Voordenpark 15 5301 KP Zaltbommel Gelderland Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2010; 2014 View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Ingredion Germany GmbH Gruner Deich 110 20097 Hamburg Germany Germany Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Nalco Limited P.O. Box 11, Winnington Avenue, CW8 4DX Northwich, Cheshire United Kingdom United Kingdom No longer Valid (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2021 View substance registered dossier
Ashland Services BV (0311) Noordweg 9 3336 LH Zwijndrecht Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Chemigate Oy Simpsiöntie 682 62100 Lapua Finland Finland Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
DOW BENELUX B.V. - OR1 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2012 View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
ROQUETTE Frères 1 rue de la haute loge 62136 LESTREM Cedex France France Cease Manufacture (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 2021 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (3-chloro-2-hydroxypropyl)trimethylammonium chloride 222-048-3 3327-22-8 - View substance registered dossier
Eburon Organics BVBA Gentstraat 58 8760 Meulebeke West-Vlaanderen Belgium Belgium Active (3-chloroprop-1-enyl)benzene 220-246-4 2687-12-9 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (3-chloropropyl)benzene 203-210-2 104-52-9 - View substance registered dossier
SYNTHEXIM 1 Quai d'Amérique 62 100 calais France France Active (3-chloropropyl)benzene 203-210-2 104-52-9 - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active (3-chloropropyl)benzene 203-210-2 104-52-9 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (3-chloropropyl)diethoxymethylsilane 236-828-6 13501-76-3 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (3-chloropropyl)diethoxymethylsilane 236-828-6 13501-76-3 2015 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (3-chloropropyl)methoxydimethylsilane 242-055-5 18171-14-7 - View substance registered dossier
R.P. Chem srl Via San Michele 47 31032 Casale sul Sile Treviso Italy Italy Active (3-cyano-2-hydroxypropyl)trimethylammonium chloride 242-684-5 18933-33-0 2019 View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (3-methoxyphenyl)acetonitrile 243-428-5 19924-43-7 - View substance registered dossier
S.I.M.S. S.r.l. Località Filarone 50066 Reggello (FI) Italy Italy Active (3-methyl-1,4-dioxo-2-naphthyl) 4-nitrobenzoate 604-586-4 14748-93-7 2019 View substance registered dossier
Miltitz Aromatics GmbH Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany Germany Active (3-Methyl-but-2-enyloxy)-benzol 846-080-8 14309-15-0 - View substance registered dossier
[Confidential] - - - (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate 813-124-2 1061337-51-6 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (3aR,4R,6R,6aR)-4-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-6-(hydroxymethyl)-2,2-dimethyl-6,6a-dihydro-3aH-furo[3,4-d][1,3]dioxole-4-carbonitrile 857-886-4 1191237-80-5 - View substance registered dossier
CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd. TO Utca 1-5 POB 110 1325 BUDAPEST Ujpest Hungary Hungary Active (3aR,4S,5R,6aS)-(-)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one 608-721-8 32233-40-2 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (3aα,4α,7α,7aα)-octahydro-4,7-methano-1H-indene 220-586-3 2825-83-4 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (3E)-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pent-3-en-2-one 948-348-0 208034-56-4 2019 View substance registered dossier
Givaudan France Fragrances SA 19-23, Voie des Bans, B.P. 98 95102 Argenteuil France France Active (3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-ol 810-303-7 459-89-2 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active (3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-ol 810-303-7 459-89-2 2018 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine 836-285-0 125349-37-3 2021 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (3R)-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-amine 836-285-0 125349-37-3 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate 701-382-8 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one hydrochloride 813-550-9 486459-71-6 2022 View substance registered dossier
[Confidential] - - - (3R)-3-methyl-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl]pent-1-en-3-ol 637-366-1 596-85-0 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Cease Manufacture (3R)-3-methyl-5-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydronaphthalen-1-yl]pent-1-en-3-ol 637-366-1 596-85-0 2020 View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-3-methylpiperazin-2-one 693-438-2 922178-61-8 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-4[(2.4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one - - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl bis(4-hydroxybenzoate) 606-059-4 185756-31-4 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 856-563-5 1355049-94-3 2021 View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (3R,4R,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)tetrahydrofuran-2-ol 856-563-5 1355049-94-3 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 2020 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (3R,4R,5R)-3,4-bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one 851-368-1 55094-52-5 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-ol 857-989-4 16838-89-4 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active (3R,4R,5S)-4-amino-5-azido-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 805-634-9 204255-04-9 - View substance registered dossier
[Confidential] - - - (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylic acid 820-324-3 1428243-24-6 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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