Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium)hemisulphate
926-418-1 - Active Intermediate Individual Intermediate use only 09-05-2018 View substance registered dossier
4-(2-methylpropyl)benzaldehyde
464-400-0 - Active NONS Joint Tonnage data confidential 22-07-2014 View substance registered dossier
4-(4'-Trifluoromethylphenyl)benzaldehyde
473-430-3 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol
919-822-4 - Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol
917-991-9 - Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid
918-019-6 - Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene
430-860-6 - Active NONS Individual Tonnage data confidential 05-11-2019 View substance registered dossier
4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
954-921-6 - Active Full Joint ≥ 0 to < 10 tonnes 17-12-2021 View substance registered dossier
4-(5-Ethyl-tetrahydropyran-2-yl)-phenol
921-114-5 - Active Full Joint ≥ 0 to < 10 tonnes 23-10-2020 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
4-(5-Propyl-tetrahydropyran-2-yl)-phenol
919-949-5 - Active Full Joint ≥ 0 to < 10 tonnes 17-12-2021 View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate
951-814-6 - Active Intermediate Individual Intermediate use only 03-01-2020 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active Full Joint ≥ 1 to < 10 tonnes 21-05-2019 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde
942-738-4 - Active Full Joint ≥ 1 to < 10 tonnes 07-12-2018 View substance registered dossier
4-(Methoxycarbonyl)-2-methylthiophen-3-ammonium chloride
619-800-1 - Active Intermediate Joint Intermediate use only 06-06-2019 View substance registered dossier
4-(trans-4-Propylcyclohexyl)-1-bromobenzene
485-340-1 - Active Intermediate Joint Intermediate use only 19-11-2019 View substance registered dossier
4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE
458-850-7 - Active NONS Joint Tonnage data confidential 23-05-2018 View substance registered dossier
4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid
423-750-4 - Active NONS Individual Tonnage data confidential 11-04-2012 View substance registered dossier
4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide
- - Active Full Individual ≥ 1 to < 10 tonnes 05-10-2011 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate
- - Active Full Joint Tonnage data confidential 04-12-2017 View substance registered dossier
4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
928-806-6 - Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - 4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium)hemisulphate 926-418-1 - - View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr.13 40210 Duesseldorf Germany Germany Active 4-(2-methylpropyl)benzaldehyde 464-400-0 - 2014 View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr. 13 40210 Duesseldorf Germany Germany Active 4-(2-methylpropyl)benzaldehyde 464-400-0 - 2014 View substance registered dossier
- - - - 4-(4'-Trifluoromethylphenyl)benzaldehyde 473-430-3 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol 919-822-4 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol 917-991-9 - - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active 4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid 918-019-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene 430-860-6 - 2019 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide 954-921-6 - 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Ethyl-tetrahydropyran-2-yl)-phenol 921-114-5 - 2020 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - 2016 View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom No longer Valid 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Propyl-tetrahydropyran-2-yl)-phenol 919-949-5 - 2021 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate 951-814-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde 942-738-4 - 2018 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-(Methoxycarbonyl)-2-methylthiophen-3-ammonium chloride 619-800-1 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-(Methoxycarbonyl)-2-methylthiophen-3-ammonium chloride 619-800-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - 2018; 2019 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE 458-850-7 - 2018 View substance registered dossier
King Industries International Science Park 402 1098 XH Amsterdam Amsterdam Netherlands Netherlands Active 4-[(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)(3-octyloxypropyl)amino]-4-oxobutyric acid;reaction mass of: 4-[(3-decyloxypropyl)(3-isobutoxy-1-isobutoxycarbonyl-3-oxopropyl)amino]-4-oxobutyric acid 423-750-4 - 2012 View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS Boulevard Dambourney 76350 Oissel France France Active 4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide - - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Rolic Technologies B.V. Luchthavenweg 10 5657 EB Eindhoven Netherlands Netherlands Active 4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate - - - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile 928-806-6 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

EU Privacy Disclaimer

This website uses cookies to ensure you get the best experience on our websites.