Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
1,4-dioxan-2-one
608-477-2 3041-16-5 Active Full Joint ≥ 0 to < 10 tonnes 24-05-2019 View substance registered dossier
1,4-dioxane
204-661-8 123-91-1 Active Full Joint ≥ 1 000 to < 10 000 tonnes 04-03-2022 View substance registered dossier
1,4-dioxane-2,5-dione
207-954-9 502-97-6 Active Full Joint ≥ 10 to < 100 tonnes 24-03-2020 View substance registered dossier
1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3R,6R)-
603-436-5 13076-17-0 Active Full Joint ≥ 1 000 to < 10 000 tonnes 26-07-2018 View substance registered dossier
1,4-dithiane-2,5-diol
254-751-6 40018-26-6 Active Intermediate Joint Intermediate use only 21-12-2017 View substance registered dossier
1,4-divinylbenzene
203-266-8 105-06-6 Active Full Joint ≥ 1 to < 10 tonnes 27-05-2018 View substance registered dossier
1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)-2,3,4,6,7,8-hexahydro-, oxime, (5E)-
700-700-2 1369492-55-6 Active Intermediate Joint Intermediate use only 11-12-2020 View substance registered dossier
1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)octahydro-8-hydroxy-
941-628-3 1263184-87-7 Active Intermediate Joint Intermediate use only 14-12-2020 View substance registered dossier
1,4-Methanonaphthalene-5,8-dione, 9-(dichloromethylene)-1,4,4a,8a-tetrahydro-
807-377-8 1263184-85-5 Active Intermediate Joint Intermediate use only 21-08-2017 View substance registered dossier
1,4-Methanonaphthalene-5,8-dione, 9-(dichloromethylene)octahydro-, (1R,4S,4aR,8aS)-rel-
700-729-0 1369500-14-0 Active Intermediate Joint Intermediate use only 08-12-2020 View substance registered dossier
1,4-Naphthalenedione, 2-[[trans-4-(1,1-dimethylethyl)cyclohexyl]methyl]-
920-399-3 1184761-65-6 No longer Valid Intermediate Joint No longer valid 27-03-2017 View substance registered dossier
1,4-naphthoquinone
204-977-6 130-15-4 Active Full Joint ≥ 10 to < 100 tonnes 24-02-2021 View substance registered dossier
1,4-naphthoquinone
204-977-6 130-15-4 Cease Manufacture Intermediate Joint Cease manufacture 24-11-2017 View substance registered dossier
1,4-α-glucan branching enzyme
849-290-8 9001-97-2 Active Full Joint ≥ 1 000 to < 10 000 tonnes 13-04-2021 View substance registered dossier
1,4:3,6-dianhydro-2,5-di-O-methyl-D-glucitol
226-159-8 5306-85-4 Active Full Joint ≥ 10 to < 100 tonnes 05-12-2019 View substance registered dossier
1,4:3,6-dianhydro-D-glucitol
211-492-3 652-67-5 Active Full Joint ≥ 1 000 to < 10 000 tonnes 25-05-2018 View substance registered dossier
1,5,10-trimethylcyclododeca-1,5,9-triene
244-218-6 21115-77-5 Active Intermediate Joint Intermediate use only 22-10-2019 View substance registered dossier
1,5,10-trimethylcyclododeca-1,5,9-triene, epoxidised
945-746-6 - Active Full Joint ≥ 1 to < 10 tonnes 30-05-2018 View substance registered dossier
1,5-bis(cyclohexylamino)anthraquinone
240-093-7 15958-68-6 Active Full Joint ≥ 1 to < 10 tonnes 02-12-2021 View substance registered dossier
1,5-Cyclopentadecanedione, 3-methyl-
606-859-3 21890-10-8 Active Intermediate Joint Intermediate use only 31-05-2013 View substance registered dossier
1,5-diacetylperhydro-1,3,5-triazine-2,4-dione
DADHT; NC-4
405-345-4 86320-44-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
1,5-dibromopentane
203-849-7 111-24-0 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
1,5-dichloro-2-(1-methylethoxy)-4-nitrobenzene
255-259-4 41200-97-9 Cease Manufacture Intermediate Joint Cease manufacture 27-02-2013 View substance registered dossier
1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-yl acetate
296-417-2 92671-67-5 Active Intermediate Joint Intermediate use only 11-09-2019 View substance registered dossier
1,5-dimethyl-1-vinylhept-4-enyl acetate
263-336-9 61931-80-4 Active Full Joint ≥ 10 to < 100 tonnes 18-10-2019 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Johnson & Johnson International Leonardo da Vincilaan 15, 1831 1831 Machelen Belgium Belgium Active 1,4-dioxan-2-one 608-477-2 3041-16-5 2019 View substance registered dossier
Penman Consulting bvba 15 Avenue des Arts 10 B-1210 Brussels Belgium Belgium Active 1,4-dioxane 204-661-8 123-91-1 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 1,4-dioxane 204-661-8 123-91-1 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 1,4-dioxane 204-661-8 123-91-1 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 1,4-dioxane 204-661-8 123-91-1 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 1,4-dioxane 204-661-8 123-91-1 2010; 2012; 2020; 2022 View substance registered dossier
SYNTHESIA TECHNOLOGY EUROPE S.L.U C/ Argent, 3 08755 Castellbisbal (Barcelona) Spain Spain Active 1,4-dioxane 204-661-8 123-91-1 2021 View substance registered dossier
Labcorp Development SA 148 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain Spain Active 1,4-dioxane 204-661-8 123-91-1 2021 View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture 1,4-dioxane 204-661-8 123-91-1 2019 View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active 1,4-dioxane 204-661-8 123-91-1 2020 View substance registered dossier
PURAC Biochem Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active 1,4-dioxane-2,5-dione 207-954-9 502-97-6 - View substance registered dossier
ITV Denkendorf Produktservice GmbH Koerschtalstr. 26 73770 Denkendorf Germany Germany Active 1,4-dioxane-2,5-dione 207-954-9 502-97-6 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 1,4-dioxane-2,5-dione 207-954-9 502-97-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1,4-dioxane-2,5-dione 207-954-9 502-97-6 - View substance registered dossier
Johnson & Johnson International Leonardo da Vincilaan 15, 1831 1831 Machelen Belgium Belgium Active 1,4-dioxane-2,5-dione 207-954-9 502-97-6 2018 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3R,6R)- 603-436-5 13076-17-0 - View substance registered dossier
PURAC Biochem Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3R,6R)- 603-436-5 13076-17-0 2011; 2015 View substance registered dossier
Total Corbion PLA bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active 1,4-Dioxane-2,5-dione, 3,6-dimethyl-, (3R,6R)- 603-436-5 13076-17-0 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 1,4-dithiane-2,5-diol 254-751-6 40018-26-6 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 1,4-dithiane-2,5-diol 254-751-6 40018-26-6 2017 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 223 63 Lund Sweden Sweden Active 1,4-divinylbenzene 203-266-8 105-06-6 2018 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)-2,3,4,6,7,8-hexahydro-, oxime, (5E)- 700-700-2 1369492-55-6 2014; 2018; 2020 View substance registered dossier
[Confidential] - - - 1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)-2,3,4,6,7,8-hexahydro-, oxime, (5E)- 700-700-2 1369492-55-6 - View substance registered dossier
[Confidential] - - - 1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)octahydro-8-hydroxy- 941-628-3 1263184-87-7 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)octahydro-8-hydroxy- 941-628-3 1263184-87-7 2021 View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid 1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)octahydro-8-hydroxy- 941-628-3 1263184-87-7 2021 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active 1,4-Methanonaphthalen-5(1H)-one, 9-(dichloromethylene)octahydro-8-hydroxy- 941-628-3 1263184-87-7 2019 View substance registered dossier
[Confidential] - - - 1,4-Methanonaphthalene-5,8-dione, 9-(dichloromethylene)-1,4,4a,8a-tetrahydro- 807-377-8 1263184-85-5 - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid 1,4-Methanonaphthalene-5,8-dione, 9-(dichloromethylene)octahydro-, (1R,4S,4aR,8aS)-rel- 700-729-0 1369500-14-0 2021 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active 1,4-Methanonaphthalene-5,8-dione, 9-(dichloromethylene)octahydro-, (1R,4S,4aR,8aS)-rel- 700-729-0 1369500-14-0 2019 View substance registered dossier
[Confidential] - - - 1,4-Methanonaphthalene-5,8-dione, 9-(dichloromethylene)octahydro-, (1R,4S,4aR,8aS)-rel- 700-729-0 1369500-14-0 - View substance registered dossier
Robinson Brothers Ltd Phoenix Street B70 0AH West Bromwich West Midlands United Kingdom United Kingdom No longer Valid 1,4-Naphthalenedione, 2-[[trans-4-(1,1-dimethylethyl)cyclohexyl]methyl]- 920-399-3 1184761-65-6 2021 View substance registered dossier
BCS Only Representative Services Ltd 020 Pembroke House 30 Upper Pembroke Street Dublin 2 Dublin Ireland Ireland Active 1,4-naphthoquinone 204-977-6 130-15-4 2018; 2021 View substance registered dossier
IVICT Europe GmbH Kennedydamm 19 40476 Düsseldorf Germany Germany Cease Manufacture 1,4-naphthoquinone 204-977-6 130-15-4 2019 View substance registered dossier
Novozymes A/S Krogshoejvej 36 2880 Bagsvaerd Denmark Denmark Active 1,4-α-glucan branching enzyme 849-290-8 9001-97-2 - View substance registered dossier
knoell Germany – OR – E11 Konrad-Zuse-Ring 25 68163 Mannheim Germany Germany Active 1,4:3,6-dianhydro-2,5-di-O-methyl-D-glucitol 226-159-8 5306-85-4 - View substance registered dossier
INFOTOX - Consultores de Riscos Ambientais e Tecnológicos Lda. Rua de Moscavide loja 6D 1990-160 Lisbon Portugal Portugal Active 1,4:3,6-dianhydro-2,5-di-O-methyl-D-glucitol 226-159-8 5306-85-4 - View substance registered dossier
REACHLaw Ltd. (acting as OR for Novaphene Specialities Pvt. Ltd.) Vänrikinkuja 3JK 21 02600 Espoo Finland Finland Active 1,4:3,6-dianhydro-2,5-di-O-methyl-D-glucitol 226-159-8 5306-85-4 - View substance registered dossier
Croda EU B.V. (OR1) Buurtje 1 2802 BE Gouda Netherlands Netherlands Active 1,4:3,6-dianhydro-2,5-di-O-methyl-D-glucitol 226-159-8 5306-85-4 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 1,4:3,6-dianhydro-D-glucitol 211-492-3 652-67-5 - View substance registered dossier
DHW Deutsche Hydrierwerke GmbH Rodleben Brambacher Weg 1 06861 Dessau - Rosslau Saxony - Anhalt Germany Germany Active 1,4:3,6-dianhydro-D-glucitol 211-492-3 652-67-5 - View substance registered dossier
ROQUETTE Frères 1 rue de la haute loge 62136 LESTREM Cedex France France Active 1,4:3,6-dianhydro-D-glucitol 211-492-3 652-67-5 - View substance registered dossier
Miltitz Aromatics GmbH Chemiepark Bitterfeld-Wolfen Riechstoffstrasse 1 06803 Bitterfeld-Wolfen Germany Germany Active 1,5,10-trimethylcyclododeca-1,5,9-triene 244-218-6 21115-77-5 2018 View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 1,5,10-trimethylcyclododeca-1,5,9-triene 244-218-6 21115-77-5 2019 View substance registered dossier
[Confidential] - - - 1,5,10-trimethylcyclododeca-1,5,9-triene, epoxidised 945-746-6 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active 1,5,10-trimethylcyclododeca-1,5,9-triene, epoxidised 945-746-6 - 2017 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active 1,5-bis(cyclohexylamino)anthraquinone 240-093-7 15958-68-6 - View substance registered dossier
[Confidential] - - - 1,5-bis(cyclohexylamino)anthraquinone 240-093-7 15958-68-6 - View substance registered dossier
[Confidential] - - - 1,5-Cyclopentadecanedione, 3-methyl- 606-859-3 21890-10-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 1,5-diacetylperhydro-1,3,5-triazine-2,4-dione 405-345-4 86320-44-7 - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active 1,5-dibromopentane 203-849-7 111-24-0 - View substance registered dossier
RHODIA OPERATIONS 9 rue des Cuirassiers Immeuble Silex 2 Solvay 69003 LYON France France Cease Manufacture 1,5-dichloro-2-(1-methylethoxy)-4-nitrobenzene 255-259-4 41200-97-9 2016 View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active 1,5-dihydro-3-isopropyl-8-methyl-[1,3]dioxepino[5,6-c]pyridin-9-yl acetate 296-417-2 92671-67-5 2012; 2013; 2019 View substance registered dossier
DSM Nutritional Products GmbH - OR1 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active 1,5-dimethyl-1-vinylhept-4-enyl acetate 263-336-9 61931-80-4 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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