Registered substances

Registered substances

Registered substances

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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2-bromopalmitic acid
242-137-0 18263-25-7 Active Intermediate Joint Intermediate use only 26-03-2019 View substance registered dossier
2-bromopentane
203-521-3 107-81-3 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
2-bromopropane
200-855-1 75-26-3 Active Intermediate Joint Intermediate use only 11-12-2012 View substance registered dossier
2-bromopropane
200-855-1 75-26-3 Active Intermediate Individual Intermediate use only 07-05-2013 View substance registered dossier
2-bromopropene
209-185-4 557-93-7 Active Intermediate Joint Intermediate use only 30-04-2020 View substance registered dossier
2-bromopropionic acid
209-947-6 598-72-1 Active Intermediate Joint Intermediate use only 10-08-2020 View substance registered dossier
2-bromopropionyl bromide
209-261-7 563-76-8 Active Intermediate Joint Intermediate use only 06-06-2018 View substance registered dossier
2-bromopropionyl chloride
230-466-2 7148-74-5 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
2-bromopyridine
203-641-6 109-04-6 Active Intermediate Joint Intermediate use only 16-06-2017 View substance registered dossier
2-bromospiro-9,9'-bifluorene
605-609-0 171408-76-7 Active Intermediate Joint Intermediate use only 07-02-2020 View substance registered dossier
2-bromothiophene
213-699-4 1003-09-4 Active Intermediate Joint Intermediate use only 11-01-2019 View substance registered dossier
2-Butanol, 2-methyl-, lithium salt (1:1)
485-110-0 53535-81-2 Active Intermediate Joint Intermediate use only 18-06-2013 View substance registered dossier
2-Buten-1-ol, 2-methyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-, (2E)-
813-338-6 106155-02-6 Active Intermediate Joint Intermediate use only 06-06-2017 View substance registered dossier
2-Buten-1-one, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)-
616-378-0 767340-03-4 Active Intermediate Individual Intermediate use only 08-10-2012 View substance registered dossier
2-Butenal, 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-, (2E)-
801-014-7 179107-88-1 Active Intermediate Joint Intermediate use only 30-05-2013 View substance registered dossier
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-
923-981-5 850140-72-6 Active Intermediate Individual Intermediate use only 20-07-2015 View substance registered dossier
2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)-
811-237-1 698387-09-6 Active Intermediate Joint Intermediate use only 09-11-2015 View substance registered dossier
2-Butene, 1,1,4,4-tetramethoxy-
900-110-7 5370-08-1 Active Intermediate Joint Intermediate use only 20-01-2020 View substance registered dossier
2-Butene, chlorinated, epoxidized, distn. residues
304-783-2 94279-39-7 Active Intermediate Individual Intermediate use only 10-02-2010 View substance registered dossier
2-Butene-1,4-diol, 1,4-diacetate, (2Z)-
607-674-0 25260-60-0 Active Intermediate Joint Intermediate use only 06-12-2019 View substance registered dossier
2-Butenedioic acid (2E)-, monooctadecyl ester
605-713-6 1741-93-1 Active Intermediate Joint Intermediate use only 23-08-2017 View substance registered dossier
2-Butenedioic acid (2Z)-, reaction products with ammonium di-.mu.3-hydroxyhexacosa-.mu.-oxododecaoxododecatungstate(6-) (6:1), ammonium octa-.mu.-oxodi-.mu.3-oxodi-.mu.4-oxododecaoxoheptamolybdate(6-) (6:1), nickel(2+) nitrate (1:2) and nickel(2+) sulfate (1:1)
800-777-3 1351378-24-9 Active Intermediate Joint Intermediate use only 02-09-2014 View substance registered dossier
2-Butenedioic acid, 2-methyl-, 1,4-bis(2-ethylhexyl) ester, (2Z)-
807-715-4 1354569-12-2 Active Intermediate Joint Intermediate use only 09-05-2018 View substance registered dossier
2-Butenedioic acid, 2-methyl-, 1,4-diethyl ester, (2Z)-
813-684-8 691-83-8 Active Intermediate Joint Intermediate use only 13-03-2017 View substance registered dossier
2-Butenoic acid, 3-[(1-carboxyethyl)amino]-, 1-ethyl ester, monopotassium salt, [S-(Z)]-
609-057-1 35052-92-7 Active Intermediate Joint Intermediate use only 30-01-2015 View substance registered dossier
2-Butenoic acid, 3-[(carboxymethyl)amino]-, 1-ethyl ester, monopotassium salt, (2Z)-
615-497-5 71809-65-9 Active Intermediate Joint Intermediate use only 10-06-2016 View substance registered dossier
2-Butenoic acid, 3-amino-, 1-methylethyl ester
604-269-0 14205-46-0 Active Intermediate Joint Intermediate use only 21-08-2018 View substance registered dossier
2-Butenoic acid, 3-amino-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl ester
802-095-1 90096-33-6 Active Intermediate Joint Intermediate use only 24-07-2019 View substance registered dossier
2-Butenoic acid, 3-methyl-4-oxo-, ethyl ester, (2E)-
690-663-8 62054-49-3 Active Intermediate Joint Intermediate use only 05-12-2014 View substance registered dossier
2-Butenoic acid, 3-methyl-4-oxo-, methyl ester, (2E)-
609-870-1 40835-18-5 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
2-Butenoic acid, 4-(diethoxyphosphinyl)-2-methyl-, ethyl ester
601-818-6 122009-11-4 Active Intermediate Joint Intermediate use only 10-03-2021 View substance registered dossier
2-Butenoic acid, 4-(dimethylamino)-, ethyl ester, (2E)-, (2Z)-2-butenedioate (1:1)
941-772-7 1690340-79-4 Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
2-butenoic anhydride
210-807-1 623-68-7 Active Intermediate Joint Intermediate use only 09-05-2018 View substance registered dossier
2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride
SR 48001 A
424-560-4 151257-01-1 Active Intermediate Individual Intermediate use only 10-11-2010 View substance registered dossier
2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride
SR 48001 A
424-560-4 151257-01-1 Active Intermediate Joint Intermediate use only 15-11-2012 View substance registered dossier
2-Butyl-3-(4-chlorobenzyl)-1,3-diazaspiro[4.4]non-1-en-4-one and (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-methanesulfonic acid
700-176-5 - Active Intermediate Individual Intermediate use only 25-01-2011 View substance registered dossier
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Active Intermediate Individual Intermediate use only 31-08-2011 View substance registered dossier
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Active Intermediate Individual Intermediate use only 02-02-2011 View substance registered dossier
2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole
TRITYL-LOSARTAN; TRITYL-MK0954
412-420-5 133909-99-6 Active Intermediate Individual Intermediate use only 02-08-2011 View substance registered dossier
2-butyl-4-chloro-5-formylimidazole
2-BUTYL-4-CHLORO-5-FORMYLIMIDAZOLE; BCFI
410-260-0 83857-96-9 Active Intermediate Joint Intermediate use only 04-09-2018 View substance registered dossier
2-butylbenzofuran
224-250-7 4265-27-4 Active Intermediate Joint Intermediate use only 05-04-2022 View substance registered dossier
2-butynoic acid
209-695-7 590-93-2 Active Intermediate Individual Intermediate use only 10-08-2020 View substance registered dossier
2-butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one
425-150-8 94723-86-1 Active Intermediate Joint Intermediate use only 09-07-2014 View substance registered dossier
2-carboxymethyl-5-methoxy-benzoic acid
651-248-7 52962-25-1 Active Intermediate Individual Intermediate use only 26-04-2018 View substance registered dossier
2-chloro-1,1-diethoxyethane
210-695-4 621-62-5 Active Intermediate Joint Intermediate use only 09-11-2016 View substance registered dossier
2-chloro-1,1-dimethoxyethane
202-624-0 97-97-2 Active Intermediate Joint Intermediate use only 01-04-2021 View substance registered dossier
2-chloro-1-(4-methylphenyl)ethan-1-one
840-211-2 4209-24-9 Active Intermediate Individual Intermediate use only 20-05-2021 View substance registered dossier
2-chloro-1-[(4-fluorophenyl)methyl]-1H-benzimidazole
284-624-0 84946-20-3 Active Intermediate Joint Intermediate use only 09-10-2017 View substance registered dossier
2-Chloro-1-fluoro-4-(trifluoromethyl)benzene
616-586-1 78068-85-6 Active Intermediate Joint Intermediate use only 21-01-2021 View substance registered dossier
2-chloro-2',6'-dimethylacetanilide
214-460-7 1131-01-7 Active Intermediate Joint Intermediate use only 29-03-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active 2-bromopalmitic acid 242-137-0 18263-25-7 - View substance registered dossier
Vynova PPC SAS 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France France Active 2-bromopentane 203-521-3 107-81-3 - View substance registered dossier
Only representative (No publishable name) - - Active 2-bromopropane 200-855-1 75-26-3 - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Cease Manufacture 2-bromopropane 200-855-1 75-26-3 2016 View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid 2-bromopropane 200-855-1 75-26-3 2021 View substance registered dossier
NetSun EU B.V. Blaak 40, Fifth Floor 3011 TA Rotterdam Netherlands Netherlands Cease Manufacture 2-bromopropane 200-855-1 75-26-3 2016 View substance registered dossier
Vynova PPC SAS 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France France Active 2-bromopropane 200-855-1 75-26-3 2012 View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 2-bromopropane 200-855-1 75-26-3 - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active 2-bromopropene 209-185-4 557-93-7 - View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active 2-bromopropene 209-185-4 557-93-7 - View substance registered dossier
Vynova PPC SAS 95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France France Active 2-bromopropionic acid 209-947-6 598-72-1 2013 View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active 2-bromopropionic acid 209-947-6 598-72-1 - View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid 2-bromopropionic acid 209-947-6 598-72-1 2021 View substance registered dossier
B-Lands Consulting (811725-2) 5 Place Robert Schuman - BP 1516 38025 Grenoble France France France Active 2-bromopropionyl bromide 209-261-7 563-76-8 - View substance registered dossier
BENECHIM René Magritte 163 7860 Lessines Belgium Belgium Active 2-bromopropionyl bromide 209-261-7 563-76-8 - View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid 2-bromopropionyl bromide 209-261-7 563-76-8 2021 View substance registered dossier
S.I.M.S. S.r.l. Località Filarone 50066 Reggello (FI) Italy Italy Active 2-bromopropionyl chloride 230-466-2 7148-74-5 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-bromopyridine 203-641-6 109-04-6 - View substance registered dossier
Jubilant Lifesciences NV Axxes Business Park - Guldensporenpark 22 - block C 9820 Merelbeke Belgium Belgium Active 2-bromopyridine 203-641-6 109-04-6 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 2-bromospiro-9,9'-bifluorene 605-609-0 171408-76-7 2020 View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active 2-bromothiophene 213-699-4 1003-09-4 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2-bromothiophene 213-699-4 1003-09-4 - View substance registered dossier
Albemarle Germany GmbH Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany Germany Active 2-Butanol, 2-methyl-, lithium salt (1:1) 485-110-0 53535-81-2 2009; 2010; 2013 View substance registered dossier
FMC Chemicals Ltd Wirral International Business Park Commercial Road CH62 3NL Bromborough Wirral United Kingdom United Kingdom No longer Valid 2-Butanol, 2-methyl-, lithium salt (1:1) 485-110-0 53535-81-2 2021 View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 2-Buten-1-ol, 2-methyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-, (2E)- 813-338-6 106155-02-6 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-Buten-1-one, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)- 616-378-0 767340-03-4 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active 2-Butenal, 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-, (2E)- 801-014-7 179107-88-1 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)- 923-981-5 850140-72-6 2015 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 2-Butenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2E)- 811-237-1 698387-09-6 - View substance registered dossier
[Confidential] - - - 2-Butene, 1,1,4,4-tetramethoxy- 900-110-7 5370-08-1 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 2-Butene, chlorinated, epoxidized, distn. residues 304-783-2 94279-39-7 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 2-Butene-1,4-diol, 1,4-diacetate, (2Z)- 607-674-0 25260-60-0 2012; 2019 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture 2-Butene-1,4-diol, 1,4-diacetate, (2Z)- 607-674-0 25260-60-0 2020 View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active 2-Butenedioic acid (2E)-, monooctadecyl ester 605-713-6 1741-93-1 - View substance registered dossier
GRACE GmbH In der Hollerhecke 1 67545 Worms Germany Germany Active 2-Butenedioic acid (2Z)-, reaction products with ammonium di-.mu.3-hydroxyhexacosa-.mu.-oxododecaoxododecatungstate(6-) (6:1), ammonium octa-.mu.-oxodi-.mu.3-oxodi-.mu.4-oxododecaoxoheptamolybdate(6-) (6:1), nickel(2+) nitrate (1:2) and nickel(2+) sulfate (1:1) 800-777-3 1351378-24-9 2014 View substance registered dossier
[Confidential] - - - 2-Butenedioic acid, 2-methyl-, 1,4-bis(2-ethylhexyl) ester, (2Z)- 807-715-4 1354569-12-2 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 2-Butenedioic acid, 2-methyl-, 1,4-diethyl ester, (2Z)- 813-684-8 691-83-8 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 2-Butenoic acid, 3-[(1-carboxyethyl)amino]-, 1-ethyl ester, monopotassium salt, [S-(Z)]- 609-057-1 35052-92-7 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 2-Butenoic acid, 3-[(1-carboxyethyl)amino]-, 1-ethyl ester, monopotassium salt, [S-(Z)]- 609-057-1 35052-92-7 - View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active 2-Butenoic acid, 3-[(carboxymethyl)amino]-, 1-ethyl ester, monopotassium salt, (2Z)- 615-497-5 71809-65-9 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 2-Butenoic acid, 3-[(carboxymethyl)amino]-, 1-ethyl ester, monopotassium salt, (2Z)- 615-497-5 71809-65-9 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 2-Butenoic acid, 3-[(carboxymethyl)amino]-, 1-ethyl ester, monopotassium salt, (2Z)- 615-497-5 71809-65-9 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 2-Butenoic acid, 3-amino-, 1-methylethyl ester 604-269-0 14205-46-0 2018 View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy Italy Active 2-Butenoic acid, 3-amino-, 1-methylethyl ester 604-269-0 14205-46-0 - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active 2-Butenoic acid, 3-amino-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl ester 802-095-1 90096-33-6 2019 View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active 2-Butenoic acid, 3-amino-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl ester 802-095-1 90096-33-6 2017 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active 2-Butenoic acid, 3-methyl-4-oxo-, ethyl ester, (2E)- 690-663-8 62054-49-3 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 2-Butenoic acid, 3-methyl-4-oxo-, methyl ester, (2E)- 609-870-1 40835-18-5 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 2-Butenoic acid, 4-(diethoxyphosphinyl)-2-methyl-, ethyl ester 601-818-6 122009-11-4 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active 2-Butenoic acid, 4-(diethoxyphosphinyl)-2-methyl-, ethyl ester 601-818-6 122009-11-4 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active 2-Butenoic acid, 4-(dimethylamino)-, ethyl ester, (2E)-, (2Z)-2-butenedioate (1:1) 941-772-7 1690340-79-4 2015 View substance registered dossier
WeylChem Höchst GmbH Brüningstr. 50 D-65929 Frankfurt am Main Germany Germany Active 2-butenoic anhydride 210-807-1 623-68-7 - View substance registered dossier
INKE, S.A. Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain Spain Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 - View substance registered dossier
CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd. TO Utca 1-5 POB 110 1325 BUDAPEST Ujpest Hungary Hungary Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 2010; 2012 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 2010 View substance registered dossier
Lonza Cologne GmbH - REACH Nattermannallee 1 50829 Cologne Germany Germany Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 2010 View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 2-Butyl-3-(4-chlorobenzyl)-1,3-diazaspiro[4.4]non-1-en-4-one and (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-methanesulfonic acid 700-176-5 - 2009; 2011 View substance registered dossier
Only representative (No publishable name) - - Active 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 2011 View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 2008; 2011 View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active 2-butyl-4-chloro-4,5-dihydro-5-hydroxymethyl-1-[2'-(2-triphenylmethyl-1,2,3,4-2H-tetrazol-5-yl)-1,1'-biphenyl-4-methyl]-1H-imidazole 412-420-5 133909-99-6 2011 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 2-butyl-4-chloro-5-formylimidazole 410-260-0 83857-96-9 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 2-butyl-4-chloro-5-formylimidazole 410-260-0 83857-96-9 2010; 2012; 2013 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active 2-butylbenzofuran 224-250-7 4265-27-4 2018 View substance registered dossier
Cambrex Profarmaco Milano Srl via Curiel, 34 20067 Paullo MI Italy Italy Active 2-butylbenzofuran 224-250-7 4265-27-4 2017 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 2-butylbenzofuran 224-250-7 4265-27-4 - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active 2-butynoic acid 209-695-7 590-93-2 - View substance registered dossier
[Confidential] - - - 2-butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one 425-150-8 94723-86-1 - View substance registered dossier
CSI-OR47DUB Block C Ardilaun Court 112-114 St. Stephen’s Green D02 TD28 Dublin Ireland Ireland Active 2-butyryl-3-hydroxy-5-thiocyclohexan-3-yl-cyclohex-2-en-1-one 425-150-8 94723-86-1 - View substance registered dossier
KINSY, S.L. Avda. Europa s/n Parque Industrial de Alhama 30840 Alhama de Murcia Murcia Spain Spain Active 2-carboxymethyl-5-methoxy-benzoic acid 651-248-7 52962-25-1 2018 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active 2-chloro-1,1-diethoxyethane 210-695-4 621-62-5 - View substance registered dossier
REACH24H CONSULTING GROUP (acts as the OR for PRINCECHEM(ANQING)PHARMATECH CO ., LTD.) Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 2-chloro-1,1-dimethoxyethane 202-624-0 97-97-2 2018; 2021 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active 2-chloro-1,1-dimethoxyethane 202-624-0 97-97-2 2018 View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active 2-chloro-1,1-dimethoxyethane 202-624-0 97-97-2 2016 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2-chloro-1,1-dimethoxyethane 202-624-0 97-97-2 - View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active 2-chloro-1-(4-methylphenyl)ethan-1-one 840-211-2 4209-24-9 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active 2-chloro-1-[(4-fluorophenyl)methyl]-1H-benzimidazole 284-624-0 84946-20-3 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Active 2-Chloro-1-fluoro-4-(trifluoromethyl)benzene 616-586-1 78068-85-6 - View substance registered dossier
WeylChem Griesheim GmbH Stroofstr. 27 D-65933 Frankfurt am Main Germany Germany Cease Manufacture 2-Chloro-1-fluoro-4-(trifluoromethyl)benzene 616-586-1 78068-85-6 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 2-chloro-2',6'-dimethylacetanilide 214-460-7 1131-01-7 - View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy Italy Active 2-chloro-2',6'-dimethylacetanilide 214-460-7 1131-01-7 - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 2-chloro-2',6'-dimethylacetanilide 214-460-7 1131-01-7 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active 2-chloro-2',6'-dimethylacetanilide 214-460-7 1131-01-7 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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