Registered substances

Registered substances

Registered substances

Please note:

We have successfully adapted to the latest IUCLID format, and have resumed processing dossiers since 3 March 2022. Over the coming weeks we will catch up with the backlog of submissions since 14 October 2021, and expect to have all outstanding data online in approximately one month’s time. Please be aware that any new submissions will be at the back of the processing queue, and will be correspondingly delayed before publication. We appreciate your understanding in this matter.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
Erythromycin, 9-oxime, (9Z)-
603-883-6 134931-01-4 Cease Manufacture Intermediate Individual Cease manufacture 25-10-2012 View substance registered dossier
Esterification product of castor oil and tetrahydromethyl-1,3-isobenzofuranedione
700-064-6 1059667-42-3 Cease Manufacture Full Individual Cease manufacture 27-01-2011 View substance registered dossier
estr-4-ene-3,11,17-trione cyclic 3-(1,2-ethanediylmercaptole)
920-684-2 - Cease Manufacture Full Individual Cease manufacture 04-12-2013 View substance registered dossier
Estr-4-ene-3,11,17-trione, cyclic 17-(2,2-dimethyl-1,3-propanediyl acetal) cyclic 3-(1,2-ethanediyl dithioacetal)
695-716-9 1174931-74-8 Cease Manufacture Full Joint Cease manufacture 06-11-2012 View substance registered dossier
Estr-4-ene-3,17-dione, 11-hydroxy-, (11.alpha.)-
613-901-4 6615-00-5 Cease Manufacture Full Joint Cease manufacture 23-10-2012 View substance registered dossier
Ethanol, 2,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, tetrakis(4-methylbenzenesulfonate) (salt)
614-977-1 69477-29-8 Cease Manufacture Intermediate Individual Cease manufacture 25-03-2011 View substance registered dossier
Ethanol, 2-[(3-nitropyrazolo[1,5-a]pyridin-2-yl)oxy]-
938-829-3 936103-10-5 Cease Manufacture Intermediate Joint Cease manufacture 07-07-2015 View substance registered dossier
Ethanol, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
805-296-2 102229-10-7 Cease Manufacture Intermediate Individual Cease manufacture 14-11-2013 View substance registered dossier
Ethanol, 2-butoxy-, manufacture of, by-products from
A complex mixture of oxygenated hydrocarbons produced by the distillation of residues from the manufacture of ethylene glycol monobutyl ether. It consists predominantly of a mixture of di-, tri-, tetra- and pentaethylene glycol monobutyl ethers having carbon numbers predominantly in the range C8 to C14 and boiling in the range of approximately 210°C to 310°C (410°F to 590°F).
310-287-7 161907-77-3 Cease Manufacture Full Joint Cease manufacture 24-05-2016 View substance registered dossier
Ethanol, 2-ethoxy-, manufacture of, by-products from
A complex mixture of oxygenated hydrocarbons produced by the distillation of residues from the manufacture of ethylene glycol monoethyl ether. It consists predominantly of a mixture of di-, tri-, tetra- and pentaethylene glycol monoethyl ethers having carbon numbers predominantly in the range C6 to C12 and boiling in the range of approximately 200°C to 300°C (392°F to 572°F).
310-288-2 161907-78-4 Cease Manufacture Full Joint Cease manufacture 13-04-2018 View substance registered dossier
Ethanol, 2-methoxy-, manufacture of, by-products from
A complex mixture of oxygenated hydrocarbons produced by the distillation of residues from the manufacture of ethylene glycol monomethyl ether. It consists predominantly of a mixture of di-, tri-, tetra- and pentaethylene glycol monomethyl ethers having carbon numbers predominantly in the range C5 to C11 and boiling in the range of approximately 200°C to 300°C (392°F to 572°F).
310-289-8 161907-79-5 Cease Manufacture Full Joint Cease manufacture 21-02-2012 View substance registered dossier
Ethanol, 2-methoxy-, manufacture of, by-products from, esters with boric acid
310-290-3 161907-80-8 Cease Manufacture Full Joint Cease manufacture 18-05-2016 View substance registered dossier
Ethanone, 1,1'-[1,3-propanediylbis(oxy-4,1-phenylene)]bis[2,2,2-trifluoro-, 1,1'-bis[O-(propylsulfonyl)oxime]
457-550-3 300374-81-6 Cease Manufacture NONS Joint Cease manufacture 24-06-2009 View substance registered dossier
Ethanone, 1-(1-naphthalenyl)-, oxime, (1E)-
700-765-7 100485-51-6 Cease Manufacture Intermediate Individual Cease manufacture 07-12-2012 View substance registered dossier
Ethanone, 1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro-
696-512-2 1378387-81-5 Cease Manufacture Intermediate Joint Cease manufacture 19-03-2015 View substance registered dossier
Ethanone, 1-[4-(acetyloxy)-3-[(acetyloxy)methyl]phenyl]-
607-317-9 24085-06-1 Cease Manufacture Intermediate Individual Cease manufacture 02-06-2009 View substance registered dossier
Ethanone, 1-[9-ethyl-6-(2-methylbenzoyl)-9H-carbazol-3-yl]-, 1-(O-acetyloxime)
455-590-6 478556-66-0 Cease Manufacture NONS Joint Cease manufacture 24-06-2009 View substance registered dossier
Ethanone, 2,2-dichloro-1-[5-(2-furanyl)-2,2-dimethyl-3-oxazolidinyl]-
434-800-1 121776-33-8 Cease Manufacture Full Individual Cease manufacture 05-11-2020 View substance registered dossier
Ethers, C5-6-branched alkyl Me
295-322-3 91995-60-7 Cease Manufacture Full Joint Cease manufacture 25-01-2017 View substance registered dossier
Ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]pentanoate
700-226-6 488097-90-1 Cease Manufacture Intermediate Individual Cease manufacture 16-03-2011 View substance registered dossier
ethyl (2Z)-2-[2-(4-chlorophenyl)hydrazinylidene]-3-(2,6-dichlorophenyl)-3-oxopropanoate
609-702-7 395068-96-9 Cease Manufacture Intermediate Joint Cease manufacture 04-09-2017 View substance registered dossier
ethyl 2-(2,6-dichlorobenzoyl)-3-oxobutanoate
606-828-4 217458-21-4 Cease Manufacture Intermediate Joint Cease manufacture 04-09-2017 View substance registered dossier
Ethyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate
700-551-3 179688-27-8 Cease Manufacture Intermediate Joint Cease manufacture 30-11-2012 View substance registered dossier
Ethyl 2-hydroxy-3-methylbut-3-enoate
EVERNOTE
445-780-7 33537-17-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
Ethyl 3,4-dihydroxybenzoate
223-529-0 3943-89-3 Cease Manufacture Intermediate Joint Cease manufacture 30-11-2015 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - Erythromycin, 9-oxime, (9Z)- 603-883-6 134931-01-4 - View substance registered dossier
Henkel Belgium Operations N.V. Havenlaan 16 1080 Brussels Belgium Belgium Cease Manufacture Esterification product of castor oil and tetrahydromethyl-1,3-isobenzofuranedione 700-064-6 1059667-42-3 2014 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture estr-4-ene-3,11,17-trione cyclic 3-(1,2-ethanediylmercaptole) 920-684-2 - 2019 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture Estr-4-ene-3,11,17-trione, cyclic 17-(2,2-dimethyl-1,3-propanediyl acetal) cyclic 3-(1,2-ethanediyl dithioacetal) 695-716-9 1174931-74-8 2019 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture Estr-4-ene-3,17-dione, 11-hydroxy-, (11.alpha.)- 613-901-4 6615-00-5 2019 View substance registered dossier
LABSO Chimie Fine 20, rue Jean Duvert 33920 Blanquefort France France Cease Manufacture Ethanol, 2,2',2'',2'''-[(4,8-di-1-piperidinylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakis-, tetrakis(4-methylbenzenesulfonate) (salt) 614-977-1 69477-29-8 2016 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture Ethanol, 2-[(3-nitropyrazolo[1,5-a]pyridin-2-yl)oxy]- 938-829-3 936103-10-5 2018 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Cease Manufacture Ethanol, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- 805-296-2 102229-10-7 2017 View substance registered dossier
INEOS nv Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium Belgium Cease Manufacture Ethanol, 2-butoxy-, manufacture of, by-products from 310-287-7 161907-77-3 2016 View substance registered dossier
Shell Nederland Raffinaderij B.V. Vondelingenweg 601 Postbus 3000 3196 KK Rotterdam Netherlands Netherlands Cease Manufacture Ethanol, 2-butoxy-, manufacture of, by-products from 310-287-7 161907-77-3 2016 View substance registered dossier
INEOS nv Haven 1053 -- Nieuwe Weg 1 2070 Zwijndrecht Belgium Belgium Cease Manufacture Ethanol, 2-ethoxy-, manufacture of, by-products from 310-288-2 161907-78-4 2019 View substance registered dossier
Shell Nederland Raffinaderij B.V. Vondelingenweg 601 Postbus 3000 3196 KK Rotterdam Netherlands Netherlands Cease Manufacture Ethanol, 2-methoxy-, manufacture of, by-products from 310-289-8 161907-79-5 2016 View substance registered dossier
Shell Nederland Raffinaderij B.V. Vondelingenweg 601 Postbus 3000 3196 KK Rotterdam Netherlands Netherlands Cease Manufacture Ethanol, 2-methoxy-, manufacture of, by-products from, esters with boric acid 310-290-3 161907-80-8 2016 View substance registered dossier
- - - - Ethanone, 1,1'-[1,3-propanediylbis(oxy-4,1-phenylene)]bis[2,2,2-trifluoro-, 1,1'-bis[O-(propylsulfonyl)oxime] 457-550-3 300374-81-6 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Cease Manufacture Ethanone, 1-(1-naphthalenyl)-, oxime, (1E)- 700-765-7 100485-51-6 2019 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture Ethanone, 1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloro- 696-512-2 1378387-81-5 2021 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture Ethanone, 1-[4-(acetyloxy)-3-[(acetyloxy)methyl]phenyl]- 607-317-9 24085-06-1 2016 View substance registered dossier
BASF Italia S.p.A. OR15 Via Marconato 8 20811 Cesano Maderno Italy Italy Cease Manufacture Ethanone, 1-[9-ethyl-6-(2-methylbenzoyl)-9H-carbazol-3-yl]-, 1-(O-acetyloxime) 455-590-6 478556-66-0 2013 View substance registered dossier
BASF Italia S.p.A. Via Marconato 8 20811 Cesano Maderno Italy Italy Cease Manufacture Ethanone, 1-[9-ethyl-6-(2-methylbenzoyl)-9H-carbazol-3-yl]-, 1-(O-acetyloxime) 455-590-6 478556-66-0 2013 View substance registered dossier
Bayer Agriculture bvba Scheldelaan 460 B-2040 Antwerp Belgium Belgium Cease Manufacture Ethanone, 2,2-dichloro-1-[5-(2-furanyl)-2,2-dimethyl-3-oxazolidinyl]- 434-800-1 121776-33-8 2020 View substance registered dossier
Total Lindsey Oil Refinery ltd Eastfield Road DN40 3LW North Lincolnshire United Kingdom United Kingdom No longer Valid Ethers, C5-6-branched alkyl Me 295-322-3 91995-60-7 2021 View substance registered dossier
SARLUX srl S.S. Sulcitana 195 km. 19 09018 Sarroch (CA) Sardinia Italy Italy Cease Manufacture Ethers, C5-6-branched alkyl Me 295-322-3 91995-60-7 2021 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Cease Manufacture Ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]pentanoate 700-226-6 488097-90-1 2017 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture ethyl (2Z)-2-[2-(4-chlorophenyl)hydrazinylidene]-3-(2,6-dichlorophenyl)-3-oxopropanoate 609-702-7 395068-96-9 2018 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture ethyl 2-(2,6-dichlorobenzoyl)-3-oxobutanoate 606-828-4 217458-21-4 2018 View substance registered dossier
SALTIGO GmbH Chempark, Building K 10 51369 Leverkusen Germany Germany Cease Manufacture Ethyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate 700-551-3 179688-27-8 2020 View substance registered dossier
S.A. Ajinomoto OmniChem N.V. Industrial Research Park Fleming 1348 Louvain-la-Neuve Belgium Belgium Cease Manufacture Ethyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate 700-551-3 179688-27-8 2020 View substance registered dossier
- - - - Ethyl 2-hydroxy-3-methylbut-3-enoate 445-780-7 33537-17-6 - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture Ethyl 3,4-dihydroxybenzoate 223-529-0 3943-89-3 2018 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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