Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
tert-butyl 2-hydroxyisobutyrate
252-952-3 36293-63-7 Active Intermediate Joint Intermediate use only 08-11-2017 View substance registered dossier
tert-butyl 2-oxopyrrolidine-1-carboxylate
617-776-7 85909-08-6 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
tert-butyl 3-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-(2-hydroxyethylamino)-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-3-oxo-propyl]indole-1-carboxylate
874-918-2 2461524-68-3 Active Intermediate Individual Intermediate use only 10-10-2022 View substance registered dossier
tert-butyl 3-[(2S)-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-[[2-[[2-[(2S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-methyl-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-3-tert-butoxy-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-3-tert-butoxy-2-[[(2S,3R)-3-tert-butoxy-2-[[(2S)-2-[[(2S,3R)-3-tert-butoxy-2-[[2-[[(2S)-5-tert-butoxy-2-[[2-[[(2S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoyl]amino]-2-methyl-propanoyl]amino]-5-oxo-pentanoyl]amino]acetyl]amino]butanoyl]amino]-3-phenyl-propanoyl]amino]butanoyl]amino]propanoyl]amino]-4-oxo-butanoyl]amino]-3-(4-tert-butoxyphenyl)propanoyl]amino]propanoyl]amino]-3-methyl-pentanoyl]amino]-2-methyl-propanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoyl]amino]-6-(tert-butoxycarbonylamino)hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-oxo-propyl]indole-1-carboxylate
955-944-4 - Active Intermediate Individual Intermediate use only 25-07-2022 View substance registered dossier
Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate
700-004-9 175463-32-8 Active Intermediate Individual Intermediate use only 12-02-2009 View substance registered dossier
tert-butyl 3-oxobutanoate
216-904-5 1694-31-1 Active Intermediate Joint Intermediate use only 08-02-2022 View substance registered dossier
tert-butyl 4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate
941-919-5 1228780-71-9 Active Intermediate Joint Intermediate use only 27-11-2015 View substance registered dossier
tert-butyl 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
942-231-8 1628047-90-4 Active Intermediate Joint Intermediate use only 27-11-2015 View substance registered dossier
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
695-268-4 571188-59-5 Active Intermediate Joint Intermediate use only 22-09-2021 View substance registered dossier
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
695-268-4 571188-59-5 Active Intermediate Individual Intermediate use only 16-07-2013 View substance registered dossier
tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate
801-163-8 571189-16-7 Active Intermediate Joint Intermediate use only 17-12-2021 View substance registered dossier
tert-butyl 4-(aminomethyl)piperidine-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid
870-310-6 2368870-32-8 Active Intermediate Joint Intermediate use only 28-07-2021 View substance registered dossier
tert-butyl 4-(methylsulfonyloxymethyl)piperidine-1-carboxylate
800-659-1 161975-39-9 Active Intermediate Joint Intermediate use only 12-05-2022 View substance registered dossier
tert-butyl 4-[(2-chloropyrimidin-5-yl)oxy]butanoate
872-510-9 945771-55-1 Active Intermediate Joint Intermediate use only 24-01-2023 View substance registered dossier
tert-butyl 4-[(E)-3-(dimethylamino)prop-2-enoyl]piperidine-1-carboxylate
859-135-6 1799799-87-3 Active Intermediate Individual Intermediate use only 27-10-2020 View substance registered dossier
tert-butyl 4-[[(6-amino-5-chloro-pyrimidin-4-yl)amino]methyl]-4-fluoro-piperidine-1-carboxylate
954-331-9 - Active Intermediate Joint Intermediate use only 21-06-2021 View substance registered dossier
tert-butyl 4-bromo-2-fluorobenzoate
810-257-8 889858-12-2 Active Intermediate Joint Intermediate use only 23-11-2015 View substance registered dossier
tert-butyl 4-cyanopiperidine-1-carboxylate
624-826-1 91419-52-2 Active Intermediate Joint Intermediate use only 15-07-2021 View substance registered dossier
tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate hydrochloride
813-852-0 1256584-77-6 Active Intermediate Individual Intermediate use only 28-06-2021 View substance registered dossier
tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate
812-677-7 1256584-75-4 Active Intermediate Individual Intermediate use only 18-11-2021 View substance registered dossier
tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate
836-116-0 480452-36-6 Active Intermediate Joint Intermediate use only 07-06-2022 View substance registered dossier
tert-butyl [(5S,6R)-6-methyl-2-oxo-5-phenylpiperidin-3-yl]carbamate
956-390-6 - Active Intermediate Joint Intermediate use only 28-09-2022 View substance registered dossier
tert-Butyl [(7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro[4.5]dec-7-yl]acetate
920-979-6 - Active Intermediate Joint Intermediate use only 15-02-2013 View substance registered dossier
tert-butyl [(tert-butoxycarbonyl)amino]acetate
696-236-2 111652-20-1 Active Intermediate Individual Intermediate use only 16-11-2015 View substance registered dossier
tert-butyl acetate
208-760-7 540-88-5 Active Intermediate Individual Intermediate use only 14-09-2020 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-butyl 2-hydroxyisobutyrate 252-952-3 36293-63-7 - View substance registered dossier
Chr. Olesen ChemPharm GmbH Innungsstr. 3 21244 Buchholz Germany Germany Active tert-butyl 2-oxopyrrolidine-1-carboxylate 617-776-7 85909-08-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active tert-butyl 2-oxopyrrolidine-1-carboxylate 617-776-7 85909-08-6 2020 View substance registered dossier
[Confidential] - - - tert-butyl 3-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-(2-hydroxyethylamino)-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-3-oxo-propyl]indole-1-carboxylate 874-918-2 2461524-68-3 - View substance registered dossier
[Confidential] - - - tert-butyl 3-[(2S)-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-[[2-[[2-[(2S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-methyl-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-3-tert-butoxy-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-3-tert-butoxy-2-[[(2S,3R)-3-tert-butoxy-2-[[(2S)-2-[[(2S,3R)-3-tert-butoxy-2-[[2-[[(2S)-5-tert-butoxy-2-[[2-[[(2S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoyl]amino]-2-methyl-propanoyl]amino]-5-oxo-pentanoyl]amino]acetyl]amino]butanoyl]amino]-3-phenyl-propanoyl]amino]butanoyl]amino]propanoyl]amino]-4-oxo-butanoyl]amino]-3-(4-tert-butoxyphenyl)propanoyl]amino]propanoyl]amino]-3-methyl-pentanoyl]amino]-2-methyl-propanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoyl]amino]-6-(tert-butoxycarbonylamino)hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-oxo-propyl]indole-1-carboxylate 955-944-4 - - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate 700-004-9 175463-32-8 - View substance registered dossier
Eastman Chemical B.V. Watermanweg 70 3067 GG Rotterdam Netherlands Netherlands Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
SYNTHESIA TECHNOLOGY EUROPE S.L.U C/ Argent, 3 08755 Castellbisbal (Barcelona) Spain Spain Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 2017 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-butyl 3-oxobutanoate 216-904-5 1694-31-1 - View substance registered dossier
[Confidential] - - - tert-butyl 4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate 941-919-5 1228780-71-9 - View substance registered dossier
[Confidential] - - - tert-butyl 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate 942-231-8 1628047-90-4 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 2021 View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 2015; 2017; 2021 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid tert-Butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 801-163-8 571189-16-7 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-(aminomethyl)piperidine-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid 870-310-6 2368870-32-8 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-(methylsulfonyloxymethyl)piperidine-1-carboxylate 800-659-1 161975-39-9 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active tert-butyl 4-[(2-chloropyrimidin-5-yl)oxy]butanoate 872-510-9 945771-55-1 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active tert-butyl 4-[(E)-3-(dimethylamino)prop-2-enoyl]piperidine-1-carboxylate 859-135-6 1799799-87-3 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-[[(6-amino-5-chloro-pyrimidin-4-yl)amino]methyl]-4-fluoro-piperidine-1-carboxylate 954-331-9 - - View substance registered dossier
[Confidential] - - - tert-butyl 4-bromo-2-fluorobenzoate 810-257-8 889858-12-2 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active tert-butyl 4-cyanopiperidine-1-carboxylate 624-826-1 91419-52-2 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl 6-cyano-2-(2-(4-ethyl-3-(4-morpholinopiperidin-1-yl)phenyl)propan-2-yl)-1H-indole-3-carboxylate hydrochloride 813-852-0 1256584-77-6 2021 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate 812-677-7 1256584-75-4 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate 836-116-0 480452-36-6 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-Butyl [(1R,2S,5S)-2-[[2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl]carbamate 836-116-0 480452-36-6 - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active tert-butyl [(5S,6R)-6-methyl-2-oxo-5-phenylpiperidin-3-yl]carbamate 956-390-6 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active tert-Butyl [(7R,9R)-9-(cyanomethyl)-6,10-dioxaspiro[4.5]dec-7-yl]acetate 920-979-6 - 2013 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-butyl [(tert-butoxycarbonyl)amino]acetate 696-236-2 111652-20-1 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active tert-butyl acetate 208-760-7 540-88-5 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.