Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
TERT-AMYL OXALATE
437-440-1 - No longer Valid NONS Individual No longer valid 19-02-2009 View substance registered dossier
tert-butyl ((1S)-2-((1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl)-1-(3-hydroxyadamantan-1-yl)-2-oxoethyl)carbamate
687-691-8 709031-43-6 Active Full Individual ≥ 1 to < 10 tonnes 13-09-2012 View substance registered dossier
tert-Butyl ((1S)-2-hydroxy-1-methylethyl)carbamate
807-439-4 79069-13-9 Active Intermediate Individual Intermediate use only 05-12-2017 View substance registered dossier
tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
609-213-9 361440-67-7 Active Intermediate Individual Intermediate use only 20-03-2017 View substance registered dossier
tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate
810-524-9 937046-96-3 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate
810-524-9 937046-96-3 Active Intermediate Individual Intermediate use only 26-03-2019 View substance registered dossier
tert-butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate
615-204-0 709031-38-9 Active Intermediate Individual Intermediate use only 21-03-2017 View substance registered dossier
tert-butyl (2S)-2-{5-[4-(4-{2-[(2S)-1-[(tert-butoxy)carbonyl]pyrrolidin-2-yl]-1H-imidazol-5-yl}phenyl)phenyl]-1H-imidazol-2-yl}pyrrolidine-1-carboxylate
941-432-8 - Active Intermediate Individual Intermediate use only 26-09-2014 View substance registered dossier
tert-butyl (2S,4S)-2-[4-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate
807-100-0 1378391-45-7 Active Intermediate Individual Intermediate use only 28-09-2016 View substance registered dossier
tert-butyl (3R)-3-{3-iodo-4-[(triphenylphosphanylidene)amino]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}piperidine-1-carboxylate
953-572-7 - Active Intermediate Individual Intermediate use only 06-07-2022 View substance registered dossier
tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
626-373-5 143900-44-1 Active Intermediate Individual Intermediate use only 06-10-2021 View substance registered dossier
tert-butyl (3S,5S)-3-isopropyl-5-((2S,4S)-tetrahydro-4-isopropyl-5-oxo-furan-2-yl)-2-oxo-pyrrolidine-carboxylate
472-680-0 - No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate
810-525-4 937047-04-6 Active Intermediate Individual Intermediate use only 23-04-2019 View substance registered dossier
tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate
810-525-4 937047-04-6 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
3-BMC
407-620-4 33610-13-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate
810-523-3 937046-95-2 Active Intermediate Individual Intermediate use only 27-02-2018 View substance registered dossier
tert-butyl 1H-pyrrol-1-ylcarbamate
810-523-3 937046-95-2 Cease Manufacture Intermediate Individual Cease manufacture 24-08-2015 View substance registered dossier
tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate
606-022-2 184177-88-6 Active Intermediate Individual Intermediate use only 30-05-2018 View substance registered dossier
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 29-09-2010 View substance registered dossier
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 04-03-2011 View substance registered dossier
tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate
700-258-0 125971-95-1 Active Intermediate Individual Intermediate use only 27-10-2010 View substance registered dossier
tert-butyl 3-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-(2-hydroxyethylamino)-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-3-oxo-propyl]indole-1-carboxylate
874-918-2 2461524-68-3 Active Intermediate Individual Intermediate use only 10-10-2022 View substance registered dossier
tert-butyl 3-[(2S)-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-[[2-[[2-[(2S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-methyl-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-3-tert-butoxy-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-3-tert-butoxy-2-[[(2S,3R)-3-tert-butoxy-2-[[(2S)-2-[[(2S,3R)-3-tert-butoxy-2-[[2-[[(2S)-5-tert-butoxy-2-[[2-[[(2S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoyl]amino]-2-methyl-propanoyl]amino]-5-oxo-pentanoyl]amino]acetyl]amino]butanoyl]amino]-3-phenyl-propanoyl]amino]butanoyl]amino]propanoyl]amino]-4-oxo-butanoyl]amino]-3-(4-tert-butoxyphenyl)propanoyl]amino]propanoyl]amino]-3-methyl-pentanoyl]amino]-2-methyl-propanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoyl]amino]-6-(tert-butoxycarbonylamino)hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-oxo-propyl]indole-1-carboxylate
955-944-4 - Active Intermediate Individual Intermediate use only 25-07-2022 View substance registered dossier
Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate
700-004-9 175463-32-8 Active Intermediate Individual Intermediate use only 12-02-2009 View substance registered dossier
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
695-268-4 571188-59-5 Active Full Individual ≥ 10 to < 100 tonnes 24-07-2018 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
- - - - TERT-AMYL OXALATE 437-440-1 - - View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active tert-butyl ((1S)-2-((1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hex-2-yl)-1-(3-hydroxyadamantan-1-yl)-2-oxoethyl)carbamate 687-691-8 709031-43-6 - View substance registered dossier
Fermion Oy Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland Finland Active tert-Butyl ((1S)-2-hydroxy-1-methylethyl)carbamate 807-439-4 79069-13-9 - View substance registered dossier
[Confidential] - - - tert-butyl (1S,3S,5S)-3-carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate 609-213-9 361440-67-7 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate 810-524-9 937046-96-3 2016 View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl (2-cyano-1H-pyrrol-1-yl)carbamate 810-524-9 937046-96-3 - View substance registered dossier
[Confidential] - - - tert-butyl (2S)-2-carbamoyl-2,3-dihydropyrrole-1-carboxylate 615-204-0 709031-38-9 - View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active tert-butyl (2S)-2-{5-[4-(4-{2-[(2S)-1-[(tert-butoxy)carbonyl]pyrrolidin-2-yl]-1H-imidazol-5-yl}phenyl)phenyl]-1H-imidazol-2-yl}pyrrolidine-1-carboxylate 941-432-8 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active tert-butyl (2S,4S)-2-[4-(2-{(2S,5S)-1-[N-(methoxycarbonyl)-L-valyl]-5-methylpyrrolidin-2-yl}-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl]-4-(methoxymethyl)pyrrolidine-1-carboxylate 807-100-0 1378391-45-7 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-butyl (3R)-3-{3-iodo-4-[(triphenylphosphanylidene)amino]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}piperidine-1-carboxylate 953-572-7 - - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate 626-373-5 143900-44-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - No longer Valid tert-butyl (3S,5S)-3-isopropyl-5-((2S,4S)-tetrahydro-4-isopropyl-5-oxo-furan-2-yl)-2-oxo-pyrrolidine-carboxylate 472-680-0 - 2022 View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate 810-525-4 937047-04-6 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl (4-bromo-2-cyano-1H-pyrrol-1-yl)carbamate 810-525-4 937047-04-6 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active tert-butyl (5S,6R,7R)-3-bromomethyl-5,8-dioxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 407-620-4 33610-13-8 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Active tert-butyl 1H-pyrrol-1-ylcarbamate 810-523-3 937046-95-2 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture tert-butyl 1H-pyrrol-1-ylcarbamate 810-523-3 937046-95-2 2016 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active tert-butyl 2-[(2S,3S)-2-(benzyloxy)pentan-3-yl]hydrazinecarboxylate 606-022-2 184177-88-6 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 - View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 2011 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 700-258-0 125971-95-1 2008; 2010 View substance registered dossier
[Confidential] - - - tert-butyl 3-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-(2-hydroxyethylamino)-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-3-oxo-propyl]indole-1-carboxylate 874-918-2 2461524-68-3 - View substance registered dossier
[Confidential] - - - tert-butyl 3-[(2S)-3-[[(1S)-1-[[(1S,2S)-1-[[(1S)-2-[[2-[[2-[(2S)-2-[[(1S)-2-[[(1S)-2-[[2-[[(1S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[[(1S)-2-amino-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-methyl-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]amino]-1-(tert-butoxymethyl)-2-oxo-ethyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-3-tert-butoxy-2-[[(2S)-2-[[(2S)-4-tert-butoxy-2-[[(2S)-3-tert-butoxy-2-[[(2S,3R)-3-tert-butoxy-2-[[(2S)-2-[[(2S,3R)-3-tert-butoxy-2-[[2-[[(2S)-5-tert-butoxy-2-[[2-[[(2S)-2-(tert-butoxycarbonylamino)-3-(4-tert-butoxyphenyl)propanoyl]amino]-2-methyl-propanoyl]amino]-5-oxo-pentanoyl]amino]acetyl]amino]butanoyl]amino]-3-phenyl-propanoyl]amino]butanoyl]amino]propanoyl]amino]-4-oxo-butanoyl]amino]-3-(4-tert-butoxyphenyl)propanoyl]amino]propanoyl]amino]-3-methyl-pentanoyl]amino]-2-methyl-propanoyl]amino]-4-methyl-pentanoyl]amino]-4-oxo-butanoyl]amino]-6-(tert-butoxycarbonylamino)hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoyl]amino]propanoyl]amino]-3-phenyl-propanoyl]amino]-3-methyl-butanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]-3-oxo-propyl]indole-1-carboxylate 955-944-4 - - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active Tert-butyl 3-Cyano-4-oxo-pyrrolidine-1-carboxylate 700-004-9 175463-32-8 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate 695-268-4 571188-59-5 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.