Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
Ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate
CA 875 B
414-450-4 88805-65-6 Active Intermediate Individual Intermediate use only 14-11-2012 View substance registered dossier
Ethyl 3-oxo-(2,3,4,5-tetrafluorophenyl)propanoate
700-167-6 94695-50-8 Active Intermediate Individual Intermediate use only 26-01-2011 View substance registered dossier
ethyl 3-oxo-4-(2-(tritylamino)ethoxy)butanoate
619-692-6 156366-26-6 Active Intermediate Individual Intermediate use only 14-07-2008 View substance registered dossier
Ethyl 3-oxohexanoate
221-835-9 3249-68-1 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
Ethyl 4,4,4-trifluoroacetoacetate
206-750-7 372-31-6 Active Intermediate Joint Intermediate use only 29-10-2019 View substance registered dossier
Ethyl 4,4-dimethoxy-3-methyl-2-butenoate
280-901-5 83803-81-0 Active Intermediate Joint Intermediate use only 04-07-2016 View substance registered dossier
Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate
605-866-9 179688-26-7 Cease Manufacture Intermediate Individual Cease manufacture 12-11-2012 View substance registered dossier
Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate
604-436-8 144690-33-5 Active Intermediate Joint Intermediate use only 04-01-2021 View substance registered dossier
Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate
604-434-7 144689-93-0 Active Intermediate Joint Intermediate use only 06-01-2022 View substance registered dossier
Ethyl 4-(bromomethyl)-2-[(2,6-difluorophenyl)methyl-ethoxycarbonylamino]-5-(4-nitrophenyl)thiophene-3-carboxylate
840-149-6 308831-95-0 Active Intermediate Joint Intermediate use only 28-01-2021 View substance registered dossier
Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate
217-412-3 1838-39-7 Active Intermediate Joint Intermediate use only 01-02-2022 View substance registered dossier
Ethyl 4-[(2-aminoacetyl)amino]-3-methoxy benzoate, HCl
810-628-4 1606132-23-3 Active Intermediate Individual Intermediate use only 03-06-2016 View substance registered dossier
Ethyl 4-[(3-chloro-4-methoxy-phenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylate
809-849-9 330785-83-6 Active Intermediate Joint Intermediate use only 24-03-2015 View substance registered dossier
Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate
801-713-7 330785-81-4 Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
ethyl 4-[(3-ethoxy-3-oxopropyl)(methyl)amino]butanoate
600-917-1 109386-70-1 Active Intermediate Joint Intermediate use only 27-11-2015 View substance registered dossier
Ethyl 4-bromobutyrate
221-005-6 2969-81-5 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
227-619-0 5909-24-0 Active Intermediate Joint Intermediate use only 04-05-2018 View substance registered dossier
Ethyl 4-chloroacetoacetate
211-317-0 638-07-3 Active Intermediate Joint Intermediate use only 24-11-2017 View substance registered dossier
Ethyl 4-hydroxy-2-(methylsulfanyl)-5-pyrimidinecarboxylate
633-406-7 53554-29-3 Active Intermediate Joint Intermediate use only 13-05-2020 View substance registered dossier
Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
246-403-7 24683-26-9 Active Intermediate Individual Intermediate use only 09-03-2012 View substance registered dossier
Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
246-403-7 24683-26-9 Active Intermediate Joint Intermediate use only 01-04-2022 View substance registered dossier
Ethyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
607-417-2 24683-21-4 Active Intermediate Joint Intermediate use only 31-03-2022 View substance registered dossier
Ethyl 4-hydroxypiperidine-1-carboxylate
265-636-5 65214-82-6 Active Intermediate Joint Intermediate use only 09-07-2021 View substance registered dossier
Ethyl 4-methyloxazole-5-carboxylate
243-848-9 20485-39-6 Active Intermediate Joint Intermediate use only 06-09-2019 View substance registered dossier
ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
695-104-1 52980-28-6 Active Intermediate Joint Intermediate use only 23-09-2021 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
ESIM Chemicals GmbH St.-Peter-Strasse 25 4020 Linz Austria Austria Active Ethyl 3-hydroxy-5-oxo-3-cyclohexene-1-carboxylate 414-450-4 88805-65-6 2012 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active Ethyl 3-oxo-(2,3,4,5-tetrafluorophenyl)propanoate 700-167-6 94695-50-8 2009; 2011 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active ethyl 3-oxo-4-(2-(tritylamino)ethoxy)butanoate 619-692-6 156366-26-6 2008 View substance registered dossier
HERBRAND PharmaChemicals GmbH Brambachstraße 31 77723 Gengenbach B-W Germany Germany Active Ethyl 3-oxohexanoate 221-835-9 3249-68-1 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl 3-oxohexanoate 221-835-9 3249-68-1 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 - View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 2017 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Ethyl 4,4-dimethoxy-3-methyl-2-butenoate 280-901-5 83803-81-0 - View substance registered dossier
S.A. Ajinomoto OmniChem N.V. Industrial Research Park Fleming 1348 Louvain-la-Neuve Belgium Belgium Cease Manufacture Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 605-866-9 179688-26-7 2020 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate 604-436-8 144690-33-5 2021 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate 604-434-7 144689-93-0 - View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate 604-434-7 144689-93-0 2022 View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active Ethyl 4-(bromomethyl)-2-[(2,6-difluorophenyl)methyl-ethoxycarbonylamino]-5-(4-nitrophenyl)thiophene-3-carboxylate 840-149-6 308831-95-0 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active Ethyl 4-(bromomethyl)-2-[(2,6-difluorophenyl)methyl-ethoxycarbonylamino]-5-(4-nitrophenyl)thiophene-3-carboxylate 840-149-6 308831-95-0 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate 217-412-3 1838-39-7 2022 View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate 217-412-3 1838-39-7 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active Ethyl 4-(ethoxycarbonyl)piperidine-1-acetate 217-412-3 1838-39-7 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active Ethyl 4-[(2-aminoacetyl)amino]-3-methoxy benzoate, HCl 810-628-4 1606132-23-3 - View substance registered dossier
[Confidential] - - - Ethyl 4-[(3-chloro-4-methoxy-phenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylate 809-849-9 330785-83-6 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active Ethyl 4-[(3-chloro-4-methoxybenzyl)amino]-2-(methylsulfanyl)pyrimidine-5-carboxylate 801-713-7 330785-81-4 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active ethyl 4-[(3-ethoxy-3-oxopropyl)(methyl)amino]butanoate 600-917-1 109386-70-1 - View substance registered dossier
PALCHEM Rue du Transvaal BP22 62143 ANGRES France France Active Ethyl 4-bromobutyrate 221-005-6 2969-81-5 - View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Active Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 227-619-0 5909-24-0 2018 View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 227-619-0 5909-24-0 - View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active Ethyl 4-chloroacetoacetate 211-317-0 638-07-3 - View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Active Ethyl 4-hydroxy-2-(methylsulfanyl)-5-pyrimidinecarboxylate 633-406-7 53554-29-3 2020 View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A. Viale del Ghisallo, 20 20151 Milano Italy Italy Active Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 246-403-7 24683-26-9 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 246-403-7 24683-26-9 2017 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 246-403-7 24683-26-9 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 246-403-7 24683-26-9 2017; 2022 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 246-403-7 24683-26-9 2017 View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Ethyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide 607-417-2 24683-21-4 2022 View substance registered dossier
Interpharma Praha Komoranska 955 14300 Prague Czech Republic Czech Republic Active Ethyl 4-hydroxypiperidine-1-carboxylate 265-636-5 65214-82-6 - View substance registered dossier
[Confidential] - - - Ethyl 4-methyloxazole-5-carboxylate 243-848-9 20485-39-6 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active ethyl 4-oxo-1,4-dihydroquinoline-3-carboxylate 695-104-1 52980-28-6 2012; 2015; 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.