Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

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Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Showing 20,001 - 20,200 of 26,865 results.
Name
EC / List no.
CAS no.
Registration Status
Registration type
Submission type
Total tonnage band
Last Updated
Details
(2E,4E)-2-methyl-5-phenyl-penta-2,4-dienal
919-772-3 - Active Intermediate Individual Intermediate use only 11-12-2015 View substance registered dossier
(2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
951-764-5 - Active Intermediate Individual Intermediate use only 15-01-2020 View substance registered dossier
(2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt
944-007-5 - Active Intermediate Joint Intermediate use only 13-12-2016 View substance registered dossier
(2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1)
947-841-8 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate
UK-103,449-BV
427-100-0 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1)
920-610-9 - Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
(2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1)
947-840-2 - Active Intermediate Individual Intermediate use only 16-05-2018 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - Active Intermediate Joint Intermediate use only 04-10-2018 View substance registered dossier
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate
927-721-1 - Active Intermediate Joint Intermediate use only 19-06-2020 View substance registered dossier
(2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride
928-729-8 - Active Intermediate Joint Intermediate use only 24-04-2013 View substance registered dossier
(2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate
917-473-2 - Active Intermediate Joint Intermediate use only 16-04-2013 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Full Joint ≥ 10 to < 100 tonnes 16-05-2017 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Full Joint ≥ 10 tonnes 15-02-2012 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Intermediate Joint Intermediate use only 19-12-2016 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Joint Intermediate use only 26-02-2020 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Joint Intermediate use only 28-01-2019 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Cease Manufacture Intermediate Individual Cease manufacture 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid
954-943-6 - Active Intermediate Individual Intermediate use only 10-10-2022 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1)
- - Active Intermediate Joint Intermediate use only 04-06-2021 View substance registered dossier
(2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone
477-290-4 - Active NONS Joint Tonnage data confidential 01-03-2013 View substance registered dossier
(2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
475-290-9 - Active Full Joint ≥ 1 to < 10 tonnes 15-11-2022 View substance registered dossier
(2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
475-290-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid
949-609-1 - Active Intermediate Joint Intermediate use only 29-04-2022 View substance registered dossier
(2S, 4R)-1-((S)-2-(tert-butoxycarbonylamino)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylic acid compound with tetrahydrofuran
941-817-0 - Active Intermediate Individual Intermediate use only 10-02-2015 View substance registered dossier
(2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1)
947-432-4 - Active Intermediate Joint Intermediate use only 04-09-2020 View substance registered dossier
(2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2)
954-871-5 - Active Intermediate Individual Intermediate use only 19-08-2021 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - No longer Valid Intermediate Individual No longer valid 19-10-2012 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - Cease Manufacture Intermediate Individual Cease manufacture 05-11-2012 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - No longer Valid Intermediate Joint No longer valid 04-09-2012 View substance registered dossier
(2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate
942-044-1 - Active Intermediate Joint Intermediate use only 27-02-2017 View substance registered dossier
(2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate
938-481-2 - Active Intermediate Joint Intermediate use only 31-10-2018 View substance registered dossier
(2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester
411-020-8 - Active Intermediate Joint Intermediate use only 09-12-2013 View substance registered dossier
(2S,4R)-1-hexadecanoyl-4-hydroxy-pyrrolidine-2-carboxylic acid
944-347-4 - Active Intermediate Joint Intermediate use only 13-03-2017 View substance registered dossier
(2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid
444-810-6 - Active Full Joint ≥ 10 to < 100 tonnes 11-05-2021 View substance registered dossier
(3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane)
951-684-0 - Active Intermediate Joint Intermediate use only 26-02-2021 View substance registered dossier
(3-(4-((((3β)-cholest-5-en-yl)oxy)carbonyl)phenoxy)propylmethyl-co-3-(4-((2-methyl-2-propenoyloxy)phenyloxy)carbonyl)-phenoxy)propylmethyl)cyclotetrasiloxane)
LC-OLIGOMER
454-660-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3-(Formylamino)propyl)dimethylammonioacetate
480-680-7 - Active Full Joint ≥ 100 to < 1 000 tonnes 22-10-2020 View substance registered dossier
(3-Chloro-4-fluoro-phenyl)-{6-nitro-7-[(S)-(tetrahydro-furan-3-yl)oxy]-quinazolin-4-yl}-amine
925-395-5 - Active Intermediate Joint Intermediate use only 24-03-2021 View substance registered dossier
(3-chloropyridin-2-yl)hydrazine
474-260-2 - Active Intermediate Joint Intermediate use only 24-09-2020 View substance registered dossier
(3-fluoro-4'-pentyl[1,1'-biphenyl]-4-yl)-boronic acid
936-618-0 - Active Full Joint ≥ 0 to < 10 tonnes 12-02-2019 View substance registered dossier
(3-methoxy-2-methylpropyl)benzene
430-150-6 - Active Full Joint ≥ 1 to < 10 tonnes 22-12-2016 View substance registered dossier
(3-methoxy-2-methylpropyl)benzene
430-150-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE
443-930-6 - Active Full Joint ≥ 10 to < 100 tonnes 03-05-2018 View substance registered dossier
(3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE
443-930-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)
931-336-4 - Cease Manufacture Intermediate Individual Cease manufacture 13-09-2012 View substance registered dossier
(3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate
701-382-8 - Active Intermediate Joint Intermediate use only 09-04-2021 View substance registered dossier
(3R)-4[(4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one
954-618-9 - Active Intermediate Individual Intermediate use only 21-03-2022 View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
918-279-0 - Active Intermediate Joint Intermediate use only 26-04-2017 View substance registered dossier
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
942-823-6 - Cease Manufacture Intermediate Individual Cease manufacture 03-11-2015 View substance registered dossier
(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone
429-980-1 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate
950-060-5 - Active Intermediate Joint Intermediate use only 15-01-2020 View substance registered dossier
(3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate
954-955-1 - Active Intermediate Joint Intermediate use only 27-09-2021 View substance registered dossier
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine
929-011-7 - Active Intermediate Joint Intermediate use only 20-04-2018 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 16-05-2018 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 12-07-2013 View substance registered dossier
(3S,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one 4-methylbenzoate
939-788-4 - Active Intermediate Joint Intermediate use only 15-05-2023 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active Full Joint ≥ 0 to < 10 tonnes 16-04-2018 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one
427-070-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-6) PEPTIDE
427-550-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-methoxybiphenyl-3-yl)hydrazine hydrochloride
924-885-6 - Active Intermediate Joint Intermediate use only 22-10-2012 View substance registered dossier
(4-Methoxyphenyl)diphenylsulfoniumnonaflate
435-570-3 - Active NONS Joint Tonnage data confidential 24-06-2009 View substance registered dossier
(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
ENOL SULFOXIDE ESTER
411-820-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate
453-050-4 - Active NONS Individual Tonnage data confidential 04-02-2011 View substance registered dossier
(4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)
700-867-1 - Active Full Joint ≥ 1 to < 10 tonnes 11-06-2020 View substance registered dossier
(4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene
700-678-4 - Active Full Individual ≥ 100 to < 1 000 tonnes 05-05-2020 View substance registered dossier
(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one
939-401-9 - Active Full Joint ≥ 100 to < 1 000 tonnes 09-05-2023 View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine
926-346-0 - Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
(4R)-4-methyl-1,3-dioxolan-2-one
(R)-1,2-PROPYLENE CARBONATE
437-320-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Active Full Joint ≥ 1 to < 10 tonnes 18-08-2020 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate)
956-466-9 - Active Intermediate Joint Intermediate use only 07-10-2022 View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate
947-346-7 - Active Intermediate Individual Intermediate use only 03-01-2023 View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)
940-053-5 - Active Intermediate Joint Intermediate use only 19-01-2017 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate
947-931-7 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)
925-915-0 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
HYDROXYECTOIN
442-870-8 - Cease Manufacture NONS Joint Cease manufacture 10-11-2008 View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide
947-800-4 - Active Intermediate Joint Intermediate use only 21-06-2018 View substance registered dossier
(4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid
MDL 28,690
443-440-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(5-chloro-2-methoxyphenyl)boronic acid
923-256-3 - Active Intermediate Individual Intermediate use only 27-04-2018 View substance registered dossier
(5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine
700-700-2 - Active Intermediate Joint Intermediate use only 30-09-2022 View substance registered dossier
(5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione
700-726-4 - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate
938-716-9 - No longer Valid Intermediate Individual No longer valid 04-02-2013 View substance registered dossier
(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid
921-925-4 - Active Intermediate Joint Intermediate use only 14-02-2022 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-11-2014 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Active Intermediate Individual Intermediate use only 18-12-2013 View substance registered dossier
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt
439-350-8 - Cease Manufacture NONS Individual Cease manufacture 22-12-2010 View substance registered dossier
(6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine
921-415-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine
918-453-6 - Active Intermediate Individual Intermediate use only 31-08-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine
917-585-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate
949-377-1 - Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active Intermediate Joint Intermediate use only 13-11-2017 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
435-680-1 - Cease Manufacture Full Individual Cease manufacture 17-05-2018 View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
434-320-0 - Cease Manufacture NONS Joint Cease manufacture 15-11-2012 View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
434-320-0 - Active Intermediate Joint Intermediate use only 08-10-2021 View substance registered dossier
(6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione
695-945-4 - Active Intermediate Joint Intermediate use only 23-06-2022 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active Full Individual ≥ 1 to < 10 tonnes 08-06-2010 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
943-624-7 - Active Intermediate Joint Intermediate use only 01-03-2022 View substance registered dossier
(7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one
955-019-5 - Active Intermediate Joint Intermediate use only 22-10-2021 View substance registered dossier
(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)
926-987-6 - Active Intermediate Joint Intermediate use only 13-12-2021 View substance registered dossier
(8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[25.2.2.0³,⁸]hentriacont-17-en-6-yl]methyl acetate
941-809-7 - Active Full Joint ≥ 10 to < 100 tonnes 18-05-2022 View substance registered dossier
(alpha-cyanobenzyl)malonic acid diethyl ester
922-463-6 - Active Intermediate Joint Intermediate use only 17-02-2017 View substance registered dossier
(aminoalkyl) hydrogen thiosulfate
- - Active Full Joint ≥ 1 to < 10 tonnes 05-01-2021 View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate
442-520-4 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate
442-520-4 - Active Full Joint ≥ 1 tonnes 12-02-2020 View substance registered dossier
(C14-C30-alkyl)phenyl-3-tolyliodonium trifluoromethansulfonate
DOW CORNING(R) 2-7103 CATALYST
424-410-8 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(C14/C16/C18) n-alkyl (of non animal origin)benzyl dimethyl ammonium chloride compound with bentonite
TIXOGEL VZ-V
436-020-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(C16 or C18-n-alkyl)(C16 or C18-n-alkyl)ammonium 2-((C16 or C18-n-alkyl)(C16 or C18-n-alkyl)carbamoyl)benzenesulfonate
OA 8523
402-460-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine
700-519-9 - Active Intermediate Joint Intermediate use only 13-01-2020 View substance registered dossier
(D)-2-BROM-3-PHENYLPROPIONSÄURE-ETHYLENDIAMINSALZ
447-890-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(D)-p-hydroxyphenylglycine-2-hydroxyethylester, hydrochloride
433-310-3 - Active NONS Joint Tonnage data confidential 04-02-2011 View substance registered dossier
(Dimethoxy(methyl)silyl)methyl 2-methacrylate
479-600-3 - Active Full Joint ≥ 1 tonnes 02-12-2016 View substance registered dossier
(E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime
456-110-8 - Active Intermediate Joint Intermediate use only 06-04-2022 View substance registered dossier
(E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate
944-280-0 - Active Full Joint ≥ 10 to < 100 tonnes 18-03-2020 View substance registered dossier
(E)-2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-ylmethylene)-5,6-dimethoxy-indan-1-one hydrochloride
940-983-1 - Active Intermediate Individual Intermediate use only 03-12-2014 View substance registered dossier
(E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenyl-amino)-7-((S)-(tetrahydrofuran-3-yl)oxy)-quinazoline-6-yl]-amide
923-981-5 - Active Intermediate Joint Intermediate use only 17-02-2023 View substance registered dossier
(E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT)
475-900-3 - Active Intermediate Individual Intermediate use only 10-12-2019 View substance registered dossier
(E)-ethyl 4-(dimethylamino)but-2-enoate maleate
941-772-7 - Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
(E)-Ethyl 4-oxo-but-2-enoate
438-470-8 - Active NONS Joint Tonnage data confidential 09-06-2022 View substance registered dossier
(E)-Ethyl 4-oxo-but-2-enoate
438-470-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(E)-N'-hydroxy-N-(4-hydroxypyrid-2-yl)formimidamide
952-647-1 - Active Intermediate Joint Intermediate use only 01-07-2020 View substance registered dossier
(E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine
449-170-1 - Active NONS Joint Tonnage data confidential 24-09-2010 View substance registered dossier
(E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine
449-170-1 - Active NONS Joint Tonnage data confidential 12-06-2017 View substance registered dossier
(E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide
- - Active Intermediate Individual Intermediate use only 08-11-2016 View substance registered dossier
(ethyl-1,2-ethanediyl)]-2-[[[(2-hydroxyethyl)methylamino]acetyl]propyl]ω-(nonylphenoxy)poly[oxy(methyl-1,2-ethanediyl)
TFA-4713
418-960-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride
CHLORHYDRATE DE CARCININE
415-470-6 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate)
950-860-4 - Active Intermediate Joint Intermediate use only 04-05-2021 View substance registered dossier
(N-phenylcarbamimidoyl)ammonium carbonate hydrate
485-350-6 - Active Intermediate Individual Intermediate use only 19-08-2019 View substance registered dossier
(N-phenylcarbamimidoyl)ammonium carbonate hydrate
485-350-6 - Active Intermediate Individual Intermediate use only 21-12-2018 View substance registered dossier
(n-{(1s,3s)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide hydrochloride)
952-248-2 - Active Intermediate Joint Intermediate use only 18-12-2020 View substance registered dossier
(NZ)-N-[1-(2,4-dichlorophenyl)-2-imidazol-1-ylethylidene]hydroxylamine
917-661-4 - Active Intermediate Joint Intermediate use only 14-02-2017 View substance registered dossier
(R)-1-(1H-benzo[d]imidazol-4-yl)propan-2-amine dihydrochloride
956-605-3 - Active Intermediate Joint Intermediate use only 27-10-2022 View substance registered dossier
(R)-1-(1H-indazol-4-yl)-N-(2,2,2-trifluoroethyl)propan-2-amine 10-camphorsulfonic acid salt
956-342-4 - Active Intermediate Joint Intermediate use only 01-09-2022 View substance registered dossier
(R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid
941-846-9 - Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
(R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride
444-320-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol
929-946-0 - Active Intermediate Joint Intermediate use only 05-12-2017 View substance registered dossier
(R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate
929-947-6 - Active Intermediate Joint Intermediate use only 31-10-2017 View substance registered dossier
(R)-2-acetamido-3-naphthyl-2-yl-propionic acid
(R)-2-ACETAMIDO-3-NAPHTHYLEN-2-YL-PROPIONIC ACID
440-450-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate
942-402-7 - Active Intermediate Joint Intermediate use only 24-09-2021 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(4-CHLOROPHENYL)-PROPIONIC ACID
438-070-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid
(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(PYRIDIN-3-YL) PROPIONIC ACID
441-200-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole
921-685-0 - Active Intermediate Joint Intermediate use only 05-08-2022 View substance registered dossier
(R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate
949-784-4 - Active Intermediate Individual Intermediate use only 25-03-2019 View substance registered dossier
(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
920-209-9 - Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
419-800-1 - Active Full Joint ≥ 0 to < 10 tonnes 05-12-2019 View substance registered dossier
(R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide
419-800-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate
430-790-6 - Active Intermediate Joint Intermediate use only 05-05-2015 View substance registered dossier
(R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate
430-790-6 - Active Intermediate Joint Intermediate use only 01-05-2018 View substance registered dossier
(Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated
926-000-9 - Active Full Individual ≥ 100 to < 1 000 tonnes 11-07-2022 View substance registered dossier
(RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine
434-800-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine
434-800-1 - Cease Manufacture Full Individual Cease manufacture 05-11-2020 View substance registered dossier
(S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt
918-890-2 - Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - No longer Valid Intermediate Individual No longer valid 22-09-2011 View substance registered dossier
(S)-(-)-tetrahydro-2-furoic acid
433-770-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-1,2,4-butanetriyltrimethanesulfonate
UK-164,608
433-850-1 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole Tartrat Trihydrate
928-472-1 - Active Intermediate Joint Intermediate use only 26-10-2021 View substance registered dossier
(S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride
942-180-1 - Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
(S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid
951-381-3 - Active Intermediate Individual Intermediate use only 02-07-2021 View substance registered dossier
(S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid
- - Active Intermediate Joint Intermediate use only 09-10-2013 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 - Active Intermediate Individual Intermediate use only 07-02-2022 View substance registered dossier
(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid
FMOC AMINO ACID 4
439-640-4 - Active NONS Joint Tonnage data confidential 17-08-2010 View substance registered dossier
(S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
ECTOIN
431-910-1 - Active Full Joint ≥ 1 tonnes 19-08-2022 View substance registered dossier
(S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
ECTOIN
431-910-1 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(S)-3-[1-(Dimethylamino)ethyl]-phenol
478-670-2 - Active Intermediate Joint Intermediate use only 11-10-2010 View substance registered dossier
(S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one
480-320-9 - Active Full Joint ≥ 0 tonnes 06-02-2009 View substance registered dossier
(S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one
480-320-9 - Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(S)-3-Hydroxytetrahydrofurane
425-090-2 - Cease Manufacture Intermediate Joint Cease manufacture 10-05-2010 View substance registered dossier
(S)-3-Hydroxytetrahydrofurane
425-090-2 - No longer Valid NONS Joint No longer valid 10-11-2008 View substance registered dossier
(S)-3-Hydroxytetrahydrofurane
425-090-2 - Active Intermediate Joint Intermediate use only 14-02-2020 View substance registered dossier
(S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid
L-GLUTAMYL-HISTAMINE
421-900-3 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene
LACTOFTALURO
410-940-7 - Active Intermediate Joint Intermediate use only 20-05-2022 View substance registered dossier
(S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride
948-271-2 - Active Intermediate Joint Intermediate use only 09-07-2018 View substance registered dossier
(S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl) 5-tert-butyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate
941-125-9 - Cease Manufacture Intermediate Joint Cease manufacture 09-06-2015 View substance registered dossier
(S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether
471-940-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Active Intermediate Joint Intermediate use only 08-07-2015 View substance registered dossier
(S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle
439-220-0 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active Intermediate Individual Intermediate use only 19-06-2018 View substance registered dossier
(S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate
445-820-3 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(S)-ethyl-3-amino-3-phenylpropanoate hemi (2S,3S)-2,3-dihydroxysuccinate
955-403-2 - Active Intermediate Joint Intermediate use only 14-10-2022 View substance registered dossier
(S)-N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-amine
942-077-1 - Active Intermediate Joint Intermediate use only 18-01-2018 View substance registered dossier
(S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate
924-425-4 - Active Intermediate Joint Intermediate use only 07-08-2020 View substance registered dossier
(S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate
942-159-7 - Cease Manufacture Intermediate Individual Cease manufacture 20-07-2015 View substance registered dossier
(S)-tert.-Butyl-[2-(aminoethoxy)-[1,2]oxaborolan-4-yl]acetate
942-682-0 - Active Intermediate Individual Intermediate use only 05-03-2018 View substance registered dossier
(S)Ammonium-(2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
926-381-1 - Active Intermediate Joint Intermediate use only 23-03-2018 View substance registered dossier
(trans(trans))-4'-but-3-enyl-4-(4-methylphenyl)-bicyclohexyl
1-(TRANS,TRANS-4'-(3-BUTENYL)-BICYCLOHEXYL-4-YL)-4-METHYLBEN
429-580-7 - Active Full Joint ≥ 0 to < 10 tonnes 06-02-2020 View substance registered dossier
(trans(trans))-4'-vinyl-4-(4-methylphenyl)bicyclohexyl
LICRISTAL CCP-V-1
439-730-3 - Active Full Joint ≥ 0 to < 10 tonnes 02-12-2019 View substance registered dossier
(Trimethoxysilyl)methyl 2-methacrylate
454-220-0 - Active Full Joint ≥ 10 tonnes 16-11-2016 View substance registered dossier
(TRIMETHYLENEDINITRILO)TETRAKISACETONITRILE
429-330-7 - Cease Manufacture Intermediate Individual Cease manufacture 03-02-2012 View substance registered dossier
(trimethylvinylsilyl)hexafluoroacetylacetonato copper I
CUPRA SELECT
435-140-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(xylenes and 4-ethylbenzene)sulfonic acids
701-247-3 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 06-03-2023 View substance registered dossier
(Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide
953-723-7 - Active Intermediate Joint Intermediate use only 22-02-2021 View substance registered dossier
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid
701-116-0 - Active Full Joint ≥ 10 to < 100 tonnes 29-07-2022 View substance registered dossier
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Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2E,4E)-2-methyl-5-phenyl-penta-2,4-dienal 919-772-3 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid 951-764-5 - - View substance registered dossier
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland Ireland Active (2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt 944-007-5 - - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) 947-841-8 - - View substance registered dossier
Pfizer Ltd Ramsgate Road (IPC 979) CT13 9NJ Sandwich Kent United Kingdom United Kingdom No longer Valid (2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate 427-100-0 - 2021 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active (2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1) 920-610-9 - 2021; 2022 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2R,3R)-2,3-Dihydroxybutanedioic acid-(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) 947-840-2 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - 2013 View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride 928-729-8 - 2013 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate 917-473-2 - 2011; 2013 View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2009; 2010; 2017 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Cease Manufacture (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2012 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2010; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
MAPIC Europe NV EXCELSIORLAAN 83 1930 ZAVENTEM Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
B.I.G. - OR634 Technische Schoolstraat 43A 2440 Geel Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2011; 2012; 2014; 2020 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2010; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2014 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2018 View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
TAMARANG, S.A. Balmes, 84, 4-2 08008 Barcelona Barcelona Spain Spain Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2012 View substance registered dossier
[Confidential] - - - (2S)-2-[[(2S)-6-[[2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[(20-tert-butoxy-20-oxo-icosanoyl)amino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-6-(tert-butoxycarbonylamino)-2-[[(2S)-4-tert-butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoyl]amino]hexanoyl]amino]-3-methyl-pentanoyl]amino]propanoyl]amino]-5-oxo-5-(tritylamino)pentanoyl]amino]hexanoyl]amino]propanoic acid 954-943-6 - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hydroxy-3-(substituted)phenyl]-2-alkylpropanoic acid - - - View substance registered dossier
[Confidential] - - - (2S)-2-hydrazinyl-3-[4-hyrdoxy-3-(substituted)phenyl]-2-alkylpropanoic acid — tert-alkylamine (1/1) - - - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary Hungary Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - 2019 View substance registered dossier
Gruenenthal GmbH Zieglerstrasse 6 52078 Aachen Germany Germany Active (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - 2022 View substance registered dossier
- - - - (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (2S)‐2‐{[(2S)‐1‐(2‐{[(benzyloxy)carbonyl]amino}acetyl)‐2‐methylpyrrolidin‐2‐yl]formamido}pentanedioic acid 949-609-1 - - View substance registered dossier
[Confidential] - - - (2S, 4R)-1-((S)-2-(tert-butoxycarbonylamino)-3,3-dimethylbutanoyl)-4-hydroxypyrrolidine-2-carboxylic acid compound with tetrahydrofuran 941-817-0 - - View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1) 947-432-4 - 2018; 2020 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (2S,3S)-2,3-Dihydroxysuccinic acid - (2S)-N-(2,6-dimethylphenyl)-1-propyl-2-piperidinecarboxamide (1:2) 954-871-5 - - View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom No longer Valid (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2021 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2019 View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom No longer Valid (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2021 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (2S,3S)-di-tert-butyl 3-ethyl-4-oxopyrrolidine-1,2-dicarboxylate 942-044-1 - 2017 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate 938-481-2 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (2S,4R)-1-hexadecanoyl-4-hydroxy-pyrrolidine-2-carboxylic acid 944-347-4 - - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid 444-810-6 - 2014; 2021 View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active (2S-cis)-2-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine7,7-dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic acid 444-810-6 - - View substance registered dossier
[Confidential] - - - (3-((6-Chlorohexyl)thio)propyl)triethoxysilane and Hexamethylen-1,6-dithio-bis((3-triethoxysilyl) propane) 951-684-0 - - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (3-(4-((((3β)-cholest-5-en-yl)oxy)carbonyl)phenoxy)propylmethyl-co-3-(4-((2-methyl-2-propenoyloxy)phenyloxy)carbonyl)-phenoxy)propylmethyl)cyclotetrasiloxane) 454-660-3 - - View substance registered dossier
[Confidential] - - - (3-(Formylamino)propyl)dimethylammonioacetate 480-680-7 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (3-Chloro-4-fluoro-phenyl)-{6-nitro-7-[(S)-(tetrahydro-furan-3-yl)oxy]-quinazolin-4-yl}-amine 925-395-5 - 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Cease Manufacture (3-chloropyridin-2-yl)hydrazine 474-260-2 - 2023 View substance registered dossier
Cheminova A/S Thyborønvej 78 DK-7673 Harboøre Denmark Denmark Active (3-chloropyridin-2-yl)hydrazine 474-260-2 - - View substance registered dossier
[Confidential] - - - (3-chloropyridin-2-yl)hydrazine 474-260-2 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (3-fluoro-4'-pentyl[1,1'-biphenyl]-4-yl)-boronic acid 936-618-0 - 2019 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (3-methoxy-2-methylpropyl)benzene 430-150-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (3-methoxy-2-methylpropyl)benzene 430-150-6 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE 443-930-6 - 2010; 2018 View substance registered dossier
DSM Pharma Chemicals Venlo B.V. Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands Netherlands Active (3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE 443-930-6 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5) 931-336-4 - 2019 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate 701-382-8 - - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-4[(4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one 954-618-9 - 2022 View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active (3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 918-279-0 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione 942-823-6 - 2019 View substance registered dossier
- - - - (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate 950-060-5 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate 954-955-1 - - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine 929-011-7 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - 2011; 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
[Confidential] - - - (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (3S,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one 4-methylbenzoate 939-788-4 - - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - 2018 View substance registered dossier
- - - - (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one 427-070-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (4-6) PEPTIDE 427-550-8 - - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active (4-methoxybiphenyl-3-yl)hydrazine hydrochloride 924-885-6 - - View substance registered dossier
- - - - (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] 411-820-7 - - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active (4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate 453-050-4 - 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - 2020 View substance registered dossier
Labcorp Development SA 163 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain Spain Active (4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 700-678-4 - 2019; 2020 View substance registered dossier
Solenis Netherlands B.V. Pesetastraat 62 2991 XT Barendrecht Netherlands Netherlands Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2022; 2023 View substance registered dossier
Solenis Belgium B.V.B.A. Industrieweg 15 3583 Beringen Belgium Belgium Cease Manufacture (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2016 View substance registered dossier
Mare S.p.A. Via Verdi No. 3 20002 Ossona Fraz. Asmonte Italy Italy Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2020 View substance registered dossier
Red Orchid Consulting Oy Ltd Viherkallionkuja 3 I 59 02710 Espoo Finland Finland Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2022 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine 926-346-0 - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - - View substance registered dossier
Visolis, B.V. Urmonderbaan 22 6167 RD Geleen Netherlands Netherlands Active (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
- - - - (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate) 956-466-9 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate 947-346-7 - 2020; 2021; 2023 View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Hovione Limited Loughbeg not available Ringaskiddy County Cork Ireland Ireland Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate 947-931-7 - - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid) 925-915-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - 2022 View substance registered dossier
- - - - (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide 947-800-4 - - View substance registered dossier
Sanofi S.R.L. Viale Luigi Bodio n. 37/b 20158 Milano Italy Italy Active (4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid 443-440-2 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (5-chloro-2-methoxyphenyl)boronic acid 923-256-3 - - View substance registered dossier
[Confidential] - - - (5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine 700-700-2 - - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active (5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine 700-700-2 - 2014; 2018; 2020; 2022 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2017 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2022 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid (6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate 938-716-9 - 2021 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid 921-925-4 - 2022 View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - 2017 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt 439-350-8 - 2021 View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine 921-415-1 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine 918-453-6 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine 917-585-1 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate 949-377-1 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 435-680-1 - 2021 View substance registered dossier
[Confidential] - - - (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - - View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Cease Manufacture (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - 2023 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione 695-945-4 - - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2011; 2018 View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2021 View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - - View substance registered dossier
Minakem High Potent s.a. Rue Fonds Jean Pâques 8 1435 Mont-Saint-Guibert Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - - View substance registered dossier
STERLING CHEMICAL MALTA LTD. HF51, Hal-Far Industrial Estate BBG 3000 Birżebbuġa Malta Malta Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - 2018 View substance registered dossier
AstraZeneca Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom United Kingdom No longer Valid (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - 2021 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one 955-019-5 - - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1) 926-987-6 - 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[25.2.2.0³,⁸]hentriacont-17-en-6-yl]methyl acetate 941-809-7 - 2022 View substance registered dossier
Evonik Fermas s.r.o. Slovenská Ľupča 938 976 13 Slovenská Ľupča Slovakia Slovakia Active (8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[25.2.2.0³,⁸]hentriacont-17-en-6-yl]methyl acetate 941-809-7 - 2016; 2019; 2021; 2022 View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active (alpha-cyanobenzyl)malonic acid diethyl ester 922-463-6 - - View substance registered dossier
RSI ChemRep Europe Ltd (S001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active (aminoalkyl) hydrogen thiosulfate - - 2017; 2021 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate 442-520-4 - 2017 View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate 442-520-4 - 2020 View substance registered dossier
Archroma Ibérica, S.L. - OR ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Cease Manufacture (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate 442-520-4 - 2020 View substance registered dossier
- - - - (C14-C30-alkyl)phenyl-3-tolyliodonium trifluoromethansulfonate 424-410-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (C14/C16/C18) n-alkyl (of non animal origin)benzyl dimethyl ammonium chloride compound with bentonite 436-020-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (C16 or C18-n-alkyl)(C16 or C18-n-alkyl)ammonium 2-((C16 or C18-n-alkyl)(C16 or C18-n-alkyl)carbamoyl)benzenesulfonate 402-460-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (C16 or C18-n-alkyl)(C16 or C18-n-alkyl)ammonium 2-((C16 or C18-n-alkyl)(C16 or C18-n-alkyl)carbamoyl)benzenesulfonate 402-460-1 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine 700-519-9 - 2017 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine 700-519-9 - - View substance registered dossier
- - - - (D)-2-BROM-3-PHENYLPROPIONSÄURE-ETHYLENDIAMINSALZ 447-890-0 - - View substance registered dossier
Deretil S.A.U. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Cease Manufacture (D)-p-hydroxyphenylglycine-2-hydroxyethylester, hydrochloride 433-310-3 - 2023 View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active (D)-p-hydroxyphenylglycine-2-hydroxyethylester, hydrochloride 433-310-3 - - View substance registered dossier
ABCR Laboratorios, S.L. Poligono Industrial de Vilapouca 36555 Forcarei Galicia Spain Spain Active (Dimethoxy(methyl)silyl)methyl 2-methacrylate 479-600-3 - - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (Dimethoxy(methyl)silyl)methyl 2-methacrylate 479-600-3 - 2016 View substance registered dossier
[Confidential] - - - (E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone - - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime 456-110-8 - 2017; 2022 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime 456-110-8 - 2011; 2014; 2015 View substance registered dossier
[Confidential] - - - (E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one - - - View substance registered dossier
Only representative (No publishable name) - - Active (E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate 944-280-0 - - View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active (E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate 944-280-0 - - View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active (E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate 944-280-0 - 2020 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (E)-2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-ylmethylene)-5,6-dimethoxy-indan-1-one hydrochloride 940-983-1 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenyl-amino)-7-((S)-(tetrahydrofuran-3-yl)oxy)-quinazoline-6-yl]-amide 923-981-5 - 2015; 2023 View substance registered dossier
Solvay Fluor GmbH Hans-Boeckler-Allee 20 30173 HANNOVER Germany Germany Active (E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT) 475-900-3 - 2010; 2014; 2019 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (E)-ethyl 4-(dimethylamino)but-2-enoate maleate 941-772-7 - 2015 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active (E)-Ethyl 4-oxo-but-2-enoate 438-470-8 - 2021; 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (E)-Ethyl 4-oxo-but-2-enoate 438-470-8 - - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (E)-N'-hydroxy-N-(4-hydroxypyrid-2-yl)formimidamide 952-647-1 - - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine 449-170-1 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine 449-170-1 - - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine 449-170-1 - 2017 View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide - - 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (ethyl-1,2-ethanediyl)]-2-[[[(2-hydroxyethyl)methylamino]acetyl]propyl]ω-(nonylphenoxy)poly[oxy(methyl-1,2-ethanediyl) 418-960-8 - - View substance registered dossier
- - - - (imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride 415-470-6 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate) 950-860-4 - 2020 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate) 950-860-4 - - View substance registered dossier
Alzchem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active (N-phenylcarbamimidoyl)ammonium carbonate hydrate 485-350-6 - 2009; 2019 View substance registered dossier
[Confidential] - - - (N-phenylcarbamimidoyl)ammonium carbonate hydrate 485-350-6 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (n-{(1s,3s)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide hydrochloride) 952-248-2 - 2020 View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (NZ)-N-[1-(2,4-dichlorophenyl)-2-imidazol-1-ylethylidene]hydroxylamine 917-661-4 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (R)-1-(1H-benzo[d]imidazol-4-yl)propan-2-amine dihydrochloride 956-605-3 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (R)-1-(1H-indazol-4-yl)-N-(2,2,2-trifluoroethyl)propan-2-amine 10-camphorsulfonic acid salt 956-342-4 - - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid 941-846-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - - View substance registered dossier
Deretil S.A.U. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Cease Manufacture (R)-1-cyclohexa-1,4-dienyl-1-methoxycarbonyl-methylammoniumchloride 444-320-2 - 2019 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol 929-946-0 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-2-[3-(Diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol (R)-acetoxy(phenyl)acetate 929-947-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-acetamido-3-naphthyl-2-yl-propionic acid 440-450-9 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - 2018; 2021 View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France No longer Valid (R)-2-dimethylamino-4-imino-6-methyl-1,4,5,6-tetrahydro-1,3,5-triazine, L-tartrate 942-402-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(4-chlorophenyl)propionic acid 438-070-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (R)-2-tert-butoxycarbonylamino-3-(pyridin-3-yl)propionic acid 441-200-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (R)-3-(1-methyl-2-pyrrolidinylmethyl)-5-[2-(phenylsulphonyl)ethyl]-1H-indole 921-685-0 - - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R)-4-(4-dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile hemi (2R, 3R)-2,3-bis((4-methylbenzoyl)oxy)succinoate 949-784-4 - - View substance registered dossier
Synthon, s.r.o. Brněnská 32 678 01 Blansko Czech Republic Czech Republic Active (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide (7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate 920-209-9 - - View substance registered dossier
Astellas Ireland Co.Ltd Damastown Road Damastown Industrial Park NA Mulhuddart Dublin 15 Ireland Ireland Active (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide 419-800-1 - 2019 View substance registered dossier
- - - - (R)-5-(2-Aminopropyl)-2-methoxybenzenesulfonamide 419-800-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Danish competent national authority. - - Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate 430-790-6 - - View substance registered dossier
Lundbeck Pharmaceuticals Italy S.p.A via quarta strada 2 35129 padova Italy Italy Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate 430-790-6 - 2015 View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active (R,S)-4-(4-dimethylamino-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)-benzonitrile hemisulfate 430-790-6 - 2015; 2018 View substance registered dossier
Plixxent B.V. Korte Groningerweg 1A 9607 Foxhol Netherlands Netherlands Active (Reaction product of 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, 2-(2-hydroxyethylamino)ethanol and formaldehyde), propoxylated 926-000-9 - 2013; 2016; 2017; 2018; 2021; 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine 434-800-1 - - View substance registered dossier
Bayer Agriculture bvba Scheldelaan 460 B-2040 Antwerp Belgium Belgium Cease Manufacture (RS)-3-dichloroacetyl-5-(2-furanyl)-2,2-dimethyloxazolidine 434-800-1 - 2020 View substance registered dossier
Bábolna Bioenvironmental Centre Private Limited Company Szállás u. 6. H-1107 Budapest Hungary Hungary Active (S) (2Z,4E)-4-carboxy-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid disodium salt 918-890-2 - - View substance registered dossier
Carbogen Amcis Ltd 303 Clayton Lane M11 4SX Manchester Greater Manchester United Kingdom United Kingdom No longer Valid (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-(-)-tetrahydro-2-furoic acid 433-770-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (S)-1,2,4-butanetriyltrimethanesulfonate 433-850-1 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (S)-2,6-Diamino-4,5,6,7-tetrahydrobenzothiazole Tartrat Trihydrate 928-472-1 - 2021 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-2-(1-aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one hydrochloride 942-180-1 - 2017 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-trityl-1H-imidazol-4-yl)propanamido)-2-methylpropanoic acid 951-381-3 - 2021 View substance registered dossier
[Confidential] - - - (S)-2-(5-Methylheteromonocycle-2-carboxamido)-alkenoic acid - - - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 - 2019; 2020; 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 - - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Cease Manufacture (S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propionic acid 439-640-4 - 2019 View substance registered dossier
B-Lands Consulting (811587-0) World Trade Center, 5 Place Robert Schuman, BP 1516 38025 Grenoble France France France Active (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 - - View substance registered dossier
[Confidential] - - - (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (S)-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 431-910-1 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (S)-3-[1-(Dimethylamino)ethyl]-phenol 478-670-2 - - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (S)-3-[1-(Dimethylamino)ethyl]-phenol 478-670-2 - 2010 View substance registered dossier
- - - - (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
[Confidential] - - - (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyloxazolidin-2-one 480-320-9 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (S)-3-Hydroxytetrahydrofurane 425-090-2 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2017 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (S)-3-Hydroxytetrahydrofurane 425-090-2 - 2017 View substance registered dossier
- - - - (S)-4-amino-5-[(2-(1H-imidazol-4-yl)ethyl)amino]-5-oxopentanoic acid 421-900-3 - - View substance registered dossier
bracco imaging Via Folli 50 20134 milan Italy Italy Active (S)-5-[2-(acetyloxy)propanamido]-2,4,6-triiodo-1,3-di(chloroformyl)benzene 410-940-7 - 2022 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-5-chloro-4-methyl-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole dihydrochloride 948-271-2 - - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture (S)-6-(2-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-oxoethyl) 5-tert-butyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate 941-125-9 - 2021 View substance registered dossier
- - - - (S)-7-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one glucopyranosyl ether 471-940-0 - - View substance registered dossier
MinAscent Leuna Production GmbH Am Haupttor Gebäude 4208 06237 Leuna Germany Germany Active (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
- - - - (S)-[2-(phenylmethoxy)propylidene]hydrazinecarboxylate, tert-butyle 439-220-0 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - 2022 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (S)-ethyl 3-(4,4-difluorocyclohexanecarboxamido)-3-phenylpropanoate 445-820-3 - 2021 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (S)-ethyl-3-amino-3-phenylpropanoate hemi (2S,3S)-2,3-dihydroxysuccinate 955-403-2 - - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (S)-N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-amine 942-077-1 - - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate 924-425-4 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (S)-propane-1,2-diamine bis((2S,3S)-2,3-dihydroxysuccinate) dihydrate 924-425-4 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture (S)-tert-butyl(1-((3-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxobutan-2 yl)carbamate 942-159-7 - 2017 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (S)-tert.-Butyl-[2-(aminoethoxy)-[1,2]oxaborolan-4-yl]acetate 942-682-0 - - View substance registered dossier
Bábolna Bioenvironmental Centre Private Limited Company Szállás u. 6. H-1107 Budapest Hungary Hungary Active (S)Ammonium-(2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate 926-381-1 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (trans(trans))-4'-but-3-enyl-4-(4-methylphenyl)-bicyclohexyl 429-580-7 - 2010; 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (trans(trans))-4'-vinyl-4-(4-methylphenyl)bicyclohexyl 439-730-3 - 2009; 2010; 2011; 2012; 2014; 2019 View substance registered dossier
ABCR Laboratorios, S.L. Poligono Industrial de Vilapouca 36555 Forcarei Galicia Spain Spain Active (Trimethoxysilyl)methyl 2-methacrylate 454-220-0 - - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (Trimethoxysilyl)methyl 2-methacrylate 454-220-0 - 2016 View substance registered dossier
Nouryon Functional Chemicals B.V. Haaksbergweg 88 1101 BZ Amsterdam The Netherlands Netherlands Netherlands Cease Manufacture (TRIMETHYLENEDINITRILO)TETRAKISACETONITRILE 429-330-7 - 2014 View substance registered dossier
- - - - (trimethylvinylsilyl)hexafluoroacetylacetonato copper I 435-140-5 - - View substance registered dossier
ALCOVER QUIMICA S.L. CARRETERA MONTBLANC Km 24 43460 ALCOVER Spain Spain Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2018 View substance registered dossier
Habrinol Decin Tovarni 63 407 11 Decin XXXII Decin Czech Republic Czech Republic Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019; 2023 View substance registered dossier
Innospec Performance Chemicals France SAS Zone Industrielle de Han Sur Meuse BP19 55300 Saint-Mihiel France France Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2017; 2018; 2022 View substance registered dossier
PHARMEGIC HEALTHCARE LIMITED 6th Floor, Konstitucijos av. 21A, 08130 Vilnius Lithuania Ireland Ireland Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - - View substance registered dossier
STEPAN EUROPE SAS OR chemin Jongkind CS 20127 38341 VOREPPE France France Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2018; 2021 View substance registered dossier
Experien Chemical Services (Ireland) Limited Unit 3D North Point House North Point Business Park, New Mallow Road TS23 AT2P Cork Ireland Ireland Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019; 2021 View substance registered dossier
Charles River Laboratories Den Bosch B.V. OR63 Hambakenwetering 7 5231DD 's-Hertogenbosch Netherlands Netherlands Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019 View substance registered dossier
CAVENAGHI SPA via Varese 19 20020 lainate Italy Italy Active (xylenes and 4-ethylbenzene)sulfonic acids 701-247-3 - 2019 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (Z)-3-(chloro((2-hydroxy-3-(piperidin-1-yl)propoxy)imino)methyl)pyridine 1-oxide 953-723-7 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid 701-116-0 - 2013; 2016; 2017; 2020; 2021; 2022 View substance registered dossier
[Confidential] - - - (Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid 701-116-0 - - View substance registered dossier
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In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

 

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