Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
Methyl (1R,21S,24S)-21-tert-butyl-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.1^4,7 .0. ^6,11] ]heptacosa-6,8,10-triene-24-carboxylate
618-840-7 923591-06-4 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
METHYL (1R,2R,4S)-2-[HEX-5-EN-1-YL(METHYL)CARBAMOYL]-4-({7-METHOXY-8-METHYL-2-[4-(PROPAN-2-YL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)CYCLOPENTANECARBOXYLATE
922-147-8 - Cease Manufacture Full Joint Cease manufacture 22-08-2017 View substance registered dossier
methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate hydrochloride
611-400-5 565456-77-1 Active Intermediate Joint Intermediate use only 24-05-2022 View substance registered dossier
Methyl (1R,3S,4R,5R)-3-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)carbonyl]amino}-5-({2,4,6-tri-O-benzoyl-3-O-[(2S)-1-(benzyloxy)-3-cyclohexyl-1-oxopropan-2-yl]-β-Dgalactopyranosyl}oxy)-4-[(2,3,4-tri-O-benzyl-6-deoxy-α-L-galactopyranosyl)oxy]cyclohexanecarboxylate
816-314-3 927881-65-0 Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
methyl (2,3-dichlorophenoxy)acetate
606-285-3 1928-56-9 Active Intermediate Joint Intermediate use only 02-03-2018 View substance registered dossier
Methyl (2E)-2-[(2,3-dichlorophenyl)methylidene]-3-oxobutanoate
616-044-4 74073-22-6 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
Methyl (2E)-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)prop-2-enoate
700-526-7 1333488-95-1 Active Intermediate Joint Intermediate use only 18-11-2015 View substance registered dossier
methyl (2R)-2-[(3-chloropropyl)amino]propanoate hydrochloride
947-864-3 2222933-72-2 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
methyl (2R)-2-amino-3-phenylpropanoate hydrochloride
945-660-9 - Active Intermediate Joint Intermediate use only 29-03-2018 View substance registered dossier
methyl (2R)-2-amino-3-phenylpropanoate;hydrochloride
603-406-1 13033-84-6 Active Intermediate Joint Intermediate use only 16-12-2019 View substance registered dossier
methyl (2R)-2-fluoropropanoate
478-990-2 - Active Intermediate Joint Intermediate use only 24-11-2022 View substance registered dossier
methyl (2S)-2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5-oxo-5-{4-[(phenylmethyl)oxy]phenyl}pentanoate
815-197-6 934240-37-6 Cease Manufacture Intermediate Joint Cease manufacture 27-03-2018 View substance registered dossier
Methyl (2S,4R)-1-benzoyl-4-(methanesulfonyloxy)pyrrolidine-2-carboxylate
814-265-2 176439-43-3 Active Intermediate Joint Intermediate use only 10-11-2021 View substance registered dossier
Methyl (2S-trans)-6,8-dideoxy-6-[[(1-methyl-4-propylpyrrolidin-2-yl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside monohydrochloride
212-726-7 859-18-7 Active Intermediate Joint Intermediate use only 17-03-2022 View substance registered dossier
Methyl (3-hydroxyphenyl)-carbamate
237-196-4 13683-89-1 Active Intermediate Joint Intermediate use only 04-07-2012 View substance registered dossier
METHYL (3-OXO-2-PENTYLCYCLOPENT-1-EN-1-YL)ACETATE
431-410-1 - Active Intermediate Joint Intermediate use only 27-04-2017 View substance registered dossier
Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate
GR138766X
415-670-3 78850-37-0 Cease Manufacture Intermediate Joint Cease manufacture 20-01-2010 View substance registered dossier
Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate
GR138766X
415-670-3 78850-37-0 No longer Valid NONS Joint No longer valid 10-11-2008 View substance registered dossier
methyl (3E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenoate
607-380-2 244626-75-3 Active Intermediate Joint Intermediate use only 21-02-2020 View substance registered dossier
methyl (3Z)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenoate
847-736-6 2001653-49-0 Active Intermediate Joint Intermediate use only 05-03-2020 View substance registered dossier
methyl (4-butanoyl-2,3-dichlorophenoxy)acetate
608-516-3 30720-99-1 Active Intermediate Joint Intermediate use only 02-03-2018 View substance registered dossier
Methyl (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate
600-422-0 103335-41-7 Active Intermediate Joint Intermediate use only 08-04-2019 View substance registered dossier
methyl (4E)-octa-4,7-dienoate
422-840-0 189440-77-5 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
methyl (5S)-2,3,4-tri-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1-thio-beta-L-xylopyranoside
814-200-8 1018899-03-0 Active Intermediate Joint Intermediate use only 15-10-2020 View substance registered dossier
methyl (7R,10S,13S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-carboxylate
619-164-5 95716-70-4 Active Intermediate Joint Intermediate use only 09-07-2019 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Methyl (1R,21S,24S)-21-tert-butyl-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.1^4,7 .0. ^6,11] ]heptacosa-6,8,10-triene-24-carboxylate 618-840-7 923591-06-4 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture METHYL (1R,2R,4S)-2-[HEX-5-EN-1-YL(METHYL)CARBAMOYL]-4-({7-METHOXY-8-METHYL-2-[4-(PROPAN-2-YL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)CYCLOPENTANECARBOXYLATE 922-147-8 - 2021 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate hydrochloride 611-400-5 565456-77-1 - View substance registered dossier
[Confidential] - - - methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate hydrochloride 611-400-5 565456-77-1 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active methyl (1R,2S,5S)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylate hydrochloride 611-400-5 565456-77-1 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active Methyl (1R,3S,4R,5R)-3-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)carbonyl]amino}-5-({2,4,6-tri-O-benzoyl-3-O-[(2S)-1-(benzyloxy)-3-cyclohexyl-1-oxopropan-2-yl]-β-Dgalactopyranosyl}oxy)-4-[(2,3,4-tri-O-benzyl-6-deoxy-α-L-galactopyranosyl)oxy]cyclohexanecarboxylate 816-314-3 927881-65-0 - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active methyl (2,3-dichlorophenoxy)acetate 606-285-3 1928-56-9 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active Methyl (2E)-2-[(2,3-dichlorophenyl)methylidene]-3-oxobutanoate 616-044-4 74073-22-6 - View substance registered dossier
PCAS Finland Oy Messukentänkatu 8 20210 TURKU Finland Finland Active Methyl (2E)-2-[(2,3-dichlorophenyl)methylidene]-3-oxobutanoate 616-044-4 74073-22-6 - View substance registered dossier
[Confidential] - - - Methyl (2E)-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)prop-2-enoate 700-526-7 1333488-95-1 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid Methyl (2E)-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)prop-2-enoate 700-526-7 1333488-95-1 2021 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active methyl (2R)-2-[(3-chloropropyl)amino]propanoate hydrochloride 947-864-3 2222933-72-2 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active methyl (2R)-2-amino-3-phenylpropanoate hydrochloride 945-660-9 - - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active methyl (2R)-2-amino-3-phenylpropanoate;hydrochloride 603-406-1 13033-84-6 - View substance registered dossier
Blue Frog Scientific EURL - EU OR18 967 Route de la Plaine La Plaine 26400 Chabrillan France France Active methyl (2R)-2-fluoropropanoate 478-990-2 - 2012; 2014 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active methyl (2R)-2-fluoropropanoate 478-990-2 - 2022 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Cease Manufacture methyl (2S)-2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-5-oxo-5-{4-[(phenylmethyl)oxy]phenyl}pentanoate 815-197-6 934240-37-6 2022 View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active Methyl (2S,4R)-1-benzoyl-4-(methanesulfonyloxy)pyrrolidine-2-carboxylate 814-265-2 176439-43-3 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active Methyl (2S-trans)-6,8-dideoxy-6-[[(1-methyl-4-propylpyrrolidin-2-yl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside monohydrochloride 212-726-7 859-18-7 2022 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active Methyl (2S-trans)-6,8-dideoxy-6-[[(1-methyl-4-propylpyrrolidin-2-yl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside monohydrochloride 212-726-7 859-18-7 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active Methyl (3-hydroxyphenyl)-carbamate 237-196-4 13683-89-1 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active METHYL (3-OXO-2-PENTYLCYCLOPENT-1-EN-1-YL)ACETATE 431-410-1 - 2010; 2017 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate 415-670-3 78850-37-0 2019 View substance registered dossier
SmithKline Beecham plc 980 Great West Road TW8 9GS Brentford Middlesex United Kingdom United Kingdom No longer Valid Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate 415-670-3 78850-37-0 2021 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid Methyl (3aR,4R,7aR)-2-methyl-4-(1S,2R,3-triacetoxypropyl)-3a,7a-dihydro-4H-pyrano[3,4-d]oxazole-6-carboxylate 415-670-3 78850-37-0 2021 View substance registered dossier
[Confidential] - - - methyl (3E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenoate 607-380-2 244626-75-3 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active methyl (3E)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenoate 607-380-2 244626-75-3 - View substance registered dossier
[Confidential] - - - methyl (3Z)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenoate 847-736-6 2001653-49-0 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active methyl (3Z)-4-methyl-6-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-hexenoate 847-736-6 2001653-49-0 2020 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active methyl (4-butanoyl-2,3-dichlorophenoxy)acetate 608-516-3 30720-99-1 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Methyl (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate 600-422-0 103335-41-7 - View substance registered dossier
- - - - methyl (4E)-octa-4,7-dienoate 422-840-0 189440-77-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active methyl (4E)-octa-4,7-dienoate 422-840-0 189440-77-5 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active methyl (5S)-2,3,4-tri-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1-thio-beta-L-xylopyranoside 814-200-8 1018899-03-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active methyl (5S)-2,3,4-tri-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1-thio-beta-L-xylopyranoside 814-200-8 1018899-03-0 - View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active methyl (7R,10S,13S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-carboxylate 619-164-5 95716-70-4 2019 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.