Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate
BIBR 1048 MANAMIDE
454-450-1 - Active Intermediate Joint Intermediate use only 20-11-2019 View substance registered dossier
Ethyl 3-(2,4-dimethyl-1,3-dioxolan-2-yl)propanoate
700-636-5 5413-49-0 Active Full Joint ≥ 0 to < 10 tonnes 04-02-2022 View substance registered dossier
Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride
801-940-1 211914-50-0 Active Intermediate Joint Intermediate use only 21-02-2023 View substance registered dossier
Ethyl 3-(chloroformyl)propionate
238-855-9 14794-31-1 Active Intermediate Joint Intermediate use only 05-02-2018 View substance registered dossier
Ethyl 3-(diethylamino)propionate
226-859-3 5515-83-3 Active Intermediate Joint Intermediate use only 03-12-2014 View substance registered dossier
Ethyl 3-(triethoxysilyl)propylcarbamate
241-872-4 17945-05-0 Active Intermediate Joint Intermediate use only 30-01-2018 View substance registered dossier
ethyl 3-[(3R)-3-{[(1S)-1-phenylethyl]amino}-2,3,4,9-tetrahydro-1H-carbazol-9-yl]propanoate
811-937-7 1638586-33-0 Active Intermediate Joint Intermediate use only 15-03-2016 View substance registered dossier
Ethyl 3-[(5-chloro-2-nitrophenyl)phenylamino]-3-oxopropionate
244-907-1 22316-45-6 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
Ethyl 3-[4-(hydroxymethyl)-2-methyl-1,3-dioxolan-2-yl]propanoate
700-637-0 902272-78-0 Active Full Joint ≥ 0 to < 10 tonnes 04-02-2022 View substance registered dossier
Ethyl 3-[[bis(1-methylethoxy)phosphinothioyl]thio]propionate
275-965-6 71735-74-5 Active Full Joint ≥ 100 to < 1 000 tonnes 18-02-2022 View substance registered dossier
Ethyl 3-amino-1H-pyrazole-4-carboxylate
230-262-3 6994-25-8 Active Intermediate Joint Intermediate use only 10-05-2013 View substance registered dossier
ethyl 3-amino-3-phenylpropanoate
613-206-6 6335-76-8 Active Intermediate Joint Intermediate use only 27-02-2017 View substance registered dossier
Ethyl 3-amino-4-[2-(phthalimido)ethoxy]crotonate
700-069-3 265136-65-0 Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
Ethyl 3-aminocrotonate
230-782-0 7318-00-5 Active Intermediate Joint Intermediate use only 11-12-2020 View substance registered dossier
Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate
610-491-9 500011-92-7 Active Intermediate Joint Intermediate use only 08-10-2020 View substance registered dossier
Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate
805-389-8 500011-91-6 Active Intermediate Joint Intermediate use only 21-09-2020 View substance registered dossier
Ethyl 3-chloro-3-oxopropionate
252-934-5 36239-09-5 Active Intermediate Joint Intermediate use only 25-01-2022 View substance registered dossier
Ethyl 3-ethoxy-3-iminopropionate hydrochloride
219-028-1 2318-25-4 Active Intermediate Joint Intermediate use only 11-05-2018 View substance registered dossier
Ethyl 3-ethoxypropionate
212-112-9 763-69-9 Active Full Joint ≥ 1 000 to < 10 000 tonnes 22-11-2022 View substance registered dossier
Ethyl 3-oxohexanoate
221-835-9 3249-68-1 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
Ethyl 3-phenyloxirane-2-carboxylate
204-467-3 121-39-1 Active Full Joint ≥ 1 to < 10 tonnes 25-01-2018 View substance registered dossier
Ethyl 4,4,4-trifluoroacetoacetate
206-750-7 372-31-6 Cease Manufacture Full Joint Cease manufacture 11-01-2013 View substance registered dossier
Ethyl 4,4,4-trifluoroacetoacetate
206-750-7 372-31-6 Active Intermediate Joint Intermediate use only 29-10-2019 View substance registered dossier
Ethyl 4,4-dimethoxy-3-methyl-2-butenoate
280-901-5 83803-81-0 Active Intermediate Joint Intermediate use only 04-07-2016 View substance registered dossier
Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate
604-436-8 144690-33-5 Active Intermediate Joint Intermediate use only 04-01-2021 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate 454-450-1 - 2015 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate 454-450-1 - 2012; 2013; 2014; 2019 View substance registered dossier
GFB Europe B.V. (OR) Urmonderbaan 22 6167 RD Geleen Netherlands Netherlands Active Ethyl 3-(2,4-dimethyl-1,3-dioxolan-2-yl)propanoate 700-636-5 5413-49-0 2013; 2018; 2020; 2022 View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride 801-940-1 211914-50-0 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochloride 801-940-1 211914-50-0 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active Ethyl 3-(chloroformyl)propionate 238-855-9 14794-31-1 - View substance registered dossier
SD Agchem (Europe) NV Uitbreidingstraat 84/3, 2600 Berchem, Belgium Belgium Belgium Active Ethyl 3-(chloroformyl)propionate 238-855-9 14794-31-1 - View substance registered dossier
A.C.R.A.F. Spa Via Amelia 70 00181 Roma Italy Italy Active Ethyl 3-(diethylamino)propionate 226-859-3 5515-83-3 - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active Ethyl 3-(triethoxysilyl)propylcarbamate 241-872-4 17945-05-0 2018 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active ethyl 3-[(3R)-3-{[(1S)-1-phenylethyl]amino}-2,3,4,9-tetrahydro-1H-carbazol-9-yl]propanoate 811-937-7 1638586-33-0 2016 View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active Ethyl 3-[(5-chloro-2-nitrophenyl)phenylamino]-3-oxopropionate 244-907-1 22316-45-6 2021; 2022 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Ethyl 3-[(5-chloro-2-nitrophenyl)phenylamino]-3-oxopropionate 244-907-1 22316-45-6 2017 View substance registered dossier
GFB Europe B.V. (OR) Urmonderbaan 22 6167 RD Geleen Netherlands Netherlands Active Ethyl 3-[4-(hydroxymethyl)-2-methyl-1,3-dioxolan-2-yl]propanoate 700-637-0 902272-78-0 2013; 2018; 2020; 2022 View substance registered dossier
Afton Chemical S.R.L. (Woluwe) Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium Belgium Active Ethyl 3-[[bis(1-methylethoxy)phosphinothioyl]thio]propionate 275-965-6 71735-74-5 - View substance registered dossier
[Confidential] - - - Ethyl 3-[[bis(1-methylethoxy)phosphinothioyl]thio]propionate 275-965-6 71735-74-5 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active Ethyl 3-[[bis(1-methylethoxy)phosphinothioyl]thio]propionate 275-965-6 71735-74-5 2018; 2022 View substance registered dossier
Colors & Effects France S.A.S. Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture Ethyl 3-[[bis(1-methylethoxy)phosphinothioyl]thio]propionate 275-965-6 71735-74-5 2015 View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active Ethyl 3-amino-1H-pyrazole-4-carboxylate 230-262-3 6994-25-8 - View substance registered dossier
Sicor - Società Italiana Corticosteroidi S.r.l. Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy Italy Active Ethyl 3-amino-1H-pyrazole-4-carboxylate 230-262-3 6994-25-8 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active ethyl 3-amino-3-phenylpropanoate 613-206-6 6335-76-8 2017 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active Ethyl 3-amino-4-[2-(phthalimido)ethoxy]crotonate 700-069-3 265136-65-0 2010; 2012; 2015 View substance registered dossier
PCAS Finland Oy Messukentänkatu 8 20210 TURKU Finland Finland Active Ethyl 3-aminocrotonate 230-782-0 7318-00-5 - View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active Ethyl 3-aminocrotonate 230-782-0 7318-00-5 2020 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid Ethyl 3-aminocrotonate 230-782-0 7318-00-5 2021 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active Ethyl 3-aminocrotonate 230-782-0 7318-00-5 - View substance registered dossier
[Confidential] - - - Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylate 610-491-9 500011-92-7 - View substance registered dossier
[Confidential] - - - Ethyl 3-bromo-1-(3-chloropyridin-2-yl)-4,5-dihydro-1H-pyrazole-5-carboxylate 805-389-8 500011-91-6 - View substance registered dossier
EUROAPI FRANCE 15 rue Traversière 75012 Paris France France Active Ethyl 3-chloro-3-oxopropionate 252-934-5 36239-09-5 2021; 2022 View substance registered dossier
CHEMI S.p.A. Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy Italy Active Ethyl 3-ethoxy-3-iminopropionate hydrochloride 219-028-1 2318-25-4 - View substance registered dossier
JSR Micro n.v. Technologielaan 8 3001 Leuven Belgium Belgium Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
PPG Europe B.V. in its legal capacity as Only Representative of PRC DeSoto International Inc. - OR5 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
DOW BENELUX B.V. OR-27 Postbus 48 4350 AA Terneuzen Netherlands Netherlands Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 2014; 2021 View substance registered dossier
PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc. Via Serra, 1 15028 Quattordio Italy Italy Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 2020 View substance registered dossier
AGC Chemicals Europe, Ltd World Trade Centre Zuidplein 80 1077XV Amsterdam Netherlands Netherlands Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland Ireland Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
AKZO Nobel Car Refinishes B.V. Rijksstraatweg 31 2170 BA Sassenheim Netherlands Netherlands Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
Eastman Chemical Workington Limited Siddick CA14 1LG Workington Cumbria United Kingdom United Kingdom No longer Valid Ethyl 3-ethoxypropionate 212-112-9 763-69-9 2021 View substance registered dossier
PPG Europe B.V. - OR3 Amsterdamseweg 14 1422 AD Uithoorn Netherlands Netherlands Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
3M Belgium BVBA/SPRL (OR1) Hermeslaan 7 1831 Diegem Belgium Belgium Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
Dow Belgium B.V.B.A. Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium Belgium Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 2021 View substance registered dossier
DOW BENELUX B.V. OR-31 Postbus 48 4350 AA Terneuzen Netherlands Netherlands Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 2021 View substance registered dossier
Eastman Chemical B.V. Watermanweg 70 3067 GG Rotterdam Netherlands Netherlands Active Ethyl 3-ethoxypropionate 212-112-9 763-69-9 - View substance registered dossier
HERBRAND PharmaChemicals GmbH Brambachstraße 31 77723 Gengenbach B-W Germany Germany Active Ethyl 3-oxohexanoate 221-835-9 3249-68-1 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl 3-oxohexanoate 221-835-9 3249-68-1 - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active Ethyl 3-phenyloxirane-2-carboxylate 204-467-3 121-39-1 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Cease Manufacture Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 2022 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 - View substance registered dossier
YOU Solutions Germany GmbH - REACH (part of Arxada) Freundallee 9 a 30173 Hannover Germany Germany Active Ethyl 4,4,4-trifluoroacetoacetate 206-750-7 372-31-6 2017 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Ethyl 4,4-dimethoxy-3-methyl-2-butenoate 280-901-5 83803-81-0 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate 604-436-8 144690-33-5 2021 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.