Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
ethyl (2E)-3-(cyclopropylamino)-2-[(2,4-dichloro-3-methylphenyl)carbonyl]prop-2-enoate
953-808-9 - Active Full Joint ≥ 1 to < 10 tonnes 28-07-2021 View substance registered dossier
Ethyl (2E,4Z)-2,4-decadienoate
221-178-8 3025-30-7 Active Full Joint ≥ 1 to < 10 tonnes 07-04-2020 View substance registered dossier
ETHYL (2R,3AR,10Z,11AS,12AR,14AR)-2-({7-METHOXY-8-METHYL-2-[4-(PROPAN-2-YL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)-5-METHYL-4,14-DIOXO-2,3,3A,4,5,6,7,8,9,11A,12,13,14,14A-TETRADECAHYDROCYCLOPENTA[C]CYCLOPROPA[G][1,6]DIAZACYCLOTETRADECINE-12A(1H)-CARBOXYLATE
618-843-3 923604-57-3 Cease Manufacture Full Joint Cease manufacture 08-08-2017 View substance registered dossier
ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate
430-360-8 84793-24-8 Active Intermediate Joint Intermediate use only 16-04-2021 View substance registered dossier
ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate
430-360-8 84793-24-8 Active NONS Joint Tonnage data confidential 26-02-2020 View substance registered dossier
ethyl (2S,3S)-3-[(2-chloro-5-fluoro-4-pyrimidinyl)amino]bicyclo[2.2.2]octane-2-carboxylate
821-183-0 1777721-57-9 Cease Manufacture Full Joint Cease manufacture 28-02-2019 View substance registered dossier
ethyl (2S,3S)-3-aminobicyclo[2.2.2]octane-2-carboxylate monohydrochloride
812-619-0 1626394-43-1 Cease Manufacture Full Joint Cease manufacture 18-12-2018 View substance registered dossier
ethyl (2Z)-2-[2-(4-chlorophenyl)hydrazinylidene]-3-(2,6-dichlorophenyl)-3-oxopropanoate
609-702-7 395068-96-9 Cease Manufacture Intermediate Joint Cease manufacture 04-09-2017 View substance registered dossier
ethyl (3-benzoyl-2,4,6-trimethylbenzoyl)(phenyl)phosphinate
806-801-9 1539267-56-5 Active Full Joint ≥ 0 to < 10 tonnes 18-02-2021 View substance registered dossier
ethyl (3-cyanomethyl-3,4-dihydro-4-oxophthalazin-1-yl)acetate
429-680-0 122665-86-5 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
Ethyl (3aR,7R,7aR)-2,2-dimethyl-7-[(methylsulfonyl)oxy]-3a,6,7,7a-tetrahydro-1,3-benzodioxole-5-carboxylate
606-548-2 204254-84-2 Active Intermediate Joint Intermediate use only 01-10-2019 View substance registered dossier
ethyl (3R)-3-hydroxybutanoate
695-003-2 24915-95-5 No longer Valid Intermediate Joint No longer valid 13-12-2018 View substance registered dossier
ethyl (3R)-4-cyano-3-hydroxybutanoate
430-220-6 141942-85-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
Ethyl (3R,4R,5S)-4-acetamido-5-azido-3-(1-ethylpropoxy)cyclohex-1-enecarboxylate
433-320-8 - Active Intermediate Joint Intermediate use only 31-03-2023 View substance registered dossier
Ethyl (3R,4S,5R)-5-azido-3-(1-ethylpropoxy)-4-hydroxycyclohex-1-ene-1-carboxylate
805-633-3 204254-98-8 Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
Ethyl (4-chlorophenyl)acetate
237-906-2 14062-24-9 Active Intermediate Joint Intermediate use only 18-06-2020 View substance registered dossier
Ethyl (4-methylphenoxy)acetate
266-554-2 67028-40-4 Active Intermediate Joint Intermediate use only 20-07-2018 View substance registered dossier
Ethyl (4S, 5R)-5-(3,4-bis(benzyloxy)phenyl)-4,5-dihydrooxazole-4-carboxylate
955-411-6 1129484-93-0 Active Intermediate Joint Intermediate use only 08-02-2022 View substance registered dossier
Ethyl (6-bromo-pyridin-2-ylamino)carbonothioylcarbamate
850-733-2 1010120-59-8 Active Intermediate Joint Intermediate use only 01-04-2022 View substance registered dossier
Ethyl (E)-4-methylpent-2-enoate
811-774-1 15790-86-0 Active Intermediate Joint Intermediate use only 23-05-2017 View substance registered dossier
Ethyl (S)-2-hydroxypropionate
211-694-1 687-47-8 Active Full Joint ≥ 10 000 to < 100 000 tonnes 02-12-2022 View substance registered dossier
Ethyl 1,3-dihydro-1,3-dioxo-2H-isoindole-2-carboxylate
245-048-5 22509-74-6 Active Full Joint ≥ 1 to < 10 tonnes 23-06-2022 View substance registered dossier
ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
700-890-7 503614-91-3 Active Full Joint ≥ 1 to < 10 tonnes 26-07-2022 View substance registered dossier
ethyl 1-azabicyclo[2.2.2]oct-2-ene-3-carboxylate
613-021-0 6238-32-0 Active Intermediate Joint Intermediate use only 08-01-2018 View substance registered dossier
ethyl 1-azabicyclo[2.2.2]octane-3-carboxylate
613-022-6 6238-33-1 Active Intermediate Joint Intermediate use only 10-04-2018 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
INFAR S.A. Ctra N-II Km. 680, 6 08389 Palafolls Barcelona Spain Spain Active ethyl (2E)-3-(cyclopropylamino)-2-[(2,4-dichloro-3-methylphenyl)carbonyl]prop-2-enoate 953-808-9 - - View substance registered dossier
CEHTRA Europe S.à.r.l.02 20, Avenue Pasteur L-2310 - Luxembourg Luxembourg Active Ethyl (2E,4Z)-2,4-decadienoate 221-178-8 3025-30-7 2018; 2020 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture ETHYL (2R,3AR,10Z,11AS,12AR,14AR)-2-({7-METHOXY-8-METHYL-2-[4-(PROPAN-2-YL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)-5-METHYL-4,14-DIOXO-2,3,3A,4,5,6,7,8,9,11A,12,13,14,14A-TETRADECAHYDROCYCLOPENTA[C]CYCLOPROPA[G][1,6]DIAZACYCLOTETRADECINE-12A(1H)-CARBOXYLATE 618-843-3 923604-57-3 2021 View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate 430-360-8 84793-24-8 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Cease Manufacture ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate 430-360-8 84793-24-8 2021 View substance registered dossier
INKE, S.A. Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain Spain Active ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate 430-360-8 84793-24-8 2009; 2010; 2017 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate 430-360-8 84793-24-8 - View substance registered dossier
B.I.G. - OR634 Technische Schoolstraat 43A 2440 Geel Belgium Belgium Active ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate 430-360-8 84793-24-8 2011; 2012; 2020 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture ethyl (2S)-2-[(4S)-4-methyl-2,5-dioxo-1,3-oxazolidin-3-yl]-4-phenylbutanoate 430-360-8 84793-24-8 2013 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture ethyl (2S,3S)-3-[(2-chloro-5-fluoro-4-pyrimidinyl)amino]bicyclo[2.2.2]octane-2-carboxylate 821-183-0 1777721-57-9 2022 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture ethyl (2S,3S)-3-aminobicyclo[2.2.2]octane-2-carboxylate monohydrochloride 812-619-0 1626394-43-1 2022 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Cease Manufacture ethyl (2Z)-2-[2-(4-chlorophenyl)hydrazinylidene]-3-(2,6-dichlorophenyl)-3-oxopropanoate 609-702-7 395068-96-9 2018 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active ethyl (3-benzoyl-2,4,6-trimethylbenzoyl)(phenyl)phosphinate 806-801-9 1539267-56-5 2021 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active ethyl (3-cyanomethyl-3,4-dihydro-4-oxophthalazin-1-yl)acetate 429-680-0 122665-86-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active ethyl (3-cyanomethyl-3,4-dihydro-4-oxophthalazin-1-yl)acetate 429-680-0 122665-86-5 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Active Ethyl (3aR,7R,7aR)-2,2-dimethyl-7-[(methylsulfonyl)oxy]-3a,6,7,7a-tetrahydro-1,3-benzodioxole-5-carboxylate 606-548-2 204254-84-2 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Cease Manufacture Ethyl (3aR,7R,7aR)-2,2-dimethyl-7-[(methylsulfonyl)oxy]-3a,6,7,7a-tetrahydro-1,3-benzodioxole-5-carboxylate 606-548-2 204254-84-2 2021 View substance registered dossier
TDeltaS Limited University of Oxford Department of Physiology, Anatomy & Genetics Sherrington Building, Parks Road OX1 3PT Oxford United Kingdom United Kingdom No longer Valid ethyl (3R)-3-hydroxybutanoate 695-003-2 24915-95-5 2021 View substance registered dossier
Borregaard AS Hjalmar Wessels vei 6 1701 Sarpsborg Norway Norway Active ethyl (3R)-4-cyano-3-hydroxybutanoate 430-220-6 141942-85-0 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture ethyl (3R)-4-cyano-3-hydroxybutanoate 430-220-6 141942-85-0 2015 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active ethyl (3R)-4-cyano-3-hydroxybutanoate 430-220-6 141942-85-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active ethyl (3R)-4-cyano-3-hydroxybutanoate 430-220-6 141942-85-0 - View substance registered dossier
Bakhu Pharma Ltd 34 Thursby Road Croft Business Park CH62 3PW Bromborough Wirral United Kingdom United Kingdom No longer Valid ethyl (3R)-4-cyano-3-hydroxybutanoate 430-220-6 141942-85-0 2021 View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany Germany Active Ethyl (3R,4R,5S)-4-acetamido-5-azido-3-(1-ethylpropoxy)cyclohex-1-enecarboxylate 433-320-8 - 2010; 2014; 2019; 2023 View substance registered dossier
S.A. Ajinomoto OmniChem N.V. Industrial Research Park Fleming 1348 Louvain-la-Neuve Belgium Belgium Cease Manufacture Ethyl (3R,4R,5S)-4-acetamido-5-azido-3-(1-ethylpropoxy)cyclohex-1-enecarboxylate 433-320-8 - 2020 View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active Ethyl (3R,4R,5S)-4-acetamido-5-azido-3-(1-ethylpropoxy)cyclohex-1-enecarboxylate 433-320-8 - - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany Germany Active Ethyl (3R,4S,5R)-5-azido-3-(1-ethylpropoxy)-4-hydroxycyclohex-1-ene-1-carboxylate 805-633-3 204254-98-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active Ethyl (4-chlorophenyl)acetate 237-906-2 14062-24-9 - View substance registered dossier
SYNAROME SA 4 rue Charles Tellier 28000 CHARTRES France France Active Ethyl (4-methylphenoxy)acetate 266-554-2 67028-40-4 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active Ethyl (4-methylphenoxy)acetate 266-554-2 67028-40-4 - View substance registered dossier
H. Lundbeck A/S Ottiliavej 7-9 2500 Copenhagen Denmark Denmark Active Ethyl (4S, 5R)-5-(3,4-bis(benzyloxy)phenyl)-4,5-dihydrooxazole-4-carboxylate 955-411-6 1129484-93-0 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active Ethyl (6-bromo-pyridin-2-ylamino)carbonothioylcarbamate 850-733-2 1010120-59-8 2020 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active Ethyl (6-bromo-pyridin-2-ylamino)carbonothioylcarbamate 850-733-2 1010120-59-8 - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active Ethyl (6-bromo-pyridin-2-ylamino)carbonothioylcarbamate 850-733-2 1010120-59-8 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active Ethyl (6-bromo-pyridin-2-ylamino)carbonothioylcarbamate 850-733-2 1010120-59-8 - View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active Ethyl (E)-4-methylpent-2-enoate 811-774-1 15790-86-0 - View substance registered dossier
Galactic Place d'Escanaffles 23 7760 Escanaffles Belgium Belgium Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 - View substance registered dossier
CMC Materials Italia S.r.l. (OR) Via Umbria 4 20098 San Giuliano Milanese Milano Italy Italy Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 2022 View substance registered dossier
Chementors Oy Smart Chemistry Park Raisionkaari 55 21200 Raisio Finland Finland Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 2021 View substance registered dossier
Du Pont de Nemours (Deutschland) GmbH Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany Germany Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 - View substance registered dossier
SIGMA-ALDRICH CHEMIE GMBH Riedstrasse 2 89555 Steinheim Germany Germany Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 2021 View substance registered dossier
SPECIALTY ELECTRONIC MATERIALS UK LIMITED Diamond House Lotus Park Kingsbury Crescent Middx UB7 0DQ Staines Middx United Kingdom United Kingdom No longer Valid Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 2021 View substance registered dossier
Intertek Deutschland GmbH 33 Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany Germany Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 - View substance registered dossier
Purac Biochem bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 2013; 2014; 2015; 2022 View substance registered dossier
Merck Performance Materials GmbH Rheingaustrasse 190-196 65203 Wiesbaden Germany Germany Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 - View substance registered dossier
JSR Micro n.v. Technologielaan 8 3001 Leuven Belgium Belgium Active Ethyl (S)-2-hydroxypropionate 211-694-1 687-47-8 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany Active Ethyl 1,3-dihydro-1,3-dioxo-2H-isoindole-2-carboxylate 245-048-5 22509-74-6 2022 View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 700-890-7 503614-91-3 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 700-890-7 503614-91-3 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 700-890-7 503614-91-3 - View substance registered dossier
Swords Laboratories Unlimited Company Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 700-890-7 503614-91-3 2017; 2020 View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active ethyl 1-azabicyclo[2.2.2]oct-2-ene-3-carboxylate 613-021-0 6238-32-0 - View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active ethyl 1-azabicyclo[2.2.2]octane-3-carboxylate 613-022-6 6238-33-1 - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.