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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 19 January 2021. Database contains 23121 unique substances and contains information from 101751 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

0

Infinite



Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid
205-334-2 138-59-0 null Intermediate Joint Intermediate Use Only 24-05-2020 View substance registered dossier
(3R,4S,5R,6R)-3,4,5-tris[(trimethylsilanyl)oxy]-6-{[(trimethylsilanyl)oxy]methyl}tetrahydro-2H-pyran-2-one
608-732-8 32384-65-9 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(3R,4S,5R,6R)-3,4,5-tris[(trimethylsilanyl)oxy]-6-{[(trimethylsilanyl)oxy]methyl}tetrahydro-2H-pyran-2-one
608-732-8 32384-65-9 Active Intermediate Joint Intermediate use only 31-03-2020 View substance registered dossier
(3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester
433-320-8 - null Intermediate Joint Tonnage Data Confidential 26-05-2020 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
805-486-5 119665-62-2 null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride
607-864-3 26116-57-4 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride
607-864-3 26116-57-4 Active Intermediate Individual Intermediate use only 02-05-2013 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime
603-883-6 134931-01-4 Cease Manufacture Intermediate Individual Cease manufacture 25-10-2012 View substance registered dossier
(3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime
603-883-6 134931-01-4 Active Intermediate Joint Intermediate use only 23-08-2016 View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
918-279-0 - null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one
700-290-5 63968-64-9 Active Intermediate Individual Intermediate use only 15-11-2012 View substance registered dossier
(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
603-817-6 134395-00-9 Active Intermediate Joint Intermediate use only 28-09-2017 View substance registered dossier
(3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE
851-742-4 464207-51-0 null Full Joint 0 - 10 tonnes per annum 13-06-2020 View substance registered dossier
(3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione
603-436-5 13076-17-0 null Full Joint 1 000 - 10 000 tonnes per annum 05-08-2020 View substance registered dossier
(3R,6S)-1-benzyl-6-methylpiperidin-3-amine acetyl-L-leucinate [1:1]
840-203-9 2295746-51-7 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde
812-036-1 1214741-19-1 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
942-823-6 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
810-392-2 171284-84-7 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(3R-)1,1,3-trimethylindan-4-amine
836-285-0 125349-37-3 null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate
228-502-7 6283-74-5 Active Intermediate Joint Intermediate use only 31-08-2018 View substance registered dossier
(3S)-1,3,4-Trihydroxy-2-butanone
443-800-9 - null Full Joint 0 - 10 tonnes per annum 01-10-2020 View substance registered dossier
(3S)-1,3,4-Trihydroxy-2-butanone
443-800-9 - null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(3S)-2-Ethyl-3-hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphtalen-1(2H)-ylidene)ethyl]cyclopentanone
692-111-1 14507-43-8 Active Intermediate Joint Intermediate use only 13-07-2016 View substance registered dossier
(3S)-2-{N-[1-ethoxy-1-oxo-4-phenylbutan-2-yl]-substituted}-heteropolycyclic-3-carboxylic acid hydrochloride
919-408-3 - Active Intermediate Individual Intermediate use only 14-01-2020 View substance registered dossier
(3S)-3,7-Dimethyl-1-octanol
814-059-2 68680-98-8 null Full Joint 0 - 10 tonnes per annum 25-05-2020 View substance registered dossier
(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate
946-529-9 1439355-19-7 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran
619-599-0 915095-94-2 Active Intermediate Joint Intermediate use only 15-04-2020 View substance registered dossier
(3S)-3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one
626-470-2 5405-40-3 Cease Manufacture Full Individual Cease manufacture 05-07-2011 View substance registered dossier
(3S)-3-hydroxypyrrolidin-2-one
676-349-3 34368-52-0 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(3S)-3-thiophen-2-ylsulfanylbutanoic acid
948-811-7 133359-80-5 null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate
950-060-5 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate
603-567-8 132335-47-8 Active Intermediate Individual Intermediate use only 08-10-2009 View substance registered dossier
(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide
430-230-0 136522-17-3 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 Cease Manufacture Intermediate Individual Cease manufacture 29-10-2012 View substance registered dossier
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine
929-011-7 - null Intermediate Joint Intermediate Use Only 30-04-2020 View substance registered dossier
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine
924-787-3 110429-36-2 null Intermediate Joint Intermediate Use Only 25-06-2020 View substance registered dossier
(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone
418-650-2 104872-06-2 null NONS Individual Tonnage Data Confidential 26-05-2020 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 12-07-2013 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 16-05-2018 View substance registered dossier
(3S,5R,8aS)-3-phenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine-5-carbonitrile
634-598-5 106565-71-3 null Intermediate Individual Intermediate Use Only 14-10-2020 View substance registered dossier
(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one
608-748-5 324763-46-4 Active Intermediate Joint Intermediate use only 13-08-2014 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active Full Joint ≥ 0 to < 10 tonnes 16-04-2018 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(3S,6E)-3,7,11-trimethyldodeca-6,10-dienal
810-298-1 194934-66-2 null Full Joint 0 - 10 tonnes per annum 25-09-2020 View substance registered dossier
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
610-965-5 53123-88-9 null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone
444-350-6 133413-70-4 null Intermediate Joint Intermediate Use Only 14-08-2020 View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
224-832-0 4511-42-6 null Full Joint 1 000 - 10 000 tonnes per annum 05-08-2020 View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
224-832-0 4511-42-6 null Full Individual 0 - 10 tonnes per annum 24-05-2020 View substance registered dossier
(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate
430-510-2 - null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium - - (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid 205-334-2 138-59-0 - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany - - (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid 205-334-2 138-59-0 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany - - (3R,4S,5R)-3,4,5-trihydroxycyclohex-1-enecarboxylic acid 205-334-2 138-59-0 - View substance registered dossier
[Confidential] [Confidential] - - (3R,4S,5R,6R)-3,4,5-tris[(trimethylsilanyl)oxy]-6-{[(trimethylsilanyl)oxy]methyl}tetrahydro-2H-pyran-2-one 608-732-8 32384-65-9 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (3R,4S,5R,6R)-3,4,5-tris[(trimethylsilanyl)oxy]-6-{[(trimethylsilanyl)oxy]methyl}tetrahydro-2H-pyran-2-one 608-732-8 32384-65-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (3R,4S,5R,6R)-3,4,5-tris[(trimethylsilanyl)oxy]-6-{[(trimethylsilanyl)oxy]methyl}tetrahydro-2H-pyran-2-one 608-732-8 32384-65-9 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (3R,4S,5R,6R)-3,4,5-tris[(trimethylsilanyl)oxy]-6-{[(trimethylsilanyl)oxy]methyl}tetrahydro-2H-pyran-2-one 608-732-8 32384-65-9 - View substance registered dossier
Roche Pharma AG (1) Emil-Barell-Strasse 1 79639 Grenzach-Wyhlen Germany - - (3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 433-320-8 - - View substance registered dossier
Dynamit Nobel GmbH Explosivstoff- und Systemtechnik Kalkstrasse 218 51377 Leverkusen Germany - - (3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 433-320-8 - - View substance registered dossier
S.A. Ajinomoto OmniChem N.V. Industrial Research Park Fleming 1348 Louvain-la-Neuve Belgium - - (3R,4S,5S)-5-azido-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-enecarboxylic acid ethyl ester 433-320-8 - - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain - - (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-6-methyl-3-trimethylsilyloxyoxan-2-yl]oxy-10-(2-ethoxypropan-2-yloxyimino)-14-ethyl-12,13-dihydroxy-7-methoxy-4-[(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-trimethylsilyloxyoxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one 805-486-5 119665-62-2 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia - - (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride 607-864-3 26116-57-4 - View substance registered dossier
Sandoz Industrial Products SA Ctra. Granollers - Cardedeu C-251, Km 4 08520 Les Franqueses del Vallés Spain Spain Active (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one hydrochloride 607-864-3 26116-57-4 - View substance registered dossier
[Confidential] - - - (3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime 603-883-6 134931-01-4 - View substance registered dossier
[Confidential] - - - (3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime 603-883-6 134931-01-4 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain - - (3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 918-279-0 - - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one 700-290-5 63968-64-9 2009; 2010; 2012 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate 603-817-6 134395-00-9 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France - - (3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE 851-742-4 464207-51-0 - View substance registered dossier
PURAC Biochem Arkelsedijk 46 4206AC Gorinchem Netherlands - - (3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione 603-436-5 13076-17-0 - View substance registered dossier
Total Corbion PLA bv Arkelsedijk 46 4206AC Gorinchem Netherlands - - (3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione 603-436-5 13076-17-0 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany - - (3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione 603-436-5 13076-17-0 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (3R,6S)-1-benzyl-6-methylpiperidin-3-amine acetyl-L-leucinate [1:1] 840-203-9 2295746-51-7 2020 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France - - (3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde 812-036-1 1214741-19-1 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France - - (3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione 942-823-6 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France - - (3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione 810-392-2 171284-84-7 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany - - (3R-)1,1,3-trimethylindan-4-amine 836-285-0 125349-37-3 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate 228-502-7 6283-74-5 - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate 228-502-7 6283-74-5 2018 View substance registered dossier
Givaudan France Fragrances SA 19-23, Voie des Bans, B.P. 98 95102 Argenteuil France - - (3S)-1,3,4-Trihydroxy-2-butanone 443-800-9 - - View substance registered dossier
SpecChem GmbH Robert Bosch Strasse 29a 88131 Lindau Germany - - (3S)-1,3,4-Trihydroxy-2-butanone 443-800-9 - - View substance registered dossier
- - - - (3S)-1,3,4-Trihydroxy-2-butanone 443-800-9 - - View substance registered dossier
DSM Nutritional Products GmbH Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany - - (3S)-1,3,4-Trihydroxy-2-butanone 443-800-9 - - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (3S)-2-Ethyl-3-hydroxy-2-[(2E)-2-(6-methoxy-3,4-dihydronaphtalen-1(2H)-ylidene)ethyl]cyclopentanone 692-111-1 14507-43-8 - View substance registered dossier
[Confidential] - - - (3S)-2-{N-[1-ethoxy-1-oxo-4-phenylbutan-2-yl]-substituted}-heteropolycyclic-3-carboxylic acid hydrochloride 919-408-3 - - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France - - (3S)-3,7-Dimethyl-1-octanol 814-059-2 68680-98-8 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain - - (3S)-3,7-dimethylocta-1,6-dien-1-yl acetate 946-529-9 1439355-19-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran 619-599-0 915095-94-2 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran 619-599-0 915095-94-2 2019 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran 619-599-0 915095-94-2 2019 View substance registered dossier
TÜV SÜD Industrie Service GmbH IS-USR-MUC Westendstr. 199 80686 Munich Germany Germany Cease Manufacture (3S)-3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one 626-470-2 5405-40-3 2015 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany - - (3S)-3-hydroxypyrrolidin-2-one 676-349-3 34368-52-0 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain - - (3S)-3-thiophen-2-ylsulfanylbutanoic acid 948-811-7 133359-80-5 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France - - (3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate 950-060-5 - - View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active (3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate 603-567-8 132335-47-8 2009 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland - - (3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide 430-230-0 136522-17-3 - View substance registered dossier
- - - - (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 - View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary - - (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine 929-011-7 - - View substance registered dossier
CHEMI S.p.A. Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy - - (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine 924-787-3 110429-36-2 - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland - - (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-methylpiperidine 924-787-3 110429-36-2 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria - - (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 - View substance registered dossier
- - - - (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 - View substance registered dossier
[Confidential] - - - (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - 2011; 2015 View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Germany - - (3S,5R,8aS)-3-phenylhexahydro-5H-[1,3]oxazolo[3,2-a]pyridine-5-carbonitrile 634-598-5 106565-71-3 - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy IE Ringaskiddy Cork Ireland Ireland Active (3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one 608-748-5 324763-46-4 2014 View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom Active (3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one 608-748-5 324763-46-4 2014 View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - 2018 View substance registered dossier
- - - - (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - - View substance registered dossier
TAKASAGO TEPL-Importer 12 rue Torricelli 75017 Paris France - - (3S,6E)-3,7,11-trimethyldodeca-6,10-dienal 810-298-1 194934-66-2 - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France - - (3S,6E)-3,7,11-trimethyldodeca-6,10-dienal 810-298-1 194934-66-2 - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia - - (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone 610-965-5 53123-88-9 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany - - (3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone 444-350-6 133413-70-4 - View substance registered dossier
Bayer Animal Health GmbH Alfred Nobel Straße 50 40789 Monheim Germany - - (3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone 444-350-6 133413-70-4 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany - - (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
PURAC Biochem Arkelsedijk 46 4206AC Gorinchem Netherlands - - (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
Total Corbion PLA bv Arkelsedijk 46 4206AC Gorinchem Netherlands - - (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
Santrol Europe ApS Aagade 103 Pjedsted 7000 Fredericia Denmark - - (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
- - - - (3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate 430-510-2 - - View substance registered dossier

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