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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

REACH registered substance data was upgraded on 9th November. The per substance REACH registration status is being calculated and will be made available as soon as possible.

We apologise for the inconvenience in the meantime.

The result of the search ‘Substance has nanoform’ returns all factsheets containing data related to nanomaterials. However, this does not mean that a registration covering nanoforms of the substance has been submitted in line with the revised annexes of REACH by all the registrants concerned. Note that since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA using IUCLID version 6.4 (released on 30 October 2019).

Last updated 16 January 2021. Database contains 23121 unique substances and contains information from 101750 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
(1S,4R,4aS,9aR)-4,4a,9,9a-tetrahydro-1H-1,4-methanofluorene
700-736-9 - null Full Individual 100 - 1 000 tonnes per annum 22-07-2020 View substance registered dossier
(1α5α6α)-6-nitro-3-benzyl-3-azabicyclo[3,1,0]hexane methanesulfonate salt
426-740-8 - null NONS Individual Tonnage Data Confidential 25-08-2020 View substance registered dossier
(2,3,5,6-tetrafluoro-4-methylphenyl)methanol
453-520-9 - Active NONS Individual Tonnage data confidential 08-12-2020 View substance registered dossier
(2,4,6-trioxo-2H,4H,6H-1,3,5-triazine-1,3,5-triyl)triethylene tri(acetoacetate)
403-570-2 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active Full Joint ≥ 10 to < 100 tonnes 12-04-2019 View substance registered dossier
(2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol
437-760-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate
442-300-8 - Active Full Joint ≥ 100 to < 1 000 tonnes 24-11-2020 View substance registered dossier
(2-benzyl-acryloylamino)-acetic acid benzyl ester
921-619-0 - null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2-butoxyethoxy)acetic acid
451-650-0 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone
464-300-7 - Active Intermediate Individual Intermediate use only 17-12-2010 View substance registered dossier
(2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone
464-300-7 - Active Intermediate Joint Intermediate use only 22-11-2010 View substance registered dossier
(2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid
426-680-2 - Active Intermediate Individual Intermediate use only 28-11-2011 View substance registered dossier
(2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid
426-680-2 - null NA Individual Intermediate Use Only 25-08-2020 View substance registered dossier
(2E)-2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methylene]-5,6-dimethoxyindan-1-one hydrochloride (1:1)
940-983-1 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2E)-3-(4-methoxyphenyl)-2-methylprop-2-enal
945-034-5 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2E,4E)-2-methyl-5-phenyl-penta-2,4-dienal
919-772-3 - null Intermediate Individual Intermediate Use Only 24-05-2020 View substance registered dossier
(2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid
951-764-5 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt
944-007-5 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2R)-6-fluoro-2-(oxiran-2-yl)chromane
930-890-4 - Active Full Joint ≥ 1 to < 10 tonnes 03-06-2019 View substance registered dossier
(2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1)
947-841-8 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate
427-100-0 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(2R*,3S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethylnaphthalene; reaction mass of: (1R*,2S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethylnaphthalene
425-570-1 - null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1)
920-610-9 - Active Intermediate Joint Intermediate use only 12-04-2017 View substance registered dossier
(2R,3R)-2,3-Dihydroxybutanedioic acid--(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1)
947-840-2 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid
948-743-8 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate
927-721-1 - Active Intermediate Joint Intermediate use only 19-06-2020 View substance registered dossier
(2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride
928-729-8 - null Intermediate Joint Intermediate Use Only 25-03-2020 View substance registered dossier
(2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate
917-473-2 - null Intermediate Joint Intermediate Use Only 25-03-2020 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Full Joint ≥ 10 to < 100 tonnes 15-02-2012 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - Active Full Joint ≥ 10 to < 100 tonnes 16-05-2017 View substance registered dossier
(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
431-620-3 - null Intermediate Joint Intermediate Use Only 13-06-2020 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Cease Manufacture Intermediate Individual Cease manufacture 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Individual Intermediate use only 22-11-2011 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - null Intermediate Joint Intermediate Use Only 23-05-2020 View substance registered dossier
(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid
406-310-6 - Active Intermediate Joint Intermediate use only 26-02-2020 View substance registered dossier
(2S)-2-amino-3-(4-hydroxyphenyl)propanal semicarbazone hydrochloride (1:1)
940-825-1 - null Intermediate Individual Intermediate Use Only 25-05-2020 View substance registered dossier
(2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone
477-290-4 - null NONS Individual Tonnage Data Confidential 02-04-2020 View substance registered dossier
(2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
475-290-9 - Active Full Individual ≥ 1 to < 10 tonnes 26-02-2010 View substance registered dossier
(2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
475-290-9 - null NONS Individual Tonnage Data Confidential 30-03-2020 View substance registered dossier
(2S)-6-fluoro-2-(oxiran-2-yl)chromane
930-889-9 - Active Full Joint ≥ 1 to < 10 tonnes 03-06-2019 View substance registered dossier
(2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1)
947-432-4 - null Intermediate Joint Intermediate Use Only 08-09-2020 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - Cease Manufacture Intermediate Individual Cease manufacture 05-11-2012 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - Cease Manufacture Intermediate Individual Cease manufacture 19-10-2012 View substance registered dossier
(2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride
478-270-8 - Cease Manufacture Intermediate Joint Cease manufacture 04-09-2012 View substance registered dossier
(2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate
938-481-2 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester
411-020-8 - Active Intermediate Joint Intermediate use only 09-12-2013 View substance registered dossier
(2S,4R)-1-hexadecanoyl-4-hydroxy-pyrrolidine-2-carboxylic acid
944-347-4 - null Intermediate Joint Intermediate Use Only 25-05-2020 View substance registered dossier
(2S-cis)-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2.]octan-3-amine (1-R camphor-10-sulfonate)
444-810-6 - Active Full Joint ≥ 1 to < 10 tonnes 17-07-2019 View substance registered dossier
(2S-cis)-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2.]octan-3-amine (1-R camphor-10-sulfonate)
444-810-6 - Active Intermediate Individual Intermediate use only 02-10-2014 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Covance Clinical Development SA 163 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain - - (1S,4R,4aS,9aR)-4,4a,9,9a-tetrahydro-1H-1,4-methanofluorene 700-736-9 - - View substance registered dossier
- - - - (1α5α6α)-6-nitro-3-benzyl-3-azabicyclo[3,1,0]hexane methanesulfonate salt 426-740-8 - - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom Active (2,3,5,6-tetrafluoro-4-methylphenyl)methanol 453-520-9 - 2013; 2020 View substance registered dossier
- - - - (2,4,6-trioxo-2H,4H,6H-1,3,5-triazine-1,3,5-triyl)triethylene tri(acetoacetate) 403-570-2 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - 2011; 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2,5-dimethyl-2,3-dihydro-1H-inden-2-yl)methanol 437-760-1 - - View substance registered dossier
IGM Resins Ltd c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom United Kingdom Active (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - - View substance registered dossier
IGM Resins Italia S.r.l Via Vincenzo Monti, 8 20123 Milano Italy Italy Active (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2014; 2016; 2017 View substance registered dossier
BASF Performance Products France SA 49, Avenue Georges Pompidou 92593 Levallois-Perret Cedex France France Cease Manufacture (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - 2015 View substance registered dossier
WSP UK Ltd. WSP HOUSE 70 CHANCERY LANE WC2A 1AF LONDON United Kingdom United Kingdom Active (2-(2-hydroxyethoxy)ethyl) oxo(phenyl)acetate; reaction mass of: 2-(2-((oxo(phenyl)acetyl)oxy)ethoxy)ethyl oxo(phenyl)acetate 442-300-8 - - View substance registered dossier
EXPANSIA Route d'Avignon BP 6 30390 ARAMON France - - (2-benzyl-acryloylamino)-acetic acid benzyl ester 921-619-0 - - View substance registered dossier
Kao Chemicals GmbH Kupferstrasse 1 46446 Emmerich Northrhine-Westfalia Germany - - (2-butoxyethoxy)acetic acid 451-650-0 - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom Active (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - - View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Cease Manufacture (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)methanone 464-300-7 - 2010 View substance registered dossier
Euticals SAS ZI de Laville 47240 BON-ENCONTRE France France Active (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid 426-680-2 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy - - (2-formamido-1,3-thiazol-4-yl)(oxo)acetic acid 426-680-2 - - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia - - (2E)-2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methylene]-5,6-dimethoxyindan-1-one hydrochloride (1:1) 940-983-1 - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain - - (2E)-3-(4-methoxyphenyl)-2-methylprop-2-enal 945-034-5 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany - - (2E,4E)-2-methyl-5-phenyl-penta-2,4-dienal 919-772-3 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France - - (2R)-2-(2,5-difluorophenyl)pyrrolidine, (2R,3R)-2,3-bis[(4-methoxybenzoyl)oxy]butanedioic acid 951-764-5 - - View substance registered dossier
Clarochem Ireland Ltd damastown mulhuddart dn 15 dublin Ireland - - (2R)-2-(3-Benzoylphenyl)propanoic acid, 1-Deoxy-1-(octylamino)-D-glucitol salt 944-007-5 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2R)-6-fluoro-2-(oxiran-2-yl)chromane 930-890-4 - 2019 View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany - - (2R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide - (2R,3R)-2,3-dihydroxysuccinic acid - propan-2-ol (2:1:1) 947-841-8 - - View substance registered dossier
Pfizer Ltd Ramsgate Road (IPC 979) CT13 9NJ Sandwich Kent United Kingdom - - (2R*,3S*)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate 427-100-0 - - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France - - (2R*,3S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethylnaphthalene; reaction mass of: (1R*,2S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethylnaphthalene 425-570-1 - - View substance registered dossier
- - - - (2R*,3S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethylnaphthalene; reaction mass of: (1R*,2S*)-2-acetyl-1,2,3,4,5,6,7,8-octahydro-1,2,8,8-tetramethylnaphthalene 425-570-1 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (2R,3R)-2,3-bis(acetyloxy)butanedioic acid - 3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (1:1) 920-610-9 - - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany - - (2R,3R)-2,3-Dihydroxybutanedioic acid--(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide (1/1) 947-840-2 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy - - (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol [(1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulfonic acid 948-743-8 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - 2013 View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-12,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulfonate 927-721-1 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland - - (2RS, 3SR)-3-(6-chloro-5-fluoro-4-pyrimidinyl)-2-(2,4- difluorphenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride 928-729-8 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland - - (2RS,3SR)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol (1R)-10-camphorsulphonate 917-473-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2011 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - 2009; 2010; 2017 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy - - (2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid 431-620-3 - - View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
TAMARANG, S.A. Balmes, 84, 4-2 08008 Barcelona Barcelona Spain Spain Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2012 View substance registered dossier
ROLABO OUTSOURCING, S.L. Polígono Industrial Malpica. Calle J, nº 3-4 50016 Zaragoza Zaragoza Spain Spain Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain - - (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary - - (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2010; 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
B.I.G. - OR634 Technische Schoolstraat 43A 2440 Geel Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2011; 2012; 2014; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2010; 2012 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Cease Manufacture (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - 2014 View substance registered dossier
MAPIC Europe NV EXCELSIORLAAN 83 1930 ZAVENTEM Belgium Belgium Active (2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoic acid 406-310-6 - - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy - - (2S)-2-amino-3-(4-hydroxyphenyl)propanal semicarbazone hydrochloride (1:1) 940-825-1 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium - - (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Gruenenthal GmbH Zieglerstrasse 6 52078 Aachen Germany - - (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Első Vegyi Industria ZRt. Kartács utca 6. H-1139 BUDAPEST Hungary - - (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanonone 477-290-4 - - View substance registered dossier
Evonik Rexim S.A.S. 33, Rue de Verdun 80400 Ham France France Active (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - - View substance registered dossier
- - - - (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 475-290-9 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (2S)-6-fluoro-2-(oxiran-2-yl)chromane 930-889-9 - 2019 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland - - (2S,3S)-2,3-Bis[(4-methylbenzoyl)oxy]butanedioic acid — methyl {(4S)-8-fluoro-2-[4-(3methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4yl}acetate — ethyl acetate (1:1:1) 947-432-4 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2019 View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom Cease Manufacture (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2019 View substance registered dossier
Envigo Consulting Limited Woolley Road Alconbury PE28 4HS Huntingdon Cambridgeshire United Kingdom United Kingdom Cease Manufacture (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyhexanamide hydrochloride 478-270-8 - 2019 View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy - - (2S,3S,5S)-5-amino-2-(dibenzylamino)-1,6-diphenylhexan-3-ol succinate 938-481-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (2S,4R)-1-benzoyl-4-hydroxy-pyrrolydin-2-carboxylic acid methyl ester 411-020-8 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany - - (2S,4R)-1-hexadecanoyl-4-hydroxy-pyrrolidine-2-carboxylic acid 944-347-4 - - View substance registered dossier
Zoetis Belgium S.A. Rue Laid Burniat, 1 1348 Louvain-La-Neuve Belgium Belgium Active (2S-cis)-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2.]octan-3-amine (1-R camphor-10-sulfonate) 444-810-6 - - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (2S-cis)-(diphenylmethyl)-N-(phenylmethyl)-1-azabicyclo[2.2.2.]octan-3-amine (1-R camphor-10-sulfonate) 444-810-6 - 2014 View substance registered dossier

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