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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 13 April 2021. Database contains 25848 unique substances and contains information from 100151 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
(1R)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
807-025-3 1315508-94-1 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
(1R)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
807-026-9 1315508-93-0 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
(1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride
700-425-8 521284-22-0 Active Full Joint Tonnage data confidential 30-03-2016 View substance registered dossier
(1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol
252-744-2 35836-73-8 Active Full Joint ≥ 10 to < 100 tonnes 11-05-2018 View substance registered dossier
(1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid
252-817-9 35963-20-3 Active Intermediate Joint Intermediate use only 07-01-2020 View substance registered dossier
(1R)-cyclohex-3-ene-1-carboxylic acid
634-674-8 5709-98-8 Active Intermediate Joint Intermediate use only 11-09-2017 View substance registered dossier
(1R)cyclohex-3-enecarboxylic acid (1S)-1-phenylethylamine
814-700-6 67976-81-2 Active Intermediate Joint Intermediate use only 03-10-2017 View substance registered dossier
(1R*,6S*)-6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium monooxalate
700-689-4 41524-32-7 Active Intermediate Individual Intermediate use only 21-09-2011 View substance registered dossier
(1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride
609-015-2 3464-71-9 Active Intermediate Joint Intermediate use only 12-03-2018 View substance registered dossier
(1R, 4R, 5S) 4-hydroxy-6,6-dimethyl-3-Oxabicyclo[3.1.0]hexan-2-one
619-753-7 73611-02-6 Active Intermediate Joint Intermediate use only 12-05-2014 View substance registered dossier
(1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate
607-316-3 240806-31-9 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile
608-856-2 33300-19-5 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,2R)-1,2-Cyclohexanedimethanol
692-053-7 65376-05-8 Active Intermediate Joint Intermediate use only 24-10-2018 View substance registered dossier
(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate
445-910-2 - Active Full Joint ≥ 1 to < 10 tonnes 14-10-2016 View substance registered dossier
(1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride
943-460-6 - Active Intermediate Joint Intermediate use only 16-06-2020 View substance registered dossier
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide
600-115-1 1006376-62-0 Active Intermediate Individual Intermediate use only 29-01-2018 View substance registered dossier
(1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid
609-759-8 39961-95-0 Active Intermediate Joint Intermediate use only 29-01-2018 View substance registered dossier
(1R,2R,3S,4S)-1-(1,1,3,3-tetraoxido-1,3-dithian-2-yl)pentane-1,2,3,4-tetrol
936-126-6 1352707-53-9 Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
(1R,2R,3S,4S)-1-(1,3-dithian-2-yl)pentane-1,2,3,4-tetrol
936-125-0 1352707-52-8 Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
(1R,2R,4S)- 1,3,3-trimethylbicyclo(2.2.1)heptan-2-ol
606-948-7 2217-02-9 Active Full Joint ≥ 10 to < 100 tonnes 20-07-2020 View substance registered dossier
(1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate
807-751-0 4057-31-2 Active Full Joint ≥ 10 to < 100 tonnes 07-05-2018 View substance registered dossier
(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropanaminium 4-methylbenzenesulfonate
801-606-5 1028252-16-5 Active Intermediate Joint Intermediate use only 11-05-2017 View substance registered dossier
(1R,2S)-1-phenyl-2-pyrrolidin-1-yl-propan-1-ol;hydrochloride
606-696-8 210558-66-0 Active Intermediate Joint Intermediate use only 06-09-2017 View substance registered dossier
(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine
700-140-9 752984-24-0 Active Intermediate Joint Intermediate use only 19-02-2020 View substance registered dossier
(1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine
700-140-9 752984-24-0 Active Intermediate Individual Intermediate use only 18-05-2011 View substance registered dossier
(1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate
816-798-6 1352613-22-9 Active Intermediate Joint Intermediate use only 14-11-2017 View substance registered dossier
(1R,2S)-cyclohexane-1,2-diamine; sulfuric acid
613-794-4 65433-80-9 Active Intermediate Joint Intermediate use only 13-04-2018 View substance registered dossier
(1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol
601-595-5 119302-20-4 Active Full Individual ≥ 1 to < 10 tonnes 09-07-2015 View substance registered dossier
(1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol
601-595-5 119302-20-4 Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
(1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane)
443-460-1 - Active Full Joint ≥ 1 tonnes 05-07-2012 View substance registered dossier
(1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
821-184-6 1777721-60-4 Active Full Joint ≥ 0 to < 10 tonnes 28-02-2019 View substance registered dossier
(1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid
821-185-1 1777721-63-7 Active Full Joint ≥ 1 to < 10 tonnes 28-02-2019 View substance registered dossier
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
604-569-1 147126-62-3 Active Intermediate Individual Intermediate use only 14-12-2012 View substance registered dossier
(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate
604-569-1 147126-62-3 Cease Manufacture Intermediate Joint Cease manufacture 13-08-2014 View substance registered dossier
(1R,2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboxamide
700-232-9 68489-09-8 Active Full Joint ≥ 1 to < 10 tonnes 25-05-2016 View substance registered dossier
(1R,2S,5R)-5-methyl-2-(propan-2-yl)-N-[2-(pyridin-2-yl)ethyl]cyclohexanecarboxamide
700-097-6 847565-09-7 Active Full Individual ≥ 0 to < 10 tonnes 01-03-2011 View substance registered dossier
(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl (ethylamino)(oxo)acetate
700-185-4 1122460-01-8 Active Full Joint ≥ 1 to < 10 tonnes 17-12-2012 View substance registered dossier
(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
939-499-3 - Active Intermediate Individual Intermediate use only 24-05-2013 View substance registered dossier
(1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3- yl)piperazin-1-yl]methyl}-cyclohexyl]methyl}-4- azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione
696-042-8 367514-87-2 Active Intermediate Joint Intermediate use only 25-10-2018 View substance registered dossier
(1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate
689-794-3 171489-59-1 Active Intermediate Joint Intermediate use only 09-10-2020 View substance registered dossier
(1R,3S)-2,2-Dimethyl-3-(2-oxopropyl)cyclopropanecarboxylic acid
615-083-4 70223-33-5 Active Intermediate Joint Intermediate use only 30-04-2013 View substance registered dossier
(1R,3S)-3-((1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarbonyl chloride
614-284-4 68127-98-0 No longer Valid Intermediate Individual No longer valid 26-11-2020 View substance registered dossier
(1R,3S)-3-aminocyclopentan-1-ol benzoate
946-279-0 1846582-38-4 Active Intermediate Joint Intermediate use only 20-06-2018 View substance registered dossier
(1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
625-288-0 291775-59-2 Active Intermediate Individual Intermediate use only 20-01-2015 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active NONS Joint Tonnage data confidential 07-10-2010 View substance registered dossier
(1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane
447-620-1 - Active Intermediate Joint Intermediate use only 13-07-2018 View substance registered dossier
(1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane
427-580-1 211299-54-6 Active Full Joint ≥ 10 tonnes 09-07-2020 View substance registered dossier
(1R,4aS,8R,8aS)-2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a-octahydronaphthalen-1-ol
434-960-0 103614-86-4 Active NONS Joint Tonnage data confidential 10-01-2011 View substance registered dossier
(1R,4R)-4-methoxy-2,2,7,7-tetramethyltricyclo(6.2.1.0(1,6))undec-5-ene
444-480-3 - Active NONS Individual Tonnage data confidential 07-04-2011 View substance registered dossier
(1R,4R,5S)- 4-(1,1-Dichloro-2,2,2-trifluoroethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one
606-114-2 187592-70-7 Active Intermediate Joint Intermediate use only 16-09-2013 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-025-3 1315508-94-1 2017 View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (1R)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-025-3 1315508-94-1 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (1R)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-026-9 1315508-93-0 2016 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-026-9 1315508-93-0 2017 View substance registered dossier
[Confidential] - - - (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride 700-425-8 521284-22-0 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol 252-744-2 35836-73-8 2018 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol 252-744-2 35836-73-8 2017 View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 2018 View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 2018 View substance registered dossier
Aceto France 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
PORTA s.r.o. Zelený pruh 99 14002 Praha 4 Czech Republic Czech Republic Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)-cyclohex-3-ene-1-carboxylic acid 634-674-8 5709-98-8 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)cyclohex-3-enecarboxylic acid (1S)-1-phenylethylamine 814-700-6 67976-81-2 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (1R*,6S*)-6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium monooxalate 700-689-4 41524-32-7 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride 609-015-2 3464-71-9 - View substance registered dossier
[Confidential] - - - (1R, 4R, 5S) 4-hydroxy-6,6-dimethyl-3-Oxabicyclo[3.1.0]hexan-2-one 619-753-7 73611-02-6 - View substance registered dossier
CRYSTAL PHARMA SAU Parque Tecnológico, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate 607-316-3 240806-31-9 2018 View substance registered dossier
CRYSTAL PHARMA SAU Parque Tecnológico, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile 608-856-2 33300-19-5 2018 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (1R,2R)-1,2-Cyclohexanedimethanol 692-053-7 65376-05-8 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 - 2010; 2011; 2012; 2014 View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 - 2010; 2012; 2014; 2016 View substance registered dossier
AbbVie Ireland NL B.V. Manorhamilton Road none Sligo Ireland Ireland Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - 2020 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide 600-115-1 1006376-62-0 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid 609-759-8 39961-95-0 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (1R,2R,3S,4S)-1-(1,1,3,3-tetraoxido-1,3-dithian-2-yl)pentane-1,2,3,4-tetrol 936-126-6 1352707-53-9 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (1R,2R,3S,4S)-1-(1,3-dithian-2-yl)pentane-1,2,3,4-tetrol 936-125-0 1352707-52-8 - View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (1R,2R,4S)- 1,3,3-trimethylbicyclo(2.2.1)heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
LLUCH ESSENCE, S.L. Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain Spain Active (1R,2R,4S)- 1,3,3-trimethylbicyclo(2.2.1)heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,2R,4S)- 1,3,3-trimethylbicyclo(2.2.1)heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,2R,4S)- 1,3,3-trimethylbicyclo(2.2.1)heptan-2-ol 606-948-7 2217-02-9 2018 View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,2R,4S)- 1,3,3-trimethylbicyclo(2.2.1)heptan-2-ol 606-948-7 2217-02-9 2019 View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate 807-751-0 4057-31-2 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate 807-751-0 4057-31-2 - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropanaminium 4-methylbenzenesulfonate 801-606-5 1028252-16-5 - View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active (1R,2S)-1-phenyl-2-pyrrolidin-1-yl-propan-1-ol;hydrochloride 606-696-8 210558-66-0 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 752984-24-0 2011; 2019; 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (1R,2S)-2,6-dimethyl-2,3-dihydro-1H-inden-1-amine 700-140-9 752984-24-0 2011 View substance registered dossier
a.c.r.a.f. s.p.a. via guardapasso 1 04011 aprilia Italy Italy Active (1R,2S)-2-ethenyl-1-(ethoxycarbonyl)cyclopropanaminium (2S)-2-[(4-chlorobenzoyl)oxy]propanoate 816-798-6 1352613-22-9 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R,2S)-cyclohexane-1,2-diamine; sulfuric acid 613-794-4 65433-80-9 - View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Active (1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol 601-595-5 119302-20-4 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol 601-595-5 119302-20-4 - View substance registered dossier
FARMHISPANIA S.A. Passeig del Riu Besós, 9-10 08160 Montmeló Barcelona Spain Spain Active (1R,2S,10R,11S,15S)-2,15-dimethyl-4-(morpholin-4-yl)-13-(pyrrolidin-1-yl)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecane-5,14-diol 601-595-5 119302-20-4 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - 2012 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,2S,2'S,4R)-1,7,7-Trimethylbicyclo (2.2.1)heptane-2-spiro-4'-(2'-isopropyl-1',3'-dioxane) 443-460-1 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (1R,2S,3S,4R)-3-((2-chloro-5-fluoropyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid 821-184-6 1777721-60-4 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (1R,2S,3S,4R)-3-((5-fluoro-2-(5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)bicyclo[2.2.2]octane-2-carboxylic acid 821-185-1 1777721-63-7 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate 604-569-1 147126-62-3 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Cease Manufacture (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylate 604-569-1 147126-62-3 2021 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,2S,5R)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexanecarboxamide 700-232-9 68489-09-8 - View substance registered dossier
Only representative (No publishable name) - - Active (1R,2S,5R)-5-methyl-2-(propan-2-yl)-N-[2-(pyridin-2-yl)ethyl]cyclohexanecarboxamide 700-097-6 847565-09-7 2009; 2011 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl (ethylamino)(oxo)acetate 700-185-4 1122460-01-8 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 939-499-3 - - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (1R,2S,6R,7S)-4-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3- yl)piperazin-1-yl]methyl}-cyclohexyl]methyl}-4- azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione 696-042-8 367514-87-2 - View substance registered dossier
POLPHARMA 19 Pelplińska 83-200 Starogard Gdański Poland Poland Active (1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate 689-794-3 171489-59-1 - View substance registered dossier
[Confidential] - - - (1R,3S)-2,2-Dimethyl-3-(2-oxopropyl)cyclopropanecarboxylic acid 615-083-4 70223-33-5 - View substance registered dossier
Syngenta Ltd Jealott’s Hill International Research Centre RG42 6EY Bracknell Berkshire United Kingdom United Kingdom No longer Valid (1R,3S)-3-((1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl)-2,2-dimethylcyclopropanecarbonyl chloride 614-284-4 68127-98-0 2021 View substance registered dossier
Euticals SAS ZI de Laville 47240 BON-ENCONTRE France France Active (1R,3S)-3-aminocyclopentan-1-ol benzoate 946-279-0 1846582-38-4 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,3S)-3-aminocyclopentan-1-ol benzoate 946-279-0 1846582-38-4 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,3S,4S)-2-(tert-butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 625-288-0 291775-59-2 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
- - - - (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (1R,3s,5S)-8-benzyl-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane 447-620-1 - 2018 View substance registered dossier
Symrise Ltd. Fieldhouse Lane SL7 1TB Marlow Bucks Buckinghamshire United Kingdom United Kingdom Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 211299-54-6 2016 View substance registered dossier
Symrise Ibérica, S.L. Polígono Industrial Can Volart Ctra. C-17 Km. 15 08150 Parets de Valles (Barcelona) Spain Spain Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 211299-54-6 2019 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 211299-54-6 2010; 2015 View substance registered dossier
Symrise A4 Mühlenfeldstr. 1 37603 Holzminden Germany Germany Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 211299-54-6 2019 View substance registered dossier
[Confidential] - - - (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 211299-54-6 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active (1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane 427-580-1 211299-54-6 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1R,4aS,8R,8aS)-2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a-octahydronaphthalen-1-ol 434-960-0 103614-86-4 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (1R,4aS,8R,8aS)-2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a-octahydronaphthalen-1-ol 434-960-0 103614-86-4 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,4R)-4-methoxy-2,2,7,7-tetramethyltricyclo(6.2.1.0(1,6))undec-5-ene 444-480-3 - 2011 View substance registered dossier
[Confidential] - - - (1R,4R,5S)- 4-(1,1-Dichloro-2,2,2-trifluoroethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one 606-114-2 187592-70-7 - View substance registered dossier

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