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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The REACH Registered substance portal was updated on 9th November 2020; the REACH registered factsheets were further updated on 21st December 2020. Details of the improvements can be found at Dissemination Platform Updates. Reprocessing the entire dataset is ongoing since 21 December 2020. ECHA is making all possible efforts to make the improvements and additional data visible with the shortest delay.
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 17 June 2021. Database contains 23308 unique substances and contains information from 103805 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
2-alkoyloxyethyl hydrogen maleate, where alkoyl represents (by weight) 70 to 85% unsaturated octadecoyl, 0.5 to 10% saturated octadecoyl, and 2 to 18% saturated hexadecoyl
417-960-5 - Active NONS Individual Tonnage data confidential 01-08-2013 View substance registered dossier
2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylene]propanehydrazide hydrochloride (1:1)
940-411-0 1353749-74-2 Active Intermediate Individual Intermediate use only 03-05-2018 View substance registered dossier
2-Amino-4,5-dimethyl-thiophene-3-carbonitrile
610-309-8 4651-94-9 Active Intermediate Individual Intermediate use only 02-10-2012 View substance registered dossier
2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester
829-017-9 1034975-35-3 Active Intermediate Individual Intermediate use only 30-05-2019 View substance registered dossier
2-amino-4-bromo-5-chlorobenzoic acid
424-700-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine
415-500-8 145963-84-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Amino-4-methylsulfonylaminomethylbenzoic acid methylester
480-220-5 393509-78-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-5-(2-hydroxyethyl)-6-methyl-4(3H)-pyrimidinone
814-705-3 6940-45-0 Active Full Individual ≥ 0 to < 10 tonnes 27-05-2018 View substance registered dossier
2-amino-5-bromopyridin-3-yl 4-methylbenzenesulfonate
943-013-5 - Active Intermediate Individual Intermediate use only 04-01-2016 View substance registered dossier
2-Amino-5-Chloro-N,3-Dimethylbenzamide
618-233-7 890707-28-5 Active Full Individual ≥ 1 to < 10 tonnes 15-06-2020 View substance registered dossier
2-amino-5-chlorobenzothiazole
451-710-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Amino-5-ethylphenol HCI
480-270-8 149861-22-3 Active NONS Individual Tonnage data confidential 18-12-2008 View substance registered dossier
2-amino-5-methylthiazole
423-800-5 7305-71-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-amino-5-nitrobenzonitrile
241-446-8 17420-30-3 No longer Valid Intermediate Individual No longer valid 25-09-2020 View substance registered dossier
2-amino-6-fluoro-N-phenylbenzamide
807-759-4 1417456-04-2 Cease Manufacture Intermediate Individual Cease manufacture 28-08-2015 View substance registered dossier
2-amino-6-{[(3S)-1-(3-methylbutanoyl)piperidin-3-yl]methoxy}benzonitrile
941-156-8 1554631-80-9 Active Intermediate Individual Intermediate use only 24-04-2014 View substance registered dossier
2-aminobenzene-1,4-disulphonic acid
202-669-6 98-44-2 Active Intermediate Individual Intermediate use only 04-02-2016 View substance registered dossier
2-aminocyclopent-1-ene-1-carbonitrile
917-554-2 2941-23-3 Active Intermediate Individual Intermediate use only 18-03-2013 View substance registered dossier
2-aminododecan-1-ol hydrochloride (1:1)
687-797-4 23551-91-9 Active Intermediate Individual Intermediate use only 02-09-2013 View substance registered dossier
2-aminoethanesulfinic acid
428-720-4 300-84-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-aminoethanol
205-483-3 141-43-5 No longer Valid Full Individual No longer valid 02-12-2011 View substance registered dossier
2-aminoethanol
205-483-3 141-43-5 Active Intermediate Individual Intermediate use only 07-01-2016 View substance registered dossier
2-aminoethanol
205-483-3 141-43-5 Active Intermediate Individual Intermediate use only 31-05-2013 View substance registered dossier
2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester, (1S,3S,5S)-
609-213-9 361440-67-7 Active Intermediate Individual Intermediate use only 20-03-2017 View substance registered dossier
2-benzotriazol-2-yl-4-methyl-6-(2-methylallyl)phenol
419-750-9 98809-58-6 Active Intermediate Individual Intermediate use only 22-09-2020 View substance registered dossier
2-benzotriazol-2-yl-4-methyl-6-(2-methylallyl)phenol
419-750-9 98809-58-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-benzoyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
700-599-5 54761-87-4 Active Intermediate Individual Intermediate use only 07-06-2011 View substance registered dossier
2-Benzyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine
605-122-3 157995-00-1 Active Intermediate Individual Intermediate use only 14-01-2019 View substance registered dossier
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
404-360-3 119313-12-1 Active Full Individual ≥ 10 to < 100 tonnes 01-09-2009 View substance registered dossier
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
404-360-3 119313-12-1 Active Full Individual ≥ 10 to < 100 tonnes 29-01-2014 View substance registered dossier
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
404-360-3 119313-12-1 Active Full Individual ≥ 1 to < 10 tonnes 22-08-2014 View substance registered dossier
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
404-360-3 119313-12-1 Active Full Individual ≥ 1 to < 10 tonnes 16-09-2011 View substance registered dossier
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
404-360-3 119313-12-1 Cease Manufacture Full Individual Cease manufacture 30-09-2010 View substance registered dossier
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
404-360-3 119313-12-1 Cease Manufacture Full Individual Cease manufacture 15-11-2012 View substance registered dossier
2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone
404-360-3 119313-12-1 Cease Manufacture Full Individual Cease manufacture 05-08-2015 View substance registered dossier
2-benzyl-2-methyl-3-butenitrile
407-870-4 97384-48-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-benzyloxyethanol
210-719-3 622-08-2 Active Full Individual ≥ 1 to < 10 tonnes 31-08-2020 View substance registered dossier
2-bromo-1-(3,5-dihydroxyphenyl)ethanone
613-114-6 62932-92-7 Active Intermediate Individual Intermediate use only 10-12-2013 View substance registered dossier
2-Bromo-2-methyl-1-[4-(methylthio)phenyl]-1-propanone
859-185-9 88324-55-4 Active Intermediate Individual Intermediate use only 21-08-2020 View substance registered dossier
2-bromo-2-nitropropanol
407-030-7 24403-04-1 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
2-bromo-3,3,3-trifluoroprop-1-ene
627-872-0 1514-82-5 Active Full Individual ≥ 10 to < 100 tonnes 23-02-2021 View substance registered dossier
2-bromo-5-hydroxy-4-methoxybenzaldehyde
426-540-0 2973-59-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-Bromo-6-fluoroaniline
464-930-2 65896-11-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-bromomalonaldehyde
430-470-6 2065-75-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-bromopropane
200-855-1 75-26-3 Active Intermediate Individual Intermediate use only 07-05-2013 View substance registered dossier
2-bromopropane
200-855-1 75-26-3 No longer Valid Intermediate Individual No longer valid 22-07-2010 View substance registered dossier
2-Butene, chlorinated, epoxidized, distn. residues
304-783-2 94279-39-7 Active Intermediate Individual Intermediate use only 10-02-2010 View substance registered dossier
2-Butenedioic acid(2E)-, di-C12-15-alkyl esters
457-790-9 142104-11-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride
424-560-4 151257-01-1 Active Intermediate Individual Intermediate use only 10-11-2010 View substance registered dossier
2-Butyl-3-(4-chlorobenzyl)-1,3-diazaspiro[4.4]non-1-en-4-one and (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-methanesulfonic acid
700-176-5 - Active Intermediate Individual Intermediate use only 25-01-2011 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - 2-alkoyloxyethyl hydrogen maleate, where alkoyl represents (by weight) 70 to 85% unsaturated octadecoyl, 0.5 to 10% saturated octadecoyl, and 2 to 18% saturated hexadecoyl 417-960-5 - - View substance registered dossier
SP QUIMICA SA Crta. Reus a Riudoms Km. 4, 1 43330 RIUDOMS TARRAGONA Spain Spain Active 2-amino-3-hydroxy-N'-[(E)-(2,3,4-trihydroxyphenyl)methylene]propanehydrazide hydrochloride (1:1) 940-411-0 1353749-74-2 - View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active 2-Amino-4,5-dimethyl-thiophene-3-carbonitrile 610-309-8 4651-94-9 2012 View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 2-amino-4-(4-methylpiperazin-1-yl) benzoic acid tertbutyl ester 829-017-9 1034975-35-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 2-amino-4-bromo-5-chlorobenzoic acid 424-700-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-amino-4-dimethylamino-6-trifluoroethoxy-1,3,5-triazine 415-500-8 145963-84-4 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 2-Amino-4-methylsulfonylaminomethylbenzoic acid methylester 480-220-5 393509-78-9 - View substance registered dossier
SupraPolix BV Horsten 1 5612 AX Eindhoven Netherlands Netherlands Active 2-amino-5-(2-hydroxyethyl)-6-methyl-4(3H)-pyrimidinone 814-705-3 6940-45-0 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active 2-amino-5-bromopyridin-3-yl 4-methylbenzenesulfonate 943-013-5 - - View substance registered dossier
ADAMA Agriculture BV Arnhemseweg 87 Postbus 355 3830 AK Leusden Netherlands Netherlands Active 2-Amino-5-Chloro-N,3-Dimethylbenzamide 618-233-7 890707-28-5 - View substance registered dossier
- - - - 2-amino-5-chlorobenzothiazole 451-710-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2-Amino-5-ethylphenol HCI 480-270-8 149861-22-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2-amino-5-methylthiazole 423-800-5 7305-71-7 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid 2-amino-5-nitrobenzonitrile 241-446-8 17420-30-3 2021 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Cease Manufacture 2-amino-6-fluoro-N-phenylbenzamide 807-759-4 1417456-04-2 2017 View substance registered dossier
LA MESTA CHIMIE FINE 1336 Route de l'Estéron 06830 GILETTE France France Active 2-amino-6-{[(3S)-1-(3-methylbutanoyl)piperidin-3-yl]methoxy}benzonitrile 941-156-8 1554631-80-9 - View substance registered dossier
Igcar Chemicals, S.L. Pol. Ind. Rubí Sud, c/ Domènech i Montaner, 35-55 08191 Rubí Barcelona Spain Spain Active 2-aminobenzene-1,4-disulphonic acid 202-669-6 98-44-2 2016 View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active 2-aminocyclopent-1-ene-1-carbonitrile 917-554-2 2941-23-3 - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active 2-aminododecan-1-ol hydrochloride (1:1) 687-797-4 23551-91-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-aminoethanesulfinic acid 428-720-4 300-84-5 - View substance registered dossier
Roche Diagnostics GmbH Sandhoferstrasse 116 68305 Mannheim Germany Germany No longer Valid 2-aminoethanol 205-483-3 141-43-5 2017 View substance registered dossier
Przedsiębiorstwo Produkcyjno- Consultingowe ADOB Sp. z o.o. Sp. jawna Kołodzieja 11 61-070 Poznań Poland Poland Poland Active 2-aminoethanol 205-483-3 141-43-5 - View substance registered dossier
Delamine B.V. Stationsplein 121 P.O. Box 473 3800 AL Amersfoort Netherlands Netherlands Active 2-aminoethanol 205-483-3 141-43-5 - View substance registered dossier
[Confidential] - - - 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aminocarbonyl)-, 1,1-dimethylethyl ester, (1S,3S,5S)- 609-213-9 361440-67-7 - View substance registered dossier
NOVEAL 16 rue Maurice Berteaux 95500 LE THILLAY France France Active 2-benzotriazol-2-yl-4-methyl-6-(2-methylallyl)phenol 419-750-9 98809-58-6 - View substance registered dossier
RHODIA OPERATIONS 52 rue de la Haie Coq 93300 AUBERVILLIERS France France Active 2-benzotriazol-2-yl-4-methyl-6-(2-methylallyl)phenol 419-750-9 98809-58-6 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active 2-benzoyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one 700-599-5 54761-87-4 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 2-Benzyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine 605-122-3 157995-00-1 2019 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 119313-12-1 2009 View substance registered dossier
RAHN (3) Hahnstrasse 70 D-60528 Frankfurt am Main Germany Germany Active 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 119313-12-1 2011; 2014 View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 119313-12-1 - View substance registered dossier
Only representative (No publishable name) - - Active 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 119313-12-1 - View substance registered dossier
Only representative (No publishable name) - - Cease Manufacture 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 119313-12-1 2019 View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Cease Manufacture 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 119313-12-1 2019 View substance registered dossier
GEELIO Umwelttechnologie GmbH Hans-Thoma-Strasse 25 D-68163 Mannheim Baden-Württemberg Germany Germany Cease Manufacture 2-benzyl-2-dimethylamino-4'-morpholinobutyrophenone 404-360-3 119313-12-1 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2-benzyl-2-methyl-3-butenitrile 407-870-4 97384-48-0 - View substance registered dossier
Cepra srl Via del Tintoretto, 6/2 40033 Casalecchio di Reno Bo Italy Italy Active 2-benzyloxyethanol 210-719-3 622-08-2 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 2-bromo-1-(3,5-dihydroxyphenyl)ethanone 613-114-6 62932-92-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 2-Bromo-2-methyl-1-[4-(methylthio)phenyl]-1-propanone 859-185-9 88324-55-4 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-bromo-2-nitropropanol 407-030-7 24403-04-1 - View substance registered dossier
Covance Clinical Development SA 012 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain Spain Active 2-bromo-3,3,3-trifluoroprop-1-ene 627-872-0 1514-82-5 2018; 2019; 2020; 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Austrian competent national authority. - - Active 2-bromo-5-hydroxy-4-methoxybenzaldehyde 426-540-0 2973-59-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 2-Bromo-6-fluoroaniline 464-930-2 65896-11-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 2-bromomalonaldehyde 430-470-6 2065-75-0 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 2-bromopropane 200-855-1 75-26-3 - View substance registered dossier
Contract Chemicals Ltd Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom United Kingdom No longer Valid 2-bromopropane 200-855-1 75-26-3 2021 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 2-Butene, chlorinated, epoxidized, distn. residues 304-783-2 94279-39-7 - View substance registered dossier
- - - - 2-Butenedioic acid(2E)-, di-C12-15-alkyl esters 457-790-9 142104-11-8 - View substance registered dossier
INKE, S.A. Area Industrial del Llobregat Argent, 1 08755 Castellbisbal Barcelona Spain Spain Active 2-butyl-1,3-diazaspiro[4.4]non-1-en-4-one hydrochloride 424-560-4 151257-01-1 2010 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 2-Butyl-3-(4-chlorobenzyl)-1,3-diazaspiro[4.4]non-1-en-4-one and (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-methanesulfonic acid 700-176-5 - 2009; 2011 View substance registered dossier

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