Registered substances

Registered substances

Registered substances

Please note:

As of end June 2022 we have processed and published all dossiers that had been pending since 14 October 2021. While daily processing has resumed there remains a processing queue. New submissions will be at the back of the processing queue, and may be slightly delayed before publication. We appreciate your understanding in this matter.

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
4-amino-6-chlorotoluene-3-sulphonic acid
201-837-6 88-51-7 Active Intermediate Individual Intermediate use only 30-05-2013 View substance registered dossier
4-amino-N,N-diethylaniline
202-214-1 93-05-0 Active Intermediate Individual Intermediate use only 02-06-2015 View substance registered dossier
4-amino-N-(2-ethylhexyl)benzenesulphonamide
258-799-9 53817-09-7 Active Intermediate Individual Intermediate use only 15-01-2015 View substance registered dossier
4-amino-N-(2-methylquinolin-8-yl)benzenesulfonamide
700-562-3 909782-32-7 Active Intermediate Individual Intermediate use only 07-05-2015 View substance registered dossier
4-aminoazobenzene
200-453-6 60-09-3 Active Intermediate Individual Intermediate use only 09-12-2015 View substance registered dossier
4-aminobenzoic acid
205-753-0 150-13-0 Active Intermediate Individual Intermediate use only 19-08-2013 View substance registered dossier
4-aminophenol
204-616-2 123-30-8 Active Intermediate Individual Intermediate use only 16-05-2013 View substance registered dossier
4-aminophenol
204-616-2 123-30-8 Active Intermediate Individual Intermediate use only 30-04-2014 View substance registered dossier
4-benzyl-2,6-dihydroxy-4-aza-heptylene bis(2,2-dimethyloctanoate)
VMZ95005
418-100-1 172964-15-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-benzyloxy-4'-(2,3-epoxy-2-methylprop-1-yloxy)diphenylsulfone
NTZ-95
408-220-2 141420-50-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-bromo-2-fluoro-1-trifluoromethoxybenzene
1-BROM-3-FLUOR-4-TRIFLUORMETHOXYBENZOL
430-850-1 105529-58-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-bromoanisole
203-252-1 104-92-7 Active Intermediate Individual Intermediate use only 30-01-2015 View substance registered dossier
4-Bromobenzo[b]thiophene
814-115-6 5118-13-8 Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
4-butoxy-2,2,6,6-tetramethyl-1-piperidinyloxy
482-430-2 - Active Full Individual ≥ 0 to < 10 tonnes 24-03-2021 View substance registered dossier
4-chloro-2,5-dimethoxyaniline
228-782-0 6358-64-1 Active Intermediate Individual Intermediate use only 08-03-2012 View substance registered dossier
4-chloro-2-nitroaniline 201-925-4 89-63-4 Active Intermediate Individual Intermediate use only 14-05-2013 View substance registered dossier
4-chloro-3,5-dinitro-α,α,α-trifluorotoluene
206-889-3 393-75-9 Cease Manufacture Intermediate Individual Cease manufacture 24-05-2013 View substance registered dossier
4-chloro-3,5-dinitro-α,α,α-trifluorotoluene
206-889-3 393-75-9 Active Intermediate Individual Intermediate use only 26-04-2011 View substance registered dossier
4-chloro-3-nitrobenzonitrile
213-364-2 939-80-0 Active Intermediate Individual Intermediate use only 12-07-2018 View substance registered dossier
4-chloro-α,α,α-trifluoro-3-nitrotoluene
204-451-6 121-17-5 Active Intermediate Individual Intermediate use only 30-10-2012 View substance registered dossier
4-chloro-α,α,α-trifluorotoluene
202-681-1 98-56-6 Cease Manufacture Intermediate Individual Cease manufacture 24-05-2013 View substance registered dossier
4-chloroaniline
203-401-0 106-47-8 Active Intermediate Individual Intermediate use only 25-09-2012 View substance registered dossier
4-chloroaniline
203-401-0 106-47-8 No longer Valid Intermediate Individual No longer valid 21-02-2014 View substance registered dossier
4-chloroaniline
203-401-0 106-47-8 Active Intermediate Individual Intermediate use only 12-10-2010 View substance registered dossier
4-chlorobenzaldehyde
203-247-4 104-88-1 Active Intermediate Individual Intermediate use only 30-11-2012 View substance registered dossier
4-chlorobenzhydryl alcohol
204-333-4 119-56-2 Active Intermediate Individual Intermediate use only 14-07-2011 View substance registered dossier
4-chlorobutyl veratrate
CHLORO ESTER; CHLOROESTER
410-950-1 69788-75-6 Active Intermediate Individual Intermediate use only 17-02-2010 View substance registered dossier
4-chlorophenol
203-402-6 106-48-9 Active Intermediate Individual Intermediate use only 17-07-2015 View substance registered dossier
4-chlorophenyl cyclopropyl ketone O-(4-aminobenzyl)oxime
ACC ETHER
405-260-2 94050-51-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-chlorophenyl isocyanate
203-176-9 104-12-1 Active Intermediate Individual Intermediate use only 17-10-2012 View substance registered dossier
4-CPH
428-130-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-cyanobenzoyl chloride
228-005-5 6068-72-0 Active Intermediate Individual Intermediate use only 30-05-2018 View substance registered dossier
4-dichloroacetyl-1-oxa-4-azaspiro[4.5]decane
401-130-4 71526-07-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-dimethylaminobenzenediazonium 3-carboxy-4-hydroxybenzenesulfonate
DIAZO-A-SALICYLSULFONATE
404-980-4 124737-31-1 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-ethyl-2-fluoro-4'-(2-(trans-4-pentylcyclohexyl)ethyl)biphenyl
LICRISTAL I 52 (IS 1158)
433-390-1 95379-18-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-ethyl-2-fluoro-4'-(2-(trans-4-propylcyclohexyl)ethyl)biphenyl
LICRISTAL I 32 (IS 1156)
433-190-2 95379-51-4 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-ethyl-2-methyl-2-isopentyl-1,3-oxazolidine
ZOLDINE (R) MS-52
410-470-2 137796-06-6 Active NONS Individual Tonnage data confidential 23-10-2012 View substance registered dossier
4-fluoro-3-nitrobenzonitrile
640-317-7 1009-35-4 Active Intermediate Individual Intermediate use only 20-08-2020 View substance registered dossier
4-fluorobenzonitrile
214-784-9 1194-02-1 Active Intermediate Individual Intermediate use only 19-06-2020 View substance registered dossier
4-Hexenal, 6-(2,2,3-trimethyl-3-cyclopenten-1-yl)-
484-020-9 1016902-02-5 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-hexylresorcinol
205-257-4 136-77-6 Active Full Individual ≥ 1 to < 10 tonnes 21-02-2017 View substance registered dossier
4-hydroxy-7-(2-aminoethyl)-1,3-benzothiazol-2(3H)-one hydrochloride
432-470-1 189012-93-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-hydroxybenzohydrazide
226-326-5 5351-23-5 Active Intermediate Individual Intermediate use only 08-03-2018 View substance registered dossier
4-hydroxyphenyl-alpha-D-glucopyranoside
ALPHARBUTIN
440-470-8 84380-01-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-isocyanato-2-methyl-1-{4-[(trifluoromethyl)thio]phenoxy}benzene
690-654-9 106310-19-4 Active Intermediate Individual Intermediate use only 19-08-2019 View substance registered dossier
4-isothiocyanato-2-(trifluoromethyl)benzonitrile
700-928-2 143782-23-4 No longer Valid Intermediate Individual No longer valid 24-05-2013 View substance registered dossier
4-Methanesulfonyl-2-(trifluoromethyl)benzaldehyde
812-681-9 1215310-75-0 Active Intermediate Individual Intermediate use only 27-11-2018 View substance registered dossier
4-methoxy-3-nitro-N-phenylbenzamide
202-572-9 97-32-5 Active Intermediate Individual Intermediate use only 01-06-2016 View substance registered dossier
4-Methoxy-N-(3-N',N'-dimethylaminopropyl) naphthalimide 2-hydroxy-3-allyloxypropyl ammonium hydroxide
461-080-4 - Active NONS Individual Tonnage data confidential 06-09-2010 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
GCLE
403-040-0 104146-10-3 Active Intermediate Individual Intermediate use only 16-11-2011 View substance registered dossier
4-methoxyphenylacetone
204-578-7 122-84-9 Active Intermediate Individual Intermediate use only 18-02-2016 View substance registered dossier
4-methyl-2,6-bis(phenylamino)nicotinonitrile
810-804-0 51566-48-4 No longer Valid Intermediate Individual No longer valid 28-08-2018 View substance registered dossier
4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine dihydrobromide
946-432-1 - Active Intermediate Individual Intermediate use only 09-01-2018 View substance registered dossier
4-methyl-8-methylenetricyclo[3.3.1.13,7]decan-2-ol
PRISMANTOL
406-330-5 122760-84-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-N,N-bis(2-(((4-methylphenyl)sulfonyl)amino)ethyl)benzenesulfonamide
DIETHYLEN-TRIAMIN-TRITOSYLAT
413-300-5 56187-04-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-methyl-N-(methylsulfonyl)benzenesulfonamide
POWDERLINK (R) MTSI
415-040-8 14653-91-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Methyl-N3-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine dihydrochloride
700-594-8 1143459-92-0 Active Intermediate Individual Intermediate use only 25-10-2012 View substance registered dossier
4-methylanisole
203-253-7 104-93-8 No longer Valid Full Individual No longer valid 22-10-2010 View substance registered dossier
4-methylanisole
203-253-7 104-93-8 Active Intermediate Individual Intermediate use only 25-06-2013 View substance registered dossier
4-methylphenyl 4-methoxybenzoate
ME 10.1
439-300-5 58600-95-6 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-methylpyrazole
231-445-0 7554-65-6 Active Intermediate Individual Intermediate use only 08-10-2014 View substance registered dossier
4-morpholinopropanesulphonic acid
214-478-5 1132-61-2 Active Intermediate Individual Intermediate use only 09-11-2017 View substance registered dossier
4-nitro-o-anisidine
202-588-6 97-52-9 Active Intermediate Individual Intermediate use only 30-05-2013 View substance registered dossier
4-nitro-o-anisidine
202-588-6 97-52-9 Active Intermediate Individual Intermediate use only 14-10-2013 View substance registered dossier
4-nitroaniline
202-810-1 100-01-6 Active Intermediate Individual Intermediate use only 10-05-2013 View substance registered dossier
4-nitrobenzoic acid
200-526-2 62-23-7 Active Intermediate Individual Intermediate use only 21-12-2012 View substance registered dossier
4-nitrotoluene
202-808-0 99-99-0 Active Intermediate Individual Intermediate use only 04-07-2012 View substance registered dossier
4-nitrotoluene-2-sulphonic acid
204-445-3 121-03-9 Active Intermediate Individual Intermediate use only 17-07-2013 View substance registered dossier
4-nitrotoluene-2-sulphonic acid
204-445-3 121-03-9 Active Intermediate Individual Intermediate use only 22-10-2012 View substance registered dossier
4-nitrotoluene-2-sulphonic acid
204-445-3 121-03-9 Active Intermediate Individual Intermediate use only 21-01-2015 View substance registered dossier
4-Octanol, 3-amino-
482-070-6 1001354-72-8 Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R,3Z,5R)-, compd. with 2,4,4-trimethyl-2-pentanamine (1:1)
613-879-6 66069-32-7 Active Intermediate Individual Intermediate use only 20-05-2013 View substance registered dossier
4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, [2R-(2.alpha.,3Z,5.alpha.)]-, compd. with N,N'-bis(1-methylethyl)-1,2-ethanediamine (2:1)
700-781-4 160332-89-8 Active Intermediate Individual Intermediate use only 30-03-2012 View substance registered dossier
4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)-
806-511-2 35877-42-0 Active Intermediate Individual Intermediate use only 13-02-2014 View substance registered dossier
4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)-5-[[4-(diethylamino)-2-methoxyphenyl]methylene]-
457-890-2 860399-11-7 Active Full Individual ≥ 1 to < 10 tonnes 04-04-2014 View substance registered dossier
4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)-5-[[4-(diethylamino)-2-methoxyphenyl]methylene]-
457-890-2 860399-11-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Penten-1-one, 1-phenyl-
402-310-5 3240-29-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Penten-1-one, 1-spiro[4.5]dec-7-en-7-yl-
438-060-9 224031-70-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Piperidinone, 2,6-diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)-
440-550-2 244021-01-0 Active Full Individual ≥ 1 to < 10 tonnes 25-03-2011 View substance registered dossier
4-Piperidinone, 2,6-diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)-
440-550-2 244021-01-0 Active Full Individual ≥ 1 to < 10 tonnes 24-03-2011 View substance registered dossier
4-poly(propyl), benzene sulfonic acid
919-274-6 - Active Intermediate Individual Intermediate use only 10-12-2012 View substance registered dossier
4-Pyrimidinamine, 5-bromo-2-chloro-N-cyclopentyl-
800-067-3 733039-20-8 Active Intermediate Individual Intermediate use only 13-01-2017 View substance registered dossier
4-Pyrimidinecarboxamide, 2-(1-amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-
465-070-0 518048-03-8 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1)
639-694-0 188416-20-8 Cease Manufacture Intermediate Individual Cease manufacture 17-12-2010 View substance registered dossier
4-tert-butyl-2-(5-tert-butyl-2-oxo-2,3-dihydro-1-benzofuran-3-yl)phenyl 3,5-di-tert-butyl-4-hydroxybenzoate
700-641-2 1261240-30-5 Active Full Individual ≥ 1 to < 10 tonnes 01-06-2016 View substance registered dossier
4-tert-butylbenzaldehyde
213-367-9 939-97-9 Active Intermediate Individual Intermediate use only 14-08-2013 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 30-11-2010 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 13-04-2015 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 15-08-2013 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 27-11-2012 View substance registered dossier
4-tert-butylbenzoic acid
202-696-3 98-73-7 Active Intermediate Individual Intermediate use only 31-03-2015 View substance registered dossier
4-TERT-BUTYLCYCLOHEXANE-1-CARBOXYLIC ACID
611-163-8 5451-55-8 No longer Valid Intermediate Individual No longer valid 26-11-2019 View substance registered dossier
4-tert-butylphenol
202-679-0 98-54-4 Cease Manufacture Intermediate Individual Cease manufacture 26-07-2011 View substance registered dossier
4-Thiazoleacetic acid, 2-(formylamino)-α-oxo-
613-733-1 64987-06-0 Active Intermediate Individual Intermediate use only 27-10-2017 View substance registered dossier
4-Thiazoleethanethioic acid, .alpha.-[(acetyloxy)imino]-2-amino-, S-2-benzothiazolyl ester, (.alpha.Z)-
457-660-1 104797-47-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-, hydrochloride (1:2)
937-695-3 1185167-55-8 Active Intermediate Individual Intermediate use only 31-07-2012 View substance registered dossier
4-THIAZOLIDINE CARBOXYLIC ETHYL ESTER HCl
613-908-2 66223-38-9 Active Intermediate Individual Intermediate use only 18-01-2018 View substance registered dossier
4-{6-[4-(1,5-disulfo-2-naphthylazo)-2-methoxy-5-methylphenylazo]-5-hydroxy-7-sulfo-2-naphthylazo}-4,5-dihydro-5-oxo-1-(4-sulfophenyl)-1H-pyrazole-3-carboxylicacid, mixed lithium and sodium salts.
466-670-5 - Active NONS Individual Tonnage data confidential 24-11-2010 View substance registered dossier
4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one
828-315-6 1443532-21-5 Active Intermediate Individual Intermediate use only 22-11-2019 View substance registered dossier
493 F
437-020-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Ferro Performance Pigments Belgium N.V. Kortrijkstraat 153 8930 Menen Belgium Belgium Active 4-amino-6-chlorotoluene-3-sulphonic acid 201-837-6 88-51-7 - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 4-amino-N,N-diethylaniline 202-214-1 93-05-0 - View substance registered dossier
Sun Chemical Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 4-amino-N-(2-ethylhexyl)benzenesulphonamide 258-799-9 53817-09-7 - View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS Boulevard Dambourney 76350 Oissel France France Active 4-amino-N-(2-methylquinolin-8-yl)benzenesulfonamide 700-562-3 909782-32-7 2015 View substance registered dossier
Sun Chemical Colors & Effects GmbH An der Rheinschanze 1 67059 Ludwigshafen Germany Germany Active 4-aminoazobenzene 200-453-6 60-09-3 2015 View substance registered dossier
[Confidential] - - - 4-aminobenzoic acid 205-753-0 150-13-0 - View substance registered dossier
CHEMI S.p.A. Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy Italy Active 4-aminophenol 204-616-2 123-30-8 - View substance registered dossier
[Confidential] - - - 4-aminophenol 204-616-2 123-30-8 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 4-benzyl-2,6-dihydroxy-4-aza-heptylene bis(2,2-dimethyloctanoate) 418-100-1 172964-15-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-benzyloxy-4'-(2,3-epoxy-2-methylprop-1-yloxy)diphenylsulfone 408-220-2 141420-50-0 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 4-bromo-2-fluoro-1-trifluoromethoxybenzene 430-850-1 105529-58-6 2019 View substance registered dossier
REACh ChemConsult GmbH Strehlener Str. 14 01069 Dresden Germany Germany Active 4-bromoanisole 203-252-1 104-92-7 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active 4-Bromobenzo[b]thiophene 814-115-6 5118-13-8 - View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active 4-butoxy-2,2,6,6-tetramethyl-1-piperidinyloxy 482-430-2 - 2014; 2016; 2021 View substance registered dossier
Only representative (No publishable name) - - Active 4-chloro-2,5-dimethoxyaniline 228-782-0 6358-64-1 - View substance registered dossier
Only representative (No publishable name) - - Active 4-chloro-2-nitroaniline 201-925-4 89-63-4 - View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands Netherlands Cease Manufacture 4-chloro-3,5-dinitro-α,α,α-trifluorotoluene 206-889-3 393-75-9 2019 View substance registered dossier
Finchimica S.p.A. Via Lazio 13, 25025 Manerbio (BS) Italy Italy Active 4-chloro-3,5-dinitro-α,α,α-trifluorotoluene 206-889-3 393-75-9 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active 4-chloro-3-nitrobenzonitrile 213-364-2 939-80-0 - View substance registered dossier
CHEMICAL INSPECTION & REGULATION SERVICE LIMITED Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4-chloro-α,α,α-trifluoro-3-nitrotoluene 204-451-6 121-17-5 2012 View substance registered dossier
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands Netherlands Cease Manufacture 4-chloro-α,α,α-trifluorotoluene 202-681-1 98-56-6 2019 View substance registered dossier
ALCHEMIE INDUSTRIES CHEMICAL SPAIN, S.L. Atlantida, 21 1º3º 08930 Sant Adria de Besos Spain Spain Active 4-chloroaniline 203-401-0 106-47-8 2012 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 4-chloroaniline 203-401-0 106-47-8 2018 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-chloroaniline 203-401-0 106-47-8 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active 4-chlorobenzaldehyde 203-247-4 104-88-1 - View substance registered dossier
Cosma S.p.A. Via Colleoni 15/17 24040 Ciserano (BG) Italy Italy Active 4-chlorobenzhydryl alcohol 204-333-4 119-56-2 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active 4-chlorobutyl veratrate 410-950-1 69788-75-6 - View substance registered dossier
[Confidential] - - - 4-chlorophenol 203-402-6 106-48-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-chlorophenyl cyclopropyl ketone O-(4-aminobenzyl)oxime 405-260-2 94050-51-8 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-chlorophenyl isocyanate 203-176-9 104-12-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-CPH 428-130-7 - - View substance registered dossier
Chemische Fabrik Karl Bucher GmbH An der Guenz 1 89367 Waldstetten Germany Germany Active 4-cyanobenzoyl chloride 228-005-5 6068-72-0 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active 4-dichloroacetyl-1-oxa-4-azaspiro[4.5]decane 401-130-4 71526-07-3 - View substance registered dossier
Merck Performance Materials GmbH Rheingaustrasse 190-196 65203 Wiesbaden Germany Germany Cease Manufacture 4-dimethylaminobenzenediazonium 3-carboxy-4-hydroxybenzenesulfonate 404-980-4 124737-31-1 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-ethyl-2-fluoro-4'-(2-(trans-4-pentylcyclohexyl)ethyl)biphenyl 433-390-1 95379-18-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-ethyl-2-fluoro-4'-(2-(trans-4-propylcyclohexyl)ethyl)biphenyl 433-190-2 95379-51-4 - View substance registered dossier
ANGUS CHEMIE GMBH Zeppelinstr. 30 Postfach 4003 D-49479 Ibbenbueren-Uffeln Germany Germany Active 4-ethyl-2-methyl-2-isopentyl-1,3-oxazolidine 410-470-2 137796-06-6 2011; 2012 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active 4-fluoro-3-nitrobenzonitrile 640-317-7 1009-35-4 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active 4-fluorobenzonitrile 214-784-9 1194-02-1 - View substance registered dossier
- - - - 4-Hexenal, 6-(2,2,3-trimethyl-3-cyclopenten-1-yl)- 484-020-9 1016902-02-5 - View substance registered dossier
Sytheon France 112 rue de Paris 92100 Boulogne Billancourt France France Active 4-hexylresorcinol 205-257-4 136-77-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-hydroxy-7-(2-aminoethyl)-1,3-benzothiazol-2(3H)-one hydrochloride 432-470-1 189012-93-9 - View substance registered dossier
SP QUIMICA SA Crta. Reus a Riudoms Km. 4, 1 43330 RIUDOMS TARRAGONA Spain Spain Active 4-hydroxybenzohydrazide 226-326-5 5351-23-5 - View substance registered dossier
- - - - 4-hydroxyphenyl-alpha-D-glucopyranoside 440-470-8 84380-01-8 - View substance registered dossier
Bayer Animal Health GmbH Alfred Nobel Straße 50 40789 Monheim Germany Germany Active 4-isocyanato-2-methyl-1-{4-[(trifluoromethyl)thio]phenoxy}benzene 690-654-9 106310-19-4 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid 4-isothiocyanato-2-(trifluoromethyl)benzonitrile 700-928-2 143782-23-4 2021 View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active 4-Methanesulfonyl-2-(trifluoromethyl)benzaldehyde 812-681-9 1215310-75-0 - View substance registered dossier
Colorants Solutions Deutschland GmbH Brüningstrasse 50 65929 Frankfurt am Main Germany Germany Active 4-methoxy-3-nitro-N-phenylbenzamide 202-572-9 97-32-5 - View substance registered dossier
Nalco Europe B.V. Oude Rhijnhofweg 17 2342 BB Oegstgeest Netherlands Netherlands Active 4-Methoxy-N-(3-N',N'-dimethylaminopropyl) naphthalimide 2-hydroxy-3-allyloxypropyl ammonium hydroxide 461-080-4 - 2010 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 104146-10-3 - View substance registered dossier
BENECHIM René Magritte 163 7860 Lessines Belgium Belgium Active 4-methoxyphenylacetone 204-578-7 122-84-9 - View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid 4-methyl-2,6-bis(phenylamino)nicotinonitrile 810-804-0 51566-48-4 2021 View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active 4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine dihydrobromide 946-432-1 - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active 4-methyl-8-methylenetricyclo[3.3.1.13,7]decan-2-ol 406-330-5 122760-84-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-methyl-N,N-bis(2-(((4-methylphenyl)sulfonyl)amino)ethyl)benzenesulfonamide 413-300-5 56187-04-3 - View substance registered dossier
Cytec Industries BV Weena 505 3013 AL Rotterdam Netherlands Netherlands Active 4-methyl-N-(methylsulfonyl)benzenesulfonamide 415-040-8 14653-91-9 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active 4-Methyl-N3-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]benzene-1,3-diamine dihydrochloride 700-594-8 1143459-92-0 2012 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany No longer Valid 4-methylanisole 203-253-7 104-93-8 2013 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-methylanisole 203-253-7 104-93-8 - View substance registered dossier
- - - - 4-methylphenyl 4-methoxybenzoate 439-300-5 58600-95-6 - View substance registered dossier
[Confidential] - - - 4-methylpyrazole 231-445-0 7554-65-6 - View substance registered dossier
Raschig GmbH Mundenheimerstraße 100 D-67061 Ludwigshafen Germany Germany Active 4-morpholinopropanesulphonic acid 214-478-5 1132-61-2 - View substance registered dossier
Ferro Performance Pigments Belgium N.V. Kortrijkstraat 153 8930 Menen Belgium Belgium Active 4-nitro-o-anisidine 202-588-6 97-52-9 - View substance registered dossier
Only representative (No publishable name) - - Active 4-nitro-o-anisidine 202-588-6 97-52-9 - View substance registered dossier
Only representative (No publishable name) - - Active 4-nitroaniline 202-810-1 100-01-6 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4-nitrobenzoic acid 200-526-2 62-23-7 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-nitrotoluene 202-808-0 99-99-0 - View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active 4-nitrotoluene-2-sulphonic acid 204-445-3 121-03-9 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active 4-nitrotoluene-2-sulphonic acid 204-445-3 121-03-9 - View substance registered dossier
Only representative (No publishable name) - - Active 4-nitrotoluene-2-sulphonic acid 204-445-3 121-03-9 2013; 2015 View substance registered dossier
DOW BENELUX B.V. - OR2 Postbus 48 4530 AA Terneuzen Netherlands Netherlands Cease Manufacture 4-Octanol, 3-amino- 482-070-6 1001354-72-8 2015 View substance registered dossier
SUANFARMA Italia SpA Corso Verona, 165 38068 Rovereto Trentino Alto Adige Italy Italy Active 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R,3Z,5R)-, compd. with 2,4,4-trimethyl-2-pentanamine (1:1) 613-879-6 66069-32-7 - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, [2R-(2.alpha.,3Z,5.alpha.)]-, compd. with N,N'-bis(1-methylethyl)-1,2-ethanediamine (2:1) 700-781-4 160332-89-8 - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)- 806-511-2 35877-42-0 - View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)-5-[[4-(diethylamino)-2-methoxyphenyl]methylene]- 457-890-2 860399-11-7 - View substance registered dossier
- - - - 4-Oxazolidinone, 3-cyclohexyl-2-(cyclohexylimino)-5-[[4-(diethylamino)-2-methoxyphenyl]methylene]- 457-890-2 860399-11-7 - View substance registered dossier
International Flavors & Fragrances I.F.F. (Nederland) B.V. Liebergerweg 72-98 1221 JT Hilversum Netherlands Netherlands Active 4-Penten-1-one, 1-phenyl- 402-310-5 3240-29-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-Penten-1-one, 1-spiro[4.5]dec-7-en-7-yl- 438-060-9 224031-70-3 - View substance registered dossier
BASF Nederland B.V. Groningensingel 1 Postbus 1019 6801 MC Arnhem Netherlands Netherlands Active 4-Piperidinone, 2,6-diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)- 440-550-2 244021-01-0 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-Piperidinone, 2,6-diethyl-2,3,6-trimethyl-1-(1-phenylethoxy)- 440-550-2 244021-01-0 - View substance registered dossier
Chevron Oronite SA M/I Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France France Active 4-poly(propyl), benzene sulfonic acid 919-274-6 - 2012 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active 4-Pyrimidinamine, 5-bromo-2-chloro-N-cyclopentyl- 800-067-3 733039-20-8 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active 4-Pyrimidinecarboxamide, 2-(1-amino-1-methylethyl)-N-[(4-fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo- 465-070-0 518048-03-8 - View substance registered dossier
Medichem Manufacturing (Malta) Limited HF 61-Hal Far Industrial Estate BBG 3000 Hal Far Malta Malta Malta Cease Manufacture 4-Pyrimidineethanol, 6-chloro-.alpha.-(2,4-difluorophenyl)-5-fluoro-.beta.-methyl-.alpha.-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1) 639-694-0 188416-20-8 2017 View substance registered dossier
GEELIO Umwelttechnologie GmbH Langgasse 28 D-55234 Hochborn Rheinland-Pfalz Germany Germany Active 4-tert-butyl-2-(5-tert-butyl-2-oxo-2,3-dihydro-1-benzofuran-3-yl)phenyl 3,5-di-tert-butyl-4-hydroxybenzoate 700-641-2 1261240-30-5 2012; 2016 View substance registered dossier
Givaudan Iberica SA Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain Spain Active 4-tert-butylbenzaldehyde 213-367-9 939-97-9 2013 View substance registered dossier
Only representative (No publishable name) - - Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 2013 View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland Ireland Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 2012 View substance registered dossier
AlzChem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active 4-tert-butylbenzoic acid 202-696-3 98-73-7 2015 View substance registered dossier
Robinson Brothers Ltd Phoenix Street B70 0AH West Bromwich West Midlands United Kingdom United Kingdom No longer Valid 4-TERT-BUTYLCYCLOHEXANE-1-CARBOXYLIC ACID 611-163-8 5451-55-8 2021 View substance registered dossier
SI Group France (FRAA), SAS 2 Chemin du Trou Bieuet 60840 Catenoy 60 France France Cease Manufacture 4-tert-butylphenol 202-679-0 98-54-4 2019 View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active 4-Thiazoleacetic acid, 2-(formylamino)-α-oxo- 613-733-1 64987-06-0 - View substance registered dossier
SUANFARMA Italia SpA Corso Verona, 165 38068 Rovereto Trentino Alto Adige Italy Italy Active 4-Thiazoleethanethioic acid, .alpha.-[(acetyloxy)imino]-2-amino-, S-2-benzothiazolyl ester, (.alpha.Z)- 457-660-1 104797-47-9 - View substance registered dossier
Flamma S.p.a. via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy Italy Active 4-Thiazolemethanamine, N-methyl-2-(1-methylethyl)-, hydrochloride (1:2) 937-695-3 1185167-55-8 - View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active 4-THIAZOLIDINE CARBOXYLIC ETHYL ESTER HCl 613-908-2 66223-38-9 - View substance registered dossier
Fujifilm Europe GmbH (OR2) Balcke-Dürr-Allee 6 40882 Ratingen Germany Germany Active 4-{6-[4-(1,5-disulfo-2-naphthylazo)-2-methoxy-5-methylphenylazo]-5-hydroxy-7-sulfo-2-naphthylazo}-4,5-dihydro-5-oxo-1-(4-sulfophenyl)-1H-pyrazole-3-carboxylicacid, mixed lithium and sodium salts. 466-670-5 - 2010 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-{[4-amino-5-bromo-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl}piperazin-2-one 828-315-6 1443532-21-5 - View substance registered dossier
Honeywell Specialty Chemicals Seelze GmbH Wunstorfer Strasse 40 D-30926 Seelze Lower Saxony Germany Germany Active 493 F 437-020-8 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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