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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 22 July 2021. Database contains 23346 unique substances and contains information from 104205 dossiers.
Substance identity
Administrative data
Submission type:
First published date:
Last update date:
Substance data
Select total tonnage band range:

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Uses and exposure
Life cycle:
  • Consumer Uses
  • Article service life
  • Widespread uses by professional workers
  • Formulation or re-packing
  • Uses at industrial sites
  • Manufacture
Category:
Details
(1aR,5S,8S,10R,22aR)·5 tert·butyl-14·methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a tetradecahydro-8H-7,10·methanocyclopropa(18,19)(1,10,3,6)dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid
943-551-0 - Active Intermediate Joint Intermediate use only 24-05-2017 View substance registered dossier
(1E)-1-chloro-3,3,3-trifluoroprop-1-ene
700-486-0 102687-65-0 Active Full Joint ≥ 1 000 to < 10 000 tonnes 27-02-2020 View substance registered dossier
(1E)-5-methyl-1-phenylhex-1-en-3-one
808-311-0 60796-12-5 Active Intermediate Individual Intermediate use only 24-02-2015 View substance registered dossier
(1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine
700-765-7 100485-51-6 Cease Manufacture Intermediate Individual Cease manufacture 07-12-2012 View substance registered dossier
(1E,4S)-4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydronaphthalen-1(2H)-imine
811-284-8 312620-93-2 Active Intermediate Joint Intermediate use only 02-06-2016 View substance registered dossier
(1E,Z)-2,6-dimethylhepta-1,5-dienyl 2-methylpropanoate
479-370-4 942594-24-3 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium (2S)-2-(6-methoxy-2-naphthyl)propanoate
941-846-9 - Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
(1R)-1-(4-methylphenyl)ethylamine (2S)-5-oxopyrrolidine-2-carboxylate
814-654-7 122170-65-4 Active Intermediate Joint Intermediate use only 29-03-2018 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 100 to < 1 000 tonnes 16-01-2015 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 100 to < 1 000 tonnes 21-02-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Joint ≥ 100 to < 1 000 tonnes 09-07-2021 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 10 to < 100 tonnes 13-04-2015 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 10 to < 100 tonnes 22-03-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 10 to < 100 tonnes 05-11-2010 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 22-01-2016 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 23-09-2014 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 25-03-2015 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active Full Individual ≥ 1 to < 10 tonnes 27-10-2011 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 02-04-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 17-08-2012 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Cease Manufacture Full Individual Cease manufacture 21-05-2013 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
413-110-2 135861-56-2 Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(1R)-1-[(4R,4aR,8aS)-2,6-bis(4-chlorophenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
700-591-1 82203-23-4 Active Full Joint ≥ 10 to < 100 tonnes 06-12-2018 View substance registered dossier
(1R)-1-isopropyl-4-methyl-cyclohex-3-en-1-ol
943-985-0 20126-76-5 Active Full Joint ≥ 10 to < 100 tonnes 04-03-2021 View substance registered dossier
(1R)-1-Naphthylethylamine Hydrochloride
617-358-4 82572-04-1 Active Intermediate Joint Intermediate use only 02-05-2018 View substance registered dossier
(1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
600-381-9 1030385-16-0 Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
(1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
600-381-9 1030385-16-0 Active Intermediate Individual Intermediate use only 20-11-2014 View substance registered dossier
(1R)-2-(benzyl{(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1)
927-046-2 1180001-17-5 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
(1R)-2-(benzyl{(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1)
927-046-2 1180001-17-5 Active Intermediate Individual Intermediate use only 17-10-2014 View substance registered dossier
(1R)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
807-025-3 1315508-94-1 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
(1R)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
807-026-9 1315508-93-0 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
(1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride
700-425-8 521284-22-0 Active Full Joint Tonnage data confidential 30-03-2016 View substance registered dossier
(1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol
252-744-2 35836-73-8 Active Full Joint ≥ 10 to < 100 tonnes 18-05-2021 View substance registered dossier
(1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid
252-817-9 35963-20-3 Active Intermediate Joint Intermediate use only 07-01-2020 View substance registered dossier
(1R)-cyclohex-3-ene-1-carboxylic acid
634-674-8 5709-98-8 Active Intermediate Joint Intermediate use only 11-09-2017 View substance registered dossier
(1R)cyclohex-3-enecarboxylic acid (1S)-1-phenylethylamine
814-700-6 67976-81-2 Active Intermediate Joint Intermediate use only 03-10-2017 View substance registered dossier
(1R*,6S*)-6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium monooxalate
700-689-4 41524-32-7 Active Intermediate Individual Intermediate use only 21-09-2011 View substance registered dossier
(1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride
609-015-2 3464-71-9 Active Intermediate Joint Intermediate use only 12-03-2018 View substance registered dossier
(1R, 4R, 5S) 4-hydroxy-6,6-dimethyl-3-Oxabicyclo[3.1.0]hexan-2-one
619-753-7 73611-02-6 Active Intermediate Joint Intermediate use only 12-05-2014 View substance registered dossier
(1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate
607-316-3 240806-31-9 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile
608-856-2 33300-19-5 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,2R)-1,2-Cyclohexanedimethanol
692-053-7 65376-05-8 Active Intermediate Joint Intermediate use only 24-10-2018 View substance registered dossier
(1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate
445-910-2 - Active Full Joint ≥ 1 to < 10 tonnes 14-10-2016 View substance registered dossier
(1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride
943-460-6 - Active Intermediate Joint Intermediate use only 16-06-2020 View substance registered dossier
(1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide
600-115-1 1006376-62-0 Active Intermediate Individual Intermediate use only 29-01-2018 View substance registered dossier
(1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid
609-759-8 39961-95-0 Active Intermediate Joint Intermediate use only 29-01-2018 View substance registered dossier
(1R,2R,3S,4S)-1-(1,1,3,3-tetraoxido-1,3-dithian-2-yl)pentane-1,2,3,4-tetrol
936-126-6 1352707-53-9 Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
(1R,2R,3S,4S)-1-(1,3-dithian-2-yl)pentane-1,2,3,4-tetrol
936-125-0 1352707-52-8 Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
(1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol
606-948-7 2217-02-9 Active Full Joint ≥ 10 to < 100 tonnes 20-07-2020 View substance registered dossier
(1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate
807-751-0 4057-31-2 Active Full Joint ≥ 10 to < 100 tonnes 07-05-2018 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (1aR,5S,8S,10R,22aR)·5 tert·butyl-14·methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a tetradecahydro-8H-7,10·methanocyclopropa(18,19)(1,10,3,6)dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxylic acid 943-551-0 - - View substance registered dossier
Honeywell Belgium NV OR-1000 Gaston Geenslaan 14 - 2nd Floor Arenberg Wetenschapspark B-3001 Heverlee Belgium Belgium Active (1E)-1-chloro-3,3,3-trifluoroprop-1-ene 700-486-0 102687-65-0 2013; 2014; 2015; 2016 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active (1E)-1-chloro-3,3,3-trifluoroprop-1-ene 700-486-0 102687-65-0 2017 View substance registered dossier
Honeywell Fluorine Products Europe BV Stationsplein Zuid-West 961 1117 CE Schiphol-Oost Netherlands Netherlands Active (1E)-1-chloro-3,3,3-trifluoroprop-1-ene 700-486-0 102687-65-0 2016; 2020 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (1E)-5-methyl-1-phenylhex-1-en-3-one 808-311-0 60796-12-5 - View substance registered dossier
Minakem Dunkerque Production 224 avenue de la Dordogne Zone d'entreprises du Nord Gracht 59640 DUNKERQUE France France Cease Manufacture (1E)-N-hydroxy-1-(naphthalen-1-yl)ethanimine 700-765-7 100485-51-6 2019 View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active (1E,4S)-4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydronaphthalen-1(2H)-imine 811-284-8 312620-93-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (1E,Z)-2,6-dimethylhepta-1,5-dienyl 2-methylpropanoate 479-370-4 942594-24-3 - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (1R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium (2S)-2-(6-methoxy-2-naphthyl)propanoate 941-846-9 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)-1-(4-methylphenyl)ethylamine (2S)-5-oxopyrrolidine-2-carboxylate 814-654-7 122170-65-4 - View substance registered dossier
Covance Clinical Development SA 098 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain Spain Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2015 View substance registered dossier
TÜV SÜD Iberia, S.A.U. (068) Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain Spain Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2013 View substance registered dossier
Chemservice GmbH - (X88M) Herrnsheimer Hauptstrasse 1b 67550 Worms Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2013; 2018 View substance registered dossier
Peram Handelsgesellschaft mbH Dorotheenstraße 48 22301 Hamburg Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2014; 2020; 2021 View substance registered dossier
[Confidential] - - - (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
REACH24H CONSULTING GROUP Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland Ireland Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
ADEKA PALMAROLE SAS 13 rue du 17 Novembre FR-68100 MULHOSE France France Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
[Confidential] - - - (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
ADEKA POLYMER ADDITIVES EUROPE SAS 13 rue du 17 Novembre FR-68100 MULHOUSE France France Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
Handelsvertretung Sabine Alisch Fontaneweg 22 16547 Birkenwerder Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
Everspring Europe Sprl Rue Rodenbach 125 1190 Brussels Belgium Belgium Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2014 View substance registered dossier
Borealis AG Wagramerstrasse 17-19 1220 Wien Austria Austria Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
KTR Europe GmbH Mergenthalerallee 77 65760 Eschborn Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
ROQUETTE Frères 1 rue de la haute loge 62136 LESTREM Cedex France France Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2018 View substance registered dossier
REACH COMPLIANCE SERVICES LIMITED Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
REACH24H CONSULTING GROUP Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland Ireland Cease Manufacture (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
RiKA International Limited 3 Howarth Court, Gateway Crescent Broadway Business Park OL9 9XB Chadderton Oldham United Kingdom United Kingdom No longer Valid (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 2021 View substance registered dossier
Milliken Europe B.V.B.A. (OR) Ham 18-24 9000 Gent Belgium Belgium Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(3,4-dimethylphenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 413-110-2 135861-56-2 - View substance registered dossier
Chemservice GmbH - (X88M) Herrnsheimer Hauptstrasse 1b 67550 Worms Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(4-chlorophenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 700-591-1 82203-23-4 2018 View substance registered dossier
TRIGON Chemie GmbH Breitwiesenstr. 1 36381 Schluechtern Germany Germany Active (1R)-1-[(4R,4aR,8aS)-2,6-bis(4-chlorophenyl)tetrahydro[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol 700-591-1 82203-23-4 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R)-1-isopropyl-4-methyl-cyclohex-3-en-1-ol 943-985-0 20126-76-5 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R)-1-isopropyl-4-methyl-cyclohex-3-en-1-ol 943-985-0 20126-76-5 - View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (1R)-1-isopropyl-4-methyl-cyclohex-3-en-1-ol 943-985-0 20126-76-5 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R)-1-isopropyl-4-methyl-cyclohex-3-en-1-ol 943-985-0 20126-76-5 - View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (1R)-1-isopropyl-4-methyl-cyclohex-3-en-1-ol 943-985-0 20126-76-5 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)-1-Naphthylethylamine Hydrochloride 617-358-4 82572-04-1 - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 600-381-9 1030385-16-0 2018 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 600-381-9 1030385-16-0 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-(benzylamino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 600-381-9 1030385-16-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (1R)-2-(benzyl{(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1) 927-046-2 1180001-17-5 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-(benzyl{(2R)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1) 927-046-2 1180001-17-5 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-025-3 1315508-94-1 2017 View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (1R)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-025-3 1315508-94-1 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (1R)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-026-9 1315508-93-0 2016 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1R)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-026-9 1315508-93-0 2017 View substance registered dossier
[Confidential] - - - (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol hydrochloride 700-425-8 521284-22-0 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol 252-744-2 35836-73-8 2018 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (1R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-ethanol 252-744-2 35836-73-8 2017; 2021 View substance registered dossier
REACHLINKED OÜ Ahtri tn 12 10151 Tallinn Estonia Estonia Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
Aceto France SAS 3 Place Giovanni da Verrazzano 69009 Lyon France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
DKSH France S.A. 1475 Quai du Rhone 01702 Miribel France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 2018 View substance registered dossier
PORTA s.r.o. Zelený pruh 99 14002 Praha 4 Czech Republic Czech Republic Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 - View substance registered dossier
Medichem S.A. Polígon Industrial de Celrà 17460 Celrà Girona Spain Spain Active (1R)-[7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]methanesulphonic acid 252-817-9 35963-20-3 2018 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)-cyclohex-3-ene-1-carboxylic acid 634-674-8 5709-98-8 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R)cyclohex-3-enecarboxylic acid (1S)-1-phenylethylamine 814-700-6 67976-81-2 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (1R*,6S*)-6-(ethoxycarbonyl)-N,N-dimethyl-6-phenylcyclohex-2-en-1-aminium monooxalate 700-689-4 41524-32-7 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (1R, 3r, 5S)-3-hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1’-pyrrolidinium]chloride 609-015-2 3464-71-9 - View substance registered dossier
[Confidential] - - - (1R, 4R, 5S) 4-hydroxy-6,6-dimethyl-3-Oxabicyclo[3.1.0]hexan-2-one 619-753-7 73611-02-6 - View substance registered dossier
CRYSTAL PHARMA SAU Parque Tecnológico, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-acetyl-11a-methyl-2,3,3a,3b,4,5,6,8,9,11-decahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate 607-316-3 240806-31-9 2018 View substance registered dossier
CRYSTAL PHARMA SAU Parque Tecnológico, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,11aS)-1-hydroxy-11a-methyl-2,3,3a,5,6,8,9,11-octahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]-1-carbonitrile 608-856-2 33300-19-5 2018 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (1R,2R)-1,2-Cyclohexanedimethanol 692-053-7 65376-05-8 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 - 2010; 2011; 2012; 2014 View substance registered dossier
Swords Laboratories Cruiserath Road Mulhuddart D15H6EF Dublin 15 Co Dublin Ireland Ireland Active (1R,2R)-1,3-Dihydroxy-1-(4-nitrophenyl)propyl-2-ammonium (1R, 5S)-5-(dimethylphenylsilyl)-2-(hydroxymethyl)cyclopent-2-ene-1-carboxylate 445-910-2 - 2010; 2012; 2014; 2016 View substance registered dossier
AbbVie Ireland NL B.V. Manorhamilton Road none Sligo Ireland Ireland Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - - View substance registered dossier
AbbVie Logistics B.V. Zuiderzeelaan 53 8017 JV Zwolle Netherlands Netherlands Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (1R,2R)-1-amino-2-difluoromethyl)-N- (1-methylcyclopropylsulfonyl)cyclo propanecarboxyamide hydrochloride 943-460-6 - 2020 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (1R,2R)-2-(3,4-difluorophenyl)cyclopropane-1-carboxamide 600-115-1 1006376-62-0 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1R,2R)-cyclohexane-1,2-diamine (2R,3R)-2,3-dihydroxybutanedioic acid 609-759-8 39961-95-0 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (1R,2R,3S,4S)-1-(1,1,3,3-tetraoxido-1,3-dithian-2-yl)pentane-1,2,3,4-tetrol 936-126-6 1352707-53-9 - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (1R,2R,3S,4S)-1-(1,3-dithian-2-yl)pentane-1,2,3,4-tetrol 936-125-0 1352707-52-8 - View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 2019 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 2018 View substance registered dossier
LLUCH ESSENCE, S.L.U. Lo Gaiter, 160 08820 EL PRAT DE LLOBREGAT CATALUÑA Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-ol 606-948-7 2217-02-9 - View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate 807-751-0 4057-31-2 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,2R,4S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl acetate 807-751-0 4057-31-2 - View substance registered dossier

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