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Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 22 July 2021. Database contains 23346 unique substances and contains information from 104205 dossiers.
Substance identity
Administrative data
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First published date:
Last update date:
Substance data
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Uses and exposure
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Category:
Details
(3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime
603-883-6 134931-01-4 Active Intermediate Joint Intermediate use only 23-08-2016 View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
918-279-0 - Active Intermediate Joint Intermediate use only 26-04-2017 View substance registered dossier
(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one
700-290-5 63968-64-9 Active Intermediate Individual Intermediate use only 15-11-2012 View substance registered dossier
(3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
603-817-6 134395-00-9 Active Intermediate Joint Intermediate use only 28-09-2017 View substance registered dossier
(3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE
851-742-4 464207-51-0 Active Full Joint ≥ 1 to < 10 tonnes 28-05-2020 View substance registered dossier
(3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione
603-436-5 13076-17-0 Active Full Joint ≥ 1 000 to < 10 000 tonnes 26-07-2018 View substance registered dossier
(3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde
812-036-1 1214741-19-1 Cease Manufacture Intermediate Individual Cease manufacture 28-04-2016 View substance registered dossier
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
942-823-6 - Cease Manufacture Intermediate Individual Cease manufacture 03-11-2015 View substance registered dossier
(3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
810-392-2 171284-84-7 Cease Manufacture Intermediate Individual Cease manufacture 07-09-2015 View substance registered dossier
(3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate
228-502-7 6283-74-5 Active Intermediate Joint Intermediate use only 31-08-2018 View substance registered dossier
(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone
429-980-1 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(3S)-2-{N-[1-ethoxy-1-oxo-4-phenylbutan-2-yl]-substituted}-heteropolycyclic-3-carboxylic acid hydrochloride
919-408-3 - Active Intermediate Individual Intermediate use only 14-01-2020 View substance registered dossier
(3S)-3,7-Dimethyl-1-octanol
814-059-2 68680-98-8 Active Full Joint ≥ 1 to < 10 tonnes 30-05-2018 View substance registered dossier
(3S)-3,7-dimethylocta-1,6-dien-1-yl acetate
946-529-9 1439355-19-7 Active Intermediate Joint Intermediate use only 24-01-2018 View substance registered dossier
(3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran
619-599-0 915095-94-2 Active Intermediate Joint Intermediate use only 15-04-2020 View substance registered dossier
(3S)-3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one
626-470-2 5405-40-3 Cease Manufacture Full Individual Cease manufacture 05-07-2011 View substance registered dossier
(3S)-3-hydroxypyrrolidin-2-one
676-349-3 34368-52-0 Active Intermediate Individual Intermediate use only 12-11-2019 View substance registered dossier
(3S)-3-thiophen-2-ylsulfanylbutanoic acid
948-811-7 133359-80-5 Active Intermediate Joint Intermediate use only 23-10-2018 View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate
950-060-5 - Active Intermediate Joint Intermediate use only 15-01-2020 View substance registered dossier
(3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate
603-567-8 132335-47-8 Active Intermediate Individual Intermediate use only 08-10-2009 View substance registered dossier
(3S, 4R)-4-(4’-Fluorophenyl)-3-(3’, 4’-methylenedioxyphenyl)-Nmethylpiperidine
924-787-3 110429-36-2 Active Intermediate Joint Intermediate use only 08-03-2021 View substance registered dossier
(3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide
430-230-0 136522-17-3 Cease Manufacture NONS Individual Cease manufacture 13-09-2010 View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 Cease Manufacture Intermediate Individual Cease manufacture 29-10-2012 View substance registered dossier
(3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide
420-380-5 136465-81-1 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine
929-011-7 - Active Intermediate Joint Intermediate use only 20-04-2018 View substance registered dossier
(3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone
418-650-2 104872-06-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 16-05-2018 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 12-07-2013 View substance registered dossier
(3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one
608-748-5 324763-46-4 Active Intermediate Joint Intermediate use only 13-08-2014 View substance registered dossier
(3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4-
457-410-1 831213-72-0 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active Full Joint ≥ 0 to < 10 tonnes 16-04-2018 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3S,6E)-3,7,11-trimethyldodeca-6,10-dienal
810-298-1 194934-66-2 Active Full Joint ≥ 1 to < 10 tonnes 07-09-2020 View substance registered dossier
(3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone
444-350-6 133413-70-4 Active Intermediate Joint Intermediate use only 24-09-2019 View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
224-832-0 4511-42-6 Active Full Joint ≥ 1 000 to < 10 000 tonnes 26-07-2018 View substance registered dossier
(3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione
224-832-0 4511-42-6 Cease Manufacture Full Individual Cease manufacture 17-08-2015 View substance registered dossier
(3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate
430-510-2 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether
439-790-0 292605-05-1 Active Full Individual ≥ 0 to < 10 tonnes 18-01-2013 View substance registered dossier
(3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile
828-107-5 118316-12-4 Active Intermediate Joint Intermediate use only 05-09-2018 View substance registered dossier
(3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate)
840-627-4 1802323-89-2 Active Intermediate Joint Intermediate use only 26-06-2019 View substance registered dossier
(3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one
840-626-9 3798-17-2 Active Intermediate Joint Intermediate use only 26-06-2019 View substance registered dossier
(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid
228-475-1 6277-14-1 Active Full Joint ≥ 0 to < 10 tonnes 27-06-2019 View substance registered dossier
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate
250-567-5 31316-20-8 Active Intermediate Joint Intermediate use only 06-05-2015 View substance registered dossier
(4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid
813-651-8 1698890-39-9 Active Full Joint ≥ 1 to < 10 tonnes 14-05-2018 View substance registered dossier
(4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone
700-338-5 50372-61-7 Active Intermediate Joint Intermediate use only 05-10-2016 View substance registered dossier
(4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-(3,4-dichloro-phenyl)-3,4-dihydro-2H-naphthalen-1-ylidene)-methyl-amide
455-240-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid
410-430-4 117573-89-4 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
613-265-8 63590-64-7 Active Intermediate Joint Intermediate use only 25-07-2018 View substance registered dossier
(4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride
211-189-6 632-99-5 Active Full Joint ≥ 1 to < 10 tonnes 25-03-2018 View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester
927-587-4 872728-83-1 Active Intermediate Joint Intermediate use only 28-07-2016 View substance registered dossier
(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid
460-450-2 872728-82-0 Active Intermediate Joint Intermediate use only 17-05-2019 View substance registered dossier
(4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one
427-070-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-6) PEPTIDE
427-550-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide
423-840-3 14691-89-5 Active NONS Joint Tonnage data confidential 17-02-2012 View substance registered dossier
(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate
680-378-7 138624-11-0 Active Full Joint ≥ 1 to < 10 tonnes 02-02-2018 View substance registered dossier
(4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile
262-792-6 61437-85-2 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
(4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride
406-010-5 88918-84-7 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-butoxy-2,3-difluorophenyl)boronic acid
692-793-0 156487-12-6 Active Full Joint ≥ 1 to < 10 tonnes 16-05-2018 View substance registered dossier
(4-carboxybutyl)triphenylphosphonium bromide
241-782-5 17814-85-6 Active Intermediate Joint Intermediate use only 15-12-2015 View substance registered dossier
(4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone
695-300-7 1103738-30-2 Active Intermediate Joint Intermediate use only 24-11-2020 View substance registered dossier
(4-chlorophenyl)(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol
814-124-5 133545-64-9 Active Intermediate Joint Intermediate use only 10-05-2017 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 Active Intermediate Individual Intermediate use only 28-09-2010 View substance registered dossier
(4-chlorophenyl)hydrazine
214-029-3 1073-69-4 No longer Valid Intermediate Individual No longer valid 13-11-2013 View substance registered dossier
(4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid
826-639-2 1817776-86-5 Active Intermediate Joint Intermediate use only 20-07-2020 View substance registered dossier
(4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane
405-020-7 105024-66-6 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride
406-090-1 81880-96-8 No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(4-methoxybiphenyl-3-yl)hydrazine hydrochloride
924-885-6 - Active Intermediate Joint Intermediate use only 22-10-2012 View substance registered dossier
(4-Methoxyphenyl)diphenylsulfoniumnonaflate
435-570-3 - Active NONS Joint Tonnage data confidential 24-06-2009 View substance registered dossier
(4-methylphenyl)mesitylene sulfonate
407-530-5 67811-06-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-nitrophenyl)methanesulfonyl chloride
609-806-2 4025-75-6 Active Intermediate Individual Intermediate use only 18-12-2019 View substance registered dossier
(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
411-820-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-nonylphenoxy)acetic acid
221-486-2 3115-49-9 Active Full Joint ≥ 100 to < 1 000 tonnes 04-07-2014 View substance registered dossier
(4-phenylbutyl)phosphinic acid
420-450-5 86552-32-1 Active Intermediate Joint Intermediate use only 09-12-2013 View substance registered dossier
(4-pyridylmethyl)amine
223-092-6 3731-53-1 Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
(4-pyridylthio)acetyl chloride hydrochloride
248-348-4 27230-51-9 Active Intermediate Joint Intermediate use only 01-07-2020 View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride
479-480-2 17852-52-7 Active Full Joint ≥ 10 to < 100 tonnes 18-09-2017 View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride
479-480-2 17852-52-7 Active Intermediate Joint Intermediate use only 15-05-2018 View substance registered dossier
(4-Sulfamoylpheny)hydrazine monohydrochloride
479-480-2 17852-52-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-tert-butyl-2,6-dimethylphenyl)acetonitrile
284-183-4 84803-57-6 Active Intermediate Joint Intermediate use only 30-07-2015 View substance registered dossier
(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate
453-050-4 - Active NONS Individual Tonnage data confidential 04-02-2011 View substance registered dossier
(4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)
700-867-1 - Active Full Joint ≥ 1 to < 10 tonnes 02-07-2020 View substance registered dossier
(4aR*,8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride
439-750-2 183487-56-1 Active Full Joint ≥ 1 to < 10 tonnes 23-05-2018 View substance registered dossier
(4aR*,8aR*)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one
428-690-2 1668-86-6 Cease Manufacture NONS Individual Cease manufacture 23-11-2010 View substance registered dossier
(4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one
607-934-3 26441-40-7 Active Intermediate Joint Intermediate use only 29-04-2020 View substance registered dossier
(4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol
618-226-9 889652-22-6 Active Intermediate Joint Intermediate use only 05-05-2020 View substance registered dossier
(4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one
695-294-6 71136-60-2 Active Intermediate Joint Intermediate use only 30-04-2020 View substance registered dossier
(4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione
616-323-0 76318-69-9 Active Intermediate Joint Intermediate use only 14-06-2016 View substance registered dossier
(4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene
700-678-4 - Active Full Individual ≥ 100 to < 1 000 tonnes 05-05-2020 View substance registered dossier
(4aS-cis-)-6-benzyl-octahydropyrrolo[3.4-b]pyridine
425-930-8 151213-39-7 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4E)-4-(3,3,4-trimethylcyclopentylidene)butanal
- - Active Full Joint ≥ 0 to < 10 tonnes 05-03-2021 View substance registered dossier
(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one
939-401-9 - Active Full Joint ≥ 100 to < 1 000 tonnes 03-11-2020 View substance registered dossier
(4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one
941-406-6 1391712-50-7 Active Intermediate Joint Intermediate use only 08-01-2019 View substance registered dossier
(4E)-4-methyl-5-(4-methylphenyl)pent-4-enal
700-748-4 1226911-69-8 Active Full Joint ≥ 0 to < 10 tonnes 20-12-2017 View substance registered dossier
(4E)-5-cyclohexyl-2,4-dimethylpent-4-enal
947-579-4 1449104-34-0 Active Full Joint ≥ 1 to < 10 tonnes 08-12-2020 View substance registered dossier
(4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide
611-875-9 597563-86-5 Active Intermediate Joint Intermediate use only 28-10-2016 View substance registered dossier
(4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylenecyclohexane
944-221-9 1429469-15-7 Active Intermediate Joint Intermediate use only 24-02-2017 View substance registered dossier
(4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid
849-166-3 83841-00-3 Active Intermediate Joint Intermediate use only 18-05-2021 View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine
926-346-0 - Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
(4R)-4-methyl-1,3-dioxolan-2-one
437-320-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate
942-402-7 - Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Active Full Joint ≥ 1 to < 10 tonnes 18-08-2020 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
809-887-6 1206102-11-5 Active Intermediate Individual Intermediate use only 27-06-2019 View substance registered dossier
(4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
809-888-1 1051375-16-6 Active Intermediate Individual Intermediate use only 21-06-2017 View substance registered dossier
(4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6
700-052-0 60046-50-6 Active Intermediate Joint Intermediate use only 20-11-2019 View substance registered dossier
(4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
604-572-8 147128-77-6 Active Intermediate Joint Intermediate use only 06-09-2018 View substance registered dossier
(4S)-1-(tert-butoxycarbonyl)-4-(hydroxymethyl)-L-proline
812-482-7 1643468-66-9 Active Intermediate Individual Intermediate use only 17-05-2016 View substance registered dossier
(4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline
807-416-9 1378388-16-9 Active Intermediate Joint Intermediate use only 20-04-2018 View substance registered dossier
(4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline potassium salt
617-274-8 81938-42-3 Active Intermediate Individual Intermediate use only 09-10-2015 View substance registered dossier
(4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one
700-586-4 852212-81-8 Active Intermediate Individual Intermediate use only 10-05-2011 View substance registered dossier
(4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone
848-798-7 272778-12-8 Active Intermediate Joint Intermediate use only 15-06-2020 View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate
947-346-7 - Active Intermediate Individual Intermediate use only 25-03-2020 View substance registered dossier
(4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide
623-314-5 98674-86-3 Active Intermediate Joint Intermediate use only 26-03-2018 View substance registered dossier
(4S)-4-cyclohexyl-L-proline
600-406-3 103201-78-1 Active Intermediate Individual Intermediate use only 24-02-2010 View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide
807-123-6 154127-42-1 No longer Valid Intermediate Individual No longer valid 29-05-2018 View substance registered dossier
(4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide
807-123-6 154127-42-1 Active Intermediate Joint Intermediate use only 21-04-2021 View substance registered dossier
(4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate)
825-705-8 1235460-56-6 Active Intermediate Joint Intermediate use only 17-07-2018 View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)
940-053-5 - Active Intermediate Joint Intermediate use only 19-01-2017 View substance registered dossier
(4S,4aS,5aR,12aR)-11a-halo-4-(dialkylamino)-3,10,12a-trihydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-carbopolycyclyl-2-carboxamide hydrohalide
917-355-0 - Active Intermediate Individual Intermediate use only 21-05-2018 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
617-177-0 808-26-4 Active Intermediate Joint Intermediate use only 13-09-2018 View substance registered dossier
(4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide
811-441-0 1035654-66-0 Active Intermediate Joint Intermediate use only 27-11-2019 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride
611-780-2 59046-78-5 Active Intermediate Individual Intermediate use only 14-05-2018 View substance registered dossier
(4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid
618-775-4 916439-93-5 Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate
947-931-7 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
604-710-7 149934-21-4 Active Intermediate Joint Intermediate use only 12-08-2019 View substance registered dossier
(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)
925-915-0 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
442-870-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide,
824-717-0 403848-30-6 Active Intermediate Joint Intermediate use only 05-06-2018 View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide
947-800-4 - Active Intermediate Joint Intermediate use only 21-06-2018 View substance registered dossier
(4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid
443-440-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide
604-558-1 147086-83-7 Active Intermediate Joint Intermediate use only 09-03-2018 View substance registered dossier
(4Z)-3-ammoniomethyl-4-(methoxyimino)pyrrolidinium dimethanesulfonate
608-799-3 329181-36-4 Active Intermediate Individual Intermediate use only 10-06-2009 View substance registered dossier
(4Z)-hept-4-en-2-yl salicylate
700-488-1 873888-84-7 Active Full Individual ≥ 1 to < 10 tonnes 09-11-2010 View substance registered dossier
(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid
700-141-4 117570-53-3 Cease Manufacture Intermediate Individual Cease manufacture 22-06-2010 View substance registered dossier
(5-bromothiophen-2-yl)-phenylmethanone
608-584-4 31161-46-3 Active Intermediate Joint Intermediate use only 14-02-2018 View substance registered dossier
(5-chloro-2-methoxyphenyl)boronic acid
923-256-3 - Active Intermediate Individual Intermediate use only 27-04-2018 View substance registered dossier
(5-ethyl-1,3-dioxan-5-yl)methyl acrylate
266-380-7 66492-51-1 Active Full Joint ≥ 100 to < 1 000 tonnes 25-11-2020 View substance registered dossier
(5-ethyl-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
608-586-5 31167-05-2 Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate
604-437-3 144690-92-6 Active Intermediate Joint Intermediate use only 13-05-2013 View substance registered dossier
(5E)-3,5-dimethyloct-5-en-4-ol
947-581-5 2209852-19-5 Active Full Joint ≥ 1 to < 10 tonnes 13-03-2020 View substance registered dossier
(5E)-9-(Dichloromethylene)-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-one oxime
700-700-2 1369492-55-6 Active Intermediate Joint Intermediate use only 11-12-2020 View substance registered dossier
(5or8)-aminonaphthalene-2-sulphonic acid
257-269-4 51548-48-2 Active Full Joint ≥ 1 to < 10 tonnes 06-04-2018 View substance registered dossier
(5R)-5-(azidomethyl)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-1,3-oxazolidin-2-one
801-918-1 168828-84-0 Active Intermediate Individual Intermediate use only 18-01-2016 View substance registered dossier
(5R,6S)-allyl 6-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-7-oxo-3-(propylthio)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
820-260-6 93603-76-0 Active Intermediate Joint Intermediate use only 28-06-2018 View substance registered dossier
(5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose
815-962-4 1384242-56-1 Active Intermediate Joint Intermediate use only 04-12-2019 View substance registered dossier
(5Z)-5-(2-Methylpropylidene)imidazolidine-2,4-dione
700-726-4 - Active Intermediate Joint Intermediate use only 15-06-2018 View substance registered dossier
(5Z)-5-Benzylideneimidazolidine-2,4-dione
700-728-5 74805-60-0 Active Intermediate Joint Intermediate use only 24-04-2013 View substance registered dossier
(5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one
821-898-8 39931-87-8 Active Intermediate Joint Intermediate use only 07-05-2020 View substance registered dossier
(5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one
260-887-7 57664-96-7 Active Intermediate Joint Intermediate use only 28-04-2017 View substance registered dossier
(5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate
264-989-2 64643-76-1 Active Intermediate Individual Intermediate use only 03-12-2018 View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
251-561-5 33522-95-1 Active Intermediate Joint Intermediate use only 13-02-2019 View substance registered dossier
(5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
257-924-4 52446-24-9 Active Intermediate Joint Intermediate use only 16-03-2017 View substance registered dossier
(5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol
207-385-6 467-04-9 Active Intermediate Joint Intermediate use only 30-05-2018 View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
208-085-8 508-54-3 No longer Valid Intermediate Joint No longer valid 15-03-2018 View substance registered dossier
(5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one
282-186-5 84116-46-1 No longer Valid Intermediate Joint No longer valid 12-07-2019 View substance registered dossier
(5α)-Androsta-2,16-dien-17-yl acetate
610-545-1 50588-42-6 Cease Manufacture Full Individual Cease manufacture 21-05-2015 View substance registered dossier
(5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride
245-549-9 23277-43-2 Active Intermediate Joint Intermediate use only 19-06-2017 View substance registered dossier
(6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate
402-060-7 108225-03-2 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(6-alpha,11-beta,16-alpha,17-alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-androsta-1,4-diene-17-carbothioic acid
617-081-9 80473-92-3 Active Full Joint ≥ 1 to < 10 tonnes 21-11-2016 View substance registered dossier
(6-alpha,11-beta,16-alpha,17-alpha)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid
617-084-5 80474-45-9 Active Full Joint ≥ 1 to < 10 tonnes 20-12-2016 View substance registered dossier
(6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride
842-055-0 2356133-42-9 Active Intermediate Individual Intermediate use only 21-08-2019 View substance registered dossier
(6-aminohexyl)carbamic acid
205-581-6 143-06-6 Active Full Joint ≥ 100 to < 1 000 tonnes 02-10-2018 View substance registered dossier
(6-Bromo-2-pyridinyl)(4-methylphenyl)methanone
618-079-0 87848-95-1 No longer Valid Full Individual No longer valid 25-10-2019 View substance registered dossier
(6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate
938-716-9 - No longer Valid Intermediate Individual No longer valid 04-02-2013 View substance registered dossier
(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid
921-925-4 - Active Intermediate Joint Intermediate use only 12-05-2017 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Active Intermediate Individual Intermediate use only 18-12-2013 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-11-2014 View substance registered dossier
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt
439-350-8 - Cease Manufacture NONS Individual Cease manufacture 22-12-2010 View substance registered dossier
(6R,7R)-7-[((2Z)-2-[({2-[(1,1-dimethylethyl)oxy]-1,1-dimethyl-2-oxoethyl}oxy)imino]-2-{2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl}acetyl)amino]-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
617-560-2 84377-83-3 No longer Valid Full Joint No longer valid 15-11-2018 View substance registered dossier
(6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride
827-945-9 107648-80-6 Active Intermediate Joint Intermediate use only 21-09-2018 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride
600-507-2 103980-44-5 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester
609-461-8 376653-36-0 Active Full Joint ≥ 1 to < 10 tonnes 30-07-2018 View substance registered dossier
(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester
609-463-9 376653-41-7 Active Full Joint ≥ 1 to < 10 tonnes 30-07-2018 View substance registered dossier
(6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide
606-382-0 197897-11-3 Cease Manufacture Intermediate Individual Cease manufacture 20-04-2018 View substance registered dossier
(6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
617-065-1 80370-59-8 Cease Manufacture Intermediate Joint Cease manufacture 03-04-2018 View substance registered dossier
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid
438-350-5 79349-82-9 Active NONS Individual Tonnage data confidential 20-12-2010 View substance registered dossier
(6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid
438-350-5 79349-82-9 Active Intermediate Joint Intermediate use only 21-12-2017 View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
700-301-3 69739-16-8 Cease Manufacture Intermediate Individual Cease manufacture 04-06-2009 View substance registered dossier
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
600-349-4 102772-66-7 Active Intermediate Joint Intermediate use only 08-05-2018 View substance registered dossier
(6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine
605-428-7 16614-59-8 Active Intermediate Joint Intermediate use only 18-12-2020 View substance registered dossier
(6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide
423-260-0 100988-63-4 Cease Manufacture NONS Individual Cease manufacture 29-10-2012 View substance registered dossier
(6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
239-787-2 15690-38-7 Active Intermediate Joint Intermediate use only 19-12-2018 View substance registered dossier
(6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid
403-690-5 111298-82-9 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
250-099-1 30246-33-4 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
619-847-8 111298-82-9 Cease Manufacture Intermediate Individual Cease manufacture 26-03-2009 View substance registered dossier
(6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
258-907-4 53994-69-7 Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
(6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
244-870-1 22252-43-3 Active Intermediate Joint Intermediate use only 16-12-2019 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Active Intermediate Joint Intermediate use only 10-07-2019 View substance registered dossier
(6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
261-491-7 58909-56-1 Cease Manufacture Full Joint Cease manufacture 03-05-2018 View substance registered dossier
(6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde
482-190-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate
949-377-1 - Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
(6S)-3,10-dibromo-6-phenylindolo[1,2-c][1,3]benzoxazine
813-156-7 1392102-38-3 Active Intermediate Individual Intermediate use only 26-09-2016 View substance registered dossier
(6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1)
605-420-3 165950-84-5 Active Full Joint ≥ 1 to < 10 tonnes 26-11-2020 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active Intermediate Joint Intermediate use only 13-11-2017 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1)
603-080-0 125572-93-2 Active Full Joint ≥ 1 to < 10 tonnes 17-12-2020 View substance registered dossier
(6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydroindolo[1,2-c][1,3]benzoxazine
813-155-1 1585969-16-9 Active Intermediate Individual Intermediate use only 21-09-2016 View substance registered dossier
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
435-680-1 - Cease Manufacture Full Individual Cease manufacture 17-05-2018 View substance registered dossier
(6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
615-123-0 7055-53-0 Active Intermediate Joint Intermediate use only 18-09-2017 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
[Confidential] - - - (3R,4S,5S,6R,7R,9R,10Z,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione 10-oxime 603-883-6 134931-01-4 - View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active (3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 918-279-0 - - View substance registered dossier
Huvepharma Italia s.r.l. Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy Italy Active (3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10(3H)-one 700-290-5 63968-64-9 2009; 2010; 2012 View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (3R,5R)-tert-Butyl 7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate 603-817-6 134395-00-9 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (3R,5Z)-3-METHYL-5-CYCLOPENTADECEN-1-ONE 851-742-4 464207-51-0 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione 603-436-5 13076-17-0 - View substance registered dossier
PURAC Biochem Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active (3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione 603-436-5 13076-17-0 2011; 2015 View substance registered dossier
Total Corbion PLA bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active (3R,6R)-3,6-dimethyl-1,4-dioxane-2,5-dione 603-436-5 13076-17-0 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aR)-3-tert-butyl-1,5-dioxodihydro-1H-pyrrolo[1,2-c][1,3]oxazole-7a(5H)-carbaldehyde 812-036-1 1214741-19-1 2019 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione 942-823-6 - 2019 View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aS)-3-tert-butyldihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione 810-392-2 171284-84-7 2019 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate 228-502-7 6283-74-5 - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active (3R-trans)-dihydro-2,5-dioxofuran-3,4-diyl diacetate 228-502-7 6283-74-5 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
- - - - (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
[Confidential] - - - (3S)-2-{N-[1-ethoxy-1-oxo-4-phenylbutan-2-yl]-substituted}-heteropolycyclic-3-carboxylic acid hydrochloride 919-408-3 - - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S)-3,7-Dimethyl-1-octanol 814-059-2 68680-98-8 - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (3S)-3,7-dimethylocta-1,6-dien-1-yl acetate 946-529-9 1439355-19-7 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran 619-599-0 915095-94-2 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran 619-599-0 915095-94-2 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (3S)-3-[4-(2-chloro-5-iodobenzyl)phenoxy]tetrahydrofuran 619-599-0 915095-94-2 2019 View substance registered dossier
TÜV SÜD Industrie Service GmbH IS-USR-MUC Westendstr. 199 80686 Munich Germany Germany Cease Manufacture (3S)-3-hydroxy-4,4-dimethyldihydrofuran-2(3H)-one 626-470-2 5405-40-3 2015 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (3S)-3-hydroxypyrrolidin-2-one 676-349-3 34368-52-0 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (3S)-3-thiophen-2-ylsulfanylbutanoic acid 948-811-7 133359-80-5 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate 950-060-5 - - View substance registered dossier
Saneca Pharmaceuticals a.s. Nitrianska 100 92027 Hlohovec Slovakia Slovakia Active (3S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate 603-567-8 132335-47-8 2009 View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active (3S, 4R)-4-(4’-Fluorophenyl)-3-(3’, 4’-methylenedioxyphenyl)-Nmethylpiperidine 924-787-3 110429-36-2 2021 View substance registered dossier
CHEMI S.p.A. Via dei lavoratori, 54 20092 Cinisello balsamo Lombardia Italy Italy Active (3S, 4R)-4-(4’-Fluorophenyl)-3-(3’, 4’-methylenedioxyphenyl)-Nmethylpiperidine 924-787-3 110429-36-2 - View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture (3S,4aS,8aS)-2-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-N-tert-butyldecahydroisoquinoline-3-carboxamide 430-230-0 136522-17-3 2020 View substance registered dossier
Roche Ireland Limited Clarehill . Clarecastle Ireland Ireland Cease Manufacture (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3S,4aS,8aS)-N-tert-butyldecahydro-3-isoquinolinecarboxamide 420-380-5 136465-81-1 - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine 929-011-7 - - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Austrian competent national authority. - - Active (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (3S,4S)-3-hexyl-4-[(R)-2-hydroxytridecyl]-2-oxetanone 418-650-2 104872-06-2 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - 2011; 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
[Confidential] - - - (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one 608-748-5 324763-46-4 2014 View substance registered dossier
Novartis Grimsby Limited Moody Lane, Pyewipe DN31 2SR Grimsby N.E. Lincolnshire United Kingdom United Kingdom No longer Valid (3S,5S)-5-[(1S,3S)-1-azido-3-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-4-methylpentyl]-3-(propan-2-yl)oxolan-2-one 608-748-5 324763-46-4 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- 457-410-1 831213-72-0 - View substance registered dossier
- - - - (3S,5S,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- and (3S,5R,6S,9R)-6-isopropyl-3,9-dimethyl-1,4- 457-410-1 831213-72-0 - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - 2018 View substance registered dossier
- - - - (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - - View substance registered dossier
TAKASAGO TEPL-Importer 12 rue Torricelli 75017 Paris France France Active (3S,6E)-3,7,11-trimethyldodeca-6,10-dienal 810-298-1 194934-66-2 2020 View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S,6E)-3,7,11-trimethyldodeca-6,10-dienal 810-298-1 194934-66-2 - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone 444-350-6 133413-70-4 2010; 2018 View substance registered dossier
Bayer Animal Health GmbH Alfred Nobel Straße 50 40789 Monheim Germany Germany Active (3S,6R,9S,12R,15S,18R,21S,24R)-6,18-dibenzyl-3,9,15,21-tetraisobutyl-4,10,12,16,22,24-hexamethyl-1,7,13,19-tetraoxa-4,10,16,22-tetraazacyclo-tetracosane-2,5,8,11,14,17,20,23-octaone 444-350-6 133413-70-4 - View substance registered dossier
Total Corbion PLA bv Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 - View substance registered dossier
PURAC Biochem Arkelsedijk 46 4206AC Gorinchem Netherlands Netherlands Active (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 2011; 2015 View substance registered dossier
Santrol Europe ApS Aagade 103 Pjedsted 7000 Fredericia Denmark Denmark Cease Manufacture (3S-cis)-3,6-dimethyl-1,4-dioxane-2,5-dione 224-832-0 4511-42-6 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate 430-510-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (3S-trans)-phenyl-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinecarboxylate 430-510-2 - - View substance registered dossier
IFF Benicarlo, S.L. Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain Spain Active (3Z)-hex-3-en-1-yl 2-methylprop-2-en-1-yl ether 439-790-0 292605-05-1 2013 View substance registered dossier
Farmabios Spa Via Pavia, 1 27027 Gropello Cairoli PV Italy Italy Active (3α,5β,7β)-3,7-Dihydroxy-24-norcholane-23-nitrile 828-107-5 118316-12-4 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (3β)-17-(1,1,1-trifluoromethanesulfonate)-Androsta-5,16-diene-3,17-diol, 3-(2,2,2-trifluoroacetate) 840-627-4 1802323-89-2 - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (3β)-3-[(2,2,2-trifluoroacetyl)oxy]-Androst-5-en-17-one 840-626-9 3798-17-2 - View substance registered dossier
Indena S.p.A. Viale Ortles, 12 20139 Milan Italy Italy Active (3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid 228-475-1 6277-14-1 2019 View substance registered dossier
DSM Nutritional Products France SAS 1 boulevard d'Alsace F-68128 Village-Neuf France France Active (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-yl butyrate 250-567-5 31316-20-8 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (4'-methyl-3-fluoro[1,1'-biphenyl]-4-yl)-boronic acid 813-651-8 1698890-39-9 - View substance registered dossier
UNION QUIMICO FARMACÉUTICA S.A. Mallorca 262 08008 Barcelona Barcelona Spain Spain Active (4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone 700-338-5 50372-61-7 2016 View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (4,5-dibromo-1H-pyrrol-2-yl)(phenyl)methanone 700-338-5 50372-61-7 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 - View substance registered dossier
ELKEM SILICONES FRANCE S.A.S. Immeuble DANICA 21, Avenue Georges Pompidou 69003 Lyon France France Active (4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-(1-methylethyl)phenyl)-(4-methylphenyl)iodonium tetrakis(pentafluorophenyl)borate (1-) 422-960-3 178233-72-2 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4-(3,4-dichloro-phenyl)-3,4-dihydro-2H-naphthalen-1-ylidene)-methyl-amide 455-240-2 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-(4-(4-dimethylaminobenzyliden-1-yl)-3-methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid 410-430-4 117573-89-4 - View substance registered dossier
CU Chemie Uetikon GmbH Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany Germany Active (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone 613-265-8 63590-64-7 2018 View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active (4-(4-aminophenyl)(4-iminocyclohexa-2,5-dienylidene)methyl)-2-methylaniline hydrochloride 211-189-6 632-99-5 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester 927-587-4 872728-83-1 2016 View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-phenylamino)-acetic acid ethyl ester 927-587-4 872728-83-1 - View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 2012; 2019 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 2013; 2016 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazole-3-yl)phenylamino)acetic acid 460-450-2 872728-82-0 2012; 2014; 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one 427-070-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (4-6) PEPTIDE 427-550-8 - - View substance registered dossier
United Initiators GmbH Dr. Gustav-Adolph-Str. 3 D-82049 Pullach Bavaria Germany Germany Active (4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide 423-840-3 14691-89-5 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (4-acetamido-2,2,6,6-tetramethyl-1-piperidinyl)oxidanyl; N-(2,2,6,6-tetramethyl-1-oxylpiperidin-4-yl)acetamide 423-840-3 14691-89-5 2012 View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate 680-378-7 138624-11-0 - View substance registered dossier
Globalquimia, S.L.U. Avenida Diagonal, 519, 1º 1ª 08029 Barcelona Spain Spain Spain Active (4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile 262-792-6 61437-85-2 - View substance registered dossier
Menadiona SL Pol Ind Mas Puigvert, Ctra Nacional II Km 680, 5 08389 Palafolls Barcelona Spain Spain Active (4-amino-2-chloro-5-methylphenyl)(4-chlorophenyl)acetonitrile 262-792-6 61437-85-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride 406-010-5 88918-84-7 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-aminophenyl)-N-methylmethylenesulfonamide hydrochloride 406-010-5 88918-84-7 - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (4-butoxy-2,3-difluorophenyl)boronic acid 692-793-0 156487-12-6 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (4-carboxybutyl)triphenylphosphonium bromide 241-782-5 17814-85-6 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone 695-300-7 1103738-30-2 2020 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4-Chloro-3-(4-ethoxybenzyl)phenyl)((3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanone 695-300-7 1103738-30-2 - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active (4-chlorophenyl)(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol 814-124-5 133545-64-9 - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2010 View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (4-chlorophenyl)hydrazine 214-029-3 1073-69-4 2018 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (4-cyclopropyl-6-methyl-pyrimidin-5-yl)boronic acid 826-639-2 1817776-86-5 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (4-ethoxyphenyl)(3-(4-fluoro-3-phenoxyphenyl)propyl)dimethylsilane 405-020-7 105024-66-6 - View substance registered dossier
Fine Organics Limited Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom United Kingdom No longer Valid (4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride 406-090-1 81880-96-8 2021 View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active (4-methoxybiphenyl-3-yl)hydrazine hydrochloride 924-885-6 - - View substance registered dossier
- - - - (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-methylphenyl)mesitylene sulfonate 407-530-5 67811-06-7 - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (4-nitrophenyl)methanesulfonyl chloride 609-806-2 4025-75-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] 411-820-7 - - View substance registered dossier
BASF Performance Products France SA Rue de la Chapelle 28 68330 Huningue France France Cease Manufacture (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 2015 View substance registered dossier
BASF Lampertheim GmbH Chemiestrasse 22 68619 Lampertheim Germany Germany Active (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 2014 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (4-nonylphenoxy)acetic acid 221-486-2 3115-49-9 - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (4-phenylbutyl)phosphinic acid 420-450-5 86552-32-1 2017 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-phenylbutyl)phosphinic acid 420-450-5 86552-32-1 - View substance registered dossier
INTEROR 49, rue d'Ostende F-62100 CALAIS France France Active (4-pyridylmethyl)amine 223-092-6 3731-53-1 - View substance registered dossier
Intertek Italia SpA_ITAzo Via Miglioli 2/A 20063 CERNUSCO SUL NAVIGLIO Milano Italy Italy Active (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 2021 View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Active (4-pyridylthio)acetyl chloride hydrochloride 248-348-4 27230-51-9 - View substance registered dossier
[Confidential] - - - (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Siemsgluss Ibérica, S.A. Pol. Ind. Sant Antoni, parcela 6, nave 2 08620 Sant Vicenç dels Horts Barcelona Spain Spain Active (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Biesterfeld Spezialchemie GmbH Ferdinandstr. 41 20095 Hamburg Germany Germany Active (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Excella GmbH & Co. KG Nuernberger Str. 12 90537 Feucht Germany Germany Active (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 2018 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (4-Sulfamoylpheny)hydrazine monohydrochloride 479-480-2 17852-52-7 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (4-tert-butyl-2,6-dimethylphenyl)acetonitrile 284-183-4 84803-57-6 - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active (4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate 453-050-4 - 2011 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - 2020 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - 2020 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (4aR*,8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride 439-750-2 183487-56-1 2010; 2012; 2018 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (4aR*,8aR*)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-benzofuro[3a,3,2-ef][2]benzazepin-6-one 428-690-2 1668-86-6 2019 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,7aS,8aS,8bR,8cR)-2-methoxy-4a,6a-dimethyl-4,4a,4b,5,6,6a,7a,8,8a,8b,8c,9-dodecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7(3H)-one 607-934-3 26441-40-7 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,7S,7aS,8aS,8bR,8cR)-7-[2-(1,3-dioxolan-2-yl)ethyl]-2-methoxy-4a,6a-dimethyl-3,4,4a,4b,5,6,6a,7,7a,8,8a,8b,8c,9-tetradecahydrocyclopropa[4,5]cyclopenta[1,2-a]phenanthren-7-ol 618-226-9 889652-22-6 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR)-5`-methoxy-4a,6a-dimethyl-4,4`,4a,4b,5`,6,6a,7a,8,8a,8b,8c-dodecahydro-3H,3`H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]phenathrene-7,2`-furan]-2(5H)-one 695-294-6 71136-60-2 2020 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (4aR,4bS,6aS,9aS,9bR,11aR)-4a,6a-Dimethyltetradecahydro-1H-indeno[5,4-f]quinoline-2,7-dione 616-323-0 76318-69-9 - View substance registered dossier
Covance Clinical Development SA 163 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain Spain Active (4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 700-678-4 - 2019; 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (4aS-cis-)-6-benzyl-octahydropyrrolo[3.4-b]pyridine 425-930-8 151213-39-7 - View substance registered dossier
V. MANE FILS 620 route de Grasse 06620 Le Bar sur Loup France France Active (4E)-4-(3,3,4-trimethylcyclopentylidene)butanal - - - View substance registered dossier
Solenis Belgium B.V.B.A. Industrieweg 15 3583 Beringen Belgium Belgium Cease Manufacture (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2016 View substance registered dossier
Mare S.p.A. Via Verdi No. 3 20002 Ossona Fraz. Asmonte Italy Italy Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2020 View substance registered dossier
Solenis Netherlands B.V. Pesetastraat 62 2991 XT Barendrecht Netherlands Netherlands Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active (4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one 941-406-6 1391712-50-7 - View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (4E)-4-[3-(2,5-dichloro-4,6-dimethylpyridin-3-yl)-2H-1,2,4-oxadiazol-5-ylidene]-2-methoxy-6-nitrocyclohexa-2,5-dien-1-one 941-406-6 1391712-50-7 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (4E)-4-methyl-5-(4-methylphenyl)pent-4-enal 700-748-4 1226911-69-8 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (4E)-5-cyclohexyl-2,4-dimethylpent-4-enal 947-579-4 1449104-34-0 2020 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (4E)-N-hydroxy-1,2-benzoxathiin-4(3H)-imine 2,2-dioxide 611-875-9 597563-86-5 - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (4R)-2-(1-butoxyethoxy)-4-isopropyl-1-methylenecyclohexane 944-221-9 1429469-15-7 - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa - Attiki Greece Greece Active (4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid 849-166-3 83841-00-3 2021 View substance registered dossier
CABB Oy Kemirantie 1 FI-67701 Kokkola Finland Finland Active (4R)-2-oxo-1,3-oxazolidine-4-carboxylic acid 849-166-3 83841-00-3 2020 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine 926-346-0 - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - - View substance registered dossier
EXPANSIA Route d'Avignon BP 6 30390 ARAMON France France Active (4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate 942-402-7 - - View substance registered dossier
PCAS 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France France Active (4R)-6-amino-N,N,4-trimethyl-1,4-dihydro-1,3,5-triazin-2-aminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate 942-402-7 - 2018 View substance registered dossier
Visolis, B.V. Urmonderbaan 22 6167 RD Geleen Netherlands Netherlands Active (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
- - - - (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (4R,12aS)-7-Benzyloxy-N-[(2,4-difluorophenyl)methyl]-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 809-887-6 1206102-11-5 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 809-888-1 1051375-16-6 - View substance registered dossier
[Confidential] - - - (4R,6R)-4-Hydroxy-2,2,6-trimethylcyclohexanone / 60046-50-6 700-052-0 60046-50-6 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4R,6S)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol 604-572-8 147128-77-6 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4S)-1-(tert-butoxycarbonyl)-4-(hydroxymethyl)-L-proline 812-482-7 1643468-66-9 - View substance registered dossier
Gilead Sciences Ireland UC IDA Business &Technology Park Carrigtohill Cork Cork Ireland Ireland Active (4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline 807-416-9 1378388-16-9 - View substance registered dossier
Derivados Químicos S.A. Camino Viejo del Pliego s/n 30820 Alcantarilla Murcia Spain Spain Active (4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline 807-416-9 1378388-16-9 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4S)-1-(tert-butoxycarbonyl)-4-(methoxymethyl)-L-proline 807-416-9 1378388-16-9 - View substance registered dossier
LusoChimica S.p.A. Via Giotto, 9 23871 Lomagna (Lecco) Italy Italy Active (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-(phenylthio)-L-proline potassium salt 617-274-8 81938-42-3 - View substance registered dossier
QUIMICA SINTETICA, S.A. C/ Dulcinea, s/n 28805 Alcalá de Henares Madrid Spain Spain Active (4S)-2-(4-bromophenyl)-4-isopropyl-3-pentanoyl-1,3-oxazolidin-5-one 700-586-4 852212-81-8 - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active (4S)-3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-2-oxazolidinone 848-798-7 272778-12-8 2020 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active (4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate 947-346-7 - 2020 View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (4S)-4-(2-Chlorophenyl)-2-hydroxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide 623-314-5 98674-86-3 - View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active (4S)-4-cyclohexyl-L-proline 600-406-3 103201-78-1 - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid (4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide 807-123-6 154127-42-1 2021 View substance registered dossier
ChemLeader 11 Fine & Performance Chemicals Ltd Długosza 67 43-188 Orzesze Poland Poland Active (4S)-4-hydroxy-2-(3-methoxypropyl)-1,1-dioxo-3,4,4a,7a-tetrahydrothieno[3,2-e]thiazine-6-sulfonamide 807-123-6 154127-42-1 - View substance registered dossier
CHEMO BIOSYNTHESIS SRL VIALE ISONZO, 8 20135 MILANO Italy Italy Active (4S,4aR,5aR,6R,6aR,6bS,7S,9aS,11aS,11bR)-6-hydroxy-9a,11b-dimethyl-9-oxohexadeca hydrocyclopenta[1,2]phenanthro[8a,9-b]oxirene-4,7-diyl bis(2,2-dimethylpropanoate) 825-705-8 1235460-56-6 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Hovione Limited Loughbeg not available Ringaskiddy County Cork Ireland Ireland Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
[Confidential] - - - (4S,4aS,5aR,12aR)-11a-halo-4-(dialkylamino)-3,10,12a-trihydroxy-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-carbopolycyclyl-2-carboxamide hydrohalide 917-355-0 - - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 617-177-0 808-26-4 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aR)-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-7-[[methoxy(methyl)amino]methyl]-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide 811-441-0 1035654-66-0 - View substance registered dossier
[Confidential] - - - (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide dihydrochloride 611-780-2 59046-78-5 - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; 4-chlorobenzene-1-sulfonic acid 618-775-4 916439-93-5 - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate 947-931-7 - - View substance registered dossier
Curia Italy S.r.l. VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy Italy Active (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1) 604-710-7 149934-21-4 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1) 604-710-7 149934-21-4 2013; 2018; 2019 View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid) 925-915-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - - View substance registered dossier
- - - - (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonyl chloride, 4-(acetylethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, 824-717-0 403848-30-6 - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide 947-800-4 - - View substance registered dossier
Sanofi S.R.L. Viale Luigi Bodio n. 37/b 20158 Milano Italy Italy Active (4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid 443-440-2 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (4S-trans)-N-(5,6-diidro-6-metil-7,7-diossido-4Htieno[2,3-b]tiopiran-4-il)-acetammide 604-558-1 147086-83-7 - View substance registered dossier
PROCOS SpA via Matteotti 249 28062 Cameri Piemonte Italy Italy Active (4Z)-3-ammoniomethyl-4-(methoxyimino)pyrrolidinium dimethanesulfonate 608-799-3 329181-36-4 - View substance registered dossier
Givaudan France SAS - OR1 55, Rue de la voie des Bans CS500024 95102 Argenteuil Cedex France France Active (4Z)-hept-4-en-2-yl salicylate 700-488-1 873888-84-7 - View substance registered dossier
Novartis Ringaskiddy Limited . . Ringaskiddy County Cork Ireland Ireland Cease Manufacture (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid 700-141-4 117570-53-3 2015 View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (5-bromothiophen-2-yl)-phenylmethanone 608-584-4 31161-46-3 - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (5-chloro-2-methoxyphenyl)boronic acid 923-256-3 - - View substance registered dossier
Miwon Europe GmbH Zeppelinstraße 26 D-47638 Straelen Germany Germany Active (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 - View substance registered dossier
COVANCE CLINICAL DEVELOPMENT SA 119 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain Spain Active (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 - View substance registered dossier
ARKEMA PHOTOCURES 420 rue d'Estienne d'Orves 92700 Colombes France France Active (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 - View substance registered dossier
IGM Resins Ltd c/o Baldwins, Wynyard Park House Wynyard Avenue TS22 5TB Wynyard Durham United Kingdom United Kingdom No longer Valid (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 2021 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 2015 View substance registered dossier
IGM Resins B.V. Gompenstraat 49 5145 RA Waalwijk Netherlands Netherlands Active (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 2020 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 2018 View substance registered dossier
RAHN NL B.V. (30) Westplein 11 3016BM Rotterdam Netherlands Netherlands Active (5-ethyl-1,3-dioxan-5-yl)methyl acrylate 266-380-7 66492-51-1 - View substance registered dossier
FERRANIA CHEMICALS S.R.L. Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy Italy Active (5-ethyl-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane 608-586-5 31167-05-2 2019 View substance registered dossier
CHINOIN Pharmaceutical and Chemical Works Private Co. Ltd. TO Utca 1-5 POB 110 1325 BUDAPEST Ujpest Hungary Hungary Active (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate 604-437-3 144690-92-6 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (5E)-3,5-dimethyloct-5-en-4-ol 947-581-5 2209852-19-5 - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active (5E)-9-(Dichloromethylene)-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-one oxime 700-700-2 1369492-55-6 2014; 2018; 2020 View substance registered dossier
[Confidential] - - - (5E)-9-(Dichloromethylene)-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-one oxime 700-700-2 1369492-55-6 - View substance registered dossier
Global Product Compliance (Europe) AB IDEON, Beta 5, Scheelevägen 17 22363 Lund Sweden Sweden Active (5or8)-aminonaphthalene-2-sulphonic acid 257-269-4 51548-48-2 - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active (5or8)-aminonaphthalene-2-sulphonic acid 257-269-4 51548-48-2 - View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (5R)-5-(azidomethyl)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-1,3-oxazolidin-2-one 801-918-1 168828-84-0 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (5R,6S)-allyl 6-((R)-1-(tert-butyldimethylsilyloxy)ethyl)-7-oxo-3-(propylthio)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 820-260-6 93603-76-0 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose 815-962-4 1384242-56-1 - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (5S)-1,2,3,4-tetra-O-acetyl-5-[4-chloro-3-(4-ethoxybenzyl)phenyl]-beta-L-xylopyranose 815-962-4 1384242-56-1 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-(2-Methylpropylidene)imidazolidine-2,4-dione 700-726-4 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-(2-Methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2017 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-Benzylideneimidazolidine-2,4-dione 700-728-5 74805-60-0 - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-Benzylideneimidazolidine-2,4-dione 700-728-5 74805-60-0 2013 View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (5´R,8´S,10´R,13´S,14´S)-13´-methyl-1´,2´,6´,7´8´,12´,13´,14´,15´,16´-decahydro-17´H-spiro[1,3-dioxolane-2,3´-[5,10]epoxycyclopenta[a]phenantren]-17´-one 821-898-8 39931-87-8 2020 View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-14-hydroxy-3-methoxymorphinan-6-one 260-887-7 57664-96-7 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (5α)-4,5-epoxy-17-methyl-6-oxomorphinan-3,14-diyl diacetate 264-989-2 64643-76-1 - View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 2021 View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one 251-561-5 33522-95-1 - View substance registered dossier
[Confidential] - - - (5α)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride 257-924-4 52446-24-9 - View substance registered dossier
HH Compliance The Rubicon Centre CIT Campus , Bishopstown T12 Y275 Cork Co Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
Alcaliber S.A. Ventalomar 1 45007 Toledo Toledo Spain Spain Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
HH Compliance Ltd Rubicon Building, CIT Campus Bishopstown None Cork Ireland Ireland Active (5α)-6,7,8,14-tetradehydro-4,5-epoxy-6-methoxy-17-methylmorphinan-3-ol 207-385-6 467-04-9 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-7,8-didehydro-4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one 208-085-8 508-54-3 2021 View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (5α)-7,8-didehydro-4,5-epoxy-3,14-dihydroxymorphinan-6-one 282-186-5 84116-46-1 2021 View substance registered dossier
Aspen Oss BV Kloosterstraat 6 5349 AB Oss Netherlands Netherlands Cease Manufacture (5α)-Androsta-2,16-dien-17-yl acetate 610-545-1 50588-42-6 2019 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (5α,6α)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol hydrochloride 245-549-9 23277-43-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Norwegian competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Cease Manufacture (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 2016 View substance registered dossier
Archroma Germany GmbH Kasteler Str. 45 65203 Wiesbaden Germany Germany Cease Manufacture (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Portuguese competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Swedish competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 - View substance registered dossier
Archroma UK, Ltd 1 Bartholomew Lane EC2N 2AX London United Kingdom United Kingdom No longer Valid (6-(4-hydroxy-3-(2-methoxyphenylazo)-2-sulfonato-7-naphthylamino)-1,3,5-triazin-2,4-diyl)bis[(amino-1-methylethyl)ammonium] formate 402-060-7 108225-03-2 2021 View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Active (6-alpha,11-beta,16-alpha,17-alpha)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-androsta-1,4-diene-17-carbothioic acid 617-081-9 80473-92-3 - View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Active (6-alpha,11-beta,16-alpha,17-alpha)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid 617-084-5 80474-45-9 - View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active (6-amino-2-pyridyl)-(1-methyl-4-piperidyl)methanone;dihydrate;dihydrochloride 842-055-0 2356133-42-9 - View substance registered dossier
W. L. Gore & Associates GmbH Hermann-Oberth-Strasse 22 85640 Putzbrunn Germany Germany Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
[Confidential] - - - (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
IB CHEM S.R.L. VIA E. FERMI 21E 72100 BRINDISI Italy Italy Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 2018 View substance registered dossier
Unimatec Chemicals Europe Im Technologiepark 1 69469 Weinheim Germany Germany Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
C.S.B. GmbH Duesseldorfer Str.113 47809 Krefeld Germany Germany Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
Chemical Inspection & Regulation Service Limited Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland Ireland Active (6-aminohexyl)carbamic acid 205-581-6 143-06-6 - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (6-Bromo-2-pyridinyl)(4-methylphenyl)methanone 618-079-0 87848-95-1 2021 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid (6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate 938-716-9 - 2021 View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active (6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid 921-925-4 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - - View substance registered dossier
Corden Pharma Latina S.p.A. Via del Murillo Km 2, 800 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - 2017 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt 439-350-8 - 2021 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid (6R,7R)-7-[((2Z)-2-[({2-[(1,1-dimethylethyl)oxy]-1,1-dimethyl-2-oxoethyl}oxy)imino]-2-{2-[(triphenylmethyl)amino]-1,3-thiazol-4-yl}acetyl)amino]-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 617-560-2 84377-83-3 2021 View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (6R,7R)-7-[[(2Z)-(2-Aminothiazol-4-yl)(methoxy-imino)acetyl]amino]-3-[1-methylpyrrolidinio)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate dihydrochloride 827-945-9 107648-80-6 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(furan-2-carbonylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrochloride 600-507-2 103980-44-5 2021 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acethyl]amino]-3-(hydroxymethyl)-8-oxo-5thia-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid diphenylmethyl ester 609-461-8 376653-36-0 2018 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(triphenylmethoxy)imino]acetyl]amino]-3-[(E)-[(3'R)-1'-[(1,1-dimethylethoxy)carbonyl]-2-oxo-[1,3'-bipyrrolidin]-3-ylidene]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester 609-463-9 376653-41-7 2018 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-(5H-imidazo[1,2-b]pyridazin-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydroiodide 606-382-0 197897-11-3 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-amino-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 617-065-1 80370-59-8 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Active (6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid 438-350-5 79349-82-9 2010 View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (6R,7R)-7-Amino-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4,2,0]oct-2-ene-2-carboxylic acid 438-350-5 79349-82-9 2012; 2017 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 700-301-3 69739-16-8 2021 View substance registered dossier
FRESENIUS KABI iPSUM s.r.l. Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy Italy Active (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1-tert-butoxy-2-methyl-1-oxopropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 600-349-4 102772-66-7 - View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active (6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine 605-428-7 16614-59-8 2020 View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany Germany Active (6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine 605-428-7 16614-59-8 - View substance registered dossier
Macfarlan Smith Limited Wheatfield Road EH11 2QA Edinburgh United Kingdom United Kingdom No longer Valid (6R,7R,14S)-7-[(2S)-2-hydroxy-3,3-dimethylbut-2-yl]-6,7,8,14-tetrahydro-6,14-ethano-17-northebaine 605-428-7 16614-59-8 2021 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-1-((7-ammonio-2-carboxylato-8-oxo-5-thia-1-azabicyclo-[4.2.0]oct-2-en-3-yl)methyl)pyridinium iodide 423-260-0 100988-63-4 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 239-787-2 15690-38-7 2021 View substance registered dossier
Sanofi Aventis Deutschland GmbH Industriepark Höchst H 831 (Room A0472) z.Hd. Hr. Dr. Schwind 65926 Frankfurt am Main Germany Germany Active (6R-trans)-7-amino-3-[([5-(carboxymethyl)-4-methyl-2-thiazolyl]thio)methyl]-8-oxo- 5-thia-1-azabicyclo-[4.2.0]oct-2-en-2-carboxylic acid 403-690-5 111298-82-9 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 250-099-1 30246-33-4 2019 View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 619-847-8 111298-82-9 2021 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 258-907-4 53994-69-7 2019 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
Centrient Pharmaceuticals Netherlands B.V. Alexander Fleminglaan 1 2613 AX Delft Netherlands Netherlands Active (6R-trans)-7-amino-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 244-870-1 22252-43-3 - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 261-491-7 58909-56-1 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde 482-190-9 - - View substance registered dossier
- - - - (6RS,7RS)3,5,5,6,7,8,8-heptamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde 482-190-9 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate 949-377-1 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S)-3,10-dibromo-6-phenylindolo[1,2-c][1,3]benzoxazine 813-156-7 1392102-38-3 - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1) 605-420-3 165950-84-5 2018; 2020 View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (6S)-6-(propylamino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrobromide (1:1) 605-420-3 165950-84-5 2021 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Avara Shannon Pharmaceutical Services Limited Shannon Industrial Estate V14 FX09 Shannon Clare Ireland Ireland Cease Manufacture (6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1) 603-080-0 125572-93-2 2021 View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (6S)-6-{propyl[2-(2-thienyl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride (1:1) 603-080-0 125572-93-2 2019; 2020 View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S,12aR)-3,10-dibromo-6-phenyl-12,12a-dihydroindolo[1,2-c][1,3]benzoxazine 813-155-1 1585969-16-9 - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 435-680-1 - 2021 View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (6S,8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 615-123-0 7055-53-0 - View substance registered dossier

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