legislation-obligation

Substance Regulatory Obligations

OBL

Glycerol trinitrate

EC number: 200-240-8

CAS number: 55-63-0

Last updated: 28/08/2021
ECHA Legislation Regulatory Obligations

Regulatory obligations may exist for this substance under the legislations under ECHA’s remit or for which ECHA has delegated tasks (i.e. REACH, CLP, BPR, PIC, CAD / CMD, WFD, and POPs). Please check the substance Infocard.

Active Implantable Medical Devices Directive

Active Implantable Medical Devices Directive - Hazardous Substances

This list contains hazardous substances for purposes of Directive 90/385/EEC on active implantable medical devices, particularly as regards Article 3 and Annex I (Essential Requirements). This non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Name CAS EU CLP (1272/2008) EU_BA Directive 2000/54/EC EU REACH: List of SVHC
glycerol trinitrate; nitroglycerine
Unst. Expl.; Acute Tox. 2; Acute Tox. 1; STOT RE 2
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
CAD - Chemical Agents Directive

CAD - Chemical Agents Directive, Article 2(b)(i) - Hazardous Agents

This list contains a non-exhaustive inventory based on the list of substances with harmonised classification and labelling (i.e., Table 3 of Annex VI to the CLP Regulation 1272/2008/EC). While the harmonised list covers many hazardous substances, others not listed may also meet the classification criteria in accordance with the CLP Regulation.

Name CAS
glycerol trinitrate; nitroglycerine
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Construction Products Regulation

Construction Product Regulation - Annex I (3) - Hazardous Substances

This list contains a non-exhaustive inventory of substances taken from: (1) Table 3 of Annex VI to CLP; (2) the Candidate List of SVHCs; (3) Annex XIV of REACH (Authorisation List); (4) Annex XVII of REACH (Restrictions List); (5) F-gases subject to emission limits/reporting per Regulation 517/2014/EU; and (6) volatile organic compounds (VOCs) listed in the Ambient Air Directive 2008/50/EC. The basis of the list is Annex I(3) of the Construction Products Regulation 305/2011/EC, which stipulates that construction works must not have a high impact on human health or the environment as a result of: giving off toxic gas; emissions of dangerous substances, volatile organic compounds (VOC), greenhouse gases or dangerous particles into indoor or outdoor air; release of dangerous substances into drinking water, ground water, marine waters, surface waters or soil.

Name CAS EU CLP (1272/2008) EU REACH: Annex XIV EU REACH: List of SVHC EU REACH: Annex XVII EU FGG (517/2014) EU VOC (2008/50)
glycerol trinitrate; nitroglycerine
yes
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
yes

Construction Product Regulation - Article 6(5) - SDS and Declaration

This list contains a non-exhaustive inventory of substances originating from: (1) Table 3 of Annex VI to CLP (i.e., the list of harmonised substances); (2) the Candidate List of Substances of Very High Concern (SVHCs); and REACH Annex XIV (Authorisation List). This list is compiled on the basis of Article 6(5) of Regulation 305/2011/EC on Marketing of Construction Products. This provision requires SDSs and information on hazardous substances (i.e., SVHCs) contained in construction products be provided with the declaration of performance.

Name CAS EU REACH: Annex XIV EU REACH: List of SVHC
glycerol trinitrate; nitroglycerine
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Cosmetic Products Regulation

Cosmetic Products Regulation, Annex II - Prohibited Substances

This list contains substances which are banned from use in any cosmetic products marketed for sale or use in the European Union.

Ref No. Substance Identification Expressed As Product type, body parts Maximum Threshold Restriction(s) Notes  
Name EC Number CAS Molecular formula
253
Propane-1,2,3-triyl trinitrate
200-240-8
55-63-0
All cosmetic products
0 %
Details
End-of-Life Vehicles Directive

End-of-Life Vehicles Directive - Hazardous Substances

This list contains a non-exhaustive inventory of hazardous substances as defined by Article 2(11) of the End-of-Life Vehicles Directive 2000/53/EC. It is based on the relevant subset of substances with harmonised classification listed in Table 3 of Annex VI to the CLP Regulation 1272/2008/EC.

Name CAS EU CLP (1272/2008)
glycerol trinitrate; nitroglycerine
Unst. Expl.; Acute Tox. 2; Acute Tox. 1; STOT RE 2; Aquatic Chronic 2
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2; Aquatic Chronic 2
EU Ecolabel Regulation

Ecolabels - Restrictions for Hazardous Substances/Mixtures

This list contains a non-exhaustive inventory of substances based on the list of hazardous substances with harmonised classification and labelling (i.e. Table 3 of Annex VI to the CLP Regulation), and the Candidate List of substances of very high concern (SVHCs). Pursuant to Article 6(6) of the EU Ecolabel Regulation, the ecolabel must not be awarded to goods containing substances or mixtures classified according to the CLP as toxic; hazardous to the environment; and carcinogenic, mutagenic, or toxic for reproduction (CMRs). Nor are products allowed the ecolabel award when they contain SVHCs (per Article 57 of REACH). While the CLP's harmonised list contains many such substances, other ones not listed in Table 3 may also meet the criteria specified for classification under the CLP.

Name CAS Restriction(s) Expressed As Table 3 of Annex VI to CLP EU REACH: List of SVHC Physical form Substance Description  
glycerol trinitrate; nitroglycerine
yes
Details
glycerol trinitrate; nitroglycerine
>40 % phlegmatiser
yes
Details
General Product Safety Directive

General Product Safety Directive - Hazardous Substances

This list contains a non-exhaustive inventory of substances that fall within the European Union's hazardous substance definitions, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; (2) Annex III of Directive 2000/54/EC (Biological Agents); Candidate List of SVHCs; and REACH Annexes XIV and XVII (Authorisation and Restriction lists). They can be considered hazardous for purposes of the General Product Safety Directive 2001/95/EC.

Name CAS EU CLP (1272/2008) EU REACH: Annex XIV EU REACH: List of SVHC EU REACH: Annex XVII EU_BA Directive 2000/54/EC
glycerol trinitrate; nitroglycerine
yes
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
yes
In Vitro Diagnostic Medical Devices Directive

In Vitro Diagnostic Medical Devices Directive - Hazardous Substances

This list contains a non-exhaustive inventory of hazardous substances for purposes of essential requirements (Article 3 and Annex I) for general safety, design, manufacture and hazard communication of in vitro diagnostic medical devices. It is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Name CAS EU CLP (1272/2008) EU_BA Directive 2000/54/EC EU REACH: List of SVHC
glycerol trinitrate; nitroglycerine
Unst. Expl.; Acute Tox. 2; Acute Tox. 1; STOT RE 2
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
Inland Transport of Dangerous Goods Directive

Inland Transport of Dangerous Goods Directive, Annex I - ADR

This list contains the ADR Dangerous Goods List, as implemented by the European Union's Directive 2008/68/EC. This Directive applies the European Agreements on the international transport of dangerous goods by road (ADR) and inland waterways (ADN), and the regulations concerning the international carriage of dangerous goods by rail (RID).

Name CAS Class Labels Packing Group Packaging UN No. ADR tank Classification code Hazard identification no. Limited and excepted quantities Vehicle for tank carriage Portable tank and bulk containers Special provisions Special provisions for carriage Transport category (Tunnel restriction code) Notes  
Mixed packing provisions Special packing provisions Packing instructions Tank code Special provisions Excepted quantities Limited quantities Unit Instructions Special provisions bulk Loading, unloading & handling Operation Packages Tunnel restriction code Transport category
NITROGLYCERIN, DESENSITIZED with not less than 40% non-volatile water-insoluble phlegmatizer, by mass
55-63-0
1
1+6.1
MP20
PP53
PP54
PP57
PP58
P115
0143
1.1D
E0
266
271
CV1
CV2
CV3
CV28
S1
PP53
PP54
PP57
PP58
(B1000C)
1
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN SOLUTION IN ALCOHOL with more than 1% but not more than 10% nitroglycerin
55-63-0
1
1
MP20
PP45
PP55
PP56
PP59
PP60
P115
0144
1.1D
E0
358
CV1
CV2
CV3
S1
PP45
PP55
PP56
PP59
PP60
(B1000C)
1
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN SOLUTION IN ALCOHOL with not more than 1% nitroglycerin
55-63-0
3
3
II
MP2
PP5
P001
IBC02
1204
D
E0
1 l
601
S2
S14
PP5
(B)
2
Details
NITROGLYCERIN, SOLUTION IN ALCOHOL with more than 1% but not more than 5% nitroglycerin
55-63-0
3
3
II
MP2
P300
3064
D
E0
359
S2
S14
(B)
2
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, SOLID, N.O.S. with more than 2% but not more than 10% nitroglycerin, by mass
55-63-0
4.1
4.1
II
MP2
P099
IBC99
3319
D
E0
272
274
S14
(B)
2
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, LIQUID, FLAMMABLE, N.O.S. with not more than 30% nitroglycerin, by mass
55-63-0
3
3
MP2
P099
3343
D
E0
274
278
S2
S14
(B)
0
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, LIQUID, N.O.S. with not more than 30% nitroglycerin, by mass
55-63-0
3
3
II
MP2
P099
3357
D
E0
274
288
S2
S14
(B)
2
1 Not permitted to be carried in limited quantities
Details

Inland Transport of Dangerous Goods Directive, Annex II - RID

This list contains the RID Dangerous Goods List, as implemented by the European Union's Directive 2008/68/EC. This Directive applies the European Agreements on the international transport of dangerous goods by road (ADR) and inland waterways (ADN), and the regulations concerning the international carriage of dangerous goods by rail (RID).

Name CAS Class Labels Packing Group UN No. Classification code Express parcels Hazard identification number RID Tanks Limited and excepted quantities Packaging Portable tanks and bulk containers Transport category Special provisions for carriage Special provisions Notes  
Tank code Special provisions Excepted quantities Units Limited quantities Special packaging provisions Packaging instructions Mixed packing provisions Special provisions Instructions Loading, unloading & handling bulk Packages
NITROGLYCERIN, DESENSITIZED with not less than 40% non-volatile water-insoluble phlegmatizer, by mass
55-63-0
1
1+6.1(+15)
0143
1.1D
1.1D
E0
PP53
PP54
PP57
PP58
P115
MP20
1
CW1
CW28
W2
266
271
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN SOLUTION IN ALCOHOL with more than 1% but not more than 10% nitroglycerin
55-63-0
1
1(+13)
0144
1.1D
1.1D
E0
PP45
PP55
PP56
PP59
PP60
P115
MP20
1
CW1
W2
358
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN SOLUTION IN ALCOHOL with not more than 1% nitroglycerin
55-63-0
3
3
II
1204
D
CE7
33
E0
1 l
PP5
P001
IBC02
MP2
2
601
Details
NITROGLYCERIN, SOLUTION IN ALCOHOL with more than 1% but not more than 5% nitroglycerin
55-63-0
3
3
II
3064
D
33
E0
P300
MP2
2
359
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, SOLID, N.O.S. with more than 2% but not more than 10% nitroglvcerin, by mass
55-63-0
4.1
4.1
II
3319
D
CE10
40
E0
P099
IBC99
MP2
2
W1
272
274
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, LIQUID, FLAMMABLE, N.O.S. with not more than 30% nitroglycerin, by mass
55-63-0
3
3
3343
D
30/33
E0
P099
MP2
0
274
278
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, LIQUID, N.O.S. with not more than 30% nitroglycerin, by mass
55-63-0
3
3
II
3357
D
CE7
33
E0
P099
MP2
2
274
288
1 Not permitted to be carried in limited quantities
Details

Inland Transport of Dangerous Goods Directive, Annex III - ADN

This list contains the ADN Dangerous Goods List, as implemented by the European Union's Directive 2008/68/EC. This Directive establishes rules for the safe transport of dangerous goods between EU countries by road (ADR) and inland waterways (ADN), and the regulations concerning the international carriage of dangerous goods by rail (RID).

Name CAS Class Labels Packing Group UN No. or ID no. Carriage permitted Classification code Equipment required Limited and excepted quantities Number of blue cones/lights Provisions concerning loading, unloading and carriage Ventilation Remarks Special provisions Notes  
Excepted quantities Limited quantities Units Column (11c) Column (11b) Column (11a)
NITROGLYCERIN, DESENSITIZED with not less than 40% non-volatile water-insoluble phlegmatizer, by mass
55-63-0
1
1+6.1
0143
1.1D
PP
E0
3
HA01
HA02
HA03
LO01
266
271
802
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN SOLUTION IN ALCOHOL with more than 1% but not more than 10% nitroglycerin
55-63-0
1
1
0144
1.1D
PP
E0
3
HA01
HA02
HA03
LO01
358
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN SOLUTION IN ALCOHOL with not more than 1% nitroglycerin
55-63-0
3
3
II
1204
D
PP
EX
A
E0
1 l
1
VE01
601
Details
NITROGLYCERIN, SOLUTION IN ALCOHOL with more than 1% but not more than 5% nitroglycerin
55-63-0
3
3
II
3064
D
PP
EX
A
E0
1
VE01
359
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, SOLID, N.O.S. with more than 2% but not more than 10% nitroglycerin, by mass
55-63-0
4.1
4.1
II
3319
D
PP
E0
0
272
274
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, LIQUID, FLAMMABLE, N.O.S. with not more than 30% nitroglycerin, by mass
55-63-0
3
3
3343
D
PP
EX
A
E0
0
VE01
274
278
1 Not permitted to be carried in limited quantities
Details
NITROGLYCERIN MIXTURE, DESENSITIZED, LIQUID, N.O.S. with not more than 30% nitroglycerin, by mass
55-63-0
3
3
II
3357
D
PP
EX
A
E0
1
VE01
274
288
1 Not permitted to be carried in limited quantities
Details
Marine Environmental Policy Framework Directive

Marine Environmental Policy Framework Directive - Hazardous Substances

This list contains a non-exhaustive inventory of hazardous substances for purposes of the Marine Strategy Framework Directive, especially as it concerns Art. 3(8), and Annexes I and III. The listed substances meet the European Union's definitions as hazardous, as provided on: (1) Table 3 of Annex VI to the CLP Regulation (1272/2008/EC); (2) Annex III of Directive 2000/54/EC (Biological Agents); Candidate List of SVHCs; and REACH Annex XIV (Authorisation List).

Name CAS EU CLP (1272/2008) EU REACH: List of SVHC EU_BA Directive 2000/54/EC EU REACH: Annex XIV
glycerol trinitrate; nitroglycerine
yes
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
yes
Medical Devices Directive

Medical Devices Directive - Hazardous Substances

This list contains hazardous substances in accordance with the Medical Devices Directive's (MDD) design and construction requirements pursuant to Annex I, Part II (7) & (8) (i.e., chemical, physical and biological properties; and infection and microbial contamination). Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Name CAS EU CLP (1272/2008) EU_BA Directive 2000/54/EC EU REACH: List of SVHC
glycerol trinitrate; nitroglycerine
Unst. Expl.; Acute Tox. 2; Acute Tox. 1; STOT RE 2
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
OELs - Occupational Exposure Limits - 4th list

Occupational Exposure Limits - 4th list - Indicative OELVs

This list contains the indicative occupational exposure limit values (IOELVs) from Commission Directive 2017/164/EU. Member States are required to bring into force the laws, regulations and administrative provisions necessary to comply with this Directive, which establishes values for reference period of eight-hour time weighted average and for a short-term period of 15 minutes. The Directive adds limit values for 27 new chemical agents, and amends 6 existing ones established by earlier directives.

Name EC Number CAS Long-term Exposure Limit (LTEL) Values Short-term Exposure Limit (STEL) Values Expressed As Physical form Skin Designation Miscellaneous Notes  
mg/m3 ppm mg/m3 ppm
Glycerol trinitrate
200-240-8
55-63-0
0.095 mg/m3
0.01 ppm
0.19 mg/m3
0.02 ppm
Yes
2 Commission Directive (EU) 2017/164 of 31 January 2017 establishing a fourth list of indicative occupational exposure limit values pursuant to Council Directive 98/24/EC, and amending Commission Directives 91/322/EEC, 2000/39/EC and 2009/161/EU.
Details
Pressure Equipment Directive

Pressure Equipment Directive - Group 1 Fluids Hazardous Substances

This list contains a non-exhaustive inventory of hazardous substances based on Article 13(1)(a) of Directive 2014/68/EU, defining Group 1 fluids for purposes of classifying pressure equipment in accordance with the Directive. The list is derived from a subset of the substances with harmonised classifications, as listed on Table 3 of Annex VI to the CLP Regulation 1272/2008/EC.

Name CAS Substance Description Expressed As Physical form Restriction(s) Index EC Number Classifications
glycerol trinitrate; nitroglycerine
603-034-00-X
200-240-8
Unst. Expl.; Acute Tox. 1 (Oral); Acute Tox. 2 (Oral); Acute Tox. 1 (Dermal); Acute Tox. 2 (Dermal); Acute Tox. 1 (Inhalation); Acute Tox. 2 (Inhalation)
glycerol trinitrate; nitroglycerine
>40 % phlegmatiser
603-034-01-7
200-240-8
Expl. 1.1; Acute Tox. 1 (Oral); Acute Tox. 2 (Oral); Acute Tox. 1 (Dermal); Acute Tox. 2 (Dermal); Acute Tox. 1 (Inhalation); Acute Tox. 2 (Inhalation)
Protection of Young People Directive

Physical, Biological and Chemical Agents & Processes and Work

This list contains biological and chemical agents, in accordance with Art. 7 and points 2 and 3 of the Annex to Directive 94/33/EC, to which young persons (under 18 years of age) may not be exposed at the workplace. The list is a non-exhaustive inventory of such substances based on: 1) agents of risk groups 3 and 4 under Directive 2000/54/EC; 2) Table 3 of Annex VI to the CLP Regulation; 3) and Annex I of Directive 2004/37/EC.

Name CAS EC_YOUNG ECCAR Directive 2004/37/EC EU CLP (1272/2008) EU_BA Directive 2000/54/EC Notes  
glycerol trinitrate; nitroglycerine
Unst. Expl.; Acute Tox. 2; Acute Tox. 1; STOT RE 2
Details
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
Details
Safety and Health of Workers at Work Directive

Safety and Health of Workers at Work Directive - Hazardous Substances

This list contains a non-exhaustive inventory of substances that fall within the scope of the European Union's definition of hazardous chemical and biological substances, as provided on: (1) Table 3 of Annex VI to the CLP Regulation 1272/2008/EC; and (2) Annex III of Directive 2000/54/EC (Biological Agents). The EU's Occupational Safety and Health (OSH) Framework Directive 89/391/EEC applies to risks arising from chemical, physical and biological agents at the workplace.

Name CAS EU CLP (1272/2008) EU_BA Directive 2000/54/EC
glycerol trinitrate; nitroglycerine
Unst. Expl.; Acute Tox. 2; Acute Tox. 1; STOT RE 2
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
Expl. 1.1; Acute Tox. 2; Acute Tox. 1; STOT RE 2
Safety and/or Health Signs at Work Directive

Workplace Signs - minimum requirements & signs on containers and pipes

This list contains hazardous substances based on Table 3 of Annex VI to the CLP Regulation 1272/2008/EC. According to the annexes to Directive 92/58/EEC, storage areas and containers containing chemical substances or mixtures that are classified as hazardous according to the CLP Regulation must be duly marked and/or labeled. Directive 92/58/EEC requires employers to ensure proper signage is posted in areas where hazards cannot be avoided or reduced.

Name EC Number CAS Index Sustance Description Danger Symbols Restriction Physical form  
glycerol trinitrate; nitroglycerine
200-240-8
603-034-01-7
Exploding bomb
Skull and crossbones
Health hazard
>40 % phlegmatiser
Details
glycerol trinitrate; nitroglycerine
200-240-8
603-034-00-X
Exploding bomb
Skull and crossbones
Health hazard
Details
WFD - Waste Framework Directive

Waste Framework Directive, Annex III - Waste - Hazardous Properties

This list contains substances that have been assigned hazard property (HP) waste codes 1-15, as defined in terms of the hazard class and category, hazard (H) statement, and/or concentration limits provided in Annex III of the Waste Framework Directive 2008/98/EC. The classifications of the substances listed in the list are based on their harmonised classifications per Table 3 of Annex VI to the CLP Regulation 1272/2008/EC.

Name EC Number CAS EU CLP (1272/2008) HP Code Index
glycerol trinitrate; nitroglycerine
200-240-8
Acute Tox. 2
Acute Tox. 1
STOT RE 2
Aquatic Chronic 2
HP6 Acute Toxicity: waste which can cause acute toxic effects following oral or dermal administration, or inhalation exposure.
HP5 Specific Target Organ Toxicity (STOT)/Aspiration Toxicity: waste which can cause specific target organ toxicity either from a single or repeated exposure, or which cause acute toxic effects following aspiration.
HP14 Ecotoxic: waste which presents or may present immediate or delayed risks for one or more sectors of the environment.
603-034-00-X
glycerol trinitrate; nitroglycerine [>40 % phlegmatiser]
200-240-8
Expl. 1.1
Acute Tox. 2
Acute Tox. 1
STOT RE 2
Aquatic Chronic 2
HP1 Explosive: waste which is capable by chemical reaction of producing gas at such a temperature and pressure and at such a speed as to cause damage to the surroundings. Pyrotechnic waste, explosive organic peroxide waste and explosive self-reactive waste is included.
HP6 Acute Toxicity: waste which can cause acute toxic effects following oral or dermal administration, or inhalation exposure.
HP5 Specific Target Organ Toxicity (STOT)/Aspiration Toxicity: waste which can cause specific target organ toxicity either from a single or repeated exposure, or which cause acute toxic effects following aspiration.
HP14 Ecotoxic: waste which presents or may present immediate or delayed risks for one or more sectors of the environment.
603-034-01-7