PBT assessment list

ECHA’s persistence, bioaccumulation and toxicity (PBT) assessment list includes the substances undergoing a PBT/vPvB assessment that have been brought for discussion to ECHA’s PBT Expert Group.

Explanatory note

Inclusion in the list means that an informal hazard assessment for PBT/vPvB properties either is under development or has been completed since February 2013.

For each substance, the table shows the assessing or evaluating Member State (submitter), the outcome from the assessment, and the date of the latest update to the list entry.

Other process details and hazard assessment outcome documents are also available and can be accessed through the ‘Details’ icon.

One possible outcome of such an assessment is that a substance is considered not to have PBT/vPvB properties.

If the outcome is that the substance is considered to have PBT/vPvB properties, confirmation through the formal risk management and decision-making processes is needed before any regulatory action can be taken due to these properties.

The intentions of authorities to submit a dossier to the formal REACH and CLP processes are notified through the Registry of Intentions. All biocidal active substances have to undergo a formal PBT assessment. You can see the status of biocides assessments on the Biocidal Active Substances page.

Disclaimer

The information and views set out in the PBT assessment list and in the hazard assessment outcome documents are those of the evaluating authority and do not necessarily reflect the position or opinion of the other Member States or ECHA. Neither ECHA nor the evaluating authority nor any person acting on either of their behalves may be held liable for the use, which may be made of the information contained therein. Statements made or information contained in the documents are without prejudice to any formal regulatory activities that ECHA or the Member States may initiate at a later stage. PBT assessments and their outcomes are compiled on the basis of information available by the date of the publication of the document.

Last updated 11 April 2024. Database contains 231 unique substances/entries.

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Showing 51 - 100 of 236 results.

Substance name	EC / List no	CAS no	Authority	Outcome	Latest update
Reaction products of bis(4-methylpentan-2-yl)dithiophosphoric acid with phosphorus oxide, propylene oxide and amines, C12-14-alkyl (branched)	931-384-6	-	Slovenia	not PBT not vPvB	22-Jan-2019	Details
Reaction mass of 2-methylpent-2-ene and diisopropyl ether	906-484-8	-	Slovenia	not PBT not vPvB	07-Nov-2016	Details
HDI oligomers, isocyanurate	931-274-8	-	Slovenia	not PBT not vPvB	11-Jun-2018	Details
Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate	404-740-9	115895-09-5	Slovenia	Under development under SEV	22-Apr-2021	Details
mixture of two components: 1. N-(1,3- dimethylbutyl)-N´- phenyl-p-phenylenediamine 2. N1-(1,3-dimethylbutyl)- N4-(4-(1-methyl-1- phenylethyl)phenyl)ben zene-1,4-diamine	448-020-2	-	Slovakia	postponed	28-Apr-2022	Details
Bis(2-ethylhexyl)amine	203-372-4	106-20-7	Portugal	Under development under SEV	02-Jun-2020	Details
Biphenyl	202-163-5	92-52-4	Portugal	not PBT not vPvB	24-Feb-2021	Details
2,4,6-trichloro-1,3,5-triazine	203-614-9	108-77-0	Poland	not PBT not vPvB	24-Jan-2019	Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione	219-514-3	2451-62-9	Poland	not PBT not vPvB	02-Feb-2017	Details
Perfluorobutane sulfonic acid (PFBS) and its salts show/hide Potassium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonate EC / List no: 249-616-3 \| CAS no: 29420-49-3 Ammonium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonate EC / List no: 269-513-7 \| CAS no: 68259-10-9 magnesium perfluorobutanesulfonate EC / List no: 671-826-2 \| CAS no: 507453-86-3 lithium perfluorobutanesulfonate EC / List no: 671-827-8 \| CAS no: 131651-65-5 morpholinium perfluorobutanesulfonate EC / List no: 671-830-4 \| CAS no: 503155-89-3 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic acid EC / List no: 206-793-1 \| CAS no: 375-73-5 tetrabutyl-phosphonium nonafluoro-butane-1-sulfonate EC / List no: 444-440-5 \| CAS no: 220689-12-3 dimethyl(phenyl)sulfanium perfluorobutanesulfonate EC / List no: 452-310-4 \| CAS no: 220133-51-7 1-(4-butoxy-1-naphthyl)tetrahydrothiophenium nonafluorobutane-1-sulfonate EC / List no: 468-770-4 \| CAS no: - Triphenylsulfanium perfluorobutane sulfonate EC / List no: 478-340-8 \| CAS no: 144317-44-2 N,N,N-triethylethanaminium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate EC / List no: 700-536-1 \| CAS no: 25628-08-4 bis(4-tert-butylphenyl)iodonium nonafluorobutane-1-sulfonate EC / List no: 432-660-4 \| CAS no: 194999-85-4	799-977-0	-	Norway		17-Sep-2021	Details
Octamethyltrisiloxane	203-497-4	107-51-7	Norway	vPvB not PBT	22-Jun-2022	Details
N,N'-ethylenebis(3,4,5,6-tetrabromophthalimide)	251-118-6	32588-76-4	Norway	Under development under SEV	13-Oct-2017	Details
Hexamethyldisiloxane	203-492-7	107-46-0	Norway	Under development under SEV	31-Jan-2020	Details
Dodecamethylpentasiloxane	205-492-2	141-63-9	Norway	vPvB not PBT	22-Jun-2022	Details
Decamethyltetrasiloxane	205-491-7	141-62-8	Norway	vPvB not PBT	22-Jun-2022	Details
C16-(branched), C20-(branched) and C24-(branched)-alkanes	700-992-1	-	Norway	Under development under SEV	20-Dec-2016	Details
Bis(α,α-dimethylbenzyl) peroxide	201-279-3	80-43-3	Norway	Under development under SEV	01-Apr-2015	Details
2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs.	272-221-2	68784-12-3	Norway	not PBT not vPvB	01-Apr-2015	Details
2,4,6-tribromophenol	204-278-6	118-79-6	Norway	postponed	17-Mar-2022	Details
1,1,1,3,5,5,5-heptamethyltrisiloxane	217-496-1	1873-88-7	Norway	Under development	03-Nov-2022	Details
1,1,1,3,5,5,5-heptamethyl-3-[(trimethylsilyl)oxy]trisiloxane	241-867-7	17928-28-8	Norway	Under development under SEV	31-Jan-2020	Details
α,α,α,4-tetrachlorotoluene	226-009-1	5216-25-1	Netherlands	not PBT not vPvB	06-Nov-2015	Details
α,α,α,2-tetrachlorotoluene	218-377-7	2136-89-2	Netherlands	not PBT not vPvB	11-Dec-2015	Details
Tris(methylphenyl) phosphate	809-930-9	1330-78-5	Netherlands	not PBT not vPvB	22-Nov-2021	Details
Triclosan	222-182-2	3380-34-5	Netherlands	Under development under SEV	01-Apr-2015	Details
reaction mass of mixed (3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) phosphates, ammonium salt	700-161-3	-	Netherlands	Under development under SEV	01-Apr-2015	Details
Phenol, isopropylated, phosphate (3:1)	273-066-3	68937-41-7	Netherlands	Under development under SEV	12-Nov-2020	Details
O,O,O-triphenyl phosphorothioate	209-909-9	597-82-0	Netherlands	Under development under SEV	09-Sep-2016	Details
methylethylketone peroxide trimer	429-320-2	24748-23-0	Netherlands	Under development under SEV	26-May-2020	Details
Hexadec-1-ene	211-105-8	629-73-2	Netherlands	Under development	05-Jun-2015	Details
Ditolyl ether	248-948-6	28299-41-4	Netherlands	Under development under SEV	01-Apr-2015	Details
Disodium 2,2'-([1,1'-biphenyl]-4,4'-diyldivinylene)bis(benzenesulphonate)	248-421-0	27344-41-8	Netherlands	Under development	05-Jun-2015	Details
Bis[N-(4-{[4-(diethylamino)phenyl][4-(ethylamino)-1-naphthyl]methylene}cyclohexa-2,5-dien-1-ylidene)-N-ethylethanaminium] [mono and bis(dodecanyl, branched)]-(sulfonatophenoxy) benzenesulfonate	700-579-6	-	Netherlands	inconclusive	11-Apr-2024	Details
Benzene, mono-C11-C13-branched alkyl derivatives	810-801-4	-	Netherlands	Under development under SEV	27-Mar-2019	Details
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	246-678-3	25155-25-3	Netherlands	Under development under SEV	04-May-2015	Details
5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [1], 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane [2] covering any of the individual stereoisomers of [1] and [2] or any combination thereof show/hide Reaction mass of 5-[(2R)-butan-2-yl]-2-[(1R,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2R)-butan-2-yl]-2-[(1R,6R)-4,6-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1R,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1S,2R)-2,4-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane and 5-[(2S)-butan-2-yl]-2-[(1S,6R)-4,6-dimethylcyclohex-3-en-1-yl]-5-methyl-1,3-dioxane EC / List no: 700-927-7 \| CAS no: - 1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-06-9 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC / List no: - \| CAS no: - Reaction mass of 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane and 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC / List no: 413-720-9 \| CAS no: - 1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)- EC / List no: 601-499-3 \| CAS no: 117933-89-8 1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)- EC / List no: - \| CAS no: 186309-28-4 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-05-8 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-rel- EC / List no: - \| CAS no: 343934-04-3 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-09-2 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-rel- EC / List no: - \| CAS no: 343934-05-4 1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-04-7 1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-08-1 1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-03-6 1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans- EC / List no: - \| CAS no: 676367-07-0 1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis- EC / List no: - \| CAS no: 676367-02-5 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane EC / List no: - \| CAS no: -	-	-	Netherlands	vPvB	24-Jan-2019	Details
4,4'-Methylene-bis-(3-chloro-2,6-diethylaniline)	402-130-7	106246-33-7	Netherlands	Under development	18-Feb-2021	Details
2-hexyldecan-1-ol	219-370-1	2425-77-6	Netherlands	Under development	01-Apr-2015	Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine SR-245	426-040-2	25713-60-4	Netherlands	Under development	04-May-2015	Details
1-chloro-2-(chlorodiphenylmethyl)benzene	255-647-3	42074-68-0	Netherlands	postponed	10-Mar-2022	Details
1,2-dichloro-4-(trichloromethyl)benzene	235-869-7	13014-24-9	Netherlands	postponed	10-Mar-2022	Details
Isoheptane	250-610-8	31394-54-4	Latvia	not PBT not vPvB	11-Jun-2018	Details
Trixylyl phosphate	246-677-8	25155-23-1	Italy	inconclusive	07-Apr-2022	Details
Quaternary ammonium compounds, tri-C8-10-alkylmethyl, chlorides	264-120-7	63393-96-4	Italy	inconclusive	09-Mar-2023	Details
Benzene, mono-C10-13-alkyl derivs., distn. residues	284-660-7	84961-70-6	Italy	inconclusive	07-Apr-2022	Details
Benzene, C10-13-alkyl derivs.	267-051-0	67774-74-7	Italy	Under development	04-May-2015	Details
2-[(4-methoxy-2-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	229-419-9	6528-34-3	Italy	Under development under SEV	02-Jun-2020	Details
2-[(4-chloro-2-nitrophenyl)azo]-N-(2-chlorophenyl)-3-oxobutyramide	229-355-1	6486-23-3	Italy	Under development under SEV	02-Jun-2020	Details
2-[(2-methoxy-4-nitrophenyl)azo]-N-(2-methoxyphenyl)-3-oxobutyramide	228-768-4	6358-31-2	Italy	Under development under SEV	02-Jun-2020	Details
2,5-di-tert-pentylhydroquinone	201-222-2	79-74-3	Italy	Under development under SEV	31-Jan-2020	Details

Showing 51 - 100 of 236 results.

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