pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 19 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
2-naphthylamine
202-080-4
91-59-8
Carc. 1A
yes
 Details
2-Naphthylammonium chloride
210-313-6
612-52-2
Carc. 1A
yes
 Details
4-(4-aminophenyl)aniline;dihydrochloride
208-519-6
531-85-1
Carc. 1A
yes
 Details
4-(4-aminophenyl)aniline;sulfuric acid
208-520-1
531-86-2
Carc. 1A
yes
 Details
acetic acid;naphthalen-2-amine
209-030-0
553-00-4
Carc. 1A
yes
 Details
arsenic acid and it salts with the exception of those specified elsewhere in this Annex
-
-
Carc. 1A
yes
 Details
Asbestos fibres
show/hide
Asbestos, amosite EC / List no: 601-801-3 | CAS no: 12172-73-5
Asbestos, chrysotile EC / List no: 601-650-3 | CAS no: 12001-29-5
Asbestos, anthophyllite EC / List no: 616-472-1 | CAS no: 77536-67-5
Asbestos, tremolite EC / List no: 616-473-7 | CAS no: 77536-68-6
Asbestos, crocidolite EC / List no: 601-649-8 | CAS no: 12001-28-4
Asbestos, actinolite EC / List no: 616-471-6 | CAS no: 77536-66-4
-
-
Carc. 1A
yes
 Details
Asbestos, actinolite
616-471-6
77536-66-4
Carc. 1A
yes
 Details
Asbestos, anthophyllite
616-472-1
77536-67-5
Carc. 1A
yes
 Details
Asbestos, chrysotile
-
132207-32-0
Carc. 1A
yes
 Details
Asbestos, grunerite
601-801-3
12172-73-5
Carc. 1A
yes
 Details
Asbestos, tremolite
616-473-7
77536-68-6
Carc. 1A
yes
 Details
Benzidine acetate
252-984-8
36341-27-2
Carc. 1A
yes
 Details
benzidine sulphate
244-236-4
21136-70-9
Carc. 1A
yes
 Details
benzidine; 1,1'-biphenyl-4,4'-diamine; 4,4'-diaminobiphenyl; biphenyl-4,4'-ylenediamine
202-199-1
92-87-5
Carc. 1A
yes
 Details
biphenyl-4-ylamine; xenylamine; 4-aminobiphenyl
202-177-1
92-67-1
Carc. 1A
yes
 Details
bis(chloromethyl) ether; oxybis(chloromethane)
208-832-8
542-88-1
Carc. 1A
yes
 Details
bunsenite
-
34492-97-2
Carc. 1A
yes
 Details
chlormethyl methyl ether; chlorodimethyl ether
203-480-1
107-30-2
Carc. 1A
yes
 Details
cobalt dimolybdenum nickel octaoxide
268-169-5
68016-03-5
Carc. 1A
yes
 Details
cobalt lithium nickel oxide
442-750-5
113066-89-0
Carc. 1A
yes
 Details
cobalt nickel dioxide
261-346-8
58591-45-0
Carc. 1A
yes
 Details
cobalt nickel gray periclase; C.I. Pigment Black 25; C.I. 77332
This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77332.
269-051-6
68186-89-0
Carc. 1A
yes
 Details
cobalt nickel oxide
620-395-9
12737-30-3
Carc. 1A
yes
 Details
dialuminium nickel tetraoxide
234-454-8
12004-35-2
Carc. 1A
yes
 Details
diammonium nickel hexacyanoferrate
-
74195-78-1
Carc. 1A
yes
 Details
diarsenic pentaoxide; arsenic pentoxide; arsenic oxide
215-116-9
1303-28-2
Carc. 1A
yes
 Details
diarsenic trioxide; arsenic trioxide
215-481-4
1327-53-3
Carc. 1A
yes
 Details
dinickel boride
234-494-6
12007-01-1
Carc. 1A
yes
 Details
dinickel diphosphate
238-426-6
14448-18-1
Carc. 1A
yes
 Details
dinickel hexacyanoferrate
238-946-3
14874-78-3
Carc. 1A
yes
 Details
dinickel orthosilicate
237-411-1
13775-54-7
Carc. 1A
yes
 Details
dinickel phosphide
234-828-0
12035-64-2
Carc. 1A
yes
 Details
dinickel silicide
235-033-1
12059-14-2
Carc. 1A
yes
 Details
dinickel trioxide
215-217-8
1314-06-3
Carc. 1A
yes
 Details
diphosphoric acid, nickel(II) salt
-
19372-20-4
Carc. 1A
yes
 Details
Distillates (petroleum), acid-treated heavy naphthenic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons obtained as a raffinate from a sulfuric acid treating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100 °F (19cSt at 40 °C). It contains relatively few normal paraffins.]
A complex combination of hydrocarbons obtained as a raffinate from a sulfuric acid treating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100°F (19cSt at 40°C). It contains relatively few normal paraffins.
265-117-3
64742-18-3
Carc. 1A
yes
 Details
Distillates (petroleum), acid-treated heavy paraffinic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons btained as a raffinate from a sulfuric acid process. It consists predomi nantly of saturated hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil having a viscosity of a least 100 SUS at 100°F (19cSt at 40 °C).]
A complex combination of hydrocarbons obtained as a raffinate from a sulfuric acid process. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil having a viscosity of at least 100 SUS at 100°F (19cSt at 40°C).
265-119-4
64742-20-7
Carc. 1A
yes
 Details
Distillates (petroleum), acid-treated light naphthenic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons obtained as a raffinate from a sulfuric acid treating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS at 100 °F (19cSt at 40 °C). It contains relatively few normal paraffins.]
A complex combination of hydrocarbons obtained as a raffinate from a sulfuric acid treating process. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS at 100°F (19cSt at 40°C). It contains relatively few normal paraffins.
265-118-9
64742-19-4
Carc. 1A
yes
 Details
Distillates (petroleum), acid-treated light paraffinic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons obtained as a raffinate from a sulfuric acid treating process. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oi having aviscosity of less than 100 SUS at 100 °F (19cSt at 40°C).]
A complex combination of hydrocarbons obtained as a raffinate from a sulfuric acid treating process. It consists predominantly of saturated hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil having a viscosity of less than 100 SUS at 100°F (19cSt at 40°C).
265-121-5
64742-21-8
Carc. 1A
yes
 Details
Distillates (petroleum), chemically neutralized heavy naphthenic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100 °F (19cSt at 40 °C). It contains relatively few normal paraffins.]
A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100°F (19cSt at 40°C). It contains relatively few normal paraffins.
265-135-1
64742-34-3
Carc. 1A
yes
 Details
Distillates (petroleum), chemically neutralized heavy paraffinic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons obtained from a treating proces to remove acidic materials. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100 °F (19cSt at 40 °C). It contains a relatively large proportion of aliphatic hydrocarbons.]
A complex combination of hydrocarbons obtained from a treating process to remove acidic materials. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100°F (19cSt at 40°C). It contains a relatively large proportion of aliphatic hydrocarbons.
265-127-8
64742-27-4
Carc. 1A
yes
 Details
Distillates (petroleum), chemically neutralized light naphthenic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS a 100 °F (19cSt at 40 °C). It contains relatively few normal paraffins.]
A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS at 100°F (19cSt at 40°C). It contains relatively few normal paraffins.
265-136-7
64742-35-4
Carc. 1A
yes
 Details
Distillates (petroleum), chemically neutralized light paraffinic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity less than 100 SUS at 100 °F (19cSt at 40 °C).]
A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity less than 100 SUS at 100°F (19cSt at 40°C).
265-128-3
64742-28-5
Carc. 1A
yes
 Details
Distillates (petroleum), heavy naphthenic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100 °F (19cSt at 40 °C). It contains relatively few normal paraffins.]
A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100°F (19cSt at 40°C). It contains relatively few normal paraffins.
265-054-1
64741-53-3
Carc. 1A
yes
 Details
Distillates (petroleum), light naphthenic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS at 100 °F (19cSt at 40 °C). It contains relatively few normal paraffins.]
A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS at 100°F (19cSt at 40°C). It contains relatively few normal paraffins.
265-053-6
64741-52-2
Carc. 1A
yes
 Details
Distillates (petroleum), light paraffinic; Unrefined or mildly refined baseoil [A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS at 100 °F (19cSt at 40 °C). It contains a relatively large proportion of saturated aliphatic hydrocarbons normally present in this distillation range of crude oil.]
A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C15 through C30 and produces a finished oil with a viscosity of less than 100 SUS at 100°F (19cSt at 40°C). It contains a relatively large proportion of saturated aliphatic hydrocarbons normally present in this distillation range of crude oil.
265-051-5
64741-50-0
Carc. 1A
yes
 Details
Distillates(petroleum), heavy paraffinic; Unrefined ormildly refined baseoil [A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100 °F (19cSt at 40 °C). It contains a relatively large proportion of saturated aliphatic hydrocarbons.]
A complex combination of hydrocarbons produced by vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C20 through C50 and produces a finished oil with a viscosity of at least 100 SUS at 100°F (19cSt at 40°C). It contains a relatively large proportion of saturated aliphatic hydrocarbons.
265-052-0
64741-51-1
Carc. 1A
yes
 Details
erionite
620-440-2
12510-42-8
Carc. 1A
yes
 Details
lithium nickel dioxide
620-400-4
12031-65-1
Carc. 1A
yes
 Details
molybdenum nickel hydroxide oxide phosphate
268-585-7
68130-36-9
Carc. 1A
yes
 Details
molybdenum nickel oxide
-
12673-58-4
Carc. 1A
yes
 Details
molybdenum nickel tetraoxide
238-034-5
14177-55-0
Carc. 1A
yes
 Details
nickel arsenide
248-169-1
27016-75-7
Carc. 1A
yes
 Details
nickel barium titanium primrose priderite; C.I. Pigment Yellow 157; C.I. 77900
This substance is identified in the Colour Index by Colour Index Constitution Number, C.I. 77900.
271-853-6
68610-24-2
Carc. 1A
yes
 Details
nickel bis(dihydrogen phosphate)
242-522-3
18718-11-1
Carc. 1A
yes
 Details
nickel bis(phosphinate)
238-511-8
14507-36-9
Carc. 1A
yes
 Details
nickel boride
235-723-2
12619-90-8
Carc. 1A
yes
 Details
nickel boride (NiB)
234-493-0
12007-00-0
Carc. 1A
yes
 Details
nickel boron phosphide
-
65229-23-4
Carc. 1A
yes
 Details
nickel chromate
238-766-5
14721-18-7
Carc. 1A
yes
 Details
nickel diarsenide
235-103-1
12068-61-0
Carc. 1A
yes
 Details
nickel dicyanide
209-160-8
557-19-7
Carc. 1A
yes
 Details
nickel dioxide
234-823-3
12035-36-8
Carc. 1A
yes
 Details
nickel disilicide
235-379-3
12201-89-7
Carc. 1A
yes
 Details
nickel divanadium hexaoxide
257-970-5
52502-12-2
Carc. 1A
yes
 Details
nickel hydrogen phosphate
238-278-2
14332-34-4
Carc. 1A
yes
 Details
nickel matte
Product of blowing smelted nickel ore in a converter to lower the iron content.
273-749-6
69012-50-6
Carc. 1A
yes
 Details
nickel monoxide
215-215-7
1313-99-1
Carc. 1A
yes
 Details
nickel oxalate
208-933-7
547-67-1
Carc. 1A
yes
 Details
nickel oxide
234-323-5
11099-02-8
Carc. 1A
yes
 Details
nickel phosphinate
252-840-4
36026-88-7
Carc. 1A
yes
 Details
nickel selenide
215-216-2
1314-05-2
Carc. 1A
yes
 Details
nickel silicate (3:4)
250-788-7
31748-25-1
Carc. 1A
yes
 Details
nickel telluride
235-260-6
12142-88-0
Carc. 1A
yes
 Details
nickel tellurium tetraoxide
239-974-9
15852-21-8
Carc. 1A
yes
 Details
nickel tellurium trioxide
239-967-0
15851-52-2
Carc. 1A
yes
 Details
nickel tin trioxide; nickel stannate
234-824-9
12035-38-0
Carc. 1A
yes
 Details
nickel titanium oxide
235-752-0
12653-76-8
Carc. 1A
yes
 Details
nickel titanium trioxide
234-825-4
12035-39-1
Carc. 1A
yes
 Details
nickel triuranium decaoxide
239-876-6
15780-33-3
Carc. 1A
yes
 Details
nickel tungsten tetraoxide
238-032-4
14177-51-6
Carc. 1A
yes
 Details
nickel zirkonium trioxide
274-755-1
70692-93-2
Carc. 1A
yes
 Details
nickel(II) selenite
233-263-7
10101-96-9
Carc. 1A
yes
 Details
nickel(II) silicate
244-578-4
21784-78-1
Carc. 1A
yes
 Details
nickel(II) sulfite
231-827-7
7757-95-1
Carc. 1A
yes
 Details
olivine, nickel green
An inorganic pigment that is the reaction product of high temperature calcination in which nickel (II) oxide and silicon oxide in varying amounts are homogeneously and ionically interdiffused to form a crystalline matrix of olivine. Its composition may include any one or a combination of the modifiers alkali or alkaline earth halides.
271-112-7
68515-84-4
Carc. 1A
yes
 Details
oxalic acid, nickel salt
243-867-2
20543-06-0
Carc. 1A
yes
 Details
phosphoric acid, calcium nickel salt
-
17169-61-8
Carc. 1A
yes
 Details
salts of 2-naphthylamine
show/hide
2-naphthylammonium chloride EC / List no: 210-313-6 | CAS no: 612-52-2
2-naphthylammonium acetate EC / List no: 209-030-0 | CAS no: 553-00-4
-
-
Carc. 1A
yes
 Details
salts of benzidine
show/hide
Benzidine EC / List no: 202-199-1 | CAS no: 92-87-5
Salts of benzidine EC / List no: - | CAS no: -
-
-
Carc. 1A
yes
 Details
salts of biphenyl-4-ylamine; salts of xenylamine; salts of 4-aminobiphenyl
-
-
Carc. 1A
yes
 Details
silicic acid, nickel salt
253-461-7
37321-15-6
Carc. 1A
yes
 Details
Tar brown-coal [An oil distilled from brown-coal tar. Composed primarily of aliphatic, naphthenic and one-to three-ring aromatic hydrocarbons, their alkyl derivates, heteroaromatics and one-and two-ring phenols boiling in the range of approximately 150°C to 360 °C (302°F to 680°F).]
An oil distilled from brown-coal tar. Composed primarily of aliphatic, naphthenic and one- to three-ring aromatic hydrocarbons, their alkyl derivatives, heteroaromatics and one- and two-ring phenols boiling in the range of approximately 150°C to 360°C (302°F to 680°F).
309-885-0
101316-83-0
Carc. 1A
yes
 Details
Tar, brown-coal, low-temp. [A tar obtained from low temperature carbonization and low temperature gasification of brown coal. Composed primarily of aliphatic, naphthenic and cyclic aromatic hydrocarbons, heteroaromatic hydrocarbons and cyclic phenols.]
A tar obtained from low temperature carbonization and low temperature gasification of brown coal. Composed primarily of aliphatic, naphthenic and cyclic aromatic hydrocarbons, heteroaromatic hydrocarbons and cyclic phenols.
309-886-6
101316-84-1
Carc. 1A
yes
 Details
Tar, coal, high-temp.; Coal tar [The condensation product obtained by cooling, to approxi mately ambient temperature, the gas evolved in the high temperature (greater than 700 °C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of a complex mixture of condensed ring aromatic hydrocarbons. May contain minor amounts of phenolic compounds and aromatic nitrogen bases.]
The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in the high temperature (greater than 700°C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of a complex mixture of condensed ring aromatic hydrocarbons. May contain minor amounts of phenolic compounds and aromatic nitrogen bases.
266-024-0
65996-89-6
Carc. 1A
yes
 Details
Tar, coal, low-temp.; Coal oil [The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in low temperature (less than 700 °C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of condensed ring aromatic hydrocarbons, phenolic compounds, aromatic nitrogen bases, and their alkyl derivatives.]
The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in low temperature (less than 700°C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of condensed ring aromatic hydrocarbons, phenolic compounds, aromatic nitrogen bases, and their alkyl derivatives.
266-025-6
65996-90-9
Carc. 1A
yes
 Details
Tar, coal; Coal tar [The by-product from the destructive distillation of coal. Almost black semisolid. A complex combination of aromatic hydrocarbons, phenolic compounds, nitrogen bases and thiophene.]
The by-product from the destructive distillation of coal. Almost black semisolid. A complex combination of aromatic hydrocarbons, phenolic compounds, nitrogen bases and thiophene.
232-361-7
8007-45-2
Carc. 1A
yes
 Details
triethyl arsenate
TRIETHYLARSENAT; TRIETHYLARSENATE; TRIETHYLARSENATE (TEASAT)
427-700-2
15606-95-8
Carc. 1A
yes
 Details
trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-)
235-688-3
12519-85-6
Carc. 1A
yes
 Details
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