pregnant-women-protection

Protection of Pregnant and Breastfeeding Workers Directive, Annex I+II

EU. Chemical Agents: Annexes I & II, Directive 92/85/EEC on Pregnant Workers, 28 November 1992 (updated by table 3 of Annex VI to CLP, 5 October 2018)

This list contains a non-exhaustive inventory of substances to which pregnant workers and workers who have recently given birth or are breastfeeding may not be exposed. Employers are obligated to prevent the exposure of these workers to any agents that may have adverse health effects on either mother or child. The inventory originates from Table 3 of Annex VI to the CLP.

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Last updated 26 April 2024. Database contains 2100 unique substances/entries.
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Substance Name
EC No.
CAS No.
CLP (1272/2008) CMRs
ECCAR Directive 2004/37/EC
 
Tar bases, coal, quinoline derivs. fraction; Distillate Bases
274-560-1
70321-67-4
Carc. 1B; Muta. 1B
yes
 Details
tellurium dioxide
231-193-1
7446-07-3
Repr. 1B
yes
 Details
tert-butyl hydroperoxide
200-915-7
75-91-2
Muta. 2
Details
tetrahydro-1,3-dimethyl-1H-pyrimidin-2-one; dimethyl propyleneurea
230-625-6
7226-23-5
Repr. 2
Details
tetramethrin (ISO); (1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate
231-711-6
7696-12-0
Carc. 2; STOT SE 2
Details
trichloroethylene; trichloroethene
201-167-4
79-01-6
Carc. 1B; Muta. 2
yes
 Details
trilead bis(orthophosphate)
231-205-5
7446-27-7
Repr. 1A
yes
 Details
trinickel bis(arsenite)
-
74646-29-0
Carc. 1A
yes
 Details
vinyl chloride; chloroethylene
200-831-0
75-01-4
Carc. 1A
yes
 Details
(2-ethylhexanoato-O)(isodecanoato-O)nickel
284-351-7
84852-39-1
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
(2-ethylhexanoato-O)(isononanoato-O)nickel
287-470-2
85508-45-8
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
(4-hydrazinophenyl)-N-methylmethanesulfonamide hydrochloride
SULPHAZINE
406-090-1
81880-96-8
Muta. 2
Details
(4-phenylbutyl)phosphinic acid
420-450-5
86552-32-1
Carc. 2
Details
(E)-3-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
CP-166,221
428-010-4
82413-20-5
Carc. 2; Repr. 1B
yes
 Details
(isodecanoato-O)(isononanoato-O)nickel
284-348-0
84852-36-8
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
(isodecanoato-O)(isooctanoato-O)nickel
285-909-2
85166-19-4
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
(isononanoato-O)(isooctanoato-O)nickel
287-471-8
85508-46-9
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
(isononanoato-O)(neodecanoato-O)nickel
287-592-6
85551-28-6
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
(isooctanoato-O)(neodecanoato-O)nickel
284-347-5
84852-35-7
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
(RS)-4-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole; medetomidine
811-718-6
86347-14-0
STOT SE 1
Details
1,2-benzenedicarboxylic acid, dipentylester, branched and linear
284-032-2
84777-06-0
Repr. 1B
yes
 Details
1-vinyl-2-pyrrolidone
201-800-4
88-12-0
Carc. 2
Details
2,2'-((3,3', 5,5'-tetramethyl-(1,1'-biphenyl)-4,4'-diyl)-bis(oxymethylene))-bis-oxirane
EPIKOTE YX4000; EPIKOTE YX4000H; YX-4000
413-900-7
85954-11-6
Carc. 2
Details
2,4,6-trichlorophenol
201-795-9
88-06-2
Carc. 2
Details
2,6-xylidine; 2,6-dimethylaniline
201-758-7
87-62-7
Carc. 2
Details
2-(4-tert-butylbenzyl)propionaldehyde
201-289-8
80-54-6
Repr. 1B
yes
 Details
2-(isocyanatosulfonylmethyl)benzoic acid methyl ester; (alt.):methyl 2-(isocyanatosulfonylmethyl)benzoate
MCPSI
410-900-9
83056-32-0
Muta. 2
Details
2-ethylhexanoato-O)(neodecanoato-O)nickel
285-698-7
85135-77-9
Carc. 1A; Muta. 2; Repr. 1B
yes
 Details
2-ethylhexyl[[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]thio]acetate
279-452-8
80387-97-9
Repr. 1B
yes
 Details
2-methyl-m-phenylenediamine; 2,6-toluenediamine
212-513-9
823-40-5
Muta. 2
Details
2-nitrotoluene
201-853-3
88-72-2
Carc. 1B; Muta. 1B; Repr. 2
yes
 Details
3-(piperazin-1-yl)-benzo[d]isothiazole hydrochloride
421-310-6
87691-88-1
Repr. 2
Details
4,4'-methylenedi-o-toluidine
212-658-8
838-88-0
Carc. 1B
yes
 Details
4,4'-sulphonyldiphenol; bisphenol S
201-250-5
80-09-1
Repr. 1B
yes
 Details
4-methylimidazole
212-497-3
822-36-6
Carc. 1B; Repr. 1B
yes
 Details
4-nonylphenol, branched
284-325-5
84852-15-3
Repr. 2
Details
6-hydroxy-1-(3-isopropoxypropyl)-4-methyl-2-oxo-5-[4-(phenylazo)phenylazo]-1,2-dihydro-3-pyridinecarbonitrile
ARANCIO DISPERSO 149; C.I. DISPERSE ORANGE 149; DISPERS ORANGE 149; DISPERSE ORANGE 149; ORANGE DISPERSE 149; TERASIL GOLDGELB 2RS
400-340-3
85136-74-9
Carc. 1B
yes
 Details
alkanes, C10-13, chloro; chlorinated paraffins, C10-13
287-476-5
85535-84-8
Carc. 2
Details
alkanes, C14-17, chloro; chlorinated paraffins, C14-17
287-477-0
85535-85-9
Details
anthraquinone
201-549-0
84-65-1
Carc. 1B
yes
 Details
antu (ISO); 1-(1-naphthyl)-2-thiourea
201-706-3
86-88-4
Carc. 2
Details
BBP; benzyl butyl phthalate e
201-622-7
85-68-7
Repr. 1B
yes
 Details
benfuracarb (ISO); ethyl N-[2,3-dihydro-2,2-dimethylbenzofuran-7-yloxycarbonyl(methyl)aminothio]-N-isopropyl-β-alaninate
617-356-3
82560-54-1
Repr. 2
Details
bifenthrin (ISO); (2-methylbiphenyl-3-yl)methylrel-(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate
617-373-6
82657-04-3
Carc. 2
Details
bis(α,α-dimethylbenzyl) peroxide
201-279-3
80-43-3
Repr. 1B
yes
 Details
bisphenol A; 4,4'-isopropylidenediphenol
201-245-8
80-05-7
Repr. 1B
yes
 Details
C.I. Solvent Yellow 14; 1-phenylazo-2-naphthol
212-668-2
842-07-9
Carc. 2; Muta. 2
Details
camphechlor (ISO); toxaphene
232-283-3
8001-35-2
Carc. 2
Details
chlozolinate (ISO); ethyl (RS)-3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-oxazolidine-5-carboxylate
282-714-4
84332-86-5
Carc. 2
Details
chrysoidine C10-14-alkyl derivatives; benzenesulfonic acid, mono-C10-14-alkyl derivatives, compounds; with 4-(phenylazo)-1,3-benzenediamine
286-946-7
85407-90-5
Muta. 2
Details
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